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Research Article

Formulation and pharmacokinetics of gelucire solid dispersions of flurbiprofen

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Pages 1254-1262 | Received 10 Mar 2014, Accepted 26 Jun 2014, Published online: 21 Jul 2014

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Silvana A. Barea, Cristiane B. Mattos, Ariadne C. C. Cruz, Vitor C. Chaves, Rafael N. Pereira, Claudia M. O. Simões, Jadel M. Kratz & Letícia S. Koester. (2017) Solid dispersions enhance solubility, dissolution, and permeability of thalidomide. Drug Development and Industrial Pharmacy 43:3, pages 511-518.
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Kun Zhao, Yue Yuan, Hui Wang, Panpan Li, Zhihong Bao & Yue Li. (2016) Preparation and evaluation of valsartan by a novel semi-solid self-microemulsifying delivery system using Gelucire 44/14. Drug Development and Industrial Pharmacy 42:10, pages 1545-1552.
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Articles from other publishers (10)

Sateesh Kumar Vemula, Bhaskar Daravath & Michael Repka. (2023) Quality by design (QbD) approach to develop fast-dissolving tablets using melt-dispersion paired with surface-adsorption method: formulation and pharmacokinetics of flurbiprofen melt-dispersion granules. Drug Delivery and Translational Research 13:12, pages 3204-3222.
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Muhammad Usman Munir, Mahnoor Ikraam, Muhammad Nadeem, Syed Haroon Khalid, Sajid Asghar, Ikrima Khalid, Muhammad Irfan, Nayyer Islam, Nyla Ajaz & Ikram Ullah Khan. (2022) Fabrication, In Vitro and In Vivo Evaluation of Non-Ordered Mesoporous Silica-Based Ternary Solid Dispersions for Enhanced Solubility of Flurbiprofen. Pharmaceuticals 15:7, pages 856.
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Bhaskar Daravath & Shalini Somalanka. (2022) Enhancement of dissolution rate of racecadotril by liquisolid compact technology. Brazilian Journal of Pharmaceutical Sciences 58.
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Phuong Tran, Yong-Chul Pyo, Dong-Hyun Kim, Sang-Eun Lee, Jin-Ki Kim & Jeong-Sook Park. (2019) Overview of the Manufacturing Methods of Solid Dispersion Technology for Improving the Solubility of Poorly Water-Soluble Drugs and Application to Anticancer Drugs. Pharmaceutics 11:3, pages 132.
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Haley McFall, Sandeep Sarabu, Vijaykumar Shankar, Suresh Bandari, S. Narasimha Murthy, Karl Kolter, Nigel Langley, Dong Wuk Kim & Michael A. Repka. (2019) Formulation of aripiprazole-loaded pH-modulated solid dispersions via hot-melt extrusion technology: In vitro and in vivo studies. International Journal of Pharmaceutics 554, pages 302-311.
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Xingwang Zhang, Huijie Xing, Yue Zhao & Zhiguo Ma. (2018) Pharmaceutical Dispersion Techniques for Dissolution and Bioavailability Enhancement of Poorly Water-Soluble Drugs. Pharmaceutics 10:3, pages 74.
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Bhaskar Daravath, Chella Naveen, Sateesh Kumar Vemula & Rama Rao Tadikonda. (2018) Solubility and dissolution enhancement of flurbiprofen by solid dispersion using hydrophilic carriers. Brazilian Journal of Pharmaceutical Sciences 53:4.
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Petra Zimmermann & Nigel Curtis. (2017) Antimicrobial Effects of Antipyretics. Antimicrobial Agents and Chemotherapy 61:4.
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Sateesh K. Vemula & Santhosh G. Reddy. (2015) Formulation and Pharmacokinetics of Flurbiprofen Sublimated Fast Dissolving Tablets#. Open Pharmaceutical Sciences Journal 2:1, pages 56-65.
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Fakhar ud Din, Omer Mustapha, Dong Wuk Kim, Rehmana Rashid, Jong Hyuck Park, Ju Yeon Choi, Sae Kwang Ku, Chul Soon Yong, Jong Oh Kim & Han-Gon Choi. (2015) Novel dual-reverse thermosensitive solid lipid nanoparticle-loaded hydrogel for rectal administration of flurbiprofen with improved bioavailability and reduced initial burst effect. European Journal of Pharmaceutics and Biopharmaceutics 94, pages 64-72.
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