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Critical Reviews in Biotechnology Volume 36, 2016 - Issue 4
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Review Article

Expression of recombinant protein using Corynebacterium Glutamicum: progress, challenges and applications

Xiuxia LiuNational Engineering Laboratory of Cereal Fermentation Technology, School of Biotechnology, JiangNan University, Wuxi, China and
,
Yankun YangNational Engineering Laboratory of Cereal Fermentation Technology, School of Biotechnology, JiangNan University, Wuxi, China and
,
Wei ZhangNational Engineering Laboratory of Cereal Fermentation Technology, School of Biotechnology, JiangNan University, Wuxi, China and
,
Yang SunNational Engineering Laboratory of Cereal Fermentation Technology, School of Biotechnology, JiangNan University, Wuxi, China and
,
Feng PengNational Engineering Laboratory of Cereal Fermentation Technology, School of Biotechnology, JiangNan University, Wuxi, China and
,
Laura JeffreyInstitute of Pharmacy & Biomedical Sciences, Strathclyde University, Glasgow, UK
,
Linda HarveyInstitute of Pharmacy & Biomedical Sciences, Strathclyde University, Glasgow, UK
,
Brian McNeilInstitute of Pharmacy & Biomedical Sciences, Strathclyde University, Glasgow, UKCorrespondence[email protected]
&
Zhonghu BaiNational Engineering Laboratory of Cereal Fermentation Technology, School of Biotechnology, JiangNan University, Wuxi, China and Correspondence[email protected]
 show all
Pages 652-664 | Received 02 Jul 2014, Accepted 15 Dec 2014, Published online: 25 Feb 2015

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Dongbang Yao, Kang Zhang & Jing Wu. (2020) Available strategies for improved expression of recombinant proteins in Brevibacillus expression system: a review. Critical Reviews in Biotechnology 40:7, pages 1044-1058.
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Yujue Wang, Qiang Wang, Aobo Sha, Kexin Ren, Mengkai Hu, Meijuan Xu, Xian Zhang & Zhiming Rao. (2023) Advances in Synthetic Biology Techniques and Industrial Applications of Corynebacterium glutamicum. Fermentation 9:8, pages 729.
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Xiuxia Liu, Manman Sun, Alex Xiong Gao, Rodrigo Ledesma-Amaro, Qiuwu FangYankun Yang & Zhonghu Bai. (2023) Leaderless Bicistronic Design for Precise and Reliable Control of Gene Expression in Corynebacterium Glutamicum . ACS Synthetic Biology 12:7, pages 2157-2167.
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Wei Zhang & Tianwen Wang. (2023) Understanding Protein Functions in the Biological Context. Protein & Peptide Letters 30:6, pages 449-458.
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Mengmeng Wang, Zhong Shi, Ning Gao, Yingyu Zhou, Xiaomeng Ni, Jiuzhou Chen, Jiao Liu, Wenjuan Zhou, Xuan Guo, Bo Xin, Yanbing Shen, Yu Wang, Ping Zheng & Jibin Sun. (2023) Sustainable and high-level microbial production of plant hemoglobin in Corynebacterium glutamicum. Biotechnology for Biofuels and Bioproducts 16:1.
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Gi Yeon Kim, Jinyoung Kim, Geunyung Park, Hyeon Jin Kim, Jina Yang & Sang Woo Seo. (2023) Synthetic biology tools for engineering Corynebacterium glutamicum. Computational and Structural Biotechnology Journal 21, pages 1955-1965.
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Kerui Lin, Shuangyan Han & Suiping Zheng. (2022) Application of Corynebacterium glutamicum engineering display system in three generations of biorefinery. Microbial Cell Factories 21:1.
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Xinyu Yu, Shuang Li, Huibao Feng, Xihao Liao, Xin-Hui Xing, Zhonghu Bai, Xiuxia Liu & Chong Zhang. (2022) CRISPRi-microfluidics screening enables genome-scale target identification for high-titer protein production and secretion. Metabolic Engineering.
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Seong Min Lee & Ki Jun Jeong. (2022) Advances in Synthetic Biology Tools and Engineering of Corynebacterium glutamicum as a Platform Host for Recombinant Protein Production. Biotechnology and Bioprocess Engineering.
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Zaiwei Man, Huihui Cui, Jin Li, Zhiqiang Cai & Jing Guo. (2022) Production of Trehalose from Maltose by Whole Cells of Permeabilized Recombinant Corynebacterium glutamicum. Processes 10:12, pages 2501.
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Dirk Kiefer, Lea Rahel Tadele, Lars Lilge, Marius Henkel & Rudolf Hausmann. (2022) High‐level recombinant protein production with Corynebacterium glutamicum using acetate as carbon source . Microbial Biotechnology 15:11, pages 2744-2757.
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Meijuan Xu, Hui Gao, Zhenfeng Ma, Jin Han, Keyi Zheng, Minglong Shao & Zhiming Rao. (2022) Development of a 2-pyrrolidone biosynthetic pathway in Corynebacterium glutamicum by engineering an acetyl-CoA balance route. Amino Acids 54:11, pages 1437-1450.
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Xinyu Yu, Xiuxia Liu, Xiong Gao, Xunxun Luo, Yankun Yang, Ye Li, Chunli Liu, Chong Zhang & Zhonghu Bai. (2022) Development of a novel platform for recombinant protein production in Corynebacterium glutamicum on ethanol. Synthetic and Systems Biotechnology 7:2, pages 765-774.
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Seong-Jin Hong, Bo-Ram Park, Ha-Nul Lee, Da Eun Jang, Hye-Jin Kang, Kashif Ameer, Soo-Jung Kim & Young-Min Kim. (2022) Carbohydrate-binding module of cycloisomaltooligosaccharide glucanotransferase from Thermoanaerobacter thermocopriae improves its cyclodextran production. Enzyme and Microbial Technology 157, pages 110023.
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Manman Sun, Alex Xiong Gao, Rodrigo Ledesma-Amaro, An Li, Rongbin Wang, Jianqi Nie, Pei Zheng, Yankun Yang, Zhonghu Bai & Xiuxia Liu. (2022) Hypersecretion of OmlA antigen in Corynebacterium glutamicum through high-throughput based development process. Applied Microbiology and Biotechnology 106:8, pages 2953-2967.
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Qing Jin, Fang Pan, Chun-Fei Hu, Sang Yup Lee, Xiao-Xia Xia & Zhi-Gang Qian. (2022) Secretory production of spider silk proteins in metabolically engineered Corynebacterium glutamicum for spinning into tough fibers. Metabolic Engineering 70, pages 102-114.
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Jian Wang, Xuesong Wang, Qing Liang, Deheng Li, Dawei Li & Qunqun Guo. (2021) Transcriptome analysis of l-leucine-producing Corynebacterium glutamicum under the addition of trimethylglycine. Amino Acids 54:2, pages 229-240.
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Shuanghong Zhang, Dingyu Liu, Zhitao Mao, Yufeng Mao, Hongwu Ma, Tao Chen, Xueming Zhao & Zhiwen Wang. (2018) Model-based reconstruction of synthetic promoter library in Corynebacterium glutamicum. Biotechnology Letters 40:5, pages 819-827.
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