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Drug Development and Industrial Pharmacy Volume 20, 1994 - Issue 1
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Research Article

Granulation of Pharmaceutical Powders by Compaction an Experimental Study

P. Hervieu Sahut Conreur & Cie, BP 49 700 rue Corbeau 59590, Raismes, France
,
F. Dehont Sahut Conreur & Cie, BP 49 700 rue Corbeau 59590, Raismes, France
,
E. Jerome Faculty of Pharmacy, University of Lille, France
,
A. Delacourte Faculty of Pharmacy, University of Lille, France
&
J. C. Guyot Faculty of Pharmacy, University of Lille, France
Pages 65-74 | Published online: 20 Oct 2008

Citations (17)

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Read on this site (3)

Kitti Csordas, Raphael Wiedey & Peter Kleinebudde. (2018) Impact of roll compaction design, process parameters, and material deformation behaviour on ribbon relative density. Drug Development and Industrial Pharmacy 44:8, pages 1295-1306.
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Ana Pérez Gago & Peter Kleinebudde. (2017) MCC–mannitol mixtures after roll compaction/dry granulation: percolation thresholds for ribbon microhardness and granule size distribution. Pharmaceutical Development and Technology 22:6, pages 764-774.
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Jarunee Sakwanichol, Satit Puttipipatkhachorn, Gernot Ingenerf & Peter Kleinebudde. (2012) Roll compaction/dry granulation: Comparison between roll mill and oscillating granulator in dry granulation. Pharmaceutical Development and Technology 17:1, pages 30-39.
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Articles from other publishers (14)

Luca Palugan, Matteo Cerea, Carlo Vecchio, Alessandra Maroni, Anastasia Foppoli, Saliha Moutaharrik, Alice Melocchi, Lucia Zema & Andrea Gazzaniga. (2021) Newly designed punch for scored tablets: Evaluation by an expert system based on quality by design. Journal of Drug Delivery Science and Technology 65, pages 102729.
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Srushti Tambe, Divya Jain, Yashvi Agarwal & Purnima Amin. (2021) Hot-melt extrusion: Highlighting recent advances in pharmaceutical applications. Journal of Drug Delivery Science and Technology 63, pages 102452.
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Howard J. Stamato & Omar L. Sprockel. 2019. Chemical Engineering in the Pharmaceutical Industry. Chemical Engineering in the Pharmaceutical Industry 81 118 .
P. Zarmpi, T. Flanagan, E. Meehan, J. Mann & N. Fotaki. (2017) Biopharmaceutical aspects and implications of excipient variability in drug product performance. European Journal of Pharmaceutics and Biopharmaceutics 111, pages 1-15.
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Nabil Souihi, Melanie Dumarey, Håkan Wikström, Pirjo Tajarobi, Magnus Fransson, Olof Svensson, Mats Josefson & Johan Trygg. (2013) A quality by design approach to investigate the effect of mannitol and dicalcium phosphate qualities on roll compaction. International Journal of Pharmaceutics 447:1-2, pages 47-61.
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Melanie Dumarey, Håkan Wikström, Magnus Fransson, Anders Sparén, Pirjo Tajarobi, Mats Josefson & Johan Trygg. (2011) Combining experimental design and orthogonal projections to latent structures to study the influence of microcrystalline cellulose properties on roll compaction. International Journal of Pharmaceutics 416:1, pages 110-119.
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Omar L. Sprockel & Howard J. Stamato. 2010. Chemical Engineering in the Pharmaceutical Industry. Chemical Engineering in the Pharmaceutical Industry 727 755 .
Y. Takeuchi, M. Yoshida, A. Ito & H. Sunada. (2009) Uniformity of drug content during pharmaceutical dry granulating by roller compaction and tableting processes. Journal of Drug Delivery Science and Technology 19:2, pages 119-124.
Crossref
Garnet Peck, Josephine Soh & Kenneth Morris. 2008. Pharmaceutical Dosage Forms - Tablets. Pharmaceutical Dosage Forms - Tablets 303 336 .
Garnet Peck, Josephine Soh & Kenneth Morris. 2008. Pharmaceutical Dosage Forms - Tablets, Third Edition. Pharmaceutical Dosage Forms - Tablets, Third Edition 303 336 .
Anthony J. Hlinak, Kamal Kuriyan, Kenneth R. Morris, Gintaras V. Reklaitis & Prabir K. Basu. (2006) Understanding critical material properties for solid dosage form design. Journal of Pharmaceutical Innovation 1:1, pages 12-17.
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Thibaut Lecompte, Pierre Doremus, Gérard Thomas, Laurent Perier-Camby, Jean-Claude Le Thiesse, Jean-Claude Masteau & Laurent Debove. (2005) Dry granulation of organic powders—dependence of pressure 2D-distribution on different process parameters. Chemical Engineering Science 60:14, pages 3933-3940.
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Peter Kleinebudde. (2004) Roll compaction/dry granulation: pharmaceutical applications. European Journal of Pharmaceutics and Biopharmaceutics 58:2, pages 317-326.
Crossref
B Rambali, L Baert, E Jans & D.L Massart. (2001) Influence of the roll compactor parameter settings and the compression pressure on the buccal bio-adhesive tablet properties. International Journal of Pharmaceutics 220:1-2, pages 129-140.
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