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Research Article

Bioavailability enhancement of baclofen by gastroretentive floating formulation: statistical optimization, in vitro and in vivo pharmacokinetic studies

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Pages 880-888 | Received 12 Dec 2011, Accepted 30 Jun 2012, Published online: 20 Aug 2012

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Read on this site (6)

Krutika K. Sawant, Mitali H. Patel & Krishna Patel. (2016) Cefdinir nanosuspension for improved oral bioavailability by media milling technique: formulation, characterization and in vitro–in vivo evaluations. Drug Development and Industrial Pharmacy 42:5, pages 758-768.
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Yanhua Liu, Lihong Chen, Chengming Zhou, Jianhong Yang, Yanhui Hou & Wenping Wang. (2016) Development and evaluation of alginate-chitosan gastric floating beads loading with oxymatrine solid dispersion. Drug Development and Industrial Pharmacy 42:3, pages 456-463.
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Alessandra Rossi, Chiara Conti, Gaia Colombo, Luca Castrati, Carmelo Scarpignato, Pedro Barata, Giuseppina Sandri, Carla Caramella, Ruggero Bettini, Francesca Buttini & Paolo Colombo. (2016) Floating modular drug delivery systems with buoyancy independent of release mechanisms to sustain amoxicillin and clarithromycin intra-gastric concentrations. Drug Development and Industrial Pharmacy 42:2, pages 332-339.
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Yunyun Gao, Yang Gao, Fei Yin, Mi Wang, Zhenhong Wang, Tiantian Ye, Yonggang Yang, W. S. Pan & Xinggang Yang. (2015) Preparation and pharmacokinetics study on gastro-floating sustained-release tablets of troxipide. Drug Development and Industrial Pharmacy 41:9, pages 1443-1451.
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Huiming Jiang, Rui Tian, Wenjing Hu, Yuntao Jia, Pei Yuan, Jiayu Wang & Liangke Zhang. (2015) Formulation and evaluation of gastroretentive floating drug delivery system of dipyridamole. Drug Development and Industrial Pharmacy 41:4, pages 674-680.
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Abdul Raheman Abdul Razzaque Solanki, Avesh Iliyas Sumar, Prof. Naved Khan & Dr. Nitin B. Kohale. (2023) Immediate Release Drug Dosage Form. International Journal of Advanced Research in Science, Communication and Technology, pages 276-284.
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Kiran Shetty & Hetal Thakkar. (2023) Development of Paediatric Formulation of Baclofen for Improved Safety and Palatability. Journal of Pharmaceutical Innovation.
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Bhumika Mangla & Deepinder Singh Malik. (2022) Polymeric approach for formulating sustained release floating tablets of domperidone: An in-vivo investigation. Materials Today: Proceedings.
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Manoj A. Pawar, Ganesh B. Shevalkar & Pradeep R. Vavia. (2022) Design and Development of Gastro-retentive Drug Delivery System for Trazodone Hydrochloride: a Promising Alternative to Innovator’s Controlled-Release Tablet. AAPS PharmSciTech 23:7.
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Jamal Moideen Muthu Mohamed, Nikita Mahajan, Mohamed El-Sherbiny, Shagufta Khan, Rasha Hamed Al-Serwi, Mohammed A. Attia, Qamar Alsayed Altriny & Ahmed H. Arbab. (2022) Ameliorated Stomach Specific Floating Microspheres for Emerging Health Pathologies Using Polymeric Konjac Glucomannan-Based Domperidone. BioMed Research International 2022, pages 1-12.
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Pradipkumar Wavhule & Padma V. Devarajan. (2021) Development and Optimization of Microballoons Assisted Floating Tablets of Baclofen. AAPS PharmSciTech 22:8.
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Supratim Das, Sukhbir Kaur & Vineet Kumar Rai. (2021) Gastro-retentive drug delivery systems: a recent update on clinical pertinence and drug delivery. Drug Delivery and Translational Research 11:5, pages 1849-1877.
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Mohamed Ibrahim, Youssef W. Naguib, Hatem A. Sarhan & Hamdy Abdelkader. (2021) Preformulation-Assisted Design and Characterization of Modified Release Gastroretentive Floating Extrudates Towards Improved Bioavailability and Minimized Side Effects of Baclofen. Journal of Pharmaceutical Sciences 110:3, pages 1227-1239.
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Nieves Iglesias, Elsa Galbis, Lucía Romero-Azogil, Elena Benito, Ricardo Lucas, M. Gracia García-Martín & M.-Violante de-Paz. (2020) In-Depth Study into Polymeric Materials in Low-Density Gastroretentive Formulations. Pharmaceutics 12:7, pages 636.
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Hyeon Myeong Jeong, Kwon-Yeon Weon, Beom Soo Shin & Soyoung Shin. (2020) 3D-Printed Gastroretentive Sustained Release Drug Delivery System by Applying Design of Experiment Approach. Molecules 25:10, pages 2330.
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Mohamed Ibrahim, Hatem A. Sarhan, Youssef W. Naguib & Hamdy Abdelkader. (2020) Design, characterization and in vivo evaluation of modified release baclofen floating coated beads. International Journal of Pharmaceutics 582, pages 119344.
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Tamalika Bhakat, Aniruddha Roy, Ajay Agarwal, Niti Nipun Sharma & Sachin U. Belgamwar. (2019) Bio-hydrogel for Prolonged Controlled Gastro-retentive Drug Dispenser. Bio-hydrogel for Prolonged Controlled Gastro-retentive Drug Dispenser.
Kuldeep Singh, Subheet K. Jain, Karan Razdan, Harmanpreet Singh, Nikhil S. Sahajpal, Harjeet Singh, Amrinder Singh & Shubham Thakur. (2019) Formulation and Evaluation of Ferrous Ascorbate Floating Tablets for the Treatment of Anaemia. Drug Delivery Letters 9:4, pages 299-307.
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Alison Hayward, Taylor Bensel, Hormoz Mazdiyasni, Jaimie Rogner, Ameya R. Kirtane, Young-Ah Lucy Lee, Tiffany Hua, Ambika Bajpayee, Joy Collins, Shane McDonnell, Cody Cleveland, Aaron Lopes, Aniket Wahane, Robert Langer & Giovanni Traverso. (2018) Scalable Gastric Resident Systems for Veterinary Application. Scientific Reports 8:1.
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Behzad Darbasizadeh, Hamidreza Motasadizadeh, Behrouz Foroughi-Nia & Hassan Farhadnejad. (2018) Tripolyphosphate-crosslinked chitosan/poly (ethylene oxide) electrospun nanofibrous mats as a floating gastro-retentive delivery system for ranitidine hydrochloride. Journal of Pharmaceutical and Biomedical Analysis 153, pages 63-75.
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Jung-Myung Ha, Jeong-Woong Seo, Su-Hyeon Kim, Ju-Young Kim, Chun-Woong Park, Yun-Seok Rhee & Eun-Seok Park. (2017) Implementation of Quality by Design for Formulation of Rebamipide Gastro-retentive Tablet. AAPS PharmSciTech 18:8, pages 3129-3139.
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Radhakrishnan Praveen, Priya Ranjan Prasad Verma, Jayachandran Venkatesan, Dong-Han Yoon, Se-Kwon Kim & Sandeep Kumar Singh. (2017) In vitro and in vivo evaluation of gastro-retentive carvedilol loaded chitosan beads using Gastroplus™. International Journal of Biological Macromolecules 102, pages 642-650.
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Erin Stewart & Laura M. Tormoehlen. 2017. Critical Care Toxicology. Critical Care Toxicology 1119 1131 .
Uttam Kumar Mandal, Bappaditya Chatterjee & Faria Gias Senjoti. (2016) Gastro-retentive drug delivery systems and their in vivo success: A recent update. Asian Journal of Pharmaceutical Sciences 11:5, pages 575-584.
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Erin Stewart & Laura M. Tormoehlen. 2016. Critical Care Toxicology. Critical Care Toxicology 1 14 .

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