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Research Article

Formulation and Compaction of Microspheres

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Pages 3151-3173 | Published online: 20 Oct 2008

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Read on this site (13)

Mona Hassan Aburahma & Yassin El-Said Hamza. (2011) Novel sustained-release fast-disintegrating multi-unit compressed tablets of lornoxicam containing Eudragit RS coated chitosan-alginate beads. Pharmaceutical Development and Technology 16:4, pages 316-330.
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Stuart L. Cantor, Stephen W. Hoag & Larry L. Augsburger. (2009) Formulation and Characterization of a Compacted Multiparticulate System for Modified Release of Water-Soluble Drugs—Part II Theophylline and Cimetidine. Drug Development and Industrial Pharmacy 35:5, pages 568-582.
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Stuart L. Cantor, Stephen W. Hoag & Larry L. Augsburger. (2009) Evaluation of the mechanical properties of extrusion-spheronized beads and multiparticulate systems. Drug Development and Industrial Pharmacy 35:6, pages 683-693.
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Omaima N. El‐Gazayerly, Vipaporn Rakkanka & James W. Ayres. (2004) Novel Chewable Sustained‐Release Tablet Containing Verapamil Hydrochloride. Pharmaceutical Development and Technology 9:2, pages 181-188.
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Syed A. Altaf, Stephen W. Hoag & James W. Ayres. (1999) Bead Compacts. II. Evaluation of Rapidly Disintegrating Nonsegregating Compressed Bead Formulations. Drug Development and Industrial Pharmacy 25:5, pages 635-642.
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Robert A. Miller, Edwin M. K. Leung & Randal J. Oates. (1999) The Compression of Spheres Coated with an Aqueous Ethylcellulose Dispersion. Drug Development and Industrial Pharmacy 25:4, pages 503-511.
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A. GURSOY, D. KARAKUS, I. OKAR. (1999) Polymers for sustained release formulations of dipyridamole-alginate microspheres and tabletted microspheres. Journal of Microencapsulation 16:4, pages 439-452.
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Syed A. Altaf, Stephen W. Hoag & James W. Ayres. (1998) Bead Compacts. I. Effect of Compression on Maintenance of Polymer Coat Integrity in Multilayered Bead Formulations. Drug Development and Industrial Pharmacy 24:8, pages 737-746.
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Nathaniel O. Iloañusi & Joseph B. Schwartz. (1998) The Effect of Wax on Compaction of Microcrystalline Cellulose Beads Made by Extrusion and Spheronization. Drug Development and Industrial Pharmacy 24:1, pages 37-44.
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Chen-Chao Wang, James W. Mcginity, Guohua Zhang, Navnit H. Shah, Martin H. Infeld & A. Waseem Malick. (1996) Mechanical Properties of Single Pellets Containing Acrylic Polymers. Pharmaceutical Development and Technology 1:2, pages 213-222.
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Metin Çelik, John T. H. Ong, Zak T. Chowhan & Glenn J. Samuel. (1996) Compaction Simulator Studies of a New Drug Substance: Effect of Particle Size and Shape, and Its Binary Mixtures with Microcrystalline Cellulose. Pharmaceutical Development and Technology 1:2, pages 119-126.
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Metin Çelik. (1996) The Past, Present, and Future of Tableting Technology. Drug Development and Industrial Pharmacy 22:1, pages 1-10.
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Articles from other publishers (14)

Carin Ru Shan Siow, Paul Wan Sia Heng & Lai Wah Chan. (2020) A study on the impact of HPMC viscosity grade and proportion on the functional properties of co-freeze-dried mannitol-HPMC cushioning excipients for compacted MUPS. European Journal of Pharmaceutics and Biopharmaceutics 151, pages 98-107.
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Min Xu, Paul Wan Sia Heng & Celine Valeria Liew. (2016) Formulation and process strategies to minimize coat damage for compaction of coated pellets in a rotary tablet press: A mechanistic view. International Journal of Pharmaceutics 499:1-2, pages 29-37.
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Tingting Peng, Chune Zhu, Ying Huang, Guilan Quan, Linchong Huang, Linna Wu, Xin Pan, Ge Li & Chuanbin Wu. (2015) Improvement of the stability of doxycycline hydrochloride pellet-containing tablets through a novel granulation technique and proper excipients. Powder Technology 270, pages 221-229.
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Xiao Lin, Chin Wun Chyi, Ke-feng Ruan, Yi Feng & Paul Wan Sia Heng. (2011) Development of potential novel cushioning agents for the compaction of coated multi-particulates by co-processing micronized lactose with polymers. European Journal of Pharmaceutics and Biopharmaceutics 79:2, pages 406-415.
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J.L. Gomez-Amoza & R. Martinez-Pacheco. (2010) Influence of microstructure on drug release from extrusion-spheronization pellets. Journal of Drug Delivery Science and Technology 20:4, pages 319-325.
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Juan Torrado. 2008. Pharmaceutical Dosage Forms - Tablets. Pharmaceutical Dosage Forms - Tablets 509 532 .
Juan Torrado & Larry Augsburger. 2008. Pharmaceutical Dosage Forms - Tablets, Third Edition. Pharmaceutical Dosage Forms - Tablets, Third Edition 1140 1163 .
Ana Gómez-Carracedo, Consuelo Souto, Ramón Martı´nez-Pacheco, Angel Concheiro & Jose Luis Gómez-Amoza. (2008) Incidence of drying on microstructure and drug release profiles from tablets of MCC–lactose–Carbopol® and MCC–dicalcium phosphate–Carbopol® pellets. European Journal of Pharmaceutics and Biopharmaceutics 69:2, pages 675-685.
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Toshihiro Shimizu, Masae Sugaya, Yoshinori Nakano, Daisuke Izutsu, Yoshio Mizukami, Kazuhiro Okochi, Tetsuro Tabata, Naoru Hamaguchi & Yasutaka Igari. (2003) Formulation Study for Lansoprazole Fast-disintegrating Tablet. III. Design of Rapidly Disintegrating Tablets. CHEMICAL & PHARMACEUTICAL BULLETIN 51:10, pages 1121-1127.
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G.J Vergote, F Kiekens, C Vervaet & J.P Remon. (2002) Wax beads as cushioning agents during the compression of coated diltiazem pellets. European Journal of Pharmaceutical Sciences 17:3, pages 145-151.
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Mark T. DeCrosta, Joseph B. Schwartz, Rodney J. Wigent & Keith Marshall. (2000) Thermodynamic analysis of compact formation; compaction, unloading, and ejection. International Journal of Pharmaceutics 198:1, pages 113-134.
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Karl G. Wagner, Markus Krumme & Peter C. Schmidt. (1999) Investigation of the pellet-distribution in single tablets via image analysis. European Journal of Pharmaceutics and Biopharmaceutics 47:1, pages 79-85.
Crossref
Åsa E.K Lundqvist, Fridrun Podczeck & J Michael Newton. (1998) Compaction of, and drug release from, coated drug pellets mixed with other pellets. European Journal of Pharmaceutics and Biopharmaceutics 46:3, pages 369-379.
Crossref
Michael Salako, Fridrun Podczeck & J.Michael Newton. (1998) Investigations into the deformability and tensile strength of pellets. International Journal of Pharmaceutics 168:1, pages 49-57.
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