269
Views
53
CrossRef citations to date
0
Altmetric
CELLULAR AND MOLECULAR BIOLOGY

Cisplatin Restores TRAIL Apoptotic Pathway in Glioblastoma-Derived Stem Cells through Up-regulation of DR5 and Down-regulation of c-FLIP

, , , , , , , & show all
Pages 511-520 | Published online: 30 Aug 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Sireesha V Garimella, Siri Chandana Gampa & Pankaj Chaturvedi. (2023) Mitochondria in Cancer Stem Cells: From an Innocent Bystander to a Central Player in Therapy Resistance. Stem Cells and Cloning: Advances and Applications 16, pages 19-41.
Read now
Shenxu Wang, Sai Ma, Xiujuan Li, Zengfu Xue, Xiaotian Zhang, Weiwei Fan, Yongzhan Nie, Kaichun Wu, Xiaoyuan Chen & Feng Cao. (2014) Attenuation of lung cancer stem cell tumorigenesis and metastasis by cisplatin. Experimental Lung Research 40:8, pages 404-414.
Read now
Bo Zhang, Hong Shan, Dan Li, Zheng-Ran Li, Kang-Shun Zhu & Zai-Bo Jiang. (2012) The inhibitory effect of MSCs expressing TRAIL as a cellular delivery vehicle in combination with cisplatin on hepatocellular carcinoma. Cancer Biology & Therapy 13:12, pages 1175-1184.
Read now

Articles from other publishers (50)

Shweta Gulia, Prakash Chandra & Asmita Das. (2023) The Prognosis of Cancer Depends on the Interplay of Autophagy, Apoptosis, and Anoikis within the Tumor Microenvironment. Cell Biochemistry and Biophysics 81:4, pages 621-658.
Crossref
Amirhossein Izadpanah, Niloufar Mohammadkhani, Mina Masoudnia, Mahsa Ghasemzad, Arefeh Saeedian, Hamid Mehdizadeh, Mansour Poorebrahim & Marzieh Ebrahimi. (2023) Update on immune‐based therapy strategies targeting cancer stem cells. Cancer Medicine.
Crossref
Paula Alfonso-Triguero, Julia Lorenzo, Ana Paula Candiota, Carles Arús, Daniel Ruiz-Molina & Fernando Novio. (2023) Platinum-Based Nanoformulations for Glioblastoma Treatment: The Resurgence of Platinum Drugs?. Nanomaterials 13:10, pages 1619.
Crossref
Morrent Thang, Clara Mellows, Alison Mercer-Smith, Phuong Nguyen & Shawn Hingtgen. (2023) Current approaches in enhancing TRAIL therapies in glioblastoma. Neuro-Oncology Advances 5:1.
Crossref
Maddalen Otaegi-Ugartemendia, Ander Matheu & Estefania Carrasco-Garcia. (2022) Impact of Cancer Stem Cells on Therapy Resistance in Gastric Cancer. Cancers 14:6, pages 1457.
Crossref
Kamal Shaik Fakiruddin, Moon Nian Lim, Norshariza Nordin, Rozita Rosli & Syahril Abdullah. (2021) Chemo-Sensitization of CD133+ Cancer Stem Cell Enhances the Effect of Mesenchymal Stem Cell Expressing TRAIL in Non-Small Cell Lung Cancer Cell Lines. Biology 10:11, pages 1103.
Crossref
Xiaokun Zhou, Liang Lv, Yuan Tan, Zhongyi Zhang, Shuyang Wei & Shaowen Xiao. (2021) Tanshinone IIA sensitizes TRAIL-induced apoptosis in glioblastoma through inducing the expression of death receptors (and suppressing STAT3 activation). Brain Research 1766, pages 147515.
Crossref
Ehsan Razeghian, Wanich Suksatan, Heshu Sulaiman Rahman, Dmitry O. Bokov, Walid Kamal Abdelbasset, Ali Hassanzadeh, Faroogh Marofi, Mahboubeh Yazdanifar & Mostafa Jarahian. (2021) Harnessing TRAIL-Induced Apoptosis Pathway for Cancer Immunotherapy and Associated Challenges. Frontiers in Immunology 12.
Crossref
Melanie Schwerdtfeger, Vincenzo Desiderio, Sebastian Kobold, Tarik Regad, Silvia Zappavigna & Michele Caraglia. (2021) Long non-coding RNAs in cancer stem cells. Translational Oncology 14:8, pages 101134.
Crossref
Longfei Deng, Xuan Zhai, Ping Liang & Hongjuan Cui. (2021) Overcoming TRAIL Resistance for Glioblastoma Treatment. Biomolecules 11:4, pages 572.
Crossref
Xin Meng, Jinrui Zhang, Hao Wu, Dahai Yu & Xuexun Fang. (2020) Akkermansia muciniphila Aspartic Protease Amuc_1434* Inhibits Human Colorectal Cancer LS174T Cell Viability via TRAIL-Mediated Apoptosis Pathway. International Journal of Molecular Sciences 21:9, pages 3385.
Crossref
Luisa Barbato, Marco Bocchetti, Anna Di Biase & Tarik Regad. (2019) Cancer Stem Cells and Targeting Strategies. Cells 8:8, pages 926.
Crossref
Xun Yuan, Ambikai Gajan, Qian Chu, Hua Xiong, Kongming Wu & Gen Sheng Wu. (2018) Developing TRAIL/TRAIL death receptor-based cancer therapies. Cancer and Metastasis Reviews 37:4, pages 733-748.
Crossref
Luke Humphreys, Margarita Espona‐Fiedler & Daniel B. Longley. (2018) FLIP as a therapeutic target in cancer . The FEBS Journal 285:22, pages 4104-4123.
Crossref
Junfeng Liu, Qinglei Gao, Tao Xie, Yu Liu, Longjun Luo, Cheng Xu, Lu Shen, Feng Wan, Ting Lei & Fei Ye. (2018) Synergistic effect of TRAIL and irradiation in elimination of glioblastoma stem-like cells. Clinical and Experimental Medicine 18:3, pages 399-411.
Crossref
Kamal Shaik Fakiruddin, Nadiah Ghazalli, Moon Lim, Zubaidah Zakaria & Syahril Abdullah. (2018) Mesenchymal Stem Cell Expressing TRAIL as Targeted Therapy against Sensitised Tumour. International Journal of Molecular Sciences 19:8, pages 2188.
Crossref
Gaoxin Lei, Menglong Xu, Zhipan Xu, Chenchen Lu & Shuhua Tan. (2018) Combination of novel DR5 targeting agonistic scFv antibody TR2-3 with cisplatin shows enhanced synergistic antitumor activity in vitro and in vivo. Biomedicine & Pharmacotherapy 98, pages 271-279.
Crossref
Rute Loureiro, Katia A. Mesquita, Silvia Magalhães-Novais, Paulo J. Oliveira & Ignacio Vega-Naredo. (2017) Mitochondrial biology in cancer stem cells. Seminars in Cancer Biology 47, pages 18-28.
Crossref
Jayaprakasam Madhumathi, Surapally Sridevi & Rama Shanker Verma. (2017) CD25 targeted therapy of chemotherapy resistant leukemic stem cells using DR5 specific TRAIL peptide. Stem Cell Research 19, pages 65-75.
Crossref
SEEMA-MARIA NATHWANI, LISA M. GREENE, STEFANIA BUTINI, GIUSEPPE CAMPIANI, D. CLIVE WILLIAMS, AFSHIN SAMALI, EVA SZEGEZDI & DANIELA M. ZISTERER. (2016) The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL-induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells. International Journal of Oncology 49:1, pages 74-88.
Crossref
Zhichao Hao, Xiaojian Han, Xin Sun, Meiying Shen, Jingjing Huang, Yaying Li, Tatsuhiko Ozawa, Da Pang, Shoude Jin, Hiroyuki Kishi, Atsushi Muraguchi & Aishun Jin. (2016) Fully human monoclonal antibodies to TRAIL-R1 enhance TRAIL-induced apoptosis via activation of caspase-8 pathway. Biochemical and Biophysical Research Communications 475:2, pages 238-244.
Crossref
Matheus H.W. Crommentuijn, Casey A. Maguire, Johanna M. Niers, W. Peter Vandertop, Christian E. Badr, Thomas Würdinger & Bakhos A. Tannous. (2016) Intracranial AAV-sTRAIL combined with lanatoside C prolongs survival in an orthotopic xenograft mouse model of invasive glioblastoma. Molecular Oncology 10:4, pages 625-634.
Crossref
Yan Liu, Oriana E. Hawkins, Anna E. Vilgelm, Jeffrey S. Pawlikowski, Jeffrey A. Ecsedy, Jeffrey A. Sosman, Mark C. Kelley & Ann Richmond. (2015) Combining an Aurora Kinase Inhibitor and a Death Receptor Ligand/Agonist Antibody Triggers Apoptosis in Melanoma Cells and Prevents Tumor Growth in Preclinical Mouse Models. Clinical Cancer Research 21:23, pages 5338-5348.
Crossref
Mohammed Elmallah & Olivier Micheau. (2015) Marine Drugs Regulating Apoptosis Induced by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL). Marine Drugs 13:11, pages 6884-6909.
Crossref
Ying‐Hua Wang & David T Scadden. (2015) Harnessing the apoptotic programs in cancer stem‐like cells. EMBO reports 16:9, pages 1084-1098.
Crossref
KIMBERLY A. FOSTER, ESTHER P. JANE, DANIEL R. PREMKUMAR, ALEJANDRO MORALES & IAN F. POLLACK. (2015) NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5. International Journal of Oncology 47:2, pages 506-516.
Crossref
Lan Zhang, Xupeng Tong, Jingjing Li, Yue Huang, Xinyue Hu, Yi Chen, Jian Huang, Jinhui Wang & Bo Liu. (2015) Apoptotic and autophagic pathways with relevant small-molecule compounds, in cancer stem cells. Cell Proliferation 48:4, pages 385-397.
Crossref
Ling Qi, Kuang Ren, Fang Fang, Dong-Hai Zhao, Ning-Jiang Yang & Yan Li. (2015) Over Expression of BCL2 and Low Expression of Caspase 8 Related to TRAIL Resistance in Brain Cancer Stem Cells. Asian Pacific Journal of Cancer Prevention 16:12, pages 4849-4852.
Crossref
Varun V. Prabhu, Joshua E. Allen, David T. Dicker & Wafik S. El-Deiry. (2015) Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem–like Cells in an Akt/Foxo3a/TRAIL–Dependent Manner. Cancer Research 75:7, pages 1423-1432.
Crossref
George A. Alexiou, Konstantinos I. Tsamis & Athanasios P. Kyritsis. (2015) Targeting Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL): A Promising Therapeutic Strategy in Gliomas. Seminars in Pediatric Neurology 22:1, pages 35-39.
Crossref
Rong Hu, Ying Yang, Zhuogang Liu, Huinan Jiang, Ke Zhu, Jia Li & Wenhui Xu. (2014) The XIAP inhibitor Embelin enhances TRAIL-induced apoptosis in human leukemia cells by DR4 and DR5 upregulation. Tumor Biology 36:2, pages 769-777.
Crossref
Shaoqing Shi, Qiong Wang, Jennings Xu, Jun-Ho Jang, Mabel T. Padilla, Toru Nyunoya, Chengguo Xing, Lin Zhang & Yong Lin. (2015) Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIPL degradation, Ripoptosome formation and autophagy-mediated apoptosis. Oncotarget 6:3, pages 1640-1651.
Crossref
Julianne D. Twomey, William Hallett & Baolin Zhang. 2015. Resistance of Cancer Cells to CTL-Mediated Immunotherapy. Resistance of Cancer Cells to CTL-Mediated Immunotherapy 209 233 .
Iva Jelínková, Barbora Šafaříková, Olga Vondálová Blanářová, Belma Skender, Jiřina Hofmanová, Petr Sova, Mary Pat Moyer, Alois Kozubík, Zdeněk Kolář, Jiří Ehrmann & Alena Hyršlová Vaculová. (2014) Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway. Biochemical Pharmacology 92:3, pages 415-424.
Crossref
Jian Teng, Seyedali Hejazi, Christian E. Badr & Bakhos A. Tannous. (2014) Systemic Anticancer Neural Stem Cells in Combination with a Cardiac Glycoside for Glioblastoma Therapy. Stem Cells 32:8, pages 2021-2032.
Crossref
Ying-Chun He, Fang-Liang Zhou, Yi Shen, Duan-Fang Liao & Deliang Cao. (2014) Apoptotic Death of Cancer Stem Cells for Cancer Therapy. International Journal of Molecular Sciences 15:5, pages 8335-8351.
Crossref
SABRINA LABSCH, LI LIU, NATHALIE BAUER, YIYAO ZHANG, EWA ALEKSANDROWICZ, JURY GLADKICH, FRANK SCHÖNSIEGEL & INGRID HERR. (2014) Sulforaphane and TRAIL induce a synergistic elimination of advanced prostate cancer stem-like cells. International Journal of Oncology 44:5, pages 1470-1480.
Crossref
Alessia Calzolari, Ernestina Saulle, Maria Laura De Angelis, Luca Pasquini, Alessandra Boe, Federica Pelacchi, Lucia Ricci-Vitiani, Marta Baiocchi & Ugo Testa. (2014) Salinomycin Potentiates the Cytotoxic Effects of TRAIL on Glioblastoma Cell Lines. PLoS ONE 9:4, pages e94438.
Crossref
Á. C. Murphy, B. Weyhenmeyer, J. Noonan, S. M. Kilbride, S. Schimansky, K. P. Loh, D. Kögel, A. G. Letai, J. H. M. Prehn & B. M. Murphy. (2013) Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis. Apoptosis 19:4, pages 629-642.
Crossref
Valery R. Polyakov, Neil D. Moorcroft & Amar Drawid. (2014) Enrichment Analysis for Discovering Biological Associations in Phenotypic Screens. Journal of Chemical Information and Modeling 54:2, pages 377-386.
Crossref
Seong Muk Kim, Ji Sun Woo, Chang Hyun Jeong, Chung Heon Ryu, Jae-Deog Jang & Sin-Soo Jeun. (2014) Potential Application of Temozolomide in Mesenchymal Stem Cell-Based TRAIL Gene Therapy Against Malignant Glioma. STEM CELLS Translational Medicine 3:2, pages 172-182.
Crossref
Hiroaki Wakimoto & Khalid Shah. 2013. Stem Cell Therapeutics for Cancer. Stem Cell Therapeutics for Cancer 235 243 .
Thomas G Weber, Thomas Pöschinger, Stefanie Galbán, Alnawaz Rehemtulla & Werner Scheuer. (2013) Noninvasive Monitoring of Pharmacodynamics and Kinetics of a Death Receptor 5 Antibody and Its Enhanced Apoptosis Induction in Sequential Application with Doxorubicin. Neoplasia 15:8, pages 863-874.
Crossref
O Micheau, S Shirley & F Dufour. (2013) Death receptors as targets in cancer. British Journal of Pharmacology 169:8, pages 1723-1744.
Crossref
Sung Kwon. (2013) A formulated red ginseng extract upregulates CHOP and increases TRAIL-mediated cytotoxicity in human hepatocellular carcinoma cells. International Journal of Oncology.
Crossref
Yuan Shi, Gregory Mellier, Sinong Huang, Jacob White, Shazib Pervaiz & Lisa Tucker-Kellogg. (2013) Computational modelling of LY303511 and TRAIL-induced apoptosis suggests dynamic regulation of cFLIP. Bioinformatics 29:3, pages 347-354.
Crossref
Benny Perlstein, Susan A. Finniss, Cathie Miller, Hana Okhrimenko, Gila Kazimirsky, Simona Cazacu, Hae Kyung Lee, Nancy Lemke, Shlomit Brodie, Felix Umansky, Sandra A. Rempel, Mark Rosenblum, Tom Mikklesen, Shlomo Margel & Chaya Brodie. (2013) TRAIL conjugated to nanoparticles exhibits increased anti-tumor activities in glioma cells and glioma stem cells in vitro and in vivo. Neuro-Oncology 15:1, pages 29-40.
Crossref
Casey A Maguire, M Sarah Bovenberg, Matheus HW Crommentuijn, Johanna M Niers, Mariam Kerami, Jian Teng, Miguel Sena-Esteves, Christian E Badr & Bakhos A Tannous. (2013) Triple Bioluminescence Imaging for In Vivo Monitoring of Cellular Processes. Molecular Therapy - Nucleic Acids 2, pages e99.
Crossref
Monica Venere, Jeremy N. Rich & Shideng Bao. 2013. DNA Repair of Cancer Stem Cells. DNA Repair of Cancer Stem Cells 89 103 .
Santiago Gómez-Ruiz, Danijela Maksimović-Ivanić, Sanja Mijatović & Goran N. Kaluđerović. (2012) On the Discovery, Biological Effects, and Use of Cisplatin and Metallocenes in Anticancer Chemotherapy. Bioinorganic Chemistry and Applications 2012, pages 1-14.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.