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Review Article

Molecular mechanisms of drug resistance and its reversal in cancer

, &
Pages 716-726 | Received 05 Oct 2013, Accepted 21 Dec 2014, Published online: 11 Mar 2015

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Brian Kawahara, Kym F. Faull, Carla Janzen & Pradip K. Mascharak. (2021) Carbon Monoxide Inhibits Cytochrome P450 Enzymes CYP3A4/2C8 in Human Breast Cancer Cells, Increasing Sensitivity to Paclitaxel. Journal of Medicinal Chemistry 64:12, pages 8437-8446.
Crossref
Maolin Ge, Qiongyu Xu, Ting Kang, Dan Li, Ruiheng Wang, Zhihong Chen, Shufeng Xie, Wenbin Wang & Han Liu. (2021) Deubiquitinating enzyme inhibitor alleviates cyclin A1‐mediated proteasome inhibitor tolerance in mixed‐lineage leukemia. Cancer Science 112:6, pages 2287-2298.
Crossref
Ming Wu, Yujie Zhao, Nanxi Peng, Zuo Tao & Bo Chen. (2021) Identification of chemoresistance-associated microRNAs and hub genes in breast cancer using bioinformatics analysis. Investigational New Drugs 39:3, pages 705-712.
Crossref
Nirmala Tilija Pun & Chul-Ho Jeong. (2021) Statin as a Potential Chemotherapeutic Agent: Current Updates as a Monotherapy, Combination Therapy, and Treatment for Anti-Cancer Drug Resistance. Pharmaceuticals 14:5, pages 470.
Crossref
Wookyeom Yang, Dasol Kim, Dae Kyoung Kim, Kyung Un Choi, Dong Soo Suh & Jae Ho Kim. (2021) Therapeutic Strategies for Targeting Ovarian Cancer Stem Cells. International Journal of Molecular Sciences 22:10, pages 5059.
Crossref
Run-Ze Chen, Fei Yang, Min Zhang, Zhi-Gang Sun & Nan Zhang. (2021) Cellular and Molecular Mechanisms of Pristimerin in Cancer Therapy: Recent Advances. Frontiers in Oncology 11.
Crossref
Masood Alam Khan. (2021) Targeted Drug Delivery Using Tuftsin-bearing Liposomes: Implications in the Treatment of Infectious Diseases and Tumors. Current Drug Targets 22:7, pages 770-778.
Crossref
Siyao Dong, Chengyan Song, Baocui Qi, Xiaochen Jiang, Lu Liu & Yan Xu. (2021) Strongly preserved modules between cancer tissue and cell line contribute to drug resistance analysis across multiple cancer types. Genomics 113:3, pages 1026-1036.
Crossref
Roman V. Lenchine, Sushma R. Rao, Xuemin Wang, Danielle Meiwen Fang & Christopher G. Proud. (2021) Elongation factor eEF2 kinase and autophagy jointly promote survival of cancer cells. Biochemical Journal 478:8, pages 1547-1569.
Crossref
Raúl Ortíz, Francisco Quiñonero, Beatriz García-Pinel, Marco Fuel, Cristina Mesas, Laura Cabeza, Consolación Melguizo & Jose Prados. (2021) Nanomedicine to Overcome Multidrug Resistance Mechanisms in Colon and Pancreatic Cancer: Recent Progress. Cancers 13:9, pages 2058.
Crossref
Ting Wang, Jingjing Dong, Xu Yuan, Haotian Wen, Linguangjin Wu, Jianwen Liu, Hua Sui & Wanli Deng. (2021) A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression. Frontiers in Pharmacology 12.
Crossref
Yushu Huang, Yang He, Xiaoyan Xia, Hao Quan & Jiahui Yu. (2021) Phenylboronic acid-functionalized co-delivery micelles with synergistic effect and down-regulation of HIF-1alpha to overcome multidrug resistance. Journal of Drug Delivery Science and Technology 62, pages 102346.
Crossref
Balaram Ghosh & Swati Biswas. (2021) Polymeric micelles in cancer therapy: State of the art. Journal of Controlled Release 332, pages 127-147.
Crossref
Ya-Sheng Li, Xi Yang, Dong-Sheng Zhao, Yue Cai, Zhi Huang, Rui Wu, Si-Jia Wang, Gui-Jun Liu, Jian Wang, Xiao-Ze Bao, Xin-Yi Ye, Bin Wei, Zi-Ning Cui & Hong Wang. (2021) Design, synthesis and bioactivity study on 5-phenylfuran derivatives as potent reversal agents against P-glycoprotein-mediated multidrug resistance in MCF-7/ADR cell. European Journal of Medicinal Chemistry 216, pages 113336.
Crossref
Anna Choromańska, Agnieszka Chwiłkowska, Julita Kulbacka, Dagmara Baczyńska, Nina Rembiałkowska, Anna Szewczyk, Olga Michel, Agnieszka Gajewska-Naryniecka, Dawid Przystupski & Jolanta Saczko. (2021) Modifications of Plasma Membrane Organization in Cancer Cells for Targeted Therapy. Molecules 26:7, pages 1850.
Crossref
Chao Dong, Jiao Wu, Yin Chen, Jianyun Nie & Ceshi Chen. (2021) Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer. Frontiers in Pharmacology 12.
Crossref
Ming Li & Xiaoying Zhang. (2021) BRAF Mutations and Resistance of Non-Small Cell Lung Cancer to BRAF-Targeted Therapies Using Liquid Biopsy. Asia-Pacific Journal of Oncology Nursing 8:2, pages 110-111.
Crossref
Prarthna Yadav, Harshita Mishra, Manju Nagpal & Geeta Aggarwal. (2021) Expanding Opportunities in Treatment of Leukemia by Solid Lipid Nanoparticles. Letters in Drug Design & Discovery 18:3, pages 212-221.
Crossref
Danfeng Xue, Xiongming Zhou & Jiaxuan Qiu. (2021) Cytotoxicity mechanisms of plumbagin in drug-resistant tongue squamous cell carcinoma. Journal of Pharmacy and Pharmacology 73:1, pages 98-109.
Crossref
Maolin Ge, Zhi Qiao, Yan Kong, Hongyu Liang, Yan Sun, Hui Lu, Zhenshu Xu & Han Liu. (2020) Modulating proteasome inhibitor tolerance in multiple myeloma: an alternative strategy to reverse inevitable resistance. British Journal of Cancer 124:4, pages 770-776.
Crossref
María Paula Ceballos, Antonella Angel, Carla Beatriz Delprato, Verónica Inés Livore, Anabela Cecilia Ferretti, Alvaro Lucci, Carla Gabriela Comanzo, María de Luján Alvarez, Ariel Darío Quiroga, Aldo Domingo Mottino & María Cristina Carrillo. (2021) Sirtuin 1 and 2 inhibitors enhance the inhibitory effect of sorafenib in hepatocellular carcinoma cells. European Journal of Pharmacology 892, pages 173736.
Crossref
Xuehua Luo, Huijun Xie, Li Han, Qiaoming Zhong, Meng Xu & Ling Jin. (2021) Integrated Network Pharmacology and Molecular Docking to Reveal the Mechanism of Tetrandrine in Tumor Chemoresistance. Oncologie 23:3, pages 425-438.
Crossref
Yanxia Zhao & Weifa Zheng. (2021) Deciphering the antitumoral potential of the bioactive metabolites from medicinal mushroom Inonotus obliquus. Journal of Ethnopharmacology 265, pages 113321.
Crossref
Ruxue Jia, Hu Zhao & Shuiliang Wang. 2021. Tumor Microenvironment. Tumor Microenvironment 1 29 .
Hang Zhang, Haiwei Xu, Charles R. AshbyJr.Jr., Yehuda G. Assaraf, Zhe‐Sheng Chen & Hong‐Min Liu. (2020) Chemical molecular‐based approach to overcome multidrug resistance in cancer by targeting P‐glycoprotein (P‐gp). Medicinal Research Reviews 41:1, pages 525-555.
Crossref
Xinhua Xi, Yongzheng Bao, Yangfan Zhou, Yu Chen, Xueren Zhong, Junjian Liao, Jun Zhou, Sitao Xu, Ziye Cao, Konghe Hu, Yongyu Hu, Xiaolong He, Longze Zhou, Hongsheng Lin & Qiang Wu. (2020) Oncogenic gene TRIM10 confers resistance to cisplatin in osteosarcoma cells and activates the NF‐κB signaling pathway. Cell Biology International 45:1, pages 74-82.
Crossref
Qie Guo, Xiao Li, Meng-Na Cui, Jia-Lin Sun, Hong-Yan Ji, Bei-Bei Ni & Mei-Xing Yan. (2020) CD13: A Key Player in Multidrug Resistance in Cancer Chemotherapy. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 28:5, pages 533-540.
Crossref
Peng Yang, Wen Liu, Rong Fu, Guo-bin Ding, Sajid Amin & Zhuoyu Li. (2020) Cucurbitacin E Chemosensitizes Colorectal Cancer Cells via Mitigating TFAP4/Wnt/β-Catenin Signaling. Journal of Agricultural and Food Chemistry 68:48, pages 14148-14160.
Crossref
Yuanming Jing, Wenqing Liang, Jian Liu, Lin Zhang, Jianguo Wei, Jianhui Yang, Yu Zhang & Zongliang Huang. (2020) Autophagy-mediating microRNAs in cancer chemoresistance. Cell Biology and Toxicology 36:6, pages 517-536.
Crossref
Maria Papatsirou, Pinelopi I Artemaki, Andreas Scorilas & Christos K Kontos. (2020) The role of circular RNAs in therapy resistance of patients with solid tumors. Personalized Medicine 17:6, pages 469-490.
Crossref
Maryam Akbarzadeh, Shabnam Akbarzadeh & Maryam Majidinia. (2020) Targeting Notch signaling pathway as an effective strategy in overcoming drug resistance in ovarian cancer. Pathology - Research and Practice 216:11, pages 153158.
Crossref
Katja Zappe & Margit Cichna-Markl. (2020) Aberrant DNA Methylation of ABC Transporters in Cancer. Cells 9:10, pages 2281.
Crossref
Xing-Duo Dong, Meng Zhang, Xiubin Ma, Jing-Quan Wang, Zi-Ning Lei, Qiu-Xu Teng, Yi-Dong Li, Lusheng Lin, Weiguo Feng & Zhe-Sheng Chen. (2020) Bruton’s Tyrosine Kinase (BTK) Inhibitor RN486 Overcomes ABCB1-Mediated Multidrug Resistance in Cancer Cells. Frontiers in Cell and Developmental Biology 8.
Crossref
Lili Duan, Jiaojiao Ma, Wanli Yang, Lu Cao, Xiaoqian Wang, Liaoran Niu, Yiding Li, Wei Zhou, Yujie Zhang, Jinqiang Liu, Hongwei Zhang, Qingchuan Zhao, Liu Hong & Daiming Fan. (2020) EI24 Inhibits Cell Proliferation and Drug Resistance of Esophageal Squamous Cell Carcinoma. Frontiers in Oncology 10.
Crossref
Lei GaoPeiran ZhaoYang LiDawei YangPing HuLianzhi LiYufeng ChengHengchen Yao. (2020) Reversal of P-glycoprotein-mediated multidrug resistance by novel curcumin analogues in paclitaxel-resistant human breast cancer cells. Biochemistry and Cell Biology 98:4, pages 484-491.
Crossref
Zhuo‐Xun Wu, Yuqi Yang, Guangsuo Wang, Jing‐Quan Wang, Qiu‐Xu Teng, Lingling Sun, Zi‐Ning Lei, Lizhu Lin, Zhe‐Sheng Chen & Chang Zou. (2020) Dual TTK/CLK2 inhibitor, CC‐671, selectively antagonizes ABCG2‐mediated multidrug resistance in lung cancer cells. Cancer Science 111:8, pages 2872-2882.
Crossref
Meng Zhang, Xuan-Yu Chen, Xing-Duo Dong, Jing-Quan Wang, Weiguo Feng, Qiu-Xu Teng, Qingbin Cui, Jing Li, Xiang-Qi Li & Zhe-Sheng Chen. (2020) NVP-CGM097, an HDM2 Inhibitor, Antagonizes ATP-Binding Cassette Subfamily B Member 1-Mediated Drug Resistance. Frontiers in Oncology 10.
Crossref
Yi-Dong Li, Yong Mao, Xing-Duo Dong, Zi-Ning Lei, Yuqi Yang, Lizhu Lin, Charles R. AshbyJr.Jr., Dong-Hua Yang, Ying-Fang Fan & Zhe-Sheng Chen. (2020) Methyl-Cantharidimide (MCA) Has Anticancer Efficacy in ABCB1- and ABCG2-Overexpressing and Cisplatin Resistant Cancer Cells. Frontiers in Oncology 10.
Crossref
Weiguo Feng, Meng Zhang, Zhuo-Xun Wu, Jing-Quan Wang, Xing-Duo Dong, Yuqi Yang, Qiu-Xu Teng, Xuan-Yu Chen, Qingbin Cui & Dong-Hua Yang. (2020) Erdafitinib Antagonizes ABCB1-Mediated Multidrug Resistance in Cancer Cells. Frontiers in Oncology 10.
Crossref
Hairui Wang & Yongzhuo Huang. (2020) Combination therapy based on nano codelivery for overcoming cancer drug resistance. Medicine in Drug Discovery 6, pages 100024.
Crossref
Pei Zhang, Surong Zhao, Xingyue Lu, Zongfen Shi, Hao Liu & Bing Zhu. (2020) Metformin enhances the sensitivity of colorectal cancer cells to cisplatin through ROS-mediated PI3K/Akt signaling pathway. Gene 745, pages 144623.
Crossref
Yao Ma, Dawei Yin, Jingjia Ye, Xiduan Wei, Yameng Pei, Xueyuan Li, Guangxu Si, Xuan-Yu Chen, Zhe-Sheng Chen, Yi Dong, Feng Zou, Wei Shi, Qianqian Qiu, Hai Qian & Gang Liu. (2020) Discovery of Potent Inhibitors against P-Glycoprotein-Mediated Multidrug Resistance Aided by Late-Stage Functionalization of a 2-(4-(Pyridin-2-yl)phenoxy)pyridine Analogue. Journal of Medicinal Chemistry 63:10, pages 5458-5476.
Crossref
Absarul Haque, Khalid Hussain Wali Sait, Qamre Alam, Mohammad Zubair Alam, Nisreen Anfinan, Abdul Wahab Noor Wali & Mahmood Rasool. (2020) MDR1 Gene Polymorphisms and Its Association With Expression as a Clinical Relevance in Terms of Response to Chemotherapy and Prognosis in Ovarian Cancer. Frontiers in Genetics 11.
Crossref
Danuta Kuzajewska, Agata Wszołek, Wojciech Żwierełło, Lucyna Kirczuk & Agnieszka Maruszewska. (2020) Magnetotactic Bacteria and Magnetosomes as Smart Drug Delivery Systems: A New Weapon on the Battlefield with Cancer?. Biology 9:5, pages 102.
Crossref
Hongyu Tao, Ling Zuo, Huanli Xu, Cong Li, Gan Qiao, Mingyue Guo & Xiukun Lin. (2020) Alkaloids as Anticancer Agents: A Review of Chinese Patents in Recent 5 Years. Recent Patents on Anti-Cancer Drug Discovery 15:1, pages 2-13.
Crossref
Yuqi Yang, Ning Ji, Qiu-Xu Teng, Chao-Yun Cai, Jing-Quan Wang, Zhuo-Xun Wu, Zi-Ning Lei, Sabrina Lusvarghi, Suresh V. Ambudkar & Zhe-Sheng Chen. (2020) Sitravatinib, a Tyrosine Kinase Inhibitor, Inhibits the Transport Function of ABCG2 and Restores Sensitivity to Chemotherapy-Resistant Cancer Cells in vitro. Frontiers in Oncology 10.
Crossref
Zhuo-Xun Wu, Zheng Peng, Yuqi Yang, Jing-Quan Wang, Qiu-Xu Teng, Zi-Ning Lei, Yi-Ge Fu, Ketankumar Patel, Lili Liu, Lizhu Lin, Chang Zou & Zhe-Sheng Chen. (2020) M3814, a DNA-PK Inhibitor, Modulates ABCG2-Mediated Multidrug Resistance in Lung Cancer Cells. Frontiers in Oncology 10.
Crossref
Xiaoyu Zhang, Weibin Chen, Jie Bai, Lijun Jin, Xiaoning Kang, Hui Zhang & Zunyi Wang. (2020) Pluronic P123 modified nano micelles loaded with doxorubicin enhanced tumor-suppressing effect on drug-resistant breast cancer cells. Aging 12:9, pages 8289-8300.
Crossref
Liyun Luo, Jianlei Zhang, Hailin Tang, Dongfeng Zhai, Danqing Huang, Li Ling, Xiaorong Wang, Ting Liu, Qiong Zhang, Zhijie Zhang, Zhimin He & Guopei Zheng. (2020) LncRNA SNORD3A specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression. Cell Death & Disease 11:5.
Crossref
Yifan Guo, Bin Li, Xu Yan, Xinming Shen, Juan Ma, Sijin Liu & Daoqiang Zhang. (2020) Bisphenol A and polychlorinated biphenyls enhance the cancer stem cell properties of human ovarian cancer cells by activating the WNT signaling pathway. Chemosphere 246, pages 125775.
Crossref
Francisco V.C. Mello, Gabriela N. de Moraes, Raquel C. Maia, Jennifer Kyeremateng, Surtaj Hussain Iram & Ralph Santos-Oliveira. (2020) The Effect of Nanosystems on ATP-Binding Cassette Transporters: Understanding the Influence of Nanosystems on Multidrug Resistance Protein-1 and P-glycoprotein. International Journal of Molecular Sciences 21:7, pages 2630.
Crossref
Maolin Ge, Zhi Qiao, Yan Kong, Hui Lu & Han Liu. (2020) Exosomes mediate intercellular transfer of non–autonomous tolerance to proteasome inhibitors in mixed‐lineage leukemia. Cancer Science 111:4, pages 1279-1290.
Crossref
Qiang Gao, Xiu-xiu Li, Yi-ming Xu, Jin-zhao Zhang, Shi-di Rong, Yan-qing Qin & Jing Fang. (2020) IRE1α-targeting downregulates ABC transporters and overcomes drug resistance of colon cancer cells. Cancer Letters 476, pages 67-74.
Crossref
Shengliang Liao, Xiaoping Rao, Minggui Shen, Hongyan Si, Jie Song, Shibin Shang & Zhanqian Song. (2020) New Hybrids Derived from the Natural Compound (-)-β-Pinene and Amides or Acylthioureas as Antitumor Agents. Letters in Drug Design & Discovery 17:3, pages 271-284.
Crossref
Danfeng Xue, Shu-Ting Pan, Xiongming Zhou, Fangfei Ye, Qun Zhou, Fanzhe Shi, Fei He, Hui Yu & Jiaxuan Qiu. (2020) Plumbagin Enhances the Anticancer Efficacy of Cisplatin by Increasing Intracellular ROS in Human Tongue Squamous Cell Carcinoma. Oxidative Medicine and Cellular Longevity 2020, pages 1-21.
Crossref
Jian Zhao, Xingyang Xue, Wenfan Fu, Lu Dai, Zeyong Jiang, Shengpeng Zhong, Boyun Deng & Jun Yin. (2020) Epigenetic activation of FOXF1 confers cancer stem cell properties to cisplatin‑resistant non‑small cell lung cancer. International Journal of Oncology.
Crossref
Zhuo-Xun Wu, Yuqi Yang, Qiu-Xu Teng, Jing-Quan Wang, Zi-Ning Lei, Jing-Qiu Wang, Sabrina Lusvarghi, Suresh Ambudkar, Dong-Hua Yang & Zhe-Sheng Chen. (2020) Tivantinib, A c-Met Inhibitor in Clinical Trials, Is Susceptible to ABCG2-Mediated Drug Resistance. Cancers 12:1, pages 186.
Crossref
Yaron Ilan & Zachary Spigelman. (2020) Establishing patient-tailored variability-based paradigms for anti-cancer therapy: Using the inherent trajectories which underlie cancer for overcoming drug resistance. Cancer Treatment and Research Communications 25, pages 100240.
Crossref
Lin Chang, Yulan Hou, Lili Zhu, Zhixue Wang, Guotao Chen, Chengfeng Shu & Yali Liu. (2020) Veliparib overcomes multidrug resistance in liver cancer cells. Biochemical and Biophysical Research Communications 521:3, pages 596-602.
Crossref
Livia Neves Borgheti-Cardoso, Juliana Santos Rosa Viegas, Ana Vitoria Pupo Silvestrini, Angelo Luis Caron, Fabiola Garcia Praça, Marcelo Kravicz & Maria Vitória Lopes Badra Bentley. (2020) Nanotechnology approaches in the current therapy of skin cancer. Advanced Drug Delivery Reviews 153, pages 109-136.
Crossref
Frederik Otzen Bagger & Victoria Probst. 2020. Single-cell Sequencing and Methylation. Single-cell Sequencing and Methylation 175 193 .
Morteza Ghandadi, Reza Valadan, Hamidreza Mohammadi, Javad Akhtari, Shabanali Khodashenas & Sorour Ashari. (2019) Wnt-β-catenin Signaling Pathway, the Achilles' Heels of Cancer Multidrug Resistance. Current Pharmaceutical Design 25:39, pages 4192-4207.
Crossref
Ruipu Sun, Ying Ying, Zhimin Tang, Ting Liu, Fuli Shi, Huixia Li, Taichen Guo, Shibo Huang & Ren Lai. (2019) The Emerging Role of the SLCO1B3 Protein in Cancer Resistance. Protein & Peptide Letters 27:1, pages 17-29.
Crossref
Yueqing Chen, Waiying Yvonne Tang, Xinyuan Tong & Hongbin Ji. (2019) Pathological transition as the arising mechanism for drug resistance in lung cancer. Cancer Communications 39:1, pages 53.
Crossref
Lu Jiang, Pan Wang, Ying-Jian Sun & Yi-Jun Wu. (2019) Ivermectin reverses the drug resistance in cancer cells through EGFR/ERK/Akt/NF-κB pathway. Journal of Experimental & Clinical Cancer Research 38:1.
Crossref
Anton V. Kolotaev, Karine R. Matevosyan, Vasiliy N. Osipov & Derenik S. Khachatryan. (2019) Synthesis of new quinazoline-containing hydroxamic acids as potential HDAC/VEGFR inhibitors. Unusual rearrangements with pyrrolidone ring opening and dehydration of 3-N-hydroxyquinazoline fragment containing tetracycles. Tetrahedron Letters 60:51, pages 151315.
Crossref
Innocensia Mokgohlwe Mangoato, Chandrashekara Puthanapura Mahadevappa & Motlalepula Gilbert Matsabisa. (2019) Cannabis sativa L. Extracts can reverse drug resistance in colorectal carcinoma cells in vitro. Synergy 9, pages 100056.
Crossref
Monica Marzagalli, Michela Raimondi, Fabrizio Fontana, Marina Montagnani Marelli, Roberta M. Moretti & Patrizia Limonta. (2019) Cellular and molecular biology of cancer stem cells in melanoma: Possible therapeutic implications. Seminars in Cancer Biology 59, pages 221-235.
Crossref
Wenji Zhang, Wenjuan Zhang, Lingli Sun, Limin Xiang, Xingfei Lai, Qiuhua Li & Shili Sun. (2019) The effects and mechanisms of epigallocatechin-3-gallate on reversing multidrug resistance in cancer. Trends in Food Science & Technology 93, pages 221-233.
Crossref
Philipp Ottis, Chiara Palladino, Phillip Thienger, Adrian Britschgi, Christian Heichinger, Marco Berrera, Alice Julien-Laferriere, Filip Roudnicky, Tony Kam-Thong, James R. Bischoff, Bruno Martoglio & Piergiorgio Pettazzoni. (2019) Cellular Resistance Mechanisms to Targeted Protein Degradation Converge Toward Impairment of the Engaged Ubiquitin Transfer Pathway. ACS Chemical Biology.
Crossref
Ryohei Maruhashi, Hiroaki Eguchi, Risa Akizuki, Shohei Hamada, Takumi Furuta, Toshiyuki Matsunaga, Satoshi Endo, Kenji Ichihara & Akira Ikari. (2019) Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells. Scientific Reports 9:1.
Crossref
Dongmei Fan, Linlin Jiang, Yuewen Song, Shiqi Bao, Yuanyuan Yang, Xiangfei Yuan, Yongsu Zhen, Ming Yang & Dongsheng Xiong. (2019) An Engineered Fusion Protein Anti-CD19(Fab)-LDM Effectively Inhibits ADR-Resistant B Cell Lymphoma. Frontiers in Oncology 9.
Crossref
Ana P. Francisco, Eduarda Mendes, Ana R. Santos & Maria J. Perry. (2019) Anticancer Triazenes: from Bioprecursors to Hybrid Molecules. Current Pharmaceutical Design 25:14, pages 1623-1642.
Crossref
Li Jia, Nan Jia, Yan Gao, Haiyang Hu, Xiuli Zhao, Dawei Chen & Mingxi Qiao. (2019) Multi-Modulation of Doxorubicin Resistance in Breast Cancer Cells by Poly(l-histidine)-Based Multifunctional Micelles. Pharmaceutics 11:8, pages 385.
Crossref
Elnaz Abbasifarid, Sayed Mahmoud Sajjadi-Jazi, Maryam Beheshtian, Hilda Samimi, Bagher Larijani & Vahid Haghpanah. (2019) The Role of ATP-Binding Cassette Transporters in the Chemoresistance of Anaplastic Thyroid Cancer: A Systematic Review. Endocrinology 160:8, pages 2015-2023.
Crossref
Amit Kumar & Vikas Jaitak. (2019) Natural products as multidrug resistance modulators in cancer. European Journal of Medicinal Chemistry 176, pages 268-291.
Crossref
Zhuo-Xun Wu, Qiu-Xu Teng, Chao-Yun Cai, Jing-Quan Wang, Zi-Ning Lei, Yuqi Yang, Ying-Fang Fan, Jian-Ye Zhang, Jun Li & Zhe-Sheng Chen. (2019) Tepotinib reverses ABCB1-mediated multidrug resistance in cancer cells. Biochemical Pharmacology 166, pages 120-127.
Crossref
Yue Pan, Yunqiu Zhang, Qing Chen, Xufeng Tao, Jianzhou Liu & Gary Guishan Xiao. (2019) CTAB Enhances Chemo-Sensitivity Through Activation of AMPK Signaling Cascades in Breast Cancer. Frontiers in Pharmacology 10.
Crossref
Ning Ji, Yuqi Yang, Chao-Yun Cai, Jing-Quan Wang, Zi-Ning Lei, Zhuo-Xun Wu, Qingbin Cui, Dong-Hua Yang, Zhe-Sheng Chen & Dexin Kong. (2019) Midostaurin Reverses ABCB1-Mediated Multidrug Resistance, an in vitro Study. Frontiers in Oncology 9.
Crossref
Hailing Duan, Zaixing Yang, Lan Liang & Xiangdong Zhou. (2019) CA916798 gene expression is associated with multidrug resistance and predicts progression‑free survival in patients with lung cancer. Oncology Letters.
Crossref
Ahmet Altay, Aysun Kılıc Suloglu, Gulcın Sagdıcoglu Celep, Guldenız Selmanoglu & Faruk Bozoglu. (2019) Anatolıan sage Salvıa frutıcosa ınhıbıts cytosolıc glutathıone-s-transferase actıvıty and colon cancer cell prolıferatıon. Journal of Food Measurement and Characterization 13:2, pages 1390-1399.
Crossref
María Paula Ceballos, Juan Pablo Rigalli, Lucila Inés Ceré, Mariana Semeniuk, Viviana Alicia Catania & María Laura Ruiz. (2019) ABC Transporters: Regulation and Association with Multidrug Resistance in Hepatocellular Carcinoma and Colorectal Carcinoma. Current Medicinal Chemistry 26:7, pages 1224-1250.
Crossref
Yan Gao, Li Jia, Qi Wang, Haiyang Hu, Xiuli Zhao, Dawei Chen & Mingxi Qiao. (2019) pH/Redox Dual-Responsive Polyplex with Effective Endosomal Escape for Codelivery of siRNA and Doxorubicin against Drug-Resistant Cancer Cells. ACS Applied Materials & Interfaces 11:18, pages 16296-16310.
Crossref
Zhu Kun‐Peng, Zhang Chun‐Lin, Ma Xiao‐Long & Zhang Lei. (2018) Fibronectin‐1 modulated by the long noncoding RNA OIP5‐AS1/miR‐200b‐3p axis contributes to doxorubicin resistance of osteosarcoma cells. Journal of Cellular Physiology 234:5, pages 6927-6939.
Crossref
Aynaz Mihanfar, Javad Aghazadeh Attari, Iraj Mohebbi, Maryam Majidinia, Mojtaba Kaviani, Mehdi Yousefi & Bahman Yousefi. (2018) Ovarian cancer stem cell: A potential therapeutic target for overcoming multidrug resistance. Journal of Cellular Physiology 234:4, pages 3238-3253.
Crossref
Laura Bayón-Cordero, Itziar Alkorta & Lide Arana. (2019) Application of Solid Lipid Nanoparticles to Improve the Efficiency of Anticancer Drugs. Nanomaterials 9:3, pages 474.
Crossref
Guang Huang, Jin-Yun Dong, Qi-Jing Zhang, Qing-Qing Meng, Hui-Ran Zhao, Bao-Quan Zhu & Shao-Shun Li. (2019) Discovery and synthesis of sulfur-containing 6-substituted 5,8-dimethoxy-1,4-naphthoquinone oxime derivatives as new and potential anti-MDR cancer agents. European Journal of Medicinal Chemistry 165, pages 160-171.
Crossref
Jingyi Yan, Didi Chen, Xiaolei Chen, Xuecheng Sun, Qiantong Dong, Changyuan Hu, Feng Zhou & Wei Chen. (2019) Downregulation of lncRNA CCDC26 contributes to imatinib resistance in human gastrointestinal stromal tumors through IGF-1R upregulation. Brazilian Journal of Medical and Biological Research 52:6.
Crossref
Ning Ji, Yuqi Yang, Chao-Yun Cai, Zi-Ning Lei, Jing-Quan Wang, Pranav Gupta, Suneet Shukla, Suresh V. Ambudkar, Dexin Kong & Zhe-Sheng Chen. (2019) Selonsertib (GS-4997), an ASK1 inhibitor, antagonizes multidrug resistance in ABCB1- and ABCG2-overexpressing cancer cells. Cancer Letters 440-441, pages 82-93.
Crossref
Anna Palko-Łabuz, Kamila Środa-Pomianek, Olga Wesołowska, Edyta Kostrzewa-Susłow, Anna Uryga & Krystyna Michalak. (2019) MDR reversal and pro-apoptotic effects of statins and statins combined with flavonoids in colon cancer cells. Biomedicine & Pharmacotherapy 109, pages 1511-1522.
Crossref
Mun Fai Loke & Aimi Hanafi. 2019. Encyclopedia of Bioinformatics and Computational Biology. Encyclopedia of Bioinformatics and Computational Biology 926 931 .
Ning Ji, Yuqi Yang, Zi-Ning Lei, Chao-Yun Cai, Jing-Quan Wang, Pranav Gupta, Xiaomeng Xian, Dong-Hua Yang, Dexin Kong & Zhe-Sheng Chen. (2018) Ulixertinib (BVD-523) antagonizes ABCB1- and ABCG2-mediated chemotherapeutic drug resistance. Biochemical Pharmacology 158, pages 274-285.
Crossref
Ning Ji, Yuqi Yang, Chao-Yun Cai, Zi-Ning Lei, Jing-Quan Wang, Pranav Gupta, Qiu-Xu Teng, Zhe-Sheng Chen, Dexin Kong & Dong-Hua Yang. (2018) VS-4718 Antagonizes Multidrug Resistance in ABCB1- and ABCG2-Overexpressing Cancer Cells by Inhibiting the Efflux Function of ABC Transporters. Frontiers in Pharmacology 9.
Crossref
Hiroaki Eguchi, Risa Akizuki, Ryohei Maruhashi, Mitsutoshi Tsukimoto, Takumi Furuta, Toshiyuki Matsunaga, Satoshi Endo & Akira Ikari. (2018) Increase in resistance to anticancer drugs involves occludin in spheroid culture model of lung adenocarcinoma A549 cells. Scientific Reports 8:1.
Crossref
Wei Zhang, Ying-Fang Fan, Chao-Yun Cai, Jing-Quan Wang, Qiu-Xu Teng, Zi-Ning Lei, Leli Zeng, Pranav Gupta & Zhe-Sheng Chen. (2018) Olmutinib (BI1482694/HM61713), a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses ABCG2-Mediated Multidrug Resistance in Cancer Cells. Frontiers in Pharmacology 9.
Crossref
Xing Zheng & Hongxia Li. (2018) TKTL1 modulates the response of paclitaxel-resistant human ovarian cancer cells to paclitaxel. Biochemical and Biophysical Research Communications 503:2, pages 572-579.
Crossref
Bo Wang, Li-Ying Ma, Jing-Quan Wang, Zi-Ning Lei, Pranav Gupta, Yuan-Di Zhao, Zhong-Hua Li, Ying Liu, Xin-Hui Zhang, Ya-Nan Li, Bing Zhao, Zhe-Sheng Chen & Hong-Min Liu. (2018) Discovery of 5-Cyano-6-phenylpyrimidin Derivatives Containing an Acylurea Moiety as Orally Bioavailable Reversal Agents against P-Glycoprotein-Mediated Mutidrug Resistance. Journal of Medicinal Chemistry 61:14, pages 5988-6001.
Crossref
Tiantian Qin, Weihua Liu, Junfeng Huo, Leilei Li, Xueyan Zhang, Xiaoli Shi, Jinlei Zhou & Cong Wang. (2018) SIRT1 expression regulates the transformation of resistant esophageal cancer cells via the epithelial-mesenchymal transition. Biomedicine & Pharmacotherapy 103, pages 308-316.
Crossref
Guan-Nan Zhang, Yun-Kai Zhang, Yi-Jun Wang, Pranav Gupta, Charles R. AshbyJr.Jr., Saeed Alqahtani, Tongjin Deng, Susan E. Bates, Amal Kaddoumi, John N.D. Wurpel, Yi-Xiong Lei & Zhe-Sheng Chen. (2018) Epidermal growth factor receptor (EGFR) inhibitor PD153035 reverses ABCG2-mediated multidrug resistance in non-small cell lung cancer: In vitro and in vivo. Cancer Letters 424, pages 19-29.
Crossref
Haidi Guan, Liucan Wang, Jixi Zhang, Yuxin Xing & Kaiyong Cai. (2018) Selective Enrichment of Polydopamine in Mesoporous Nanocarriers for Nuclear-Targeted Drug Delivery. Particle & Particle Systems Characterization 35:6, pages 1800011.
Crossref
Ying-Fang Fan, Wei Zhang, Leli Zeng, Zi-Ning Lei, Chao-Yun Cai, Pranav Gupta, Dong-Hua Yang, Qingbin Cui, Zuo-Dong Qin, Zhe-Sheng Chen & Louis D. Trombetta. (2018) Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters. Cancer Letters 421, pages 186-198.
Crossref
Risa Akizuki, Ryohei Maruhashi, Hiroaki Eguchi, Kazuki Kitabatake, Mitsutoshi Tsukimoto, Takumi Furuta, Toshiyuki Matsunaga, Satoshi Endo & Akira Ikari. (2018) Decrease in paracellular permeability and chemosensitivity to doxorubicin by claudin-1 in spheroid culture models of human lung adenocarcinoma A549 cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865:5, pages 769-780.
Crossref
Katarzyna Mieszala, Malgorzata Rudewicz, Agnieszka Gomulkiewicz, Katarzyna Ratajczak‑Wielgomas, Jedrzej Grzegrzolka, Piotr Dziegiel & Sylwia Borska. (2018) Expression of genes and proteins of multidrug resistance in gastric cancer cells treated with resveratrol. Oncology Letters.
Crossref
Chenwei Wu, Li Xu, Leilei Shi, Xihui Gao, Jing Li, Xinyuan Zhu & Chuan Zhang. (2018) Supramolecularly self-assembled nano-twin drug for reversing multidrug resistance. Biomaterials Science 6:8, pages 2261-2269.
Crossref

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