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Research Article

Differential effects of ketoconazole, itraconazole and voriconazole on the pharmacokinetics of imatinib and its main metabolite GCP74588 in rat

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Pages 1616-1622 | Received 19 Jun 2013, Accepted 21 Aug 2013, Published online: 20 Sep 2013

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Read on this site (7)

Jiquan Shen, Bo Wang, Shuanghu Wang, Feifei Chen, Deru Meng, Hui Jiang, Yunfang Zhou, Peiwu Geng, Quan Zhou & Bin Liu. (2020) Effects of Voriconazole on the Pharmacokinetics of Vonoprazan in Rats. Drug Design, Development and Therapy 14, pages 2199-2206.
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Yunfang Zhou, Shuanghu Wang, Ting Ding, Mingdong Wu, Peiwu Geng, Qingwei Zhang & Jianshe Ma. (2015) Pharmacokinetic interaction study of combining imatinib with dasatinib in rats by UPLC–MS/MS. Drug Development and Industrial Pharmacy 41:12, pages 1948-1953.
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Li Wang, Fan Wu, Jia Xu, Yu Wang, Weidong Fei, Hui Jiang, Peiwu Geng, Quan Zhou, Shuanghu Wang, Yongquan Zheng & Huadong Deng. (2022) Differential effects of ketoconazole, fluconazole, and itraconazole on the pharmacokinetics of pyrotinib in vitro and in vivo. Frontiers in Pharmacology 13.
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Jun Wang, Xiao Cui, Chen Cheng, Yi Wang, Wei Sun, Cheng-ke Huang, Rui-jie Chen & Zhe Wang. (2021) Effects of CYP3A inhibitors ketoconazole, voriconazole, and itraconazole on the pharmacokinetics of sunitinib and its main metabolite in rats. Chemico-Biological Interactions 338, pages 109426.
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Ruba S. Darweesh, Tamam El-Elimat, Aref Zayed, Tareq N. Khamis, Wahby M. Babaresh, Tawfiq Arafat & Ahmed H. Al Sharie. (2020) The effect of grape seed and green tea extracts on the pharmacokinetics of imatinib and its main metabolite, N-desmethyl imatinib, in rats. BMC Pharmacology and Toxicology 21:1.
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Xingxian Luo, Xuecai Xue, Taifeng Li, Ying Zhang, Lin Huang & Gang Cheng. (2020) Differential Impacts of Azole Antifungal Drugs on the Pharmacokinetic Profiles of Dasatinib in Rats by LC-MS-MS. Current Drug Metabolism 21:13, pages 1022-1030.
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Leibin Shen, Jun Wang, Yongdong Yi, Chenmin Ye, Rongrong Wang, Guojun Xia, Chengyang Yu, Fuyang Tu, Jingxuan Xu & Zhiqiang Zheng. (2018) Inhibitory effect of isavuconazole, ketoconazole, and voriconazole on the pharmacokinetics of methadone in vivo and in vitro. Drug Testing and Analysis 11:4, pages 595-600.
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Ren-ai Xu, Qianmeng Lin, Xiangjun Qiu, Jingjing Chen, Yuanyuan Shao, Guoxin Hu & Guanyang Lin. (2019) UPLC-MS/MS method for the simultaneous determination of imatinib, voriconazole and their metabolites concentrations in rat plasma. Journal of Pharmaceutical and Biomedical Analysis 166, pages 6-12.
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Ye Xu, Xiaoyan Chen & Dafang Zhong. (2018) A sensitive LC–MS/MS method for the determination of triptolide and its application to pharmacokinetic research in rats. Biomedical Chromatography 33:3, pages e4422.
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Zhengyu Yan, Kun Yan, Xingliang He, Yanhua Liu, Jie Zhang, Oscar Lopez Torres, Ruixin Guo & Jianqiu Chen. (2017) The impact assessment of anticancer drug imatinib on the feeding behavior of rotifers with an integrated perspective: Exposure, post-exposure and re-exposure. Chemosphere 185, pages 423-430.
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Caroline Gay, Delphine Toulet & Pascal Le Corre. (2017) Pharmacokinetic drug-drug interactions of tyrosine kinase inhibitors: A focus on cytochrome P450, transporters, and acid suppression therapy. Hematological Oncology 35:3, pages 259-280.
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