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Cancer Investigation Volume 15, 1997 - Issue 6
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Original Article

A Pharmacodynamic Study of Morphine and Its Glucuronide Metabolites After Single Morphine Dosing in Cancer Patients with Pain

Mark Hoffman Division of Hematology/Oncology Department of Medicine, Long Island Jewish Medical Center, New Hyde Park, New York
,
Jing-Chu Xu Division of Hematology/Oncology Department of Medicine, Long Island Jewish Medical Center, New Hyde Park, New York
,
Candace Smith St. John's University College of Pharmacy and Pharmacokinetic Service Long Island Jewish Medical Center
,
Chris Fanelli Division of Toxicology Department of Pathology, Long Island Jewish Medical Center
,
Valda Pascal Division of Hematology/Oncology Department of Medicine, Long Island Jewish Medical Center, New Hyde Park, New York
,
Colleen Degaetano Division of Hematology/Oncology Department of Medicine, Long Island Jewish Medical Center, New Hyde Park, New York
,
Gerard Meenan Division of Toxicology Department of Pathology, Long Island Jewish Medical Center
,
Michael Lehrer Division of Toxicology Department of Pathology, Long Island Jewish Medical Center
,
Martin Lesser Statistical Consulting, East RockawayNew York
&
Marc Citron Division of Hematology/Oncology Department of Medicine, Long Island Jewish Medical Center, New Hyde Park, New York
 show all
Pages 542-547 | Published online: 11 Jun 2009

Citations (16)

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Akram M. El-Didamony, Monir Z. Saad & Nora O. Saleem. (2015) Spectrophotometric determination of some analgesic drugs in pharmaceutical formulations using N-bromosuccinimide as an oxidant. Journal of the Association of Arab Universities for Basic and Applied Sciences 17:1, pages 43-50.
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Eva Brandšteterová, Eva Blahová & Jana Netriová. (2002) SIMPLE GENERIC SPE ASSAY FOR HPLC ANALYSIS OF MORPHINE AND ITS GLUCURONIDES IN SERUM SAMPLES. Journal of Liquid Chromatography & Related Technologies 25:16, pages 2521-2534.
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Articles from other publishers (14)

Florian Gabel, Volodya Hovhannisyan, Abdel-Karim Berkati & Yannick Goumon. (2022) Morphine-3-Glucuronide, Physiology and Behavior. Frontiers in Molecular Neuroscience 15.
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Philip J Wiffen, Bee Wee & R Andrew Moore. (2016) Oral morphine for cancer pain. Cochrane Database of Systematic Reviews 2021:3.
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Risako Kon, Nobutomo Ikarashi, Akio Hayakawa, Yusuke Haga, Aika Fueki, Yoshiki Kusunoki, Masataka Tajima, Wataru Ochiai, Yoshiaki Machida & Kiyoshi Sugiyama. (2015) Morphine-Induced Constipation Develops With Increased Aquaporin-3 Expression in the Colon via Increased Serotonin Secretion. Toxicological Sciences 145:2, pages 337-347.
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R. Klimas & G. Mikus. (2014) Morphine-6-glucuronide is responsible for the analgesic effect after morphine administration: a quantitative review of morphine, morphine-6-glucuronide, and morphine-3-glucuronide. British Journal of Anaesthesia 113:6, pages 935-944.
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Shujun Xia, Dong Choe, Lenin Hernandez & Adrienne Birnbaum. (2014) Does Initial Hydromorphone Relieve Pain Best if Dosing Is Fixed or Weight Based?. Annals of Emergency Medicine 63:6, pages 692-698.e4.
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Akram M. El‐Didamony & Ismail I. Ali. (2013) Spectrofluorimetric and Spectrophotometric Analysis of Two Analgesic Drugs in Pharmaceutical Formulations and Biological Fluids. Journal of Forensic Sciences 58:5, pages 1322-1329.
Crossref
Philip J Wiffen, Bee Wee & R Andrew Moore. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Steven Karch. 2008. Karch's Pathology of Drug Abuse, Fourth Edition. Karch's Pathology of Drug Abuse, Fourth Edition 367 374 .
Philip J Wiffen & Henry J McQuay. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
David Casarett. (2005) Ethical Considerations in End-of-Life Care and Research. Journal of Palliative Medicine 8:supplement 1, pages s-148-s-160.
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PJ Wiffen, JE Edwards, J Barden & HJM McQuay. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
David J Casarett. (2003) Assessing Decision-Making Capacity in the Setting of Palliative Care Research. Journal of Pain and Symptom Management 25:4, pages S6-S13.
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Gertrud Andersen, Lona Christrup & Per Sjøgren. (2003) Relationships Among Morphine Metabolism, Pain and Side Effects During Long-Term Treatment. Journal of Pain and Symptom Management 25:1, pages 74-91.
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David J. Casarett & Jason Karlawish. (2001) Beyond Informed Consent: The Ethical Design of Pain Research. Pain Medicine 2:2, pages 138-146.
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