Advanced search
Publication Cover
Critical Reviews in Biotechnology Volume 34, 2014 - Issue 2
Submit an article Journal homepage
1,324
Views
72
CrossRef citations to date
0
Altmetric
Review Article

Biopolymer nanoparticle production for controlled release of biopharmaceuticals

David HudsonDepartment of Chemical and Biochemical Engineering, The University of Western Ontario London, ONCanada
&
Argyrios MargaritisDepartment of Chemical and Biochemical Engineering, The University of Western Ontario London, ONCanadaCorrespondence[email protected]
Pages 161-179 | Received 20 Jul 2012, Accepted 22 Oct 2012, Published online: 07 Jan 2013

Citations (72)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Yuan Gao, Rui Wang, Lixia Zhao & Anchang Liu. (2021) Natural polymeric nanocarriers in malignant glioma drug delivery and targeting. Journal of Drug Targeting 29:9, pages 960-973.
Read now
Marlene Lopes, Barbara Abrahim, Francisco Veiga, Raquel Seiça, Lucio Mendes Cabral, Philippe Arnaud, José Carlos Andrade & Antonio J. Ribeiro. (2017) Preparation methods and applications behind alginate-based particles. Expert Opinion on Drug Delivery 14:6, pages 769-782.
Read now

Articles from other publishers (70)

Li Song, Yi Chen, Zitian Liu, Linxian Zhu, Lushan Song, Mingran Zhang, Tianrui Xue, Binfen Lv, Huiping Liu & Xiaowei Zhang. (2023) Preparation, characterization, and stability assessment of a nano-delivery system loaded with phosvitin phosphopeptide-calcium chelate. Food Bioscience 56, pages 103306.
Crossref
Rani Bushra, Mehraj Ahmad, Farzad Seidi, Quratulen, Junlong Song, Yongcan Jin & Huining Xiao. (2023) Polysaccharide-based nanoassemblies: From synthesis methodologies and industrial applications to future prospects. Advances in Colloid and Interface Science, pages 102953.
Crossref
Bharat Kumar Reddy Sanapalli, Vidyasrilekha Yele, Mantosh Kumar Singh, Shilpa.N. Thumbooru, Madhukiran Parvathaneni & Veera Venkata Satyanarayana Reddy Karri. (2023) Human beta defensin-2 loaded PLGA nanoparticles impregnated in collagen-chitosan composite scaffold for the management of diabetic wounds. Biomedicine & Pharmacotherapy 161, pages 114540.
Crossref
Abraham Abbey Paul, Victor Markus, Kathelina Kristollari & Robert S. Marks. 2023. Alginate - Applications and Future Perspectives [Working Title]. Alginate - Applications and Future Perspectives [Working Title].
Amel Balla, Allaoua Silini, Hafsa Cherif-Silini, Ali Chenari Bouket, Faizah N. Alenezi & Lassaad Belbahri. (2022) Recent Advances in Encapsulation Techniques of Plant Growth-Promoting Microorganisms and Their Prospects in the Sustainable Agriculture. Applied Sciences 12:18, pages 9020.
Crossref
Keyhan Mohammadi, Mahmood Alizadeh Sani, Maryam Azizi-Lalabadi & David Julian McClements. (2022) Recent progress in the application of plant-based colloidal drug delivery systems in the pharmaceutical sciences. Advances in Colloid and Interface Science 307, pages 102734.
Crossref
Saumya Dash, Adeeba Shakeel & Sujata Mohanty. (2022) Impact of Nanotechnology on the Realm of Stem Cells and Regenerative Medicine. ChemNanoMat 8:9.
Crossref
Zhijing Yang, Weiwei Liu, Huimin Liu, Rong Li, Lu Chang, Shaoning Kan, Ming Hao & Dongxu Wang. (2022) The applications of polysaccharides in dentistry. Frontiers in Bioengineering and Biotechnology 10.
Crossref
Rajarshi Roychoudhury. 2022. Bionanotechnology: Next-Generation Therapeutic Tools. Bionanotechnology: Next-Generation Therapeutic Tools 84 97 .
Nicola Judge, Dražen Pavlović, Evelin Moldenhauer, Paul Clarke, Ruairi Brannigan & Andreas Heise. (2022) Influence of the block copolypeptide surfactant structure on the size of polypeptide nanoparticles obtained by mini emulsion polymerisation. Polymer Chemistry 13:19, pages 2822-2830.
Crossref
Umair Baig, M. Faizan & Abdul Waheed. (2022) A review on super-wettable porous membranes and materials based on bio-polymeric chitosan for oil-water separation. Advances in Colloid and Interface Science 303, pages 102635.
Crossref
Prachi Pandey, Jayvadan Patel & Samarth Kumar. 2022. Sustainable Nanotechnology. Sustainable Nanotechnology 89 116 .
Surya Prakash, Manish, Priya Bansal, Abhishek Kumar, Vidhu Saxena, Vinay Kumar & Deepti Katiyar. (2022) Overview and in-silico pharmacological profiling of Gliadin: A potential biomaterial. Materials Today: Proceedings 62, pages 276-282.
Crossref
Maanas Sharma, Kshirod K. Dash & Laxmikant S. Badwaik. (2022) Physicochemical and release behaviour of phytochemical compounds based on black jamun pulp extracts-filled alginate hydrogel beads through vibration dripping extrusion. International Journal of Biological Macromolecules 194, pages 715-725.
Crossref
Xiao Chen, Tong-Yu Zhang, Yan-Chao Wu, Pi-Xian Gong & Hui-Jing Li. (2022) Foxtail millet prolamin as an effective encapsulant deliver curcumin by fabricating caseinate stabilized composite nanoparticles. Food Chemistry 367, pages 130764.
Crossref
Adeeba Shakeel, Saumya Dash, Vishnu Krishna Kumar & Sujata Mohanty. 2022. Biomimetic Biomaterials for Tissue Regeneration and Drug Delivery. Biomimetic Biomaterials for Tissue Regeneration and Drug Delivery 75 98 .
Mariana Carolina Di Santo, Cecilia Luciana D’ Antoni, Ana Paula Domínguez Rubio, Agustina Alaimo & Oscar Edgardo Pérez. (2021) Chitosan-tripolyphosphate nanoparticles designed to encapsulate polyphenolic compounds for biomedical and pharmaceutical applications − A review. Biomedicine & Pharmacotherapy 142, pages 111970.
Crossref
Ozge Esim, Mustafa Emre Gedik, Ayse Lale Dogan, Gurcan Gunaydin & Canan Hascicek. (2021) Development of carboplatin loaded bovine serum albumin nanoparticles and evaluation of its effect on an ovarian cancer cell line. Journal of Drug Delivery Science and Technology 64, pages 102655.
Crossref
Yale Luck Nunes, Fernando Lima de Menezes, Isamayra Germano de Sousa, Antônio Luthierre Gama Cavalcante, Francisco Thálysson Tavares Cavalcante, Katerine da Silva Moreira, André Luiz Barros de Oliveira, Gabrielly Ferreira Mota, José Erick da Silva Souza, Italo Rafael de Aguiar Falcão, Thales Guimaraes Rocha, Roberta Bussons Rodrigues Valério, Pierre Basílio Almeida Fechine, Maria Cristiane Martins de Souza & José C.S. dos Santos. (2021) Chemical and physical Chitosan modification for designing enzymatic industrial biocatalysts: How to choose the best strategy?. International Journal of Biological Macromolecules 181, pages 1124-1170.
Crossref
Slaven Jurić, Marina Jurić, Anet Režek Jambrak & Marko Vinceković. (2021) Tailoring Alginate/Chitosan Microparticles Loaded with Chemical and Biological Agents for Agricultural Application and Production of Value-Added Foods. Applied Sciences 11:9, pages 4061.
Crossref
Imran Moin, Largee Biswas, Md Zafaryab, Namrata Kumari, Ankita Leekha, Disha Mittal & Anita Kamra Verma. (2021) In vitro Toxico-genomics of Etoposide Loaded Gelatin Nanoparticles and Its in-vivo Therapeutic Potential: Pharmacokinetics, Biodistribution and Tumor Regression in Ehrlich Ascites Carcinoma (EAC) Mice Model. Frontiers in Nanotechnology 3.
Crossref
Ozge Esim & Canan Hascicek. (2021) Albumin-based Nanoparticles as Promising Drug Delivery Systems for Cancer Treatment. Current Pharmaceutical Analysis 17:3, pages 346-359.
Crossref
Erika Fleming & Yangchao Luo. (2021) Co-delivery of synergistic antioxidants from food sources for the prevention of oxidative stress. Journal of Agriculture and Food Research 3, pages 100107.
Crossref
Belen Reig-Vano, Bartosz Tylkowski, Xavier Montané & Marta Giamberini. (2021) Alginate-based hydrogels for cancer therapy and research. International Journal of Biological Macromolecules 170, pages 424-436.
Crossref
Silvia Voci, Massimo Fresta & Donato Cosco. (2021) Gliadins as versatile biomaterials for drug delivery applications. Journal of Controlled Release 329, pages 385-400.
Crossref
Marko Vinceković, Slaven Jurić, Marijan Marijan, Marko Viskić, Kristina Vlahoviček-Kahlina & Luna Maslov Bandić. 2021. Aromatic Herbs in Food. Aromatic Herbs in Food 263 322 .
Sajad Ahmad Mir, Amir Gull, Gazalla Akhtar, Sajad Ahmad Rather, Farooq Ahmad Masoodi, Tariq Ahmad Ganaie & Sajad Mohd Wani. 2021. Advanced Green Materials. Advanced Green Materials 85 108 .
V. Ponnusami. 2021. Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery. Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery 105 120 .
Prakashkumar Nallasamy & Suganthy Natarajan. 2021. Bioprospecting Algae for Nanosized Materials. Bioprospecting Algae for Nanosized Materials 3 22 .
Shalja Verma & Anand Kumar Pandey. 2021. Sustainable Agriculture Reviews 55. Sustainable Agriculture Reviews 55 135 170 .
Mohammad Doroudian, Andrew O'Neill, Ciaran O'Reilly, Aisling Tynan, Leona Mawhinney, Aoife McElroy, Shanice S. Webster, Ronan MacLoughlin, Yuri Volkov, Michelle E Armstrong, George A. O'Toole, Adriele Prina-Mello & Seamas C Donnelly. (2020) Aerosolized drug-loaded nanoparticles targeting migration inhibitory factors inhibit Pseudomonas aeruginosa -induced inflammation and biofilm formation . Nanomedicine 15:30, pages 2933-2953.
Crossref
Kaili Wang, Mingqi Liu & Ran Mo. (2020) Polysaccharide-Based Biomaterials for Protein Delivery. Medicine in Drug Discovery 7, pages 100031.
Crossref
Chengsheng Jia, Dandan Cao, Suping Ji, Xiaoming Zhang & Bertrand Muhoza. (2020) Tannic acid-assisted cross-linked nanoparticles as a delivery system of eugenol: The characterization, thermal degradation and antioxidant properties. Food Hydrocolloids 104, pages 105717.
Crossref
Jiawei Chen & Liandong Hu. (2019) Nanoscale Delivery System for Nutraceuticals: Preparation, Application, Characterization, Safety, and Future Trends. Food Engineering Reviews 12:1, pages 14-31.
Crossref
Preetam Bala & Sangeeta N. Kale. 2020. Advances in Bioengineering. Advances in Bioengineering 183 197 .
Shoubao Wang, Yao Xiong, Jingting Chen, Abdulsamad Ghanem, Yinmin Wang, Jun Yang & Binbin Sun. (2019) Three Dimensional Printing Bilayer Membrane Scaffold Promotes Wound Healing. Frontiers in Bioengineering and Biotechnology 7.
Crossref
Nirmala Kumari Jangid, Deepa Hada & Kavita Rathore. (2019) Chitosan as an emerging object for biological and biomedical applications. Journal of Polymer Engineering 39:8, pages 689-703.
Crossref
Milad Fathi-Achachelouei, Helena Knopf-Marques, Cristiane Evelise Ribeiro da Silva, Julien Barthès, Erhan Bat, Aysen Tezcaner & Nihal Engin Vrana. (2019) Use of Nanoparticles in Tissue Engineering and Regenerative Medicine. Frontiers in Bioengineering and Biotechnology 7.
Crossref
Paulina Paul, Beata Kolesinska & Witold Sujka. (2019) Chitosan and Its Derivatives - Biomaterials with Diverse Biological Activity for Manifold Applications. Mini-Reviews in Medicinal Chemistry 19:9, pages 737-750.
Crossref
Faiza Shahid, Afsheen Aman & Shah Ali Ul Qader. (2019) Immobilization of Dextranase Using Anionic Natural Polymer Alginate as a Matrix for the Degradation of a Long-Chain Biopolymer (Dextran). International Journal of Polymer Science 2019, pages 1-8.
Crossref
Shabnam Mohebbi, Mojtaba Nasiri Nezhad, Payam Zarrintaj, Seyed Hassan Jafari, Saman Seyed Gholizadeh, Mohammad Reza Saeb & Masoud Mozafari. (2019) Chitosan in Biomedical Engineering: A Critical Review. Current Stem Cell Research & Therapy 14:2, pages 93-116.
Crossref
Simone A. Costa, Davoud Mozhdehi, Michael J. Dzuricky, Farren J. Isaacs, Eric M. Brustad & Ashutosh Chilkoti. (2018) Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug. Nano Letters 19:1, pages 247-254.
Crossref
Xiao-Heng Zhao, Franklin R. Tay, Yan-Jun Fang, Liu-Yan Meng & Zhuan Bian. (2019) Topical application of phenytoin or nifedipine-loaded PLGA microspheres promotes periodontal regeneration in vivo. Archives of Oral Biology 97, pages 42-51.
Crossref
Shufang Yang, Lei Dai, Cuixia Sun & Yanxiang Gao. (2018) Characterization of curcumin loaded gliadin-lecithin composite nanoparticles fabricated by antisolvent precipitation in different blending sequences. Food Hydrocolloids 85, pages 185-194.
Crossref
André T. StevensonJr.Jr., Spencer A. Lewis & Abby R. Whittington. (2018) Filtration initiated selective homogeneity (FISH) desolvation: A new method to prepare gelatin nanoparticles with high physicochemical consistency. Food Hydrocolloids 84, pages 337-342.
Crossref
Johan Karlsson, Hannah J. VaughanJordan J. Green. (2018) Biodegradable Polymeric Nanoparticles for Therapeutic Cancer Treatments. Annual Review of Chemical and Biomolecular Engineering 9:1, pages 105-127.
Crossref
Natassa Pippa, Theodore Sentoukas, Stergios Pispas, Costas Demetzos, Apostolos Papalois & Nikolaos Bouropoulos. (2018) pH-responsive polymeric nanoassemblies encapsulated into alginate beads: morphological characterization and swelling studies. Journal of Polymer Research 25:5.
Crossref
Rongli Zhang, Jingjing Lv, Cuige Zhang, Renchun Yang, Xingchen Sun, Bo Song & Ching-Ping Wong. (2018) Alginate-based colloid particles from direct chemical self-assembly using as particulate emulsifiers. Colloids and Surfaces A: Physicochemical and Engineering Aspects 542, pages 15-20.
Crossref
Yasuyuki Maki, Wataru Saito & Toshiaki Dobashi. (2018) Preparation and thermoresponsive behaviors of UV-crosslinked gelatin nanogels. Journal of Biorheology 32:1, pages 15-19.
Crossref
Jie Yang, Hao Lu, Man Li, Jing Liu, Shuangling Zhang, Liu Xiong & Qingjie Sun. (2017) Development of chitosan-sodium phytate nanoparticles as a potent antibacterial agent. Carbohydrate Polymers 178, pages 311-321.
Crossref
Katherina Fernández, Marlene Roeckel, Edgardo Canales & Javiera Dumont. (2017) Modeling of the Nanoparticles Absorption Under a Gastrointestinal Simulated Ambient Condition. AAPS PharmSciTech 18:7, pages 2691-2701.
Crossref
. 2017. Carrier‒Mediated Dermal Delivery. Carrier‒Mediated Dermal Delivery 265 280 .
Gisele Façanha Diógenes Teixeira, Antonio Eufrásio Vieira-Neto, Flávio Nogueira da Costa, Angelo Roncalli Alves e Silva & Adriana Rolim Campos. (2017) Antinociceptive effect of (-)-α-bisabolol in nanocapsules. Biomedicine & Pharmacotherapy 91, pages 946-950.
Crossref
Kegang Liu, Xueya Wang, Vasilis Ntziachristos, Stephan Marsch & Patrick Hunziker. (2017) Polymeric nanosystems for near-infrared multispectral photoacoustic imaging: Synthesis, characterization and in vivo evaluation. European Polymer Journal 88, pages 713-723.
Crossref
Carina Peres, Ana I. Matos, João Conniot, Vanessa Sainz, Eva Zupančič, Joana M. Silva, Luís Graça, Rogério Sá Gaspar, Véronique Préat & Helena F. Florindo. (2017) Poly(lactic acid)-based particulate systems are promising tools for immune modulation. Acta Biomaterialia 48, pages 41-57.
Crossref
Lucia Zakharova, Tatiana Pashirova, Ruslan Kashapov, Dinar Gabdrakhmanov & Oleg Sinyashin. 2017. Nanostructures for Drug Delivery. Nanostructures for Drug Delivery 749 806 .
Nikolas T. Weissmueller, Hoang D. Lu, Amanda Hurley & Robert K. Prud’homme. (2016) Nanocarriers from GRAS Zein Proteins to Encapsulate Hydrophobic Actives. Biomacromolecules 17:11, pages 3828-3837.
Crossref
Diana Gaspar, Carina Peres, Helena Florindo & António Almeida. 2016. Handbook of Polyester Drug Delivery Systems. Handbook of Polyester Drug Delivery Systems 521 561 .
Kiran Kumar Chereddy, Gaëlle Vandermeulen & Véronique Préat. (2016) PLGA based drug delivery systems: Promising carriers for wound healing activity. Wound Repair and Regeneration 24:2, pages 223-236.
Crossref
Patrícia Severino, Classius F. da Silva, Mariana A. da Silva, Maria H. A. Santana & Eliana B. Souto. (2014) Chitosan Cross-Linked Pentasodium Tripolyphosphate Micro/Nanoparticles Produced by Ionotropic Gelation. Sugar Tech 18:1, pages 49-54.
Crossref
Jayachandran Venkatesan, Sukumaran Anil, Se-Kwon Kim & Min Shim. (2016) Seaweed Polysaccharide-Based Nanoparticles: Preparation and Applications for Drug Delivery. Polymers 8:2, pages 30.
Crossref
Claudia Conte, Sara Maiolino, Diogo Silva Pellosi, Agnese Miro, Francesca Ungaro & Fabiana Quaglia. 2016. Light-Responsive Nanostructured Systems for Applications in Nanomedicine. Light-Responsive Nanostructured Systems for Applications in Nanomedicine 61 112 .
Amir Hossein Saberi & David Julian McClements. (2015) Fabrication of protein nanoparticles and microparticles within water domains formed in surfactant–oil–water mixtures: Phase inversion temperature method. Food Hydrocolloids 51, pages 441-448.
Crossref
Randy Cheung, Tzi Ng, Jack Wong & Wai Chan. (2015) Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications. Marine Drugs 13:8, pages 5156-5186.
Crossref
Sara Pistone, Dafina Qoragllu, Gro Smistad & Marianne Hiorth. (2015) Formulation and preparation of stable cross-linked alginate–zinc nanoparticles in the presence of a monovalent salt. Soft Matter 11:28, pages 5765-5774.
Crossref
Christoph Hoennscheidt, Argyrios Margaritis & Rainer Krull. (2015) Novel applications of ubiquinone biopolymer nanocarriers for preventive and regenerative therapeutics: The Saccharomyces cerevisiae paradigm. International Journal of Pharmaceutics 478:1, pages 416-425.
Crossref
Jin Huk Choi & Maria A. Croyle. (2013) Emerging Targets and Novel Approaches to Ebola Virus Prophylaxis and Treatment. BioDrugs 27:6, pages 565-583.
Crossref
Christoph Hoennscheidt, Dirk Kreyenschulte, Argyrios Margaritis & Rainer Krull. (2013) Production of stable quinine nanodispersions using esterified γ-polyglutamic acid biopolymer. Biochemical Engineering Journal 79, pages 259-266.
Crossref
Frank Hellmers, Peter Ferguson, James Koropatnick, Rainer Krull & Argyrios Margaritis. (2013) Characterization and in vitro cytotoxicity of doxorubicin-loaded γ-polyglutamic acid-chitosan composite nanoparticles. Biochemical Engineering Journal 75, pages 72-78.
Crossref
Xiaoqin Wang & Xuewu Zhang. (2013) Separation, antitumor activities, and encapsulation of polypeptide from Chlorella pyrenoidosa . Biotechnology Progress 29:3, pages 681-687.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.