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Drug Development and Industrial Pharmacy Volume 40, 2014 - Issue 12
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Research Article

Production of pure indinavir free base nanoparticles by a supercritical anti-solvent (SAS) method

Julieta C. ImperialeThe Group of Biomaterials and Nanotechnology for Improved Medicines (BIONIMED), Department of Pharmaceutical Technology, Faculty of Pharmacy and Biochemistry, University of Buenos Aires Buenos AiresArgentina
,
Gabriela BevilacquaDepartment of Physical Chemistry, Institute of Chemistry, State University of Campinas CampinasBrazil
,
Paulo de Tarso Vieira e RosaDepartment of Physical Chemistry, Institute of Chemistry, State University of Campinas CampinasBrazil
&
Alejandro SosnikThe Group of Biomaterials and Nanotechnology for Improved Medicines (BIONIMED), Department of Pharmaceutical Technology, Faculty of Pharmacy and Biochemistry, University of Buenos Aires Buenos AiresArgentina;National Science Research Council (CONICET) Buenos AiresArgentinaCorrespondence[email protected]
Pages 1607-1615 | Received 13 Jun 2013, Accepted 18 Aug 2013, Published online: 19 Sep 2013

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Masoumeh Kurd, Soroor Sadegh Malvajerd, Saeed Rezaee, Mehrdad Hamidi & Katayoun Derakhshandeh. (2019) Oral delivery of indinavir using mPEG-PCL nanoparticles: preparation, optimization, cellular uptake, transport and pharmacokinetic evaluation. Artificial Cells, Nanomedicine, and Biotechnology 47:1, pages 2123-2133.
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Articles from other publishers (16)

Prasanta Kumar Mohapatra, Rajnish Srivastava, Krishna Kumar Varshney, Sunit Kumar Sahoo & Asha Kesari. (2023) A Computational Approach for Exploring Indinavir as a Potent Protease Inhibitor and Development of Its Microsphere for Anticancer Activity. Journal of Pharmaceutical Innovation.
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Bingchan Liang, Jianxia Hao, Ning Zhu, Limin Han, Lijun Song & Hailong Hong. (2023) Formulation of nitrendipine/hydroxypropyl-β-cyclodextrin inclusion complex as a drug delivery system to enhance the solubility and bioavailability by supercritical fluid technology. European Polymer Journal 187, pages 111880.
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Rahul Kumar, Amit K. Thakur, Gergely Kali, Kancharlapalli Chinaraga Pitchaiah, Raj Kumar Arya & Anurag Kulabhi. (2022) Particle preparation of pharmaceutical compounds using supercritical antisolvent process: current status and future perspectives. Drug Delivery and Translational Research 13:4, pages 946-965.
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Gholamhossein Sodeifian & Mohammad Mahdi Behvand Usefi. (2022) Solubility, Extraction, and Nanoparticles Production in Supercritical Carbon Dioxide: A Mini‐Review. ChemBioEng Reviews 10:2, pages 133-166.
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Siddhesh Jadhav, Nikhil Yenorkar, Ruchika Bondre, Megha Karemore & Nikhil Bali. (2022) Nanomedicines encountering HIV dementia: A guiding star for neurotherapeutics. Journal of Drug Delivery Science and Technology 71, pages 103315.
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Hamze Salehi, Mehrnaz Karimi & Farhad Raofie. (2021) Micronization and coating of bioflavonoids extracted from Citrus sinensis L. peels to preparation of sustained release pellets using supercritical technique. Journal of the Iranian Chemical Society 18:12, pages 3235-3248.
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Ranjith Kumar Kankala, Pei-Yao Xu, Biao-Qi Chen, Shi-Bin Wang & Ai-Zheng Chen. (2021) Supercritical fluid (SCF)-assisted fabrication of carrier-free drugs: An eco-friendly welcome to active pharmaceutical ingredients (APIs). Advanced Drug Delivery Reviews 176, pages 113846.
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Roni Sverdlov Arzi, Asaf Kay, Yulia Raychman & Alejandro Sosnik. (2021) Excipient-Free Pure Drug Nanoparticles Fabricated by Microfluidic Hydrodynamic Focusing. Pharmaceutics 13:4, pages 529.
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Mamunur Rashid, Mohd Yaseen Malik, Sandeep K. Singh, Swati Chaturvedi, Jiaur R Gayen & Muhammad Wahajuddin. (2019) Bioavailability Enhancement of Poorly Soluble Drugs: The Holy Grail in Pharma Industry. Current Pharmaceutical Design 25:9, pages 987-1020.
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Anagha Bhakay, Mahbubur Rahman, Rajesh Dave & Ecevit Bilgili. (2018) Bioavailability Enhancement of Poorly Water-Soluble Drugs via Nanocomposites: Formulation–Processing Aspects and Challenges. Pharmaceutics 10:3, pages 86.
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Luís Padrela, Miguel A. Rodrigues, Andreia Duarte, Ana M.A. Dias, Mara E.M. Braga & Hermínio C. de Sousa. (2018) Supercritical carbon dioxide-based technologies for the production of drug nanoparticles/nanocrystals – A comprehensive review. Advanced Drug Delivery Reviews 131, pages 22-78.
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Sharif Md Abuzar, Sang-Min Hyun, Jun-Hee Kim, Hee Jun Park, Min-Soo Kim, Jeong-Sook Park & Sung-Joo Hwang. (2018) Enhancing the solubility and bioavailability of poorly water-soluble drugs using supercritical antisolvent (SAS) process. International Journal of Pharmaceutics 538:1-2, pages 1-13.
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Ranjith Kumar Kankala, Yu Shrike Zhang, Shi-Bin Wang, Chia-Hung Lee & Ai-Zheng Chen. (2017) Supercritical Fluid Technology: An Emphasis on Drug Delivery and Related Biomedical Applications. Advanced Healthcare Materials 6:16, pages 1700433.
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Jean Cornier, Andrew Owen, Arno Kwade & Marcel Van de VoordeAlejandro Sosnik. 2017. Pharmaceutical Nanotechnology: Innovation and Production. Pharmaceutical Nanotechnology: Innovation and Production 579 602 .
José das Neves, Rute Nunes, Francisca Rodrigues & Bruno Sarmento. (2016) Nanomedicine in the development of anti-HIV microbicides. Advanced Drug Delivery Reviews 103, pages 57-75.
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Alejandro Sosnik & Robin Augustine. (2016) Challenges in oral drug delivery of antiretrovirals and the innovative strategies to overcome them. Advanced Drug Delivery Reviews 103, pages 105-120.
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