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Drug Development and Industrial Pharmacy Volume 40, 2014 - Issue 2
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Research Article

Investigation of the mechanisms of improved oral bioavailability of bergenin using bergenin–phospholipid complex

Shan GuanKey Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education, West China School of Pharmacy, Sichuan University ChengduPR China
,
Xuan QinKey Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education, West China School of Pharmacy, Sichuan University ChengduPR China
,
Zhou ZhouKey Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education, West China School of Pharmacy, Sichuan University ChengduPR China
,
Qiang ZhangState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University BeijingPR China
&
Yuan HuangKey Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education, West China School of Pharmacy, Sichuan University ChengduPR ChinaCorrespondence[email protected]
Pages 163-171 | Received 06 Sep 2012, Accepted 14 Nov 2012, Published online: 15 Jan 2013

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Rafael Henrique Holanda Pinto, Fernanda Wariss Figueiredo Bezerra, Priscila do Nascimento do Nascimento Bezerra & Raul Nunes de Carvalho Junior. (2023) Phytochemical Composition and Functional Potential of Uxi (Endopleura Uchi): An Overview. Food Reviews International 39:2, pages 787-801.
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Fei Li, Xiaolin Yang, Yanan Yang, Ping Li, Zhonglin Yang & Chunfeng Zhang. (2015) Phospholipid complex as an approach for bioavailability enhancement of echinacoside. Drug Development and Industrial Pharmacy 41:11, pages 1777-1784.
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Articles from other publishers (13)

Sidharth Mehta, Varsha Kadian, Sweta Dalal, Pooja Dalal, Sunil Kumar, Minakshi Garg & Rekha Rao. (2022) A Fresh Look on Bergenin: Vision of Its Novel Drug Delivery Systems and Pharmacological Activities. Future Pharmacology 2:1, pages 64-91.
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Pulok Kumar Mukherjee, Sayan Biswas, Amit Kar, Nanaocha Sharma & Pallab Kanti Haldar. 2022. Evidence-Based Validation of Herbal Medicine. Evidence-Based Validation of Herbal Medicine 65 108 .
Sandeep Kumar Singh, Mamunur Rashid, Kripal Bhalala, Yaseen Malik, Swati Chaturvedi, Kanumuri S.R. Raju, Nazneen Sultana, Kalyan Mitra, Jiaur R. Gayen & Muhammad Wahajuddin. (2021) A novel nanosized phospholipid complex of Biochanin A for improving oral bioavailability: Preparation and in-vitro/in-vivo characterizations. Journal of Drug Delivery Science and Technology 61, pages 102254.
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Mandeep, Shamandeep Kaur, Sanjaya K. Samal, Sabyasachi Roy & Abhay T. Sangamwar. (2020) Successful oral delivery of fexofenadine hydrochloride by improving permeability via phospholipid complexation. European Journal of Pharmaceutical Sciences 149, pages 105338.
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Hai-Qiu Ma, Chen-Qiang Zuo, Ye Yuan, Yu-Pu Zhang, Xue Wang, Shu-Yan Wang & Jun-Wei Liu. (2020) The UPLC-MS/MS Method for Determination of a Novel Enterovirus 71 Inhibitor in Rat Plasma and its Application to Pharmacokinetic Study. Current Pharmaceutical Analysis 16:2, pages 117-124.
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L.V.D. Freitas, A.C.R. Montes, E.I.A. Campos, E.C. Conceição, L.A. Tacon, A.D. Lanchote & L.A.P. Freitas. (2019) Rice spouted bed for manufacturing inclusion complexes of Endopleura uchi L extracts in β-cyclodextrin. Particuology 42, pages 208-215.
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Isabel Lozoya-Agullo, Isabel González-Álvarez, Matilde Merino-Sanjuán, Marival Bermejo & Marta González-Álvarez. (2018) Preclinical models for colonic absorption, application to controlled release formulation development. European Journal of Pharmaceutics and Biopharmaceutics 130, pages 247-259.
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Nicolas Gautschi, Peter Van Hoogevest & Martin Kuentz. (2017) Molecular insights into the formation of drug-monoacyl phosphatidylcholine solid dispersions for oral delivery. European Journal of Pharmaceutical Sciences 108, pages 93-100.
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Yiqiong Pu, Xitong Zhang, Qi Zhang, Bing Wang, Yuxi Chen, Chuanqi Zang, Yuqin Wang, Tina Dong & Tong Zhang. (2016) 20(S)-Protopanaxadiol Phospholipid Complex: Process Optimization, Characterization, In Vitro Dissolution and Molecular Docking Studies. Molecules 21:10, pages 1396.
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Faiyaz Shakeel, Mohamed F. AlAjmi, Nazrul Haq, Nasir A. Siddiqui, Perwez Alam & Adnan J. Al-Rehaily. (2016) Solubility and thermodynamic function of a bioactive compound bergenin in various pharmaceutically acceptable neat solvents at different temperatures. The Journal of Chemical Thermodynamics 101, pages 19-24.
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Faiyaz Shakeel, Ramzi A. Mothana, Nazrul Haq, Nasir A. Siddiqui, Mai M. Al-Oqail & Adnan J. Al-Rehaily. (2016) Solubility and thermodynamic function of bergenin in different (DMSO + water) mixtures at different temperatures. Journal of Molecular Liquids 220, pages 823-828.
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Nicolas Gautschi, Peter Van Hoogevest & Martin Kuentz. (2015) Amorphous drug dispersions with mono- and diacyl lecithin: On molecular categorization of their feasibility and UV dissolution imaging. International Journal of Pharmaceutics 491:1-2, pages 218-230.
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Abdalrahim FA Aisha, Amin Malik Shah Abdul Majid & Zhari Ismail. (2014) Preparation and characterization of nano liposomes of Orthosiphon stamineusethanolic extract in soybean phospholipids. BMC Biotechnology 14:1.
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