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Cancer Investigation Volume 28, 2010 - Issue 8
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ORIGINAL ARTICLEClinical Translational Therapeutics

Weekly Chemotherapy with Cisplatin and Paclitaxel and Concurrent Radiation Therapy as Preoperative Treatment in Locally Advanced Esophageal Cancer: A Phase II Study

Michele OrdituraDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Gennaro GaliziaDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Vincenzo NapolitanoDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Erika MartinelliDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Roberto PacelliDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Eva LietoDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Gaetano AurilioDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
,
Loredana VecchioneDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Floriana MorgilloDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Giuseppe CatalanoDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Fortunato CiardielloDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Alberto Del GenioDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Natale Di MartinoDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
&
Ferdinando De VitaDivision of Medical Oncology, Division of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery “F. Magrassi e A. Lanzara”, Second University of Naples, School of Medicine, Naples, Italy, Division of Radiotherapy, Federico II University of Naples, School of Medicine, Naples, Italy
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Pages 820-827 | Published online: 18 May 2010

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Emad Elquza, Hani M. Babiker, Krisha J. Howell, Andrew I. Kovoor, Thomas David Brown, Hitendra Patel, Steven A. Malangone, Mitesh J. Borad & Tomislav Dragovich. (2016) Phase I Study of Concomitant Pemetrexed and Cisplatin Plus External Beam Radiation Therapy in Patients with Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Carcinomas. Cancer Investigation 34:2, pages 57-63.
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Articles from other publishers (12)

T. Song, D. Du, X. Zhang, M. Fang & S. Wu. (2017) Comparative study of radiotherapy plus erlotinib versus chemoradiotherapy for elderly patients with esophageal cancer: a propensity score-matched analysis. Diseases of the Esophagus 30:9, pages 1-10.
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Min Fang, Tao Song, Xiaodong Liang, Shiliang Lv, Jianbo Li, Hong’en Xu, Limin Luo & Yongshi Jia. (2017) Comparative study of cisplatin-based definitive concurrent chemoradiotherapy with S-1 versus paclitaxel for unresectable locally advanced esophageal squamous cell carcinoma. Oncotarget 8:23, pages 37080-37090.
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Lihong Cong & Likuan Hu. (2017) The value of the combination of hemoglobin, albumin, lymphocyte and platelet in predicting platinum-based chemoradiotherapy response in male patients with esophageal squamous cell carcinoma. International Immunopharmacology 46, pages 75-79.
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Bianca So, Loredana Marcu, Ian Olver, Raghu Gowda & Eva Bezak. (2017) Oesophageal cancer: Which treatment is the easiest to swallow? A review of combined modality treatments for resectable carcinomas. Critical Reviews in Oncology/Hematology 113, pages 135-150.
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Hua-Rong Tang, Hai-Feng Ma, Shi-Min An, Harun Badakhshi, Jia-Ying Deng, Jun-Hua Zhang, Yun Chen, Zhen Zhang, Xiao-Mao Guo, Guo-Liang Jiang & Kuai-Le Zhao. (2016) A Phase II Study of Concurrent Chemoradiotherapy With Paclitaxel and Cisplatin for Inoperable Esophageal Squamous Cell Carcinoma. American Journal of Clinical Oncology 39:4, pages 350-354.
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Bin Yao, Bingxu Tan, Cong Wang, Qingxu Song, Jianbo Wang, Shanghai Guan, Yibin Jia, Yanan Ma, Xiaochen Huang, Yi Sun & Yufeng Cheng. (2016) Comparison of Definitive Chemoradiotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma. Annals of Surgical Oncology 23:7, pages 2367-2372.
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Guang-Yu Tian, Min Miu & Xin-En Huang. (2014) Systematic Analysis of Pemetrexed-based Chemoradiotherapy for Patients with Locally Advanced or Metastatic Esophageal Cancer. Asian Pacific Journal of Cancer Prevention 15:19, pages 8475-8478.
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Lingli Tu, Lan Sun, Yong Xu, Yongsheng Wang, Lin Zhou, Yongmei Liu, Jiang Zhu, Feng Peng, Yuquan Wei & Youling Gong. (2013) Paclitaxel and cisplatin combined with intensity-modulated radiotherapy for upper esophageal carcinoma. Radiation Oncology 8:1.
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Felice Pasini, Giovanni de Manzoni, Andrea Zanoni, Antonio Grandinetti, Carlo Capirci, Michele Pavarana, Anna Tomezzoli, Domenico Rubello & Claudio Cordiano. (2013) Neoadjuvant therapy with weekly docetaxel and cisplatin, 5-fluorouracil continuous infusion, and concurrent radiotherapy in patients with locally advanced esophageal cancer produced a high percentage of long-lasting pathological complete response. Cancer 119:5, pages 939-945.
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Ming Gu, Su-Yi Li, Xin-En Huang, Yan Lin, Hong-Yan Cheng & Lin Liu. (2012) A Phase II Study on Continuous Infusional Paclitaxel and 5-Fu as First-line Chemotherapy for Patients with Advanced Esophageal Cancer. Asian Pacific Journal of Cancer Prevention 13:11, pages 5587-5591.
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M. Orditura, G. Galizia, F. Morgillo, E. Martinelli, E. Lieto, F. Vitiello, N. Di Martino, R. Pacelli, A. Renda, F. Ciardiello & F. De Vita. (2012) Complete response to preoperative chemoradiation and survival in esophageal cancer: a pooled analysis of three single-institution phase II trials. Diseases of the Esophagus 25:2, pages 130-136.
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F De Vita, M Orditura, E Martinelli, L Vecchione, R Innocenti, V C Sileni, C Pinto, M Di Maio, A Farella, T Troiani, F Morgillo, V Napolitano, E Ancona, N Di Martino, A Ruol, G Galizia, A Del Genio & F Ciardiello. (2011) A multicenter phase II study of induction chemotherapy with FOLFOX-4 and cetuximab followed by radiation and cetuximab in locally advanced oesophageal cancer. British Journal of Cancer 104:3, pages 427-432.
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