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Research Article

Chitin and Chitosan as Disintegrants in Paracetamol Tablets

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Pages 2109-2134 | Published online: 20 Oct 2008

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Fengzhi Xu, Tianqi Zhao, Shurong Wang, Songfeng Liu, Ting Yang, Zhanfeng Li, Hongyan Wang & Xuejun Cui. (2016) Preparation of magnetic and pH-responsive chitosan microcapsules via sonochemical method. Journal of Microencapsulation 33:2, pages 191-198.
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Alvaro Goyanes, Consuelo Souto & Ramón Martínez-Pacheco. (2013) Chitosan–kaolin coprecipitate as disintegrant in microcrystalline cellulose-based pellets elaborated by extrusion–spheronization. Pharmaceutical Development and Technology 18:1, pages 137-145.
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H. Goel, A. Arora, A. K. Tiwary & V. Rana. (2011) Development and evaluation of mathematical model to predict disintegration time of fast disintegrating tablets using powder characteristics. Pharmaceutical Development and Technology 16:1, pages 57-64.
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Dakshinamurthy Devanga Chinta, Richard A. Graves, Sarala Pamujula, Natalie Praetorius, Levon A. Bostanian & Tarun K. Mandal. (2009) Spray-Dried Chitosan as a Direct Compression Tableting Excipient. Drug Development and Industrial Pharmacy 35:1, pages 43-48.
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Musa El-Barghouthi, Ala'a Eftaiha, Iyad Rashid, Mayyas Al-Remawi & Adnan Badwan. (2008) A Novel Superdisintegrating Agent Made from Physically Modified Chitosan with Silicon Dioxide. Drug Development and Industrial Pharmacy 34:4, pages 373-383.
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Ashmitha P. Munasur, Viness Pillay, Yahya E. Choonara, Irene Mackraj & Thirumala Govender. (2008) Comparing the Mucoadhesivity and Drug Release Mechanisms of Various Polymer-Containing Propranolol Buccal Tablets. Drug Development and Industrial Pharmacy 34:2, pages 189-198.
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Yogesh M. Rane, Rajshree C. Mashru, Mayur G. Sankalia, Vijay B. Sutariya,Punit P. Shah. (2007) Investigations on Factors Affecting Chitosan for Dissolution Enhancement of Oxcarbazepine by Spray Dried Microcrystal Formulation With an Experimental Design Approach. Drug Development and Industrial Pharmacy 33:9, pages 1008-1023.
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Garnpimol C. Ritthidej & Thawatchai Phaechamud. (2003) Effect of Anionic Water-Soluble Dyes on Film Coating Properties of Chitosan Acetate. Drug Development and Industrial Pharmacy 29:5, pages 585-594.
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KAILASH C. GUPTA & MAJETI N. V. RAVI KUMAR. (2000) An Overview on Chitin and Chitosan Applications with an Emphasis on Controlled Drug Release Formulations. Journal of Macromolecular Science, Part C 40:4, pages 273-308.
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Gabriela Diniz Fonsêca, Arthur Sérgio Avelino de Medeiros, Ednaldo Gomes do Nascimento, Lucas Amaral-Machado, Wógenes Nunes de Oliveira, Maxciara Agda Vicente Pereira, Arnóbio Antônio da Silva Júnior, Waldenice de Alencar Morais & Kátia Solange Cardoso Rodrigues dos Santos. (2020) Development and Validation of Spectrophotometric Method for Propranolol Quantification in Capsule Formulation Containing Chitosan as Pharmaceutical Excipient. Journal of Analytical Chemistry 75:2, pages 184-191.
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Suha M. Dadou, Musa I. El-Barghouthi, Milan D. Antonijevic, Babur Z. Chowdhry & Adnan A. Badwan. (2019) Elucidation of the Controlled-Release Behavior of Metoprolol Succinate from Directly Compressed Xanthan Gum/Chitosan Polymers: Computational and Experimental Studies. ACS Biomaterials Science & Engineering 6:1, pages 21-37.
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Mohammad Chaheen, Noelia M. Sanchez-Ballester, Bernard Bataille, Ahmad Yassine, Emmanuel Belamie & Tahmer Sharkawi. (2018) Development of Coprocessed Chitin-Calcium Carbonate as Multifunctional Tablet Excipient for Direct Compression. Journal of Pharmaceutical Sciences 107:8, pages 2152-2159.
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Emmanuel O. Olorunsola, Grace A. Akpan & Michael U. Adikwu. (2017) Evaluation of Chitosan-Microcrystalline Cellulose Blends as Direct Compression Excipients. Journal of Drug Delivery 2017, pages 1-8.
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Zhe Li, LiJie Zhao, Xiao Lin, Lan Shen & Yi Feng. (2017) Direct compaction: An update of materials, trouble-shooting, and application. International Journal of Pharmaceutics 529:1-2, pages 543-556.
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O. Olorunsola Emmanuel, O. Uwah Timma, J. Olayemi Olubunmi & B. Etukudo Unyime. (2016) Ex-vivo evaluation of crab shell chitosan as absorption enhancer in ciprofloxacin tablet formulation. African Journal of Biotechnology 15:36, pages 1930-1935.
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Jana Sougata, Arijit Gandhi & Subrata Jana. 2016. Marine Glycobiology. Marine Glycobiology 207 225 .
Priti Girotra & Shailendra Kumar Singh. 2015. Handbook of Polymers for Pharmaceutical Technologies. Handbook of Polymers for Pharmaceutical Technologies 33 60 .
Giuseppina Sandri, Silvia Rossi, Franca Ferrari, Maria Cristina Bonferoni & Carla M. Caramella. 2015. Oral Mucosal Drug Delivery and Therapy. Oral Mucosal Drug Delivery and Therapy 53 88 .
Hitesh Verma, Surajpal Verma, Shyam Baboo Prasad & Harmanpreet Singh. (2014) Sublingual Delivery of Frovatriptan: An Indication of Potential Alternative Route. International Scholarly Research Notices 2014, pages 1-9.
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Sougata Jana, Arijit Gandhi, Kalyan Sen & Sanat Basu. 2013. Chitin and Chitosan Derivatives. Chitin and Chitosan Derivatives 337 360 .
Yue Li, Lianzhong Ai, Wallace Yokoyama, Charles F. Shoemaker, Dong Wei, Jianguo Ma & Fang Zhong. (2013) Properties of Chitosan-Microencapsulated Orange Oil Prepared by Spray-Drying and Its Stability to Detergents. Journal of Agricultural and Food Chemistry 61:13, pages 3311-3319.
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Amol S Shete, Adhikrao V Yadav & Srinivasa M Murthy. (2012) Chitosan and chitosan chlorhydrate based various approaches for enhancement of dissolution rate of carvedilol. DARU Journal of Pharmaceutical Sciences 20:1.
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Ziya Bayrak, Cetin Tas, Umut Tasdemir, Halil Erol, Cansel Kose Ozkan, Ayhan Savaser & Yalcin Ozkan. (2011) Formulation of zolmitriptan sublingual tablets prepared by direct compression with different polymers: In vitro and in vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics 78:3, pages 499-505.
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Viviana García Mir, Jyrki Heinämäki, Osmo Antikainen, Antonio Iraizoz Colarte, Sari Airaksinen, Milja Karjalainen, Ofelia Bilbao Revoredo, Olga Maria Nieto & Jouko Yliruusi. (2011) Effects of moisture on tablet compression of chitin. Carbohydrate Polymers 86:2, pages 477-483.
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Viviana García Mir, Jyrki Heinämäki, Osmo Antikainen, Niklas Sandler, Ofelia Bilbao Revoredo, Antonio Iraizoz Colarte, Olga Maria Nieto & Jouko Yliruusi. (2010) Application of Crustacean Chitin as a Co-diluent in Direct Compression of Tablets. AAPS PharmSciTech 11:1, pages 409-415.
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Iyad Rashid, Nidal Daraghmeh, Mayyas Al-Remawi, Stephen A. Leharne, Babur Z. Chowdhry & Adnan Badwan. (2009) Characterization of chitin–metal silicates as binding superdisintegrants. Journal of Pharmaceutical Sciences 98:12, pages 4887-4901.
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Honey GOEL, Nishant VORA, Ashok K. TIWARY & Vikas RANA. (2009) Formulation of Orodispersible Tablets of Ondansetron HCl: Investigations Using Glycine-Chitosan Mixture as Superdisintegrant. YAKUGAKU ZASSHI 129:5, pages 513-521.
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Sengodan Gurusamy Vijaya Kumar & Dina Nath Mishra. (2006) Preparation, Characterization and in Vitro Dissolution Studies of Solid Systems of Valdecoxib with Chitosan. Chemical and Pharmaceutical Bulletin 54:8, pages 1102-1106.
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S.M. van der Merwe, J.C. Verhoef, J.H.M. Verheijden, A.F. Kotzé & H.E. Junginger. (2004) Trimethylated chitosan as polymeric absorption enhancer for improved peroral delivery of peptide drugs. European Journal of Pharmaceutics and Biopharmaceutics 58:2, pages 225-235.
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Naima Zerrouk, Natascia Mennini, Francesca Maestrelli, Chantal Chemtob & Paola Mura. (2004) Comparison of the effect of chitosan and polyvinylpyrrolidone on dissolution properties and analgesic effect of naproxen. European Journal of Pharmaceutics and Biopharmaceutics 57:1, pages 93-99.
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Paola Mura, Naima Zerrouk, Natascia Mennini, Francesca Maestrelli & Chantal Chemtob. (2003) Development and characterization of naproxen–chitosan solid systems with improved drug dissolution properties. European Journal of Pharmaceutical Sciences 19:1, pages 67-75.
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Xin-Yuan Shi & Tian-Wei Tan. (2002) Preparation of chitosan/ethylcellulose complex microcapsule and its application in controlled release of Vitamin D2. Biomaterials 23:23, pages 4469-4473.
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Majeti N. V. Ravi Kumar, Neeraj Kumar, A. J. Domb & Meenakshi Arora. 2002. Filled Elastomers Drug Delivery Systems. Filled Elastomers Drug Delivery Systems 45 117 .
Majeti N.V Ravi Kumar. (2000) A review of chitin and chitosan applications. Reactive and Functional Polymers 46:1, pages 1-27.
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