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Cancer Investigation Volume 29, 2011 - Issue 6
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ORIGINAL ARTICLE: CAUSATION AND PREVENTION

Association of Functionally Important Polymorphism of Microsomal Epoxide Hydrolase Gene (EPHX1) With Lung Cancer Susceptibility

Anup R. TilakEnvironmental Biotechnology Section, Indian Institute of Toxicology Research (IITR) (Formerly Industrial Toxicology Research Centre), M.G. Marg, Lucknow-226001, Uttar Pradesh, India,
,
Sachin KumarDepartment of Medicine, All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi-110029, India,
,
Meenu JainDepartment of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Raibareilly Road, Lucknow-226014, Uttar Pradesh, India,
,
Mohan C. PantDepartment of Radiotherapy, CSJM Medical University, Chowk, Lucknow-226003, Uttar Pradesh, India,
,
Bhudev C. DasDepartment of Molecular Oncology, Institute of Cytology & Preventive Oncology (ICPO), Sector-39, NOIDA-201301, Uttar Pradesh, India,
,
Randeep GuleriaDepartment of Medicine, All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi-110029, India,
,
Balraj MittalDepartment of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Raibareilly Road, Lucknow-226014, Uttar Pradesh, India,
,
Neeraj MathurEpidemiology Section, Indian Institute of Toxicology Research (IITR) (Formerly Industrial Toxicology Research Centre), M.G. Marg, Lucknow-226001, Uttar Pradesh, India
&
Ashwani KumarEnvironmental Biotechnology Section, Indian Institute of Toxicology Research (IITR) (Formerly Industrial Toxicology Research Centre), M.G. Marg, Lucknow-226001, Uttar Pradesh, India,Correspondence[email protected]
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Pages 411-418 | Published online: 07 Jun 2011

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Shanbeh Zienolddiny & Vidar Skaug. (2012) Single nucleotide polymorphisms as susceptibility, prognostic, and therapeutic markers of nonsmall cell lung cancer. Lung Cancer: Targets and Therapy 3, pages 1-14.
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Articles from other publishers (15)

Harleen Kaur Walia, Navneet Singh & Siddharth Sharma. (2021) Genetic polymorphisms in the mEH  gene in relation to tobacco smoking: role in lung cancer susceptibility and survival in north Indian patients with lung cancer undergoing platinum-based chemotherapy . Future Oncology 17:35, pages 4925-4946.
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Guanqun Ju, Bing Liu, Mingfei Ji, Rui Jin, Xiaojian Xu, Yongshuang Xiao, Jie Li, Dongliang Xu, Yuhua Huang & Jianquan Hou. (2021) Folic Acid–Modified miR-491-5p–Loaded ZIF-8 Nanoparticles Inhibit Castration-Resistant Prostate Cancer by Regulating the Expression of EPHX1. Frontiers in Bioengineering and Biotechnology 9.
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Sheikh M. Shaffi. 2021. Genetic Polymorphism and cancer susceptibility. Genetic Polymorphism and cancer susceptibility 319 339 .
Jing Tao, Nana Li, Zhen Liu, Ying Deng, Xiaohong Li, Ming Chen, Jing Yu, Jun Zhu, Ping Yu & Yanping Wang. (2019) The effect on congenital heart diseases of maternal EPHX1 polymorphisms modified by polycyclic aromatic hydrocarbons exposure. Medicine 98:30, pages e16556.
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Debmalya Sengupta, Udayan Guha, Samsiddhi Bhattacharjee & Mainak Sengupta. (2017) Association of 12 polymorphic variants conferring genetic risk to lung cancer in Indian population: An extensive meta-analysis. Environmental and Molecular Mutagenesis 58:9, pages 688-700.
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Wei Yu, Zhi Lin & Baolin Qu. (2014) Impact of Epoxide Hydrolase 1 Polymorphisms on Lung Cancer Susceptibility in Asian Populations. Cell Biochemistry and Biophysics 71:2, pages 813-820.
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Xiaoqin Yang, Yubing Wang & Guiping Wang. (2014) Quantitative assessment of the influence of EPHX1 gene polymorphisms and cancer risk: a meta-analysis with 94,213 subjects. Journal of Experimental & Clinical Cancer Research 33:1.
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Mona Fathy, Mai Hamed, Omnia Youssif, Nahla Fawzy & Wafa Ashour. (2013) Association Between Environmental Tobacco Smoke Exposure and Lung Cancer Susceptibility: Modification by Antioxidant Enzyme Genetic Polymorphisms. Molecular Diagnosis & Therapy 18:1, pages 55-62.
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Hee Nam Kim, Nan Young Kim, Li Yu, Il-Kwon Lee, Min-Ho Shin, Hee Jo Baek, Hoon Kook & Hyeoung-Joon Kim. (2014) The EPHX1 rs1051740 Polymorphism Is Associated with Childhood Acute Lymphoblastic Leukemia in a Korean Population. Advances in Bioscience and Biotechnology 05:07, pages 678-684.
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Wafa Ashour, Mona Fathy, Mai Hamed, Omnia Youssif & Nahla Fawzy. (2013) Association between environmental tobacco smoke exposure and lung cancer susceptibility: Modification by antioxidant enzymes genetic polymorphisms. Egyptian Journal of Chest Diseases and Tuberculosis 62:4, pages 781-788.
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Siwen Wang, Jie Zhu, Ruxin Zhang, Siyang Wang & Zongheng Gu. (2013) Association between microsomal epoxide hydrolase 1 T113C polymorphism and susceptibility to lung cancer. Tumor Biology 34:2, pages 1045-1052.
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Anup R. TilakSachin KumarMohan C. PantNeeraj MathurAshwani Kumar. (2013) Polymorphism Arg72Pro of p53 Confers Susceptibility to Squamous Cell Carcinoma of Lungs in a North Indian Population . DNA and Cell Biology 32:2, pages 66-72.
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Hong Liu, Hai-Yan Li, Hong-Jie Chen, Yong-Jie Huang, Shao Zhang & Jing Wang. (2012) EPHX1 A139G polymorphism and lung cancer risk: a meta-analysis. Tumor Biology 34:1, pages 155-163.
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Wei Shen, Yi Fang, Aifei Tong & Qing Zhu. (2012) Synthesis and structure–activity relationship of acylthiourea derivatives as inhibitors of microsomal epoxide hydrolase. Medicinal Chemistry Research 21:12, pages 4214-4218.
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Tugba Boyunegmez Tumer, Gurses Sahin & Emel Arinç. (2011) Association between polymorphisms of EPHX1 and XRCC1 genes and the risk of childhood acute lymphoblastic leukemia. Archives of Toxicology 86:3, pages 431-439.
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