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ORIGINAL ARTICLE: CLINICAL TRANSLATIONAL THERAPEUTICS

Expression of the Forkhead Transcription Factor FOXP1 is Associated with Tumor Grade and Ki67 Expression in Clear Cell Renal Cell Carcinoma

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Pages 123-129 | Published online: 06 Jan 2011

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Tian Zhang, Sarabjot Pabla, Felicia L. Lenzo, Jeffrey M. Conroy, Mary K. Nesline, Sean T. Glenn, Antonios Papanicolau-Sengos, Blake Burgher, Vincent Giamo, Jonathan Andreas, Yirong Wang, Wiam Bshara, Katherine G. Madden, Keisuke Shirai, Konstantin Dragnev, Laura J. Tafe, Rajan Gupta, Jason Zhu, Matthew Labriola, Shannon McCall, Daniel J. George, Pooja Ghatalia, Farshid Dayyani, Robert Edwards, Michelle S Park, Rajbir Singh, Robin Jacob, Saby George, Bo Xu, Matthew Zibelman, Razelle Kurzrock & Carl Morrison. (2020) Proliferative potential and response to nivolumab in clear cell renal cell carcinoma patients. OncoImmunology 9:1.
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Zhun Wang, Hui Xie, Linpei Guo, Qiliang Cai, Zhiqun Shang, Ning Jiang & Yuanjie Niu. (2017) Prognostic and clinicopathological value of Ki-67/MIB-1 expression in renal cell carcinoma: a meta-analysis based on 4579 individuals. Cancer Management and Research 9, pages 679-689.
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Sumaiah I. Hussein, Amal Y. Al-Yasiri, Heba F. Hassan, Basim M. Kashman & Rasha A. Azeez. (2023) Immunohistochemistry technique for effect of gold nanoparticles, laser, and photodynamic therapy on FoxP1 level in infected mice with mammary adenocarcinoma. Lasers in Medical Science 38:1.
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Tarek Mohamed Kamal Motawi, Dina Sabry, Nagwa Ibrahim Shehata, Mira Magdy William & Atef Tadros Fahim. (2021) Impact of FOXP1 rs2687201 genetic variant on the susceptibility to HCV‐related hepatocellular carcinoma in Egyptians. Journal of Biochemical and Molecular Toxicology 36:3.
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Jinbo Song, Zhe Yu, Bingqi Dong, Mingkai Zhu, Xiaofeng Guo, Yongkang Ma, Shiming Zhao & Tiejun Yang. (2021) Clinical significance of circulating tumour cells and Ki-67 in renal cell carcinoma. World Journal of Surgical Oncology 19:1.
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Giovanni Cochetti, Luigi Cari, Giuseppe Nocentini, Vincenza Maulà, Chiara Suvieri, Rosy Cagnani, Jacopo Adolfo Rossi De Vermandois & Ettore Mearini. (2020) Detection of urinary miRNAs for diagnosis of clear cell renal cell carcinoma. Scientific Reports 10:1.
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Tuba DEVRİM & Mahi BALCI. (2020) COEXISTENCE OF CD44 AND KI-67 AS THE PROGNOSTIC MARKERS IN RENAL CELL CARCINOMARenal Hücreli Karsinomda Prognostik Belirteçler Olarak CD44 ve Ki-67 Birlikteliği. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi 22:1, pages 79-88.
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Heli Xiang, Wujun Xue, Xiaoyan Wu, Jin Zheng, Chenguang Ding, Yang Li & Meng Dou. (2019) FOXP1 inhibits high glucose-induced ECM accumulation and oxidative stress in mesangial cells. Chemico-Biological Interactions 313, pages 108818.
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Fan Zhang, Xin Ma, Hongzhao Li, Yu Zhang, Xintao Li, Luyao Chen, Gang Guo, Yu Gao, Liangyou Gu, Yongpeng Xie, Junyao Duan & Xu Zhang. (2018) FOXK2 suppresses the malignant phenotype and induces apoptosis through inhibition of EGFR in clear-cell renal cell carcinoma. International Journal of Cancer 142:12, pages 2543-2557.
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Maria Jesus Herrero & Yorick Gitton. (2018) The untold stories of the speech gene, the FOXP2 cancer gene. Genes & Cancer 9:1-2, pages 11-38.
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Hanjun Li, Pei Liu, Shuqin Xu, Yinghua Li, Joseph D. Dekker, Baojie Li, Ying Fan, Zhenlin Zhang, Yang Hong, Gong Yang, Tingting Tang, Yongxin Ren, Haley O. Tucker, Zhengju Yao & Xizhi Guo. (2017) FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging. Journal of Clinical Investigation 127:4, pages 1241-1253.
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Sevil Oskay Halacli. (2017) FOXP1 enhances tumor cell migration by repression of NFAT1 transcriptional activity in MDA-MB-231 cells. Cell Biology International 41:1, pages 102-110.
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Yali Song, Xiaoling Li, Zhaoyang Zeng, Qiao Li, Zhaojian Gong, Qianjin Liao, Xiayu Li, Pan Chen, Bo Xiang, Wenling Zhang, Fang Xiong, Yanhong Zhou, Ming Zhou, Jian Ma, Yong Li, Xiang Chen, Guiyuan Li & Wei Xiong. (2016) Epstein-Barr virus encoded miR-BART11 promotes inflammation-induced carcinogenesis by targeting FOXP1. Oncotarget 7:24, pages 36783-36799.
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Eun Jung Choi, Eun Jin Seo, Dae Kyoung Kim, Su In Lee, Yang Woo Kwon, Il Ho Jang, Ki-Hyung Kim, Dong-Soo Suh & Jae Ho Kim. (2015) FOXP1 functions as an oncogene in promoting cancer stem cell-like characteristics in ovarian cancer cells. Oncotarget 7:3, pages 3506-3519.
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Xia Yan, Huiling Zhou, Tingting Zhang, Pan Xu, Shusen Zhang, Wei Huang, Linlin Yang, Xingxing Gu, Runzhou Ni & Tianyi Zhang. (2015) Downregulation of FOXP2 promoter human hepatocellular carcinoma cell invasion. Tumor Biology 36:12, pages 9611-9619.
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Anna S. Berghoff, Aysegül Ilhan-Mutlu, Carina Dinhof, Manuel Magerle, Monika Hackl, Georg Widhalm, Johannes A. Hainfellner, Karin Dieckmann, Josef Pichler, Markus Hutterer, Thomas Melchardt, Rupert Bartsch, Christoph C. Zielinski, Peter Birner & Matthias Preusser. (2015) Differential role of angiogenesis and tumour cell proliferation in brain metastases according to primary tumour type: analysis of 639 cases. Neuropathology and Applied Neurobiology 41:2, pages e41-e55.
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Liancheng Zhu, Zhenhua Hu, Juanjuan Liu, Jian Gao & Bei Lin. (2014) Gene expression profile analysis identifies metastasis and chemoresistance-associated genes in epithelial ovarian carcinoma cells. Medical Oncology 32:1.
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LIANG XUE, SHUYUAN YUE & JIANNING ZHANG. (2014) FOXP1 has a low expression in human gliomas and its overexpression inhibits proliferation, invasion and migration of human glioma U251 cells. Molecular Medicine Reports 10:1, pages 467-472.
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Eric W.-F. Lam, Jan J. Brosens, Ana R. Gomes & Chuay-Yeng Koo. (2013) Forkhead box proteins: tuning forks for transcriptional harmony. Nature Reviews Cancer 13:7, pages 482-495.
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Judy Yan & Damu Tang. 2013. Proteins of the Nucleolus. Proteins of the Nucleolus 275 304 .
Jian Feng, Xuesong Zhang, Huijun Zhu, Xudong Wang, Songshi Ni & Jianfei Huang. (2012) High Expression of FoxP1 Is Associated With Improved Survival in Patients With Non–Small Cell Lung Cancer. American Journal of Clinical Pathology 138:2, pages 230-235.
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