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Drug Development and Industrial Pharmacy Volume 38, 2012 - Issue 12
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Research Article

To evaluate the effect of various magnesium stearate polymorphs using powder rheology and thermal analysis

Patrick OkoyeDivision of Pharmaceutical Sciences, Long Island University, Brooklyn, NY, USA
,
Stephen H. WuResearch & Development Center, Covidien, Webster Groves, MO, USA
&
Rutesh H. DaveDivision of Pharmaceutical Sciences, Long Island University, Brooklyn, NY, USACorrespondence[email protected]
Pages 1470-1478 | Received 11 Jul 2011, Accepted 26 Dec 2011, Published online: 05 Feb 2012

Citations (13)

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Read on this site (2)

Komlan Koumbogle, Ryan Gosselin, François Gitzhofer & Nicolas Abatzoglou. (2023) Effects of tableting process parameters and powder lubrication levels on tablet surface temperature and moisture content. Pharmaceutical Development and Technology 0:0, pages 1-8.
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Smruti P. Chaudhari & Rutesh H. Dave. (2015) To prepare and characterize microcrystalline cellulose granules using water and isopropyl alcohol as granulating agents and determine its end-point by thermal and rheological tools. Drug Development and Industrial Pharmacy 41:5, pages 744-752.
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Articles from other publishers (11)

Natalia Veronica, Yi Ying Loh, Lydia Xiu Ying Loh, Paul Wan Sia Heng & Celine Valeria Liew. (2023) Impact of magnesium stearate physical and chemical variabilities on pharmaceutical powder flow and tablet physical properties. Journal of Pharmaceutical Investigation.
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Lizbeth Martínez-Acevedo, Moises Job Galindo-Pérez, Gustavo Vidal-Romero, Alicia del Real, María de la Luz Zambrano-Zaragoza & David Quintanar-Guerrero. (2023) Effect of magnesium stearate solid lipid nanoparticles as a lubricant on the properties of tablets by direct compression. European Journal of Pharmaceutics and Biopharmaceutics 193, pages 262-273.
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Daniel Puckhaber, Arno Kwade & Jan Henrik Finke. (2023) Investigation of Dispersion Kinetics of Particulate Lubricants and their Effect on the Mechanical Strength of MCC Tablets. Pharmaceutical Research 40:10, pages 2479-2492.
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Mikkel Herzberg, Toms Rekis, Anders Støttrup Larsen, Ana Gonzalez, Jukka Rantanen & Anders Østergaard Madsen. (2023) The structure of magnesium stearate trihydrate determined from a micrometre-sized single crystal using a microfocused synchrotron X-ray beam. Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials 79:4, pages 330-335.
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Ji Yeon Kim & Du Hyung Choi. (2022) Quality by design approach with multivariate analysis and artificial neural network models to understand and control excipient variability. Journal of Pharmaceutical Investigation 53:3, pages 389-406.
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Naseem Ahmad Charoo. (2019) Critical Excipient Attributes Relevant to Solid Dosage Formulation Manufacturing. Journal of Pharmaceutical Innovation 15:1, pages 163-181.
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Rahul V. Haware, Bhavani Prasad Vinjamuri, Amrita Sarkar, Morgan Stefik & William C. Stagner. (2018) Deciphering magnesium stearate thermotropic behavior. International Journal of Pharmaceutics 548:1, pages 314-324.
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Sean P. Delaney, Matthew J. Nethercott, Christopher J. Mays, Nickolas T. Winquist, Donia Arthur, Julie L. Calahan, Manish Sethi, Daniel S. Pardue, Junghyun Kim, Gregory Amidon & Eric J. Munson. (2017) Characterization of Synthesized and Commercial Forms of Magnesium Stearate Using Differential Scanning Calorimetry, Thermogravimetric Analysis, Powder X-Ray Diffraction, and Solid-State NMR Spectroscopy. Journal of Pharmaceutical Sciences 106:1, pages 338-347.
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Ajit S. Narang, Lydia Breckenridge, Hang Guo, Jennifer Wang, Abraham (Avi) Wolf, Divyakant Desai, Sailesh Varia & Sherif Badawy. (2017) Assessment of Tablet Surface Hardness by Laser Ablation and Its Correlation With the Erosion Tendency of Core Tablets. Journal of Pharmaceutical Sciences 106:1, pages 200-207.
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Rahul V. Haware, Vivek S. Dave, Bhavyasri Kakarala, Sean Delaney, Scott Staton, Eric Munson, Mali Ram Gupta & William C. Stagner. (2016) Vegetable-derived magnesium stearate functionality evaluation by DM3 approach. European Journal of Pharmaceutical Sciences 89, pages 115-124.
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Jinjiang Li & Yongmei Wu. (2014) Lubricants in Pharmaceutical Solid Dosage Forms. Lubricants 2:1, pages 21-43.
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