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Research Article

The use of spray-drying to enhance celecoxib solubility

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Pages 1463-1472 | Received 19 Nov 2010, Accepted 07 May 2011, Published online: 27 Jun 2011

Keep up to date with the latest research on this topic with citation updates for this article.

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Fatemeh Sadeghi, Hossein Kamali, Sepideh Kouhestanian, Farzin Hadizadeh, Ali Nokhodchi & Hadi Afrasiabi Garekani. (2022) Supercritical CO2 versus water as an antisolvent in the crystallization process to enhance dissolution rate of curcumin. Pharmaceutical Development and Technology 27:10, pages 999-1008.
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Eric Lyng, Robert Havenaar, Prathap Shastri, Lucy Hetsco, Andrew Vick & John Sagartz. (2016) Increased bioavailability of celecoxib under fed versus fasted conditions is determined by postprandial bile secretion as demonstrated in a dynamic gastrointestinal model. Drug Development and Industrial Pharmacy 42:8, pages 1334-1339.
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Nizar Al-Zoubi, Ghada Al-obaidi, Bassam Tashtoush & Stavros Malamataris. (2016) Sustained release of diltiazem HCl tableted after co-spray drying and physical mixing with PVAc and PVP. Drug Development and Industrial Pharmacy 42:2, pages 270-279.
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Chen Chen, Xiabing Xie, Yang Li, Chen Zhou, Yang Song, Zhixiang Yan & Xinghao Yang. (2014) Influence of different polymers on crystallization tendency and dissolution behavior of cilnidipine in solid dispersions. Drug Development and Industrial Pharmacy 40:4, pages 441-451.
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Dong-Jin Jang, Taeyong Sim & Euichaul Oh. (2013) Formulation and optimization of spray-dried amlodipine solid dispersion for enhanced oral absorption. Drug Development and Industrial Pharmacy 39:7, pages 1133-1141.
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Marc Hugo, Klaus Kunath & Jennifer Dressman. (2013) Selection of excipient, solvent and packaging to optimize the performance of spray-dried formulations: case example fenofibrate. Drug Development and Industrial Pharmacy 39:2, pages 402-412.
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Mohd Aftab Alam, Raisuddin Ali, Fahad Ibrahim Al-Jenoobi & Abdullah M Al-Mohizea. (2012) Solid dispersions: a strategy for poorly aqueous soluble drugs and technology updates. Expert Opinion on Drug Delivery 9:11, pages 1419-1440.
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Christina A. Lamey, Nermine Moussa, Maged W. Helmy, Medhat Haroun & Sally A. Sabra. (2023) Simultaneous encapsulation of dasatinib and celecoxib into caseinate micelles towards improved in vivo anti-breast cancer efficacy with reduced drug toxicity. Journal of Drug Delivery Science and Technology 87, pages 104807.
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Shubhajit Paul, Yiwang Guo, Chenguang Wang, Jiangnan Dun & Changquan Calvin Sun. (2023) Enabling direct compression tablet formulation of celecoxib by simultaneously eliminating punch sticking, improving manufacturability, and enhancing dissolution through co-processing with a mesoporous carrier. International Journal of Pharmaceutics 641, pages 123041.
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Tahereh Amini, Ali Haghtalab & Jaber Yousefi Seyf. (2023) Celecoxib solubility in two choline chloride-based deep eutectic solvents- Experimental study, thermodynamic modeling, and molecular dynamic simulation. Fluid Phase Equilibria 568, pages 113761.
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Susumu Suwabe, Tatsuaki Tagami, Koki Ogawa & Tetsuya Ozeki. (2023) Improved drug transfer into brain tissue via the “nose-to-brain” approach using suspension or powder formulations based on the amorphous solid dispersion technique. European Journal of Pharmaceutics and Biopharmaceutics 185, pages 137-147.
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Dominic Lucas, Jan Kožák, Annika Rautenberg, Claire Chrétien, Yann Pellequer & Alf Lamprecht. (2022) Designing highly porous amorphous celecoxib particles by spray freeze drying leads to accelerated drug absorption in-vivo. European Journal of Pharmaceutics and Biopharmaceutics 174, pages 20-28.
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Fatemeh Sadeghi, Zina Soleimanian, Farzin Hadizadeh, Azadeh Shirafkan, Hossein Kamali & Hadi Afrasiabi Garekani. (2022) Anti-solvent crystallization of celecoxib in the presence of PVP for enhancing the dissolution rate: Comparison of water and supercritical CO2 as two antisolvents. Chemical Engineering Research and Design 177, pages 741-750.
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Ali Fattahzadeh, Azin Jahangiri, Naser Ranjkeshzadeh & Faranak Ghaderi. (2021) Evaluation of Celecoxib-Lactose Incompatibility Reactions at Solid State using Physicochemical Methods. Journal of Research in Applied and Basic Medical Sciences 7:3, pages 139-146.
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Ali M. Nasr, Sameh S. Elhady, Shady A. Swidan & Noha M. Badawi. (2020) Celecoxib Loaded In-Situ Provesicular Powder and Its In-Vitro Cytotoxic Effect for Cancer Therapy: Fabrication, Characterization, Optimization and Pharmacokinetic Evaluation. Pharmaceutics 12:12, pages 1157.
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Rania Hamed & Haitham Omran. (2020) Development of dual–release pellets of the non-steroidal anti–inflammatory drug celecoxib. Journal of Drug Delivery Science and Technology 55, pages 101419.
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Vivek Puri, Manju Nagpal, Ameya Sharma, Gurjeet Singh Thakur, Manjinder Singh & Geeta Aggarwal. (2019) Development of binary dispersions and nanocomposites of irbesartan with enhanced antihypertensive activity. BioImpacts 10:4, pages 269-278.
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Mohammad A. Altamimi & Steven H. Neau. (2018) A study to identify the contribution of Soluplus® component homopolymers to the solubilization of nifedipine and sulfamethoxazole using the melting point depression method. Powder Technology 338, pages 576-585.
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Saeed Motallae, Azade Taheri & Alireza Homayouni. (2018) Preparation and characterization of solid dispersions of celecoxib obtained by spray-drying ethanolic suspensions containing PVP-K30 or isomalt. Journal of Drug Delivery Science and Technology 46, pages 188-196.
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Su Hyun Seok, Su-A. Lee & Eun-Seok Park. (2018) Formulation of a microemulsion-based hydrogel containing celecoxib. Journal of Drug Delivery Science and Technology 43, pages 409-414.
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Rana M. Obaidat, Bashar AlTaani & Anoud Ailabouni. (2017) Effect of different polymeric dispersions on In-vitro dissolution rate and stability of celecoxib class II drug. Journal of Polymer Research 24:4.
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Roya Ghanavati, Azade Taheri & Alireza Homayouni. (2017) Anomalous dissolution behavior of celecoxib in PVP/Isomalt solid dispersions prepared using spray drier. Materials Science and Engineering: C 72, pages 501-511.
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Mohammad A. Altamimi & Steven H. Neau. (2017) Investigation of the in vitro performance difference of drug-Soluplus® and drug-PEG 6000 dispersions when prepared using spray drying or lyophilization. Saudi Pharmaceutical Journal 25:3, pages 419-439.
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W. Grymonpré, G. Verstraete, P.J. Van Bockstal, J. Van Renterghem, P. Rombouts, T. De Beer, J.P. Remon & C. Vervaet. (2017) In-line monitoring of compaction properties on a rotary tablet press during tablet manufacturing of hot-melt extruded amorphous solid dispersions. International Journal of Pharmaceutics 517:1-2, pages 348-358.
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Maryam Maghsoodi & Ali Nokhodchi. (2016) Agglomeration of Celecoxib by Quasi Emulsion Solvent Diffusion Method: Effect of Stabilizer. Advanced Pharmaceutical Bulletin 6:4, pages 607-616.
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Hien Van Nguyen, Chulhun Park, Euichaul Oh & Beom-Jin Lee. (2016) Improving the dissolution rate of a poorly water-soluble drug via adsorption onto pharmaceutical diluents. Journal of Drug Delivery Science and Technology 35, pages 146-154.
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Abhishek Singh & Guy Van den Mooter. (2016) Spray drying formulation of amorphous solid dispersions. Advanced Drug Delivery Reviews 100, pages 27-50.
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Francesca Maestrelli, Marco Bragagni & Paola Mura. (2016) Advanced formulations for improving therapies with anti-inflammatory or anaesthetic drugs: A review. Journal of Drug Delivery Science and Technology 32, pages 192-205.
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Sophia Yui Kau Fong, Susana M. Martins, Martin Brandl & Annette Bauer-Brandl. (2016) Solid Phospholipid Dispersions for Oral Delivery of Poorly Soluble Drugs: Investigation Into Celecoxib Incorporation and Solubility-In Vitro Permeability Enhancement. Journal of Pharmaceutical Sciences 105:3, pages 1113-1123.
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W. De Jaeghere, T. De Beer, J. Van Bocxlaer, J.P. Remon & C. Vervaet. (2015) Hot-melt extrusion of polyvinyl alcohol for oral immediate release applications. International Journal of Pharmaceutics 492:1-2, pages 1-9.
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Alireza Homayouni, Fatemeh Sadeghi, Jaleh Varshosaz, Hadi Afrasiabi Garekani & Ali Nokhodchi. (2014) Promising dissolution enhancement effect of soluplus on crystallized celecoxib obtained through antisolvent precipitation and high pressure homogenization techniques. Colloids and Surfaces B: Biointerfaces 122, pages 591-600.
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Alireza Homayouni, Fatemeh Sadeghi, Jaleh Varshosaz, Hadi Afrasiabi Garekani & Ali Nokhodchi. (2014) Comparing various techniques to produce micro/nanoparticles for enhancing the dissolution of celecoxib containing PVP. European Journal of Pharmaceutics and Biopharmaceutics 88:1, pages 261-274.
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Hyeseung Lee & Jonghwi Lee. (2013) Dissolution enhancement of celecoxib via polymer-induced crystallization. Journal of Crystal Growth 374, pages 37-42.
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Paul Nkansah, Amy Antipas, Ying Lu, Manthena Varma, Charles Rotter, Brian Rago, Ayman El-Kattan, Graeme Taylor, Mario Rubio & John Litchfield. (2013) Development and evaluation of novel solid nanodispersion system for oral delivery of poorly water-soluble drugs. Journal of Controlled Release 169:1-2, pages 150-161.
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