1,298
Views
98
CrossRef citations to date
0
Altmetric
Research Article

Formulation and characterization of intranasal mucoadhesive nanoparticulates and thermo-reversible gel of levodopa for brain delivery

, &
Pages 869-878 | Received 29 Jul 2012, Accepted 20 Mar 2013, Published online: 19 Apr 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

S. L. Neha, Ashwini Kumar Mishra, Laxmi Rani, Shweta Paroha, Hitesh Kumar Dewangan & Pravat Kumar Sahoo. (2023) Design and evaluations of a nanostructured lipid carrier loaded with dopamine hydrochloride for intranasal bypass drug delivery in Parkinson’s disease. Journal of Microencapsulation 40:8, pages 599-612.
Read now
S.L Neha, Ashwini Kumar Mishra, Laxmi Rani, Suraj Pal Verma & Pravat Kumar Sahoo. (2022) Characterization and HPLC Method Validation for Determination of Dopamine Hydrochloride in Prepared Nano Particles and Pharmacokinetic Application. Analytical Chemistry Letters 12:4, pages 528-541.
Read now
Piyong Sola, Praveen Krishnamurthy, Pavan Kumar Chintamaneni, Sai Kiran S.S Pindiprolu & Mamta Kumari. (2020) Novel drug delivery systems of β2 adrenoreceptor agonists to suppress SNCA gene expression and mitochondrial oxidative stress in Parkinson’s disease management. Expert Opinion on Drug Delivery 17:8, pages 1119-1132.
Read now
Sema Arisoy, Ozgun Sayiner, Tansel Comoglu, Deniz Onal, Ozbeyen Atalay & Bilge Pehlivanoglu. (2020) In vitro and in vivo evaluation of levodopa-loaded nanoparticles for nose to brain delivery. Pharmaceutical Development and Technology 25:6, pages 735-747.
Read now
Rahul P. Patil, Devlya D. Pawara, Chetan S. Gudewar & Avinash R. Tekade. (2019) Nanostructured cubosomes in an in situ nasal gel system: an alternative approach for the controlled delivery of donepezil HCl to brain. Journal of Liposome Research 29:3, pages 264-273.
Read now
Monica Rao, Deepak Kumar Agrawal & Chaitanya Shirsath. (2017) Thermoreversible mucoadhesive in situ nasal gel for treatment of Parkinson’s disease. Drug Development and Industrial Pharmacy 43:1, pages 142-150.
Read now
Shadab Md, Gulam Mustafa, Sanjula Baboota & Javed Ali. (2015) Nanoneurotherapeutics approach intended for direct nose to brain delivery. Drug Development and Industrial Pharmacy 41:12, pages 1922-1934.
Read now
Abhijeet D. Kulkarni, Yogesh H. Vanjari, Karan H. Sancheti, Veena S. Belgamwar, Sanjay J. Surana & Chandrakantsing V. Pardeshi. (2015) Nanotechnology-mediated nose to brain drug delivery for Parkinson's disease: a mini review. Journal of Drug Targeting 23:9, pages 775-788.
Read now
Prabhjot Kaur, Tarun Garg, Bhuvaneshwar Vaidya, Atish Prakash, Goutam Rath & Amit K. Goyal. (2015) Brain delivery of intranasal in situ gel of nanoparticulated polymeric carriers containing antidepressant drug: behavioral and biochemical assessment. Journal of Drug Targeting 23:3, pages 275-286.
Read now

Articles from other publishers (89)

Shampa Ghosh, Soumya Ghosh, Hitaishi Sharma, Rakesh Bhaskar, Sung Soo Han & Jitendra Kumar Sinha. (2024) Harnessing the power of biological macromolecules in hydrogels for controlled drug release in the central nervous system: A review. International Journal of Biological Macromolecules 254, pages 127708.
Crossref
Miao Wang, Xinyu Ma, Shiyu Zong, Yaqiong Su, Rui Su, Hong Zhang, Yang Liu, Chunliu Wang & Ye Li. (2024) The prescription design and key properties of nasal gel for CNS drug delivery: A review. European Journal of Pharmaceutical Sciences 192, pages 106623.
Crossref
Sumaia Abdulbari Ahmed Ali Hard, H.N. Shivakumar & Moqbel Ali Moqbel Redhwan. (2023) Development and optimization of in-situ gel containing chitosan nanoparticles for possible nose-to-brain delivery of vinpocetine. International Journal of Biological Macromolecules 253, pages 127217.
Crossref
Zhiren Wang, Karina Marie Gonzalez, Leyla Estrella Cordova & Jianqin Lu. (2023) Nanotechnology‐empowered therapeutics targeting neurodegenerative diseases. WIREs Nanomedicine and Nanobiotechnology 15:5.
Crossref
Xu Zhang, Maohua Wang, Zhixian Liu, Ying Wang, Li Chen, Jiaqi Guo, Wentao Zhang, Yao Zhang, Chenjie Yu, Tongwu Bie, Youjun Yu & Bing Guan. (2023) Transnasal-brain delivery of nanomedicines for neurodegenerative diseases. Frontiers in Drug Delivery 3.
Crossref
Youssef Ait Hamdan, Samia Elouali, Abdelali Ben Maloui, Bilal El-Mansoury, Hassane Oudadesse & Mohammed Rhazi. 2023. Experimental and Clinical Evidence of the Neuropathology of Parkinson’s Disease. Experimental and Clinical Evidence of the Neuropathology of Parkinson’s Disease 253 274 .
Emile F. van Vliet, Maarten J. Knol, Raymond M. Schiffelers, Massimiliano Caiazzo & Marcel H.A.M. Fens. (2023) Levodopa-loaded nanoparticles for the treatment of Parkinson's disease. Journal of Controlled Release 360, pages 212-224.
Crossref
Thuy Trang Nguyen, Phuong-Trang Nguyen-Thi, Thi Hong Anh Nguyen, Thanh-Tam Ho, Nguyen-Minh-An Tran, Toi Van Vo & Giau Van Vo. (2023) Recent Advancements in Nanomaterials: A Promising Way to Manage Neurodegenerative Disorders. Molecular Diagnosis & Therapy 27:4, pages 457-473.
Crossref
Paramita Saha, Himanshu Kathuria & Murali Monohar Pandey. (2023) Intranasal nanotherapeutics for brain targeting and clinical studies in Parkinson's disease. Journal of Controlled Release 358, pages 293-318.
Crossref
Dharmendra K. Khatri, Kumari Preeti, Shivraj Tonape, Sheoshree Bhattacharjee, Monica Patel, Saurabh Shah, Pankaj K. Singh, Saurabh Srivastava, Dalapathi Gugulothu, Lalitkumar Vora & Shashi B. Singh. (2023) Nanotechnological Advances for Nose to Brain Delivery of Therapeutics to Improve the Parkinson Therapy. Current Neuropharmacology 21:3, pages 493-516.
Crossref
Andrea Vaquero-Rodríguez, Jone Razquin, Maider Zubelzu, Raphaelle Bidgood, Harkaitz Bengoetxea, Cristina Miguelez, Teresa Morera-Herreras, Jose Angel Ruiz-Ortega, José Vicente Lafuente & Naiara Ortuzar. 2023. Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-Morbidity Factors Part B. Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-Morbidity Factors Part B 103 143 .
Urba Afnan, Mohamad Sultan Khan, C.A. Swaliha, Umar Manzoor, Ibtisam Mumtaz, Mohd Jamal Dar & Tariq Maqbool. 2023. Phospholipases in Physiology and Pathology. Phospholipases in Physiology and Pathology 129 157 .
Margarita E. Neganova, Yulia R. Aleksandrova, Olga A. Sukocheva & Sergey G. Klochkov. (2022) Benefits and limitations of nanomedicine treatment of brain cancers and age-dependent neurodegenerative disorders. Seminars in Cancer Biology 86, pages 805-833.
Crossref
Nicolò Montegiove, Eleonora Calzoni, Carla Emiliani & Alessio Cesaretti. (2022) Biopolymer Nanoparticles for Nose-to-Brain Drug Delivery: A New Promising Approach for the Treatment of Neurological Diseases. Journal of Functional Biomaterials 13:3, pages 125.
Crossref
Thuy Trang Nguyen, Nguyen Si Bao & Giau Van Vo. (2022) Advances in Hydrogel-Based Drug Delivery Systems for Parkinson's Disease. Neurochemical Research 47:8, pages 2129-2141.
Crossref
Shima Ourani-Pourdashti, Esmaeil Mirzaei, Reza Heidari, Hajar Ashrafi & Amir Azadi. (2022) Preparation and evaluation of niosomal chitosan-based in situ gel formulation for direct nose-to-brain methotrexate delivery. International Journal of Biological Macromolecules 213, pages 1115-1126.
Crossref
Xuan Liu, Shen Yan, Mengyuan Li, Shengyu Zhang, Gang Guo, Quanyi Yin, Zhenbo Tong, Xiao Dong Chen & Winston Duo Wu. (2022) Spray Dried Levodopa-Doped Powder Potentially for Intranasal Delivery. Pharmaceutics 14:7, pages 1384.
Crossref
Shuai Zha, Ka‐Leung Wong & Angelo H. All. (2022) Intranasal Delivery of Functionalized Polymeric Nanomaterials to the Brain. Advanced Healthcare Materials 11:11.
Crossref
Haidy Abbas, Nesrine S El Sayed, Nancy Abdel Hamid Abou Youssef, Passent M. E. Gaafar, Mohamed R. Mousa, Ahmed M. Fayez & Manal A Elsheikh. (2022) Novel Luteolin-Loaded Chitosan Decorated Nanoparticles for Brain-Targeting Delivery in a Sporadic Alzheimer’s Disease Mouse Model: Focus on Antioxidant, Anti-Inflammatory, and Amyloidogenic Pathways. Pharmaceutics 14:5, pages 1003.
Crossref
Hellen Windolf, Rebecca Chamberlain, Jörg Breitkreutz & Julian Quodbach. (2022) 3D Printed Mini-Floating-Polypill for Parkinson’s Disease: Combination of Levodopa, Benserazide, and Pramipexole in Various Dosing for Personalized Therapy. Pharmaceutics 14:5, pages 931.
Crossref
Shiv Kumar SrivastavaMahesh PrasadAntesh Kumar Jha. (2022) Development and Evaluation of Thermo Triggered in situ Nasal Gel of Selegiline for Depressive Disorders: In vitro, in vivo and ex vivo Characterization. Research Journal of Pharmacy and Technology, pages 1424-1430.
Crossref
Savvas Dimiou, Rui M. Lopes, Ilona Kubajewska, Ryan D. Mellor, Corinna S. Schlosser, Manjunath S. Shet, Hugh Huang, Ozgur Akcan, Garth T. Whiteside, Andreas G. Schätzlein & Ijeoma F. Uchegbu. (2022) Particulate levodopa nose-to-brain delivery targets dopamine to the brain with no plasma exposure. International Journal of Pharmaceutics 618, pages 121658.
Crossref
Xiangjie Di, Xiao Liang, Chao Shen, Yuwen Pei, Bin Wu & Zhiyao He. (2022) Carbohydrates Used in Polymeric Systems for Drug Delivery: From Structures to Applications. Pharmaceutics 14:4, pages 739.
Crossref
Mohd Zulhelmy Ahmad, Akmal Hidyat Bin Sabri, Qonita Kurnia Anjani, Juan Domínguez-Robles, Normala Abdul Latip & Khuriah Abdul Hamid. (2022) Design and Development of Levodopa Loaded Polymeric Nanoparticles for Intranasal Delivery. Pharmaceuticals 15:3, pages 370.
Crossref
Sumit Sharma, Sonali Batra, Saurabh Gupta, Vivek K. Sharma, Md. Habibur Rahman & Mohammad Amjad Kamal. (2022) Persons with Co-Existing Neurological Disorders: Risk Analysis, Considerations and Management in COVID-19 Pandemic. CNS & Neurological Disorders - Drug Targets 21:3, pages 228-234.
Crossref
Sreeranjini Sukumaran Rajamma, Venkateshwaran Krishnaswami, Sakthivel Lakshmana Prabu & Ruckmani Kandasamy. (2022) Geophila repens phytosome-loaded intranasal gel with improved nasal permeation for the effective treatment of Alzheimer's disease. Journal of Drug Delivery Science and Technology 69, pages 103087.
Crossref
Sema Arisoy & Tansel Comoglu. (2022) Effect of Formulation Variables for the Production of WGA-Grafted, Levodopa-Loaded PLGA Nanoparticles. Journal of Biomimetics, Biomaterials and Biomedical Engineering 54, pages 1-15.
Crossref
Chhavi Bhalothia & Girima Nagda. (2022) Nanotherapeutics a promising approach for treatment of Parkinson’s disease. Materials Today: Proceedings 69, pages A1-A13.
Crossref
Honey Goel, Vinni Kalra, Sant Kumar Verma, Sunil Kumar Dubey & Ashok Kumar Tiwary. (2022) Convolutions in the rendition of nose to brain therapeutics from bench to bedside: Feats & fallacies. Journal of Controlled Release 341, pages 782-811.
Crossref
Harsha Jain, Harshita Dalvi, Aditi Bhat, Aashruti Agrawal, Jitender Madan, Pankaj Kumar Singh, Neelesh Kumar Mehra, Shashi Bala Singh & Saurabh Srivastava. 2022. Multifunctional Nanocarriers. Multifunctional Nanocarriers 379 400 .
Milad Roshani, Nasim Kiaie & Rouhollah Mehdinavaz Aghdam. (2021) Biomaterials and stem cells as drug/gene-delivery vehicles for Parkinson's treatment: an update. Regenerative Medicine 16:12, pages 1057-1072.
Crossref
Jyotsna Shankar, Geetha K.M & Barnabas Wilson. (2021) Potential applications of nanomedicine for treating Parkinson's disease. Journal of Drug Delivery Science and Technology 66, pages 102793.
Crossref
Ajit Singh, Sandeep Kumar Maharana, Rahul Shukla & Prashant Kesharwani. (2021) Nanotherapeutics approaches for targeting alpha synuclien protein in the management of Parkinson disease. Process Biochemistry 110, pages 181-194.
Crossref
Jonathan Baskin, June Evelyn Jeon & Simon J. G. Lewis. (2020) Nanoparticles for drug delivery in Parkinson’s disease. Journal of Neurology 268:5, pages 1981-1994.
Crossref
Sara Silva, António Almeida & Nuno Vale. (2021) Importance of Nanoparticles for the Delivery of Antiparkinsonian Drugs. Pharmaceutics 13:4, pages 508.
Crossref
Ankit Tandon, Sangh J. Singh & Rajnish K. Chaturvedi. (2021) Nanomedicine against Alzheimer’s and Parkinson’s Disease. Current Pharmaceutical Design 27:12, pages 1507-1545.
Crossref
Elahehnaz Parhizkar, Zahra Mohammadi & Shohreh Alipour. (2021) Rapid High-Performance Liquid Chromatography Method for Levodopa Quantitation at Low UV Wavelength: Application of Pharmacokinetics Study in Rat Following Intranasal Delivery. Journal of Chromatographic Science 59:4, pages 347-354.
Crossref
Elena Bellotti, Andrea L. Schilling, Steven R. Little & Paolo Decuzzi. (2021) Injectable thermoresponsive hydrogels as drug delivery system for the treatment of central nervous system disorders: A review. Journal of Controlled Release 329, pages 16-35.
Crossref
Hitendra S. Mahajan & Payal H. Patil. 2021. Direct Nose-to-Brain Drug Delivery. Direct Nose-to-Brain Drug Delivery 225 245 .
Abhijeet Kulkarni, Mahesh Shinde, Gaurav Sonawane, Hitesh Raotole, Rohit Pande & Chandrakantsing V. Pardeshi. 2021. Direct Nose-to-Brain Drug Delivery. Direct Nose-to-Brain Drug Delivery 329 349 .
Yamini Madav & Sarika Wairkar. 2021. Direct Nose-to-Brain Drug Delivery. Direct Nose-to-Brain Drug Delivery 169 184 .
Prashant Upadhaya, Sreeranjini Pulakkat & Vandana Patravale. 2021. Direct Nose-to-Brain Drug Delivery. Direct Nose-to-Brain Drug Delivery 287 303 .
Ganesh B. Shevalkar, Mahendra K. Prajapati, Rohan V. Pai & Kamlesh D. Mali. 2021. Direct Nose-to-Brain Drug Delivery. Direct Nose-to-Brain Drug Delivery 249 266 .
Farrukh Zeeshan, Dinesh Kumar Mishra & Prashant Kesharwani. 2021. Theory and Applications of Nonparenteral Nanomedicines. Theory and Applications of Nonparenteral Nanomedicines 153 180 .
Nagma Banjare, Laxmikant Gautam, Chittaranjan Behera, Prem N. Gupta, Sonal Vyas & Suresh P. Vyas. (2020) Cyclodextrin nanosponges based site-retentive controlled release system for treatment of rheumatic arthritis. Journal of Drug Delivery Science and Technology 60, pages 101973.
Crossref
Mukta Agrawal, Shailendra Saraf, Swarnlata Saraf, Sunil K. Dubey, Anu Puri, Umesh Gupta, Prashant Kesharwani, V. Ravichandiran, Pramod Kumar, V.G.M. Naidu, Upadhyayula Suryanarayana Murty, Ajazuddin & Amit Alexander. (2020) Stimuli-responsive In situ gelling system for nose-to-brain drug delivery. Journal of Controlled Release 327, pages 235-265.
Crossref
Sara Hernando, Enara Herran, Rosa Maria Hernandez & Manoli Igartua. (2020) Nanostructured Lipid Carriers Made of Ω-3 Polyunsaturated Fatty Acids: In Vitro Evaluation of Emerging Nanocarriers to Treat Neurodegenerative Diseases. Pharmaceutics 12:10, pages 928.
Crossref
Ankita Paul & Khushwant S. Yadav. (2020) Parkinson's disease: Current drug therapy and unraveling the prospects of nanoparticles. Journal of Drug Delivery Science and Technology 58, pages 101790.
Crossref
Jesus Garcia-Chica, West Kristian D Paraiso, Shihori Tanabe, Dolors Serra, Laura Herrero, Núria Casals, Jordi Garcia, Xavier Ariza, Sabina Quader & Rosalia Rodriguez-Rodriguez. (2020) An overview of nanomedicines for neuron targeting. Nanomedicine 15:16, pages 1617-1636.
Crossref
Amrinder Singh, Shubham Thakur, Tushit Sharma, Manjot Kaur, Nikhil Shri Sahajpal, Rohan Aurora & Subheet Kumar Jain. (2020) Harmonious Biomaterials for Development of In situ Approaches for Locoregional Delivery of Anti-cancer Drugs: Current Trends. Current Medicinal Chemistry 27:21, pages 3463-3498.
Crossref
Mahasweta Paul & Raymond Lau. (2020) Potentials and challenges of Levodopa particle formulation for treatment of Parkinson’s disease through intranasal and pulmonary delivery. Advanced Powder Technology 31:6, pages 2357-2365.
Crossref
Doddy Denise Ojeda-Hernández, Alejandro A. Canales-Aguirre, Jorge Matias-Guiu, Ulises Gomez-Pinedo & Juan C. Mateos-Díaz. (2020) Potential of Chitosan and Its Derivatives for Biomedical Applications in the Central Nervous System. Frontiers in Bioengineering and Biotechnology 8.
Crossref
Mukta Agrawal, Swarnlata Saraf, Shailendra Saraf, Sunil Kumar Dubey, Anu Puri, Ravish J. Patel, Ajazuddin, V. Ravichandiran, Upadhyayula Suryanarayana Murty & Amit Alexander. (2020) Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting. Journal of Controlled Release 321, pages 372-415.
Crossref
Ramin Ansari, Seyed Mahdi Sadati, Negin Mozafari, Hajar Ashrafi & Amir Azadi. (2020) Carbohydrate polymer-based nanoparticle application in drug delivery for CNS-related disorders. European Polymer Journal 128, pages 109607.
Crossref
Aruna Sharma, Dafin F. Muresanu, Ala Nozari, José Vicente Lafuente, Seaab Sahib, Z. Ryan Tian, Anca D. Buzoianu, Ranjana Patnaik, Lars Wiklund & Hari Shanker Sharma. 2020. Neuropharmacology of Neuroprotection. Neuropharmacology of Neuroprotection 157 231 .
Nozad Rashid Hussein, Huner Kamal Omer, Abdelbary M.A. Elhissi & Waqar Ahmed. 2020. Advances in Medical and Surgical Engineering. Advances in Medical and Surgical Engineering 279 311 .
Reetuparna Nanda, Punyatoya Panda & Monalisa Mishra. 2020. Nanomaterials in Diagnostic Tools and Devices. Nanomaterials in Diagnostic Tools and Devices 479 523 .
Amita Sarwal, Gurpreet Singh, Priya Prasad, Sachin Sharma & Waseem Ali. 2020. Nanoformulations in Human Health. Nanoformulations in Human Health 187 203 .
Areen Alshweiat, Rita Ambrus & IIdikó Csóka. (2019) Intranasal Nanoparticulate Systems as Alternative Route of Drug Delivery. Current Medicinal Chemistry 26:35, pages 6459-6492.
Crossref
Blessing Atim Aderibigbe & Tobeka Naki. (2019) Chitosan-Based Nanocarriers for Nose to Brain Delivery. Applied Sciences 9:11, pages 2219.
Crossref
Qianwen Wang, Zhong Zuo, Cheuk Kit Chucky Cheung & Sharon Shui Yee Leung. (2019) Updates on thermosensitive hydrogel for nasal, ocular and cutaneous delivery. International Journal of Pharmaceutics 559, pages 86-101.
Crossref
José Vicente Lafuente, Catalina Requejo & Luisa Ugedo. 2019. Nanoneuroprotection and Nanoneurotoxicology. Nanoneuroprotection and Nanoneurotoxicology 263 279 .
Sonali Batra & Sumit Sharma. 2019. Materials for Biomedical Engineering. Materials for Biomedical Engineering 463 484 .
Sumit Sharma & Sonali Batra. 2019. Materials for Biomedical Engineering. Materials for Biomedical Engineering 97 119 .
Archana Khosa, Ranendra Narayan Saha & Gautam Singhvi. 2019. Nanomaterials for Drug Delivery and Therapy. Nanomaterials for Drug Delivery and Therapy 461 514 .
Ashok Kr. Parthipan, Nidhi Gupta, Kalpana Pandey, Bhavna Sharma, Josemon Jacob & Sampa Saha. (2018) One-step fabrication of bicompartmental microparticles as a dual drug delivery system for Parkinson’s disease management. Journal of Materials Science 54:1, pages 730-744.
Crossref
Chandrakantsing V. Pardeshi, Veena S. Belgamwar & Sanjay J. Surana. 2019. Nanobiotechnology in Neurodegenerative Diseases. Nanobiotechnology in Neurodegenerative Diseases 163 175 .
Jhonatas Rodrigues Barbosa, Maurício Madson dos Santos Freitas, Luiza Helena da Silva Martins, Andrea Komesu, Alessandra Santos Lopes, Raul Nunes de Carvalho Junior & Mahendra Rai. 2019. Nanobiotechnology in Neurodegenerative Diseases. Nanobiotechnology in Neurodegenerative Diseases 139 162 .
Josef Jampílek, Katarína Kráľová, Petr Novák & Michal Novák. 2019. Nanobiotechnology in Neurodegenerative Diseases. Nanobiotechnology in Neurodegenerative Diseases 65 138 .
Elena Giuliano, Donatella Paolino, Massimo Fresta & Donato Cosco. (2018) Mucosal Applications of Poloxamer 407-Based Hydrogels: An Overview. Pharmaceutics 10:3, pages 159.
Crossref
Anam Khan, Mohd. Aqil, Syed Sarim Imam, Abdul Ahad, Yasmin Sultana, Asgar Ali & Khalid Khan. (2018) Temozolomide loaded nano lipid based chitosan hydrogel for nose to brain delivery: Characterization, nasal absorption, histopathology and cell line study. International Journal of Biological Macromolecules 116, pages 1260-1267.
Crossref
Vassilis Bourganis, Olga Kammona, Aleck Alexopoulos & Costas Kiparissides. (2018) Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics. European Journal of Pharmaceutics and Biopharmaceutics 128, pages 337-362.
Crossref
Blessing Aderibigbe. (2018) In Situ-Based Gels for Nose to Brain Delivery for the Treatment of Neurological Diseases. Pharmaceutics 10:2, pages 40.
Crossref
Shadab Md, Subrat K. Bhattmisra, Farrukh Zeeshan, Naiyer Shahzad, Md Ali Mujtaba, Venkata Srikanth Meka, Ammu Radhakrishnan, Prashant Kesharwani, Sanjula Baboota & Javed Ali. (2018) Nano-carrier enabled drug delivery systems for nose to brain targeting for the treatment of neurodegenerative disorders. Journal of Drug Delivery Science and Technology 43, pages 295-310.
Crossref
Sara Hernando, Enara Herran, Joana Figueiro-Silva, José Luis Pedraz, Manoli Igartua, Eva Carro & Rosa Maria Hernandez. (2017) Intranasal Administration of TAT-Conjugated Lipid Nanocarriers Loading GDNF for Parkinson’s Disease. Molecular Neurobiology 55:1, pages 145-155.
Crossref
Shuaiqiang Zhang, Yan Nie, Hongyan Tao & Zongjin Li. 2018. Hydrogels. Hydrogels 87 112 .
Manpreet Kaur, Sumit Sharma & VR Sinha. (2017) Polymer based microspheres of aceclofenac as sustained release parenterals for prolonged anti-inflammatory effect. Materials Science and Engineering: C 72, pages 492-500.
Crossref
Daniela Silva Adaya, Lucinda Aguirre-Cruz, Jorge Guevara & Emma Ortiz-Islas. (2016) Nanobiomaterials’ applications in neurodegenerative diseases. Journal of Biomaterials Applications 31:7, pages 953-984.
Crossref
Banu Cahide Tel & Gul Yalçin Çakmakli. 2017. Nanotechnology Methods for Neurological Diseases and Brain Tumors. Nanotechnology Methods for Neurological Diseases and Brain Tumors 241 269 .
Sara Hernando, Enara Herran, Jose Luis Pedraz, Manoli Igartua & Rosa Maria Hernandez. 2017. Drug and Gene Delivery to the Central Nervous System for Neuroprotection. Drug and Gene Delivery to the Central Nervous System for Neuroprotection 57 87 .
Gabriel Henrique Hawthorne, Marcelo Picinin Bernuci, Mariza Bortolanza, Vitor Tumas, Ana Carolina Issy & Elaine Del-Bel. (2016) Nanomedicine to Overcome Current Parkinson’s Treatment Liabilities: A Systematic Review. Neurotoxicity Research 30:4, pages 715-729.
Crossref
Sara Hernando, Oihane Gartziandia, Enara Herran, Jose Luis Pedraz, Manoli Igartua & Rosa Maria Hernandez. (2016) Advances in nanomedicine for the treatment of Alzheimer’s and Parkinson’s diseases. Nanomedicine 11:10, pages 1267-1285.
Crossref
Giovanna Rassu, Elena Soddu, Massimo Cossu, Elisabetta Gavini, Paolo Giunchedi & Alessandro Dalpiaz. (2016) Particulate formulations based on chitosan for nose-to-brain delivery of drugs. A review. Journal of Drug Delivery Science and Technology 32, pages 77-87.
Crossref
Gerardo Leyva-Gómez, Hernán Cortés, Jonathan J. Magaña, Norberto Leyva-García, David Quintanar-Guerrero & Benjamín Florán. (2015) Nanoparticle technology for treatment of Parkinson's disease: the role of surface phenomena in reaching the brain. Drug Discovery Today 20:7, pages 824-837.
Crossref
Howard E. Gendelman, Vellareddy Anantharam, Tatiana Bronich, Shivani Ghaisas, Huajun Jin, Anumantha G. Kanthasamy, Xinming Liu, JoEllyn McMillan, R. Lee Mosley, Balaji Narasimhan & Surya K. Mallapragada. (2015) Nanoneuromedicines for degenerative, inflammatory, and infectious nervous system diseases. Nanomedicine: Nanotechnology, Biology and Medicine 11:3, pages 751-767.
Crossref
Laura Ravani, Maria Grazia Sarpietro, Elisabetta Esposito, Antonio Di Stefano, Piera Sozio, Mariangela Calcagno, Markus Drechsler, Catia Contado, Francesco Longo, Maria Chiara Giuffrida, Francesco Castelli, Michele Morari & Rita Cortesi. (2015) Lipid nanocarriers containing a levodopa prodrug with potential antiparkinsonian activity. Materials Science and Engineering: C 48, pages 294-300.
Crossref
Jayrajsinh Sarvaiya & Y.K. Agrawal. (2015) Chitosan as a suitable nanocarrier material for anti-Alzheimer drug delivery. International Journal of Biological Macromolecules 72, pages 454-465.
Crossref
Kaisar Raza, Manish Kumar, Pramod Kumar, Ruchi Malik, Gajanand Sharma, Manmeet Kaur & O. P. Katare. (2014) Topical Delivery of Aceclofenac: Challenges and Promises of Novel Drug Delivery Systems. BioMed Research International 2014, pages 1-11.
Crossref
Meenakshi Malhotra, Catherine Tomaro-Duchesneau, Shyamali Saha & Satya Prakash. 2014. Drug Delivery System. Drug Delivery System 233 247 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.