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Research Article

Evaluation of Anhydrous α-Lactose, A New Excipient in Direct Compression

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Pages 1657-1681 | Published online: 20 Oct 2008

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Read on this site (13)

Gerad K. Bolhuis, Erik G. Rexwinkel & Klaas Zuurman. (2009) Polyols as filler-binders for disintegrating tablets prepared by direct compaction. Drug Development and Industrial Pharmacy 35:6, pages 671-677.
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Z. Jelcic, K. Hauschild, M. Ogiermann & K. M. Picker-Freyer. (2007) Evaluation of Tablet Formation of Different Lactoses by 3D Modeling and Fractal Analysis. Drug Development and Industrial Pharmacy 33:4, pages 353-372.
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Mariarosa Moneghini, Antonio Carcano, Beatrice Perissutti & Fulvio Rubessa. (2000) Formulation Design Studies of Atenolol Tablets. Pharmaceutical Development and Technology 5:2, pages 297-301.
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Robert O. Williams, Mongkol Sriwongjanya & Melisa K. Barron. (1997) Compaction Properties of Microcrystalline Cellulose Using Tableting Indices. Drug Development and Industrial Pharmacy 23:7, pages 695-704.
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G. K. Bolhuis & K. Zuurman. (1995) Tableting Properties of Experimental and Commercially Available Lactose Granulations for Direct Compression. Drug Development and Industrial Pharmacy 21:18, pages 2057-2071.
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E. Doelker, D. Massuelle, F. Veuillez & P. Humbert-Droz. (1995) Morphological, Packing, Flow and Tableting Properties of New Avicel Types. Drug Development and Industrial Pharmacy 21:6, pages 643-661.
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E. Doelker. (1993) Comparative compaction properties of various Microcrystalline Cellulose types and Generic Products. Drug Development and Industrial Pharmacy 19:17-18, pages 2399-2471.
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C. E. Bos, G. K. Bolhuis, C. F. Lerk & C. A.A. Duineveld. (1992) Evaluation of modified rice starch, a new excipient for direct compression.. Drug Development and Industrial Pharmacy 18:1, pages 93-106.
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Atul J. Shukla & James C. Price. (1991) Effect of Moisture Content on Compression Properties of Directly Compressible High Beta-Content Anhydrous Lactose. Drug Development and Industrial Pharmacy 17:15, pages 2067-2081.
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C. E. Bos, G. K. Bolhuis, C. F. Lerk, J. H. De Boer, C. A. A. Duineveld, A. K. Smilde & D. A. Doornbos. (1991) Optimization of Direct Compression Tablet Formulations for Use in Tropical Countries. Drug Development and Industrial Pharmacy 17:18, pages 2477-2496.
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P. M. Thwaites, A. B. Mashadi & W.D. Moore. (1991) An Investigation of the Effect of High Speed Mixing on the Mechanical and Physical Properties of Direct Compression Lactose. Drug Development and Industrial Pharmacy 17:4, pages 503-517.
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G. K. Bolhuis, S. W. De Jong, C. F. Lerk, H. Dettmers & B. V. Pharbita. (1987) The Effect of Magnesium Stearate Admixing in Different Types of Laboratory and Industrial Mixers on Tablet Crushing Strength. Drug Development and Industrial Pharmacy 13:9-11, pages 1547-1567.
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Articles from other publishers (32)

Cedrine de Backere, Thomas De Beer, Chris Vervaet & Valérie Vanhoorne. (2023) Upscaling of external lubrication from a compaction simulator to a rotary tablet press. International Journal of Pharmaceutics 633, pages 122616.
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Cedrine de Backere, Margot Surmont, Thomas De Beer, Chris Vervaet & Valérie Vanhoorne. (2023) Screening of lubricants towards their applicability for external lubrication. International Journal of Pharmaceutics 632, pages 122553.
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Cedrine de Backere, Julian Quodbach, Thomas De Beer, Chris Vervaet & Valérie Vanhoorne. (2022) Impact of alternative lubricants on process and tablet quality for direct compression. International Journal of Pharmaceutics 624, pages 122012.
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Cedrine de Backere, Thomas De Beer, Chris Vervaet & Valérie Vanhoorne. (2021) Effect of binder type and lubrication method on the binder efficacy for direct compression. International Journal of Pharmaceutics 607, pages 120968.
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Nizar Al-Zoubi, Shadi Gharaibeh, Ahmad Aljaberi & Ioannis Nikolakakis. (2021) Spray Drying for Direct Compression of Pharmaceuticals. Processes 9:2, pages 267.
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Amol Batra, Dipen Desai & Abu T.M. Serajuddin. (2020) Conversion of α-lactose monohydrate to anhydrous form with superior tabletability by twin-screw extrusion at elevated temperature. International Journal of Pharmaceutics 588, pages 119790.
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Cedrine de Backere, Thomas De Beer, Chris Vervaet & Valérie Vanhoorne. (2020) Evaluation of an external lubrication system implemented in a compaction simulator. International Journal of Pharmaceutics 587, pages 119675.
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Mohamad Jamal Altamimi, Kim Wolff, Ali Nokhodchi, Gary P. Martin & Paul G. Royall. (2019) Variability in the α and β anomer content of commercially available lactose. International Journal of Pharmaceutics 555, pages 237-249.
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Ben J. Bowles, Karolina Dziemidowicz, Felipe L. Lopez, Mine Orlu, Catherine Tuleu, Andrew J. Edwards & Terry B. Ernest. (2018) Co-Processed Excipients for Dispersible Tablets–Part 1: Manufacturability. AAPS PharmSciTech 19:6, pages 2598-2609.
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Pól MacFhionnghaile, Vaclav Svoboda, John McGinty, Alison Nordon & Jan Sefcik. (2017) Crystallization Diagram for Antisolvent Crystallization of Lactose: Using Design of Experiments To Investigate Continuous Mixing-Induced Supersaturation. Crystal Growth & Design 17:5, pages 2611-2621.
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Uzma Asif, Asif K. Sherwani, Naheed Akhtar, Muhammad Harris Shoaib, Muhammad Hanif, Muhammad Imran Qadir & Muhammad Zaman. (2016) Formulation Development and Optimization of Febuxostat Tablets by Direct Compression Method. Advances in Polymer Technology 35:2, pages 129-135.
Crossref
. 2016. Pharmaceutical Dosage Forms - Tablets. Pharmaceutical Dosage Forms - Tablets 671 672 .
Changquan Calvin Sun. (2015) Dependence of ejection force on tableting speed—A compaction simulation study. Powder Technology 279, pages 123-126.
Crossref
O C Chidavaenzi, G Buckton & F Koosha. (1998) The impact of feed temperature on the polymorphic content of spray dried lactose. Journal of Pharmacy and Pharmacology 50:Supplement_9, pages 184-184.
Crossref
N Armstrong. 2008. Pharmaceutical Dosage Forms - Tablets. Pharmaceutical Dosage Forms - Tablets 251 267 .
S. E. Emshanova. (2008) Methodological approaches to the selection of excipients for preparation of tablets by direct pressing. Pharmaceutical Chemistry Journal 42:2, pages 89-94.
Crossref
Xiaorong He, Pamela J. Secreast & Gregory E. Amidon. (2007) Mechanistic Study of the Effect of Roller Compaction and Lubricant on Tablet Mechanical Strength. Journal of Pharmaceutical Sciences 96:5, pages 1342-1355.
Crossref
V. Busignies, P. Tchoreloff, B. Leclerc, M. Besnard & G. Couarraze. (2004) Compaction of crystallographic forms of pharmaceutical granular lactoses. I. Compressibility. European Journal of Pharmaceutics and Biopharmaceutics 58:3, pages 569-576.
Crossref
Herbert StickerHerbert Sticker. 2003. Arzneiformen-Entwicklung. Arzneiformen-Entwicklung 97 127 .
Anko C. Eissens, Gerad K. Bolhuis, Wouter L.J. Hinrichs & Henderik W. Frijlink. (2002) Inulin as filler-binder for tablets prepared by direct compaction. European Journal of Pharmaceutical Sciences 15:1, pages 31-38.
Crossref
Gerad K Bolhuis, Anko C Eissens & Edzo Zoestbergen. (2001) DC Calcium lactate, a new filler-binder for direct compaction of tablets. International Journal of Pharmaceutics 221:1-2, pages 77-86.
Crossref
Tsuimin Tsai, Yu-Ping San, Hsiu-O Ho, Jen-Sen Wu & Ming-Thau Sheu. (1998) Film-forming polymer-granulated excipients as the matrix materials for controlled release dosage forms. Journal of Controlled Release 51:2-3, pages 289-299.
Crossref
C.E. Bos, G.K. Bolhuis, A.K. Smilde & J.H. de Boer. 1996. Robustness of analytical chemical methods and pharmaceutical technological products. Robustness of analytical chemical methods and pharmaceutical technological products 309 341 .
Gerad Bolhuis & Arne Hölzer. 1995. Pharmaceutical Powder ComPattion Technology. Pharmaceutical Powder ComPattion Technology 517 560 .
Gerad Bolhuis & Zak Chowhan. 1995. Pharmaceutical Powder ComPattion Technology. Pharmaceutical Powder ComPattion Technology 419 500 .
K.A. Riepma, H. Vromans & C.F. Lerk. (1993) A coherent matrix model for the consolidation and compaction of an excipient with magnesium stearate. International Journal of Pharmaceutics 97:1-3, pages 195-203.
Crossref
M. Angberg, C. Nystr?m & S. Castensson. (1992) Evaluation of heat-conduction microcalorimetry in pharmaceutical stability studies. V. A new approach for continuous measurements in abundant water vapour. International Journal of Pharmaceutics 81:2-3, pages 153-167.
Crossref
M. Angberg, C. Nystr?m & S. Castensson. (1991) Evaluation of heat-conduction microcalorimetry in pharmaceutical stability studies. III. Crystallographic changes due to water vapour uptake in anhydrous lactose powder. International Journal of Pharmaceutics 73:3, pages 209-220.
Crossref
H. Vromans, G.K. Bolhuis & C.F. Lerk. (1988) Magnesium stearate susceptibility of directly compressible materials as an indication of fragmentation properties. Powder Technology 54:1, pages 39-44.
Crossref
Herman V. van Kamp, Gerad K. Bolhuis & Coenraad F. Lerk. (1987) Optimization of a formulation for direct compression using a simplex lattice design. Pharmaceutisch Weekblad 9:5, pages 265-273.
Crossref
H.V. van Kamp, G.K. Bolhuis, K.D. Kussendrager & C.F. Lerk. (1986) Studies on tableting properties of lactose. IV. Dissolution and disintegration properties of different types of crystalline lactose. International Journal of Pharmaceutics 28:2-3, pages 229-238.
Crossref
H. Vromans, A. H. De Boer, G. K. Bolhuis, C. F. Lerk, K. D. Kussendrager & H. Bosch. (1985) Studies on tableting properties of lactose. Pharmaceutisch Weekblad 7:5, pages 186-193.
Crossref

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