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Research Article

Production of extended release mini-tablets using directly compressible grades of HPMC

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Pages 1690-1697 | Received 16 Apr 2012, Accepted 11 Sep 2012, Published online: 19 Oct 2012

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Read on this site (3)

Faiezah A. A. Mohamed, Matthew Roberts, Linda Seton, James L. Ford, Marina Levina & Ali R. Rajabi-Siahboomi. (2015) Film-coated matrix mini-tablets for the extended release of a water-soluble drug. Drug Development and Industrial Pharmacy 41:4, pages 623-630.
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Faiezah A. A. Mohamed, Matthew Roberts, Linda Seton, James L. Ford, Marina Levina & Ali R. Rajabi-Siahboomi. (2015) The effect of HPMC particle size on the drug release rate and the percolation threshold in extended-release mini-tablets. Drug Development and Industrial Pharmacy 41:1, pages 70-78.
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Aleksandar Aleksovski, Rok Dreu, Mirjana Gašperlin & Odon Planinšek. (2015) Mini-tablets: a contemporary system for oral drug delivery in targeted patient groups. Expert Opinion on Drug Delivery 12:1, pages 65-84.
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Articles from other publishers (13)

Arkadiusz Hejduk & Janina Lulek. (2022) Dispensing of minitablets – Has the problem been resolved?. International Journal of Pharmaceutics 619, pages 121666.
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Nihad Mawla, Sarah Hanley, Karl Walton, Waseem Kaialy, Tariq Hussain, Adam Ward, Jonathan Brown, Barbara R. Conway, Peter Timmins & Kofi Asare-Addo. (2020) Imaging of the Effect of Alcohol-Containing Media on the Performance of Hypromellose Hydrophilic Matrix Tablets: Comparison of Direct Compression and Regular Grades of Polymer. Pharmaceutics 12:9, pages 889.
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Chen Luo, Yun Huang, Zhengli Yin, Hao Xu, Xiaolong Qin, Xing Li, Mingshan Wang & Yuanhua Lin. (2020) A universal natural hydroxy propyl methyl cellulose polymer additive for modifying lignocellulose-based gel polymer electrolytes and stabilizing lithium metal anodes. Materials Chemistry and Physics 250, pages 123174.
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Hesham M. Tawfeek, Matthew Roberts, Mohamed A. El Hamd, Ahmed A. H. Abdellatif & Mahmoud A. Younis. (2018) Glibenclamide Mini-tablets with an Enhanced Pharmacokinetic and Pharmacodynamic Performance. AAPS PharmSciTech 19:7, pages 2948-2960.
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Junshu Zhao, David Yin, Jasmine Rowe, Sherif Badawy, Faranak Nikfar & Preetanshu Pandey. (2018) Understanding the Factors That Control the Quality of Mini-Tablet Compression: Flow, Particle Size, and Tooling Dimension. Journal of Pharmaceutical Sciences 107:4, pages 1204-1208.
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Jude Madathilethu, Matthew Roberts, Matthew Peak, Joanne Blair, Rebecca Prescott & James L Ford. (2018) Content uniformity of quartered hydrocortisone tablets in comparison with mini-tablets for paediatric dosing. BMJ Paediatrics Open 2:1, pages e000198.
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Ugurlu Timucin. (2017) Mini Tablets: A Short Review-Revision. Open Journal of Chemistry, pages 012-022.
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Marina Levina, Hue Voung & Ali R. Rajabi-Siahboomi. 2017. Multiparticulate Drug Delivery. Multiparticulate Drug Delivery 95 118 .
Satu Lakio, Pirjo Tajarobi, Håkan Wikström, Magnus Fransson, Johan Arnehed, Tuomas Ervasti, Simo-Pekka Simonaho, Jarkko Ketolainen, Staffan Folestad & Susanna Abrahmsén-Alami. (2016) Achieving a robust drug release from extended release tablets using an integrated continuous mixing and direct compression line. International Journal of Pharmaceutics 511:1, pages 659-668.
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Martin Kuentz, René Holm & David P. Elder. (2016) Methodology of oral formulation selection in the pharmaceutical industry. European Journal of Pharmaceutical Sciences 87, pages 136-163.
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Yoshiyuki Hayakawa, Shinya Uchida & Noriyuki Namiki. (2016) Evaluation of the ease of taking mini-tablets compared with other tablet formulations in healthy volunteers. European Journal of Pharmaceutical Sciences 84, pages 157-161.
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Tuomas Ervasti, Simo-Pekka Simonaho, Jarkko Ketolainen, Peter Forsberg, Magnus Fransson, Håkan Wikström, Staffan Folestad, Satu Lakio, Pirjo Tajarobi & Susanna Abrahmsén-Alami. (2015) Continuous manufacturing of extended release tablets via powder mixing and direct compression. International Journal of Pharmaceutics 495:1, pages 290-301.
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Aleksandar Aleksovski, Matevž Luštrik, Rok Šibanc & Rok Dreu. (2015) Design and evaluation of a specific, bi-phase extended release system based on differently coated mini-tablets. European Journal of Pharmaceutical Sciences 75, pages 114-122.
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