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ORIGINAL ARTICLEClinical Translational Therapeutics

Downregulation of N-cadherin Expression Inhibits Invasiveness, Arrests Cell Cycle and Induces Cell Apoptosis in Esophageal Squamous Cell Carcinoma

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Pages 479-486 | Published online: 16 Dec 2009

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Yunwei Ou, Liying Ma, Ling Ma, Zhen Huang, Wei Zhou, Chunling Zhao, Bailin Zhang, Yongmei Song, Chunjiang Yu & Qimin Zhan. (2013) Overexpression of cyclin B1 antagonizes chemotherapeutic-induced apoptosis through PTEN/Akt pathway in human esophageal squamous cell carcinoma cells. Cancer Biology & Therapy 14:1, pages 45-55.
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Zhan-Qi Cao, Zhi Wang & Ping Leng. (2019) Aberrant N-cadherin expression in cancer. Biomedicine & Pharmacotherapy 118, pages 109320.
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Shengtao Zhu, Juan Liu, Li Min, Xiujing Sun, Qingdong Guo, Hengcun Li, Zheng Zhang, Yu Zhao, Junchao Gu & Shutian Zhang. (2018) Cadherin Expression Shift Could Well Distinguish Esophageal Squamous Cell Carcinoma from Non- Cancerous Esophageal Tissues. Oncology Research and Treatment 41:6, pages 380-385.
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Krzysztof M. Mrozik, Chee Man Cheong, Duncan Hewett, Annie W.S. Chow, Orest W. Blaschuk, Andrew C.W. Zannettino & Kate Vandyke. (2015) Therapeutic targeting of N-cadherin is an effective treatment for multiple myeloma. British Journal of Haematology 171:3, pages 387-399.
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M J D Prins, J P Ruurda, M P Lolkema, R Sitarz, F J W ten Kate & R van Hillegersberg. (2015) The role of biological markers of epithelial to mesenchymal transition in oesophageal adenocarcinoma, an immunohistochemical study. Journal of Clinical Pathology 68:7, pages 529-535.
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E. Mato, C. Gonzalez, A. Moral, J. I. Perez, O. Bell, E. Lerma & A. de Leiva. (2014) ABCG2/BCRP gene expression is related to epithelial-mesenchymal transition inducer genes in a papillary thyroid carcinoma cell line (TPC-1). Journal of Molecular Endocrinology 52:3, pages 289-300.
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TAKESHI KAJIWARA, YOICHI HIASA, TOMOHIRO NISHINA, TOSHIHIKO MATSUMOTO, SHINICHIRO HORI, SEIJIN NADANO, HARUO IGUCHI, SATORU TAKEJI, EIJI TSUBOUCHI, YOSHIO IKEDA & MORIKAZU ONJI. (2014) Maximum standardized uptake value in 18F-fluoro-2-deoxyglucose positron emission tomography is associated with advanced tumor factors in esophageal cancer. Molecular and Clinical Oncology 2:2, pages 313-321.
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Jingkun Zhao, Pu Li, Hao Feng, Puxiongzhi Wang, Yaping Zong, Junjun Ma, Zhuo Zhang, Xuehua Chen, Minhua Zheng, Zhenggang Zhu & Aiguo Lu. (2013) Cadherin-12 contributes to tumorigenicity in colorectal cancer by promoting migration, invasion, adhersion and angiogenesis. Journal of Translational Medicine 11:1.
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Xinbing Sui, Da Wang, Shumin Geng, Gongli Zhou, Chao He & Xiaotong Hu. (2011) Methylated promoters of genes encoding protocadherins as a new cancer biomarker family. Molecular Biology Reports 39:2, pages 1105-1111.
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Qi-min Zhan, Lu-hua Wang, Yong-mei Song, Yun-wei Ou, Jing Jiang, Jing Fan, Jing-bo Wang & Jie Shen. 2012. Recent Advances in Cancer Research and Therapy. Recent Advances in Cancer Research and Therapy 493 534 .
Géraldine Parnaud, Carmen Gonelle-Gispert, Philippe Morel, Laurianne Giovannoni, Yannick D. Muller, Raphael Meier, Sophie Borot, Thierry Berney & Domenico Bosco. (2011) Cadherin Engagement Protects Human β-Cells from Apoptosis. Endocrinology 152:12, pages 4601-4609.
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Gerhard F Huber, Lena Züllig, Alex Soltermann, Matthias Roessle, Nicole Graf, Stephan K Haerle, Gabriela Studer, Wolfram Jochum, Holger Moch & Sandro J Stoeckli. (2011) Down regulation of E-Cadherin (ECAD) - a predictor for occult metastatic disease in sentinel node biopsy of early squamous cell carcinomas of the oral cavity and oropharynx. BMC Cancer 11:1.
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Arun Kumar Nalla, Norman Estes, Jitendra Patel & Jasti S. Rao. (2011) N-cadherin mediates angiogenesis by regulating monocyte chemoattractant protein-1 expression via PI3K/Akt signaling in prostate cancer cells. Experimental Cell Research 317:17, pages 2512-2521.
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Santosh Kumar Patnaik, Eric Kannisto, Reema Mallick & Sai Yendamuri. (2011) Overexpression of the Lung Cancer-Prognostic miR-146b MicroRNAs Has a Minimal and Negative Effect on the Malignant Phenotype of A549 Lung Cancer Cells. PLoS ONE 6:7, pages e22379.
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