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Gregory N. Gan & Antonio Jimeno. (2016) Emerging from their burrow: Hedgehog pathway inhibitors for cancer. Expert Opinion on Investigational Drugs 25:10, pages 1153-1166.
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Junjun Jing, Zhuoxuan Wu, Jiahe Wang, Guowen Luo, Hengyi Lin, Yi Fan & Chenchen Zhou. (2023) Hedgehog signaling in tissue homeostasis, cancers, and targeted therapies. Signal Transduction and Targeted Therapy 8:1.
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Saloni Rahi & Sidharth Mehan. (2020) Understanding Abnormal SMO-SHH Signaling in Autism Spectrum Disorder: Potential Drug Target and Therapeutic Goals. Cellular and Molecular Neurobiology 42:4, pages 931-953.
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Ana María Zárate, Christian Espinosa-Bustos, Simón Guerrero, Angélica Fierro, Felipe Oyarzún-Ampuero, Andrew F. G. Quest, Lucia Di Marcotullio, Elena Loricchio, Miriam Caimano, Andrea Calcaterra, Matías González-Quiroz, Adam Aguirre, Jaime Meléndez & Cristian O. Salas. (2021) A New Smoothened Antagonist Bearing the Purine Scaffold Shows Antitumour Activity In Vitro and In Vivo. International Journal of Molecular Sciences 22:16, pages 8372.
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Daniel Doheny, Sherona Sirkisoon, Richard L. Carpenter, Noah Reeve Aguayo, Angelina T. Regua, Marlyn Anguelov, Sara G. Manore, Austin Arrigo, Sara Abu Jalboush, Grace L. Wong, Yang Yu, Calvin J. Wagner, Michael Chan, Jimmy Ruiz, Alexandra Thomas, Roy Strowd, Jiayuh Lin & Hui-Wen Lo. (2020) Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis. Oncogene 39:42, pages 6589-6605.
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Li Tian, Lin Yang, Wenjing Zheng, Yinqing Hu, Peikun Ding, Zheng Wang, Duo Zheng, Li Fu, Bin Chen, Tian Xiao, Yuejun Wang, Feng Chen, Jun Liu, Kaiping Gao, Sipeng Shen & Rihong Zhai. (2020) RNA sequencing of exosomes revealed differentially expressed long noncoding RNAs in early-stage esophageal squamous cell carcinoma and benign esophagitis. Epigenomics 12:6, pages 525-541.
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Jennifer Teichman, Lorin Dodbiba, Henry Thai, Andrew Fleet, Trevor Morey, Lucy Liu, Madison McGregor, Dangxiao Cheng, Zhuo Chen, Gail Darling, Yonathan Brhane, Yuyao Song, Osvaldo Espin-Garcia, Wei Xu, Hala Girgis, Joerg Schwock, Helen MacKay, Robert Bristow, Laurie Ailles & Geoffrey Liu. (2018) Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma. PLOS ONE 13:5, pages e0194809.
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Juliann E. Kosovec, Ali H. Zaidi, Ashten N. Omstead, Daisuke Matsui, Mark J. Biedka, Erin J. Cox, Patrick T. Campbell, Robert W.W. Biederman, Ronan J. Kelly & Blair A. Jobe. (2017) CDK4/6 dual inhibitor abemaciclib demonstrates compelling preclinical activity against esophageal adenocarcinoma: a novel therapeutic option for a deadly disease. Oncotarget 8:59, pages 100421-100432.
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Tomohiro Ohashi, Yuta Tanaka, Zenyu Shiokawa, Hiroshi Banno, Toshio Tanaka, Sachio Shibata, Yoshihiko Satoh, Hiroko Yamakawa, Yukiko Yamamoto, Harumi Hattori, Shigeru Kondo, Maki Miyamoto, Hideaki Tojo, Atsuo Baba & Satoshi Sasaki. (2015) Synthesis and evaluation of hedgehog signaling inhibitor with novel core system. Bioorganic & Medicinal Chemistry 23:15, pages 4777-4791.
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