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Research Article

Design and development of multiple emulsion for enhancement of oral bioavailability of acyclovir

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Pages 1809-1817 | Received 21 Jun 2012, Accepted 05 Oct 2012, Published online: 02 Jan 2013

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Naima Faghmous, Djallel Bouzid, Marwa Boumaza, Asma Touati & Olivier Boyron. (2021) Optimization of chitosan-coated W/O/W multiple emulsion stabilized with Span 80 and Tween 80 using Box–Behnken design. Journal of Dispersion Science and Technology 42:10, pages 1566-1578.
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Mona G. Sakr, Sally A. El-Zahaby, Abdulaziz M. Al-Mahallawi & Dalia M. Ghorab. (2023) A novel reverse micelle based cationic double nanoemulsion as a potential nanoplatform for enhancing the anitglucomal activity of betaxolol hydrochloride; formulation, in vitro characterization, ex vivo permeation and in vivo pharmacodynamic evaluation in glaucomatous rabbits’ eyes. Journal of Drug Delivery Science and Technology 90, pages 105112.
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Soyoung Shin, Tae Hwan Kim, Seok Won Jeong, Seung Eun Chung, Da Young Lee, Do-Hyung Kim & Beom Soo Shin. (2019) Development of a gastroretentive delivery system for acyclovir by 3D printing technology and its in vivo pharmacokinetic evaluation in Beagle dogs. PLOS ONE 14:5, pages e0216875.
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Jelena Mudrić, Katarina Šavikin, Svetlana Ibrić & Jelena Đuriš. (2019) Double emulsions (W/O/W emulsions): Encapsulation of plant bioactives. Lekovite sirovine:39, pages 76-83.
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Lidong Han, Rong Yang, Shengxiao Yuan, Shuang Ding, Ziheng Wu, Zhenghong Wu & Xiaole Qi. (2018) Soft multiple emulsions demonstrating reversible freeze-thawing capacity and enhanced skin permeability of diclofenac sodium. Colloid and Polymer Science 296:3, pages 471-481.
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Yanqing Song, Huan Gao, Sixi Zhang, Yue Zhang, Xiangqun Jin & Jingmeng Sun. (2017) Prescription Optimization and Oral Bioavailability Study of Salvianolic Acid Extracts W/O/W Multiple Emulsion. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 40:12, pages 2081-2087.
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Haniza Hassan, Siti Khadijah Adam, Fauziah Othman, Ahmad Fuad Shamsuddin & Rusliza Basir. (2016) Antiviral Nanodelivery Systems: Current Trends in Acyclovir Administration. Journal of Nanomaterials 2016, pages 1-8.
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Bandar E. Al-Dhubiab, Anroop B. Nair, Rachna Kumria, Mahesh Attimarad & Sree Harsha. (2015) Formulation and evaluation of nano based drug delivery system for the buccal delivery of acyclovir. Colloids and Surfaces B: Biointerfaces 136, pages 878-884.
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Magnus N. Hattrem, Kåre A. Kristiansen, Finn L. Aachmann, Morten J. Dille & Kurt I. Draget. (2015) Ibuprofen-in-cyclodextrin-in-W/O/W emulsion – Improving the initial and long-term encapsulation efficiency of a model active ingredient. International Journal of Pharmaceutics 487:1-2, pages 1-7.
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Iris J. Joye, Gabriel Davidov-Pardo & David Julian McClements. (2014) Nanotechnology for increased micronutrient bioavailability. Trends in Food Science & Technology 40:2, pages 168-182.
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P.L. Lam & R. Gambari. (2014) Advanced progress of microencapsulation technologies: In vivo and in vitro models for studying oral and transdermal drug deliveries. Journal of Controlled Release 178, pages 25-45.
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