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Drug Development and Industrial Pharmacy Volume 22, 1996 - Issue 2
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Research Article

1-Alkylcarbonyl-5-fluorouracil Prodrugs: Synthesis, Thermal and Hydrolytic Stability

H. D. Beall Department of Medicinal Chemistry, University of Florida, P. O. Box 100485, Gainesville, Florida, 32610
,
R. J. Prankerd Department of Pharmaceutics, University of Florida, Gainesville, Florida, 32610
&
K. B. Sloan Department of Medicinal Chemistry, University of Florida, P. O. Box 100485, Gainesville, Florida, 32610
Pages 85-90 | Published online: 20 Oct 2008

Citations (9)

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Read on this site (1)

H. D. Beall, R. J. Prankerd & K. B. Sloan. (1997) 1,3-Bisalkylcarbonyl- and 3-Alkylcarbonyl-5-fluorouracil Prodrugs: Syntheses, Thermal, and Hydrolytic Stability. Drug Development and Industrial Pharmacy 23:6, pages 517-525.
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Articles from other publishers (8)

Kenneth Sloan, Scott C. Wasdo & Susruta Majumdar. 2010. Prodrugs and Targeted Delivery. Prodrugs and Targeted Delivery 153 179 .
Victor R. Guarino & Valentino J. Stella. 2007. Prodrugs. Prodrugs 833 887 .
. (2005) Preparation and Evaluation of Sold Lipid Nanoparticles(SLNs) containing 5-Fluorouracil and Its Derivative. Journal of Korean Pharmaceutical Sciences 35:3, pages 143-150.
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Kenneth B. Sloan & Scott Wasdo. (2003) Designing for topical delivery: Prodrugs can make the difference. Medicinal Research Reviews 23:6, pages 763-793.
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Lolita Caram, Mech Doeleman, William J. Roberts, Richard J. Prankerd, John H. Perrin, William J. Underberg & Kenneth B. Sloan. (2009) Synthesis of 1‐ and 3‐arylcarbonyl derivatives of 5‐fluorouracil. Journal of Heterocyclic Chemistry 36:2, pages 397-401.
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H. Elizabeth Taylor & Kenneth B. Sloan. (1998) 1-Alkylcarbonyloxymethyl Prodrugs of 5-Fluorouracil (5-FU): Synthesis, Physicochemical Properties, and Topical Delivery of 5-FU. Journal of Pharmaceutical Sciences 87:1, pages 15-20.
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Ana I Patrick, Howard D Beall, Patricia Gilroy & Kenneth B Sloan. (1997) Effect of vehicles on topical delivery of 5-fluorouracil (5FU) by 1-acyl-5FU prodrugs. International Journal of Pharmaceutics 154:1, pages 39-48.
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Howard D. Beall & Kenneth B. Sloan. (1996) Transdermal delivery of 5-fluorouracil (5-FU) by 1-alkylcarbonyl-5-FU prodrugs. International Journal of Pharmaceutics 129:1-2, pages 203-210.
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