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Research Article

Non Classical Experimental Designs in Pharmaceutical Formulation

Pages 1551-1570 | Published online: 20 Oct 2008

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Read on this site (9)

Vijay Mishra, Sourav Thakur, Akshay Patil & Anshuman Shukla. (2018) Quality by design (QbD) approaches in current pharmaceutical set-up. Expert Opinion on Drug Delivery 15:8, pages 737-758.
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Chengxiao Wang, Jianfang Ma, Ran Liu, Wei Han & Xiuzhen Tang. (2014) A thermoplastic elastomer patch matrix for traditional Chinese medicine: design and evaluation. Drug Development and Industrial Pharmacy 40:2, pages 211-221.
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Shan Ren, Huiling Mu, Fadi Alchaer, Azeddine Chtatou & Anette Müllertz. (2013) Optimization of self nanoemulsifying drug delivery system for poorly water-soluble drug using response surface methodology. Drug Development and Industrial Pharmacy 39:5, pages 799-806.
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Yves Gonnissen, Sara Isabel Vieira Gonçalves, Jean Paul Remon & Chris Vervaet. (2008) Mixture Design Applied to Optimize a Directly Compressible Powder Produced via Cospray Drying. Drug Development and Industrial Pharmacy 34:3, pages 248-257.
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R. Holm, I. H. M. Jensen & J. Sonnergaard. (2006) Optimization of Self-Microemulsifying Drug Delivery Systems (SMEDDS) Using a D-Optimal Design and the Desirability Function. Drug Development and Industrial Pharmacy 32:9, pages 1025-1032.
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B. Rambali, G. Verreck, L. Baert & D. L. Massart. (2003) Itraconazole Formulation Studies of the Melt-Extrusion Process with Mixture Design. Drug Development and Industrial Pharmacy 29:6, pages 641-652.
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Greg F. Piepel. (1999) Modeling Methods for Mixture-of-Mixtures Experiments Applied to a Tablet Formulation Problem. Pharmaceutical Development and Technology 4:4, pages 593-606.
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Dario Vojnovic & Daniela Chicco. (1997) Mixture Experimental Design Applied to Solubility Predictions. Drug Development and Industrial Pharmacy 23:7, pages 639-645.
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D. Vojnovic, M. Moneghini & D. Chicco. (1996) Nonclassical Experimental Design Applied in the Optimization of a Placebo Granulate Formulation in High-Shear Mixer. Drug Development and Industrial Pharmacy 22:9-10, pages 997-1004.
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Articles from other publishers (13)

Sonal Mehrotra, Salwa & Lalit Kumar. (2023) Implementation of Quality by Design in the Formulation and Development of Nanocarrier-Based Drug Delivery Systems. Critical Reviews™ in Therapeutic Drug Carrier Systems 40:3, pages 1-46.
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Jimin Hwang, Sonya Mros, Allan B. Gamble, Joel D. A. Tyndall & Arlene McDowell. (2022) Improving Antibacterial Activity of a HtrA Protease Inhibitor JO146 against Helicobacter pylori: A Novel Approach Using Microfluidics-Engineered PLGA Nanoparticles. Pharmaceutics 14:2, pages 348.
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. 2016. Pharmaceutical Dosage Forms - Tablets. Pharmaceutical Dosage Forms - Tablets 647 658 .
Amit Mirani & Vandana Patravale. 2016. Pharmaceutical Product Development. Pharmaceutical Product Development 117 162 .
Emmanuel Akala, Simeon Adesina & Oluwaseun Ogunwuyi. (2015) Computer Optimization of Biodegradable Nanoparticles Fabricated by Dispersion Polymerization. International Journal of Environmental Research and Public Health 13:1, pages 47.
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Thomas Quinten, Yves Gonnissen, Els Adriaens, Thomas De Beer, Veerle Cnudde, Bert Masschaele, Luc Van Hoorebeke, Juergen Siepmann, Jean Paul Remon & Chris Vervaet. (2009) Development of injection moulded matrix tablets based on mixtures of ethylcellulose and low-substituted hydroxypropylcellulose. European Journal of Pharmaceutical Sciences 37:3-4, pages 207-216.
Crossref
Fridrun Podczeck. 2008. Pharmaceutical Dosage Forms - Tablets. Pharmaceutical Dosage Forms - Tablets 105 135 .
Jay Trivedi. 2008. Water-Insoluble Drug Formulation, Second Edition. Water-Insoluble Drug Formulation, Second Edition 161 194 .
N Anthony Armstrong. 2006. Pharmaceutical Experimental Design and Interpretation, 2nd Edition. Pharmaceutical Experimental Design and Interpretation, 2nd Edition 135 156 .
J.-Y Cherng, H Talsma, R Verrijk, D.J.A Crommelin & W.E Hennink. (1999) The effect of formulation parameters on the size of poly((2-dimethylamino)ethyl methacrylate)-plasmid complexes. European Journal of Pharmaceutics and Biopharmaceutics 47:3, pages 215-224.
Crossref
Gareth Lewis, Didier Mathieu & Roger Phan-Tan-Luu. 1998. Pharmaceutical Experimental Design. Pharmaceutical Experimental Design.
Bärbel Rotthäuser, Gerolf Kraus & Peter C Schmidt. (1998) Optimization of an effervescent tablet formulation using a central composite design optimization of an effervescent tablet formulation containing spray dried l-leucine and polyethylene glycol 6000 as lubricants using a central composite design. European Journal of Pharmaceutics and Biopharmaceutics 46:1, pages 85-94.
Crossref
A. C. Atkinson. (1996) The Usefulness of Optimum Experimental Designs. Journal of the Royal Statistical Society: Series B (Methodological) 58:1, pages 59-76.
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