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Critical Reviews in Biotechnology Volume 34, 2014 - Issue 3
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Review Article

Fungal arachidonic acid-rich oil: research, development and industrialization

Xiao-Jun JiState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology NanjingPeople’s Republic of China
,
Lu-Jing RenState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology NanjingPeople’s Republic of China
,
Zhi-Kui NieState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology NanjingPeople’s Republic of China
,
He HuangState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology NanjingPeople’s Republic of ChinaCorrespondence[email protected]
&
Ping-Kai OuyangState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology NanjingPeople’s Republic of China
Pages 197-214 | Received 31 Jul 2012, Accepted 08 Jan 2013, Published online: 30 Apr 2013

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Loutfy H. MadkourLoutfy H. Madkour. 2020. Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses. Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses 193 260 .
Huidan Zhang, Zhuojun Wang, Yingang Feng, Qiu Cui & Xiaojin Song. (2019) Phytohormones as stimulators to improve arachidonic acid biosynthesis in Mortierella alpina. Enzyme and Microbial Technology 131, pages 109381.
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Wei-Jian Wang, He Huang & Xiao-Jun Ji. 2019. Systems and Synthetic Biotechnology for Production of Nutraceuticals. Systems and Synthetic Biotechnology for Production of Nutraceuticals 189 202 .
Zhi-Yan Du, Jonathan Alvaro, Brennan Hyden, Krzysztof Zienkiewicz, Nils Benning, Agnieszka Zienkiewicz, Gregory Bonito & Christoph Benning. (2018) Enhancing oil production and harvest by combining the marine alga Nannochloropsis oceanica and the oleaginous fungus Mortierella elongata. Biotechnology for Biofuels 11:1.
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Huidan Zhang, Dong Lu, Xin Li, Yingang Feng, Qiu Cui & Xiaojin Song. (2018) Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in Mortierella alpina. BMC Biotechnology 18:1.
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Rodrigo Ledesma-Amaro, Alberto Jiménez & José Luis Revuelta. (2018) Pathway Grafting for Polyunsaturated Fatty Acids Production in Ashbya gossypii through Golden Gate Rapid Assembly . ACS Synthetic Biology 7:10, pages 2340-2347.
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Xin Tang, Haiqin Chen, Tiantian Mei, Chengfeng Ge, Zhennan Gu, Hao Zhang, Yong Q. Chen & Wei Chen. (2018) Characterization of an Omega-3 Desaturase From Phytophthora parasitica and Application for Eicosapentaenoic Acid Production in Mortierella alpina. Frontiers in Microbiology 9.
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Kun Shi, Zhen Gao, Lu Lin, Wei-Jian Wang, Xin-Qiao Shi, Xiao Yu, Ping Song, Lu-Jing Ren, He Huang & Xiao-Jun Ji. (2018) Manipulating the generation of reactive oxygen species through intermittent hypoxic stress for enhanced accumulation of arachidonic acid-rich lipids. Chemical Engineering Science 186, pages 36-43.
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Yadong Yu, Lei Zhang, Tao Li, Na Wu, Ling Jiang, Xiaojun Ji & He Huang. (2018) How nitrogen sources influence Mortierella alpina aging: From the lipid droplet proteome to the whole-cell proteome and metabolome. Journal of Proteomics 179, pages 140-149.
Crossref
Hatem Tallima & Rashika El Ridi. (2018) Arachidonic acid: Physiological roles and potential health benefits – A review. Journal of Advanced Research 11, pages 33-41.
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Si‐Yu Zeng, Hu‐Hu Liu, Tian‐Qiong Shi, Ping Song, Lu‐Jing Ren, He Huang & Xiao‐Jun Ji. (2018) Recent Advances in Metabolic Engineering of Yarrowia lipolytica for Lipid Overproduction . European Journal of Lipid Science and Technology 120:3, pages 1700352.
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Xiangyu Li, Chao Yu, Jianming Yao, Zhiming Wang & Shuhuan Lu. (2018) An Online Respiratory Quotient-Feedback Strategy of Feeding Yeast Extract for Efficient Arachidonic Acid Production by Mortierella alpina. Frontiers in Bioengineering and Biotechnology 5.
Crossref
Sameh A. Korma, Xiaoqiang Zou, Abdelmoneim H. Ali, Sherif M. Abed, Qingzhe Jin & Xingguo Wang. (2018) Preparation of structured lipids enriched with medium- and long-chain triacylglycerols by enzymatic interesterification for infant formula. Food and Bioproducts Processing 107, pages 121-130.
Crossref
Wen-Jia Wu, Ai-Hui Zhang, Chao Peng, Lu-Jing Ren, Ping Song, Ya-Dong Yu, He Huang & Xiao-Jun Ji. (2017) An efficient multi-stage fermentation strategy for the production of microbial oil rich in arachidonic acid in Mortierella alpina. Bioresources and Bioprocessing 4:1.
Crossref
Hu-Hu Liu, Si-Yu Zeng, Tian-Qiong Shi, Ying Ding, Lu-Jing Ren, Ping Song, He Huang, Catherine Madzak & Xiao-Jun Ji. (2017) A Yarrowia lipolytica strain engineered for arachidonic acid production counteracts metabolic burden by redirecting carbon flux towards intracellular fatty acid accumulation at the expense of organic acids secretion. Biochemical Engineering Journal 128, pages 201-209.
Crossref
Tian-Qiong Shi, Guan-Nan Liu, Rong-Yu Ji, Kun Shi, Ping Song, Lu-Jing Ren, He Huang & Xiao-Jun Ji. (2017) CRISPR/Cas9-based genome editing of the filamentous fungi: the state of the art. Applied Microbiology and Biotechnology 101:20, pages 7435-7443.
Crossref
Sherif M. Abed, Xiaoqiang Zou, Abdelmoneim H. Ali, Qingzhe Jin & Xingguo Wang. (2017) Profiling of triacylglycerol composition in arachidonic acid single cell oil from Mortierella alpina by using ultra-performance liquid chromatography-electrospray ionization-quadrupole-time-of-flight mass spectrometry. Journal of Food Composition and Analysis 62, pages 245-253.
Crossref
Xin Zhang, Ling Jiang, Li-Ying Zhu, Qin-Ke Shen, Xiao-Jun Ji, He Huang & Hong-Man Zhang. (2017) Effects of aeration on metabolic profiles of Mortierella alpina during the production of arachidonic acid . Journal of Industrial Microbiology and Biotechnology 44:8, pages 1225-1235.
Crossref
Kun Shi, Zhen Gao, Tian-Qiong Shi, Ping Song, Lu-Jing Ren, He Huang & Xiao-Jun Ji. (2017) Reactive Oxygen Species-Mediated Cellular Stress Response and Lipid Accumulation in Oleaginous Microorganisms: The State of the Art and Future Perspectives. Frontiers in Microbiology 8.
Crossref
Yadong Yu, Tao Li, Na Wu, Ling Jiang, Xiaojun Ji & He Huang. (2017) The Role of Lipid Droplets in Mortierella alpina Aging Revealed by Integrative Subcellular and Whole-Cell Proteome Analysis. Scientific Reports 7:1.
Crossref
Jin V. Lee, Ran Furman & Paul H. Axelsen. (2017) Biosynthesis of uniformly labeled 13C- and 14C-arachidonic acid in Mortierella alpina. Bioresource Technology 227, pages 142-146.
Crossref
Hu-Hu Liu, Catherine Madzak, Mei-Li Sun, Lu-Jing Ren, Ping Song, He Huang & Xiao-Jun Ji. (2017) Engineering Yarrowia lipolytica for arachidonic acid production through rapid assembly of metabolic pathway. Biochemical Engineering Journal 119, pages 52-58.
Crossref
Igor G. Morgunov, Svetlana V. Kamzolova, Emilia G. Dedyukhina, Tatiana I. Chistyakova, Julia N. Lunina, Alexey A. Mironov, Nadezda N. Stepanova, Olga N. Shemshura & Mikhail B. Vainshtein. (2016) Application of organic acids for plant protection against phytopathogens. Applied Microbiology and Biotechnology 101:3, pages 921-932.
Crossref
Klaus-Peter Stahmann. 2017. Reference Module in Life Sciences. Reference Module in Life Sciences.
Yadong Yu, Tao Li, Na Wu, Lujing Ren, Ling Jiang, Xiaojun Ji & He Huang. (2016) Mechanism of Arachidonic Acid Accumulation during Aging in Mortierella alpina : A Large-Scale Label-Free Comparative Proteomics Study . Journal of Agricultural and Food Chemistry 64:47, pages 9124-9134.
Crossref
Dong-Sheng Guo, Xiao-Jun Ji, Lu-Jing Ren, Gan-Lu Li, Feng-Wei Yin & He Huang. (2016) Development of a real-time bioprocess monitoring method for docosahexaenoic acid production by Schizochytrium sp.. Bioresource Technology 216, pages 422-427.
Crossref
Guangfei Hao, Haiqin Chen, Zhennan Gu, Hao Zhang, Wei Chen & Yong Q. Chen. (2016) Metabolic Engineering of Mortierella alpina for Enhanced Arachidonic Acid Production through the NADPH-Supplying Strategy. Applied and Environmental Microbiology 82:11, pages 3280-3288.
Crossref
Hu-Hu Liu, Xiao-Jun Ji & He Huang. (2015) Biotechnological applications of Yarrowia lipolytica: Past, present and future. Biotechnology Advances 33:8, pages 1522-1546.
Crossref
Ai-Hui Zhang, Xiao-Jun Ji, Wen-Jia Wu, Lu-Jing Ren, Ya-Dong Yu & He Huang. (2015) Lipid Fraction and Intracellular Metabolite Analysis Reveal the Mechanism of Arachidonic Acid-Rich Oil Accumulation in the Aging Process of Mortierella alpina . Journal of Agricultural and Food Chemistry 63:44, pages 9812-9819.
Crossref
Xiao-Jun Ji, Kai-Qiang Mo, Lu-Jing Ren, Gan-Lu Li, Jian-Zhong Huang & He Huang. (2015) Genome Sequence of Schizochytrium sp. CCTCC M209059, an Effective Producer of Docosahexaenoic Acid-Rich Lipids . Genome Announcements 3:4.
Crossref
Wenjia Wu, Jiacheng Yan, Xiaojun Ji, Xin Zhang, Jingsheng Shang, Lina Sun, Lujing Ren & He Huang. (2015) Lipid characterization of an arachidonic acid-rich oil producing fungus Mortierella alpina. Chinese Journal of Chemical Engineering 23:7, pages 1183-1187.
Crossref
Bruno Neves, Carolina Andrade & Pedro Cravo. (2015) Natural Products as Leads in Schistosome Drug Discovery. Molecules 20:2, pages 1872-1903.
Crossref
Zhi-Kui Nie, Zhong-Tao Deng, Ai-Hui Zhang, Xiao-Jun Ji & He Huang. (2013) Efficient arachidonic acid-rich oil production by Mortierella alpina through a three-stage fermentation strategy. Bioprocess and Biosystems Engineering 37:3, pages 505-511.
Crossref

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