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Original Article

Self-microemulsifying drug delivery system improves curcumin dissolution and bioavailability

, , &
Pages 15-23 | Received 25 Nov 2009, Accepted 25 Apr 2010, Published online: 25 Aug 2010

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Read on this site (28)

Fangli Chen, Feifei Zhao, Jieying Zhang, Li Yu, Guiju Zhang, Changyao Liu, Nan Wang & Baocai Xu. (2022) Development of polyglycerol fatty acid ester-based low-energy nanoemulsion for the improvement of curcumin stability. Journal of Dispersion Science and Technology 43:4, pages 605-611.
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Umesh Kannamangalam Vijayan, Sadineni Varakumar, Sushant Sole & Rekha S. Singhal. (2020) Enhancement of loading and oral bioavailability of curcumin loaded self-microemulsifying lipid carriers using Curcuma oleoresins. Drug Development and Industrial Pharmacy 46:6, pages 889-898.
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Weidong Liu, Yingjie Zhai, Xueyuan Heng, Feng Yuan Che, Wenjun Chen, Dezhong Sun & Guangxi Zhai. (2016) Oral bioavailability of curcumin: problems and advancements. Journal of Drug Targeting 24:8, pages 694-702.
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Zhe Wang, Wei Sun, Cheng-Ke Huang, Li Wang, Meng-Ming ia, Xiao Cui, Guo-Xin Hu & Zeng-Shou Wang. (2015) Inhibitory effects of curcumin on activity of cytochrome P450 2C9 enzyme in human and 2C11 in rat liver microsomes. Drug Development and Industrial Pharmacy 41:4, pages 613-616.
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Nguyen Duc Hanh, Ampol Mitrevej, Korbtham Sathirakul, Penchom Peungvicha & Nuttanan Sinchaipanid. (2015) Development of phyllanthin-loaded self-microemulsifying drug delivery system for oral bioavailability enhancement. Drug Development and Industrial Pharmacy 41:2, pages 207-217.
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Amrita Bajaj, Monica R. P. Rao, Ishwar Khole & Ghansham Munjapara. (2013) Self-nanoemulsifying drug delivery system of cefpodoxime proxetil containing tocopherol polyethylene glycol succinate. Drug Development and Industrial Pharmacy 39:5, pages 635-645.
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Saujanya Gosangari & Tatyana Dyakonov. (2013) Enhanced dissolution performance of curcumin with the use of supersaturatable formulations. Pharmaceutical Development and Technology 18:2, pages 475-480.
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Jia-Xiao Zhu, Dan Tang, Liang Feng, Zhao-Guang Zheng, Ru-Shang Wang, An-Guo Wu, Ting-Ting Duan, Bao He & Quan Zhu. (2013) Development of self-microemulsifying drug delivery system for oral bioavailability enhancement of berberine hydrochloride. Drug Development and Industrial Pharmacy 39:3, pages 499-506.
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Jae Kuk Ryu & Sun Dong Yoo. (2012) Preparation and evaluation of bicyclol microemulsions for enhanced oral bioavailability. Drug Development and Industrial Pharmacy 38:11, pages 1313-1318.
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Yu Bao, Shanshan Li, Lian Liu, Yuxia Luan, Guimei Lin & Wei Shao. (2012) Carmofur-Loaded Pluronic P123 Polymeric Micelles: Preparation and Characterization. Journal of Dispersion Science and Technology 33:4, pages 617-621.
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Weijia Zheng, Akash Jain, Dimitris Papoutsakis, Rose-Marie Dannenfelser, Riccardo Panicucci & Sudhakar Garad. (2012) Selection of oral bioavailability enhancing formulations during drug discovery. Drug Development and Industrial Pharmacy 38:2, pages 235-247.
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Myung Joo Kang, Soo Young Jung, Woo Heon Song, Jun Sang Park, Sung-Up Choi, Kyung Taek Oh, Hyung-Kyoon Choi, Young Wook Choi, Jaehwi Lee, Beom-Jin Lee & Sang-Cheol Chi. (2011) Immediate release of ibuprofen from Fujicalin®-based fast-dissolving self-emulsifying tablets. Drug Development and Industrial Pharmacy 37:11, pages 1298-1305.
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Minghui Sun, Luqin Si, Xuezhen Zhai, Zhaoze Fan, Yiming Ma, Rui Zhang & Xiangliang Yang. (2011) The influence of co-solvents on the stability and bioavailability of rapamycin formulated in self-microemulsifying drug delivery systems. Drug Development and Industrial Pharmacy 37:8, pages 986-994.
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