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Drug Development and Industrial Pharmacy Volume 38, 2012 - Issue 8
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Research Article

Oral liquid in situ gelling methylcellulose/alginate formulations for sustained drug delivery to dysphagic patients

Tetsuya ShimoyamaFaculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan
,
Kunihiko ItohFaculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, JapanCorrespondence[email protected]
,
Michiya KobayashiFaculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan
,
Shozo MiyazakiFaculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan
,
Antony D’EmanueleSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, UK
&
David AttwoodSchool of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, UK
Pages 952-960 | Received 23 Mar 2011, Accepted 17 Oct 2011, Published online: 27 Jan 2012

Citations (13)

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Soha M. El-masry, Heba M. ElBedaiwy, Mohammad M. Abd-Alhaseeb, Mohamed S. Abdel-Maksoud & Doaa A. Habib. (2023) Green polymer altered in-situ gel oral liquid sustainable release preparation of vildagliptin suitable for dysphagic diabetic patients: assessment in-vitro & in-vivo. Pharmaceutical Development and Technology 28:7, pages 585-594.
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Samar M. Abouelatta, Ahmed A. Aboelwafa & Omaima N. El-Gazayerly. (2018) Gastroretentive raft liquid delivery system as a new approach to release extension for carrier-mediated drug. Drug Delivery 25:1, pages 1161-1174.
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Yoshiaki Shirata, Asami Wakasa, Kiyoshi Miura, Hironori Nakamura, Yoshinobu Matsumoto & Tomihiro Miyada. (2017) Body heat responsive gelation of methylcellulose formulation containing betaine. Bioscience, Biotechnology, and Biochemistry 81:9, pages 1829-1836.
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Hairui Li, Yuan Yu, Sara Faraji Dana, Bo Li, Chi-Ying Lee & Lifeng Kang. (2013) Novel engineered systems for oral, mucosal and transdermal drug delivery. Journal of Drug Targeting 21:7, pages 611-629.
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Articles from other publishers (9)

Kavil Patel & Fang Liu. 2023. Pharmaceutical Formulations for Older Patients. Pharmaceutical Formulations for Older Patients 129 155 .
Satoshi Nogami, Kazunori Kadota, Hiromasa Uchiyama, Hiroshi Arima-Osonoi, Mitsuhiro Shibayama & Yuichi Tozuka. (2022) Evaluation of the rheological and rupture properties of gelatin-based hydrogels blended with polymers to determine their drug diffusion behavior. Polymer Journal 54:12, pages 1477-1487.
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Sreejan Manna, Sougata Jana, Dipika Mandal & Manas Bhowmik. 2022. Marine Biomaterials. Marine Biomaterials 139 155 .
Lorenzo BonettiLuigi De NardoSilvia Farè. (2021) Thermo-Responsive Methylcellulose Hydrogels: From Design to Applications as Smart Biomaterials. Tissue Engineering Part B: Reviews 27:5, pages 486-513.
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Ebtessam A. Essa, Toka T. Elebyary, Magdy M. Abdelquader, Gamal M. El Maghraby & Amal A. Elkordy. (2021) Smart liquids for oral controlled drug release: An overview of alginate and non-alginate based systems. Journal of Drug Delivery Science and Technology 61, pages 102211.
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Manasa Moganti & H.N. Shivakumar. (2021) Oral raft forming in situ gelling system for site specific delivery of calcium. Journal of Drug Delivery Science and Technology 61, pages 102113.
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Nadia M. Morsi, Rehab Nabil Shamma, Nouran Osama Eladawy & Abdelfattah A. Abdelkhalek. (2019) RETRACTED ARTICLE: Risedronate-Loaded Macroporous Gel Foam Enriched with Nanohydroxyapatite: Preparation, Characterization, and Osteogenic Activity Evaluation Using Saos-2 Cells. AAPS PharmSciTech 20:3.
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Moayad KhalafRobin Augustine, Bhavana Venugopal, S Snigdha, Nandakumar Kalarikkal & Sabu Thomas. 2015. Green Polymers and Environmental Pollution Control. Green Polymers and Environmental Pollution Control 239 269 .
Tetsuya Shimoyama, Yuriko Miyagi, Kunihiko Itoh & Michiya Kobayashi. (2013) Effect of Storage Temperature on Gelation of Oral Methylcellulose Formulation経口メチルセルロース液剤のゲル化に及ぼす保存温度の影響. YAKUGAKU ZASSHI 133:6, pages 719-725.
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