Publication Cover
Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 29, 2012 - Issue 9
1,577
Views
149
CrossRef citations to date
0
Altmetric
Research Papers

CLOCK, PER2 and BMAL1 DNA Methylation: Association with Obesity and Metabolic Syndrome Characteristics and Monounsaturated Fat Intake

, , , , &
Pages 1180-1194 | Received 25 May 2012, Accepted 31 Jul 2012, Published online: 24 Sep 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (16)

Salman A. Ahmadi, Joan E. Tranmer, Jennifer A. Ritonja, Lisa Flaten, Danai G. Topouza, Qing Ling Duan, Francine Durocher, Kristan J. Aronson & Parveen Bhatti. (2022) DNA methylation of circadian genes and markers of cardiometabolic risk in female hospital workers: An exploratory study. Chronobiology International 39:5, pages 735-746.
Read now
Lílian L. Lopes, Josefina Bressan, Maria do Carmo G. Peluzio & Helen Hermana M. Hermsdorff. (2019) LINE-1 in Obesity and Cardiometabolic Diseases: A Systematic Review. Journal of the American College of Nutrition 38:5, pages 478-484.
Read now
Mirian Samblas, Fermín I. Milagro & Alfredo Martínez. (2019) DNA methylation markers in obesity, metabolic syndrome, and weight loss. Epigenetics 14:5, pages 421-444.
Read now
Yue Wu, Karen E. Peterson, Brisa N. Sánchez, Dana C. Dolinoy, Adriana Mercado-Garcia, Martha M. Téllez-Rojo & Jaclyn M. Goodrich. (2018) Association of blood leukocyte DNA methylation at LINE-1 and growth-related candidate genes with pubertal onset and progression. Epigenetics 13:12, pages 1222-1233.
Read now
Susanne A. Bengesser, Eva Z. Reininghaus, Nina Lackner, Armin Birner, Frederike T. Fellendorf, Martina Platzer, Nora Kainzbauer, Bernhard Tropper, Christa Hörmanseder, Robert Queissner, Hans-Peter Kapfhammer, Sandra J. Wallner-Liebmann, Robert Fuchs, Erwin Petek, Christian Windpassinger, Mario Schnalzenberger, Bernd Reininghaus, Bernd Evert & Andreas Waha. (2018) Is the molecular clock ticking differently in bipolar disorder? Methylation analysis of the clock gene ARNTL. The World Journal of Biological Psychiatry 19:sup2, pages S21-S29.
Read now
Omar Ramos-Lopez, Mirian Samblas, Fermin I. Milagro, Jose I. Riezu-Boj, A.B. Crujeiras, J. Alfredo Martinez & MENA Project. (2018) Circadian gene methylation profiles are associated with obesity, metabolic disturbances and carbohydrate intake. Chronobiology International 35:7, pages 969-981.
Read now
Edyta Reszka, Edyta Wieczorek, Monika Przybek, Ewa Jabłońska, Paweł Kałużny, Agnieszka Bukowska-Damska, Shanbeh Zienolddiny & Beata Pepłońska. (2018) Circadian gene methylation in rotating-shift nurses: a cross-sectional study. Chronobiology International 35:1, pages 111-121.
Read now
Agnieszka Bukowska-Damska, Edyta Reszka, Pawel Kaluzny, Edyta Wieczorek, Monika Przybek, Shanbeh Zienolddiny & Beata Peplonska. (2018) Sleep quality and methylation status of selected tumor suppressor genes among nurses and midwives. Chronobiology International 35:1, pages 122-131.
Read now
Agnieszka Bukowska-Damska, Edyta Reszka, Pawel Kaluzny, Edyta Wieczorek, Monika Przybek, Shanbeh Zienolddiny & Beata Peplonska. (2017) Sleep quality and methylation status of core circadian rhythm genes among nurses and midwives. Chronobiology International 34:9, pages 1211-1223.
Read now
Sergi Sayols-Baixeras, Isaac Subirana, Alba Fernández-Sanlés, Mariano Sentí, Carla Lluís-Ganella, Jaume Marrugat & Roberto Elosua. (2017) DNA methylation and obesity traits: An epigenome-wide association study. The REGICOR study. Epigenetics 12:10, pages 909-916.
Read now
Sue Kim, Hye-Sun Lee, Hyun-Ki Park, John A. Linton, Ji-Won Lee & Hyangkyu Lee. (2017) Visceral adiposity and expression of clock genes in peripheral blood mononuclear cells: A pilot study. Chronobiology International 34:8, pages 1057-1066.
Read now
Guillermo A. Silva-Martínez, Dalia Rodríguez-Ríos, Yolanda Alvarado-Caudillo, Alejandro Vaquero, Manel Esteller, F. Javier Carmona, Sebastian Moran, Finn C. Nielsen, Marie Wickström-Lindholm, Katarzyna Wrobel, Kazimierz Wrobel, Gloria Barbosa-Sabanero, Silvio Zaina & Gertrud Lund. (2016) Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics 11:5, pages 321-334.
Read now
Stella Aslibekyan, Hassan S. Dashti, Toshiko Tanaka, Jin Sha, Luigi Ferrucci, Degui Zhi, Stefania Bandinelli, Ingrid B. Borecki, Devin M. Absher, Donna K. Arnett & Jose M. Ordovas. (2014) PRKCZ methylation is associated with sunlight exposure in a North American but not a Mediterranean population. Chronobiology International 31:9, pages 1034-1040.
Read now
Nicole M. Kettner, Chinenye A. Katchy & Loning Fu. (2014) Circadian gene variants in cancer. Annals of Medicine 46:4, pages 208-220.
Read now
Vanessa Derenji Ferreira de Mello, Leena Pulkkinen, Marianne Lalli, Marjukka Kolehmainen, Jussi Pihlajamäki & Matti Uusitupa. (2014) DNA methylation in obesity and type 2 diabetes. Annals of Medicine 46:3, pages 103-113.
Read now
Antonio Garcia-Rios, Francisco Jesus Gomez-Delgado, Marta Garaulet, Juan Francisco Alcala-Diaz, Francisco Javier Delgado-Lista, Carmen Marin, Oriol Alberto Rangel-Zuñiga, Fernando Rodriguez-Cantalejo, Purificacion Gomez-Luna, Jose Maria Ordovas, Francisco Perez-Jimenez, Jose Lopez-Miranda & Pablo Perez-Martinez. (2014) Beneficial effect of CLOCK gene polymorphism rs1801260 in combination with low-fat diet on insulin metabolism in the patients with metabolic syndrome. Chronobiology International 31:3, pages 401-408.
Read now

Articles from other publishers (133)

José Ordovás. 2024. Precision Nutrition. Precision Nutrition 43 60 .
Haeun Park, Hyunyu Jeon, Kyung Ju Lee, Choong-Gon Kim & Dayeon Shin. (2023) Seaweed intake modulates the association between VIPR2 variants and the incidence of metabolic syndrome in middle-aged Koreans . Food & Function 14:20, pages 9446-9456.
Crossref
Samantha Aurich, Luise Müller, Peter Kovacs & Maria Keller. (2023) Implication of DNA methylation during lifestyle mediated weight loss. Frontiers in Endocrinology 14.
Crossref
Tirah Galaya Jesse, Eda Becer & Rasime Kalkan. (2023) Identification of the Relationship Between DNA Methylation of Circadian Rhythm Genes and Obesity. Biochemical Genetics.
Crossref
Marica Franzago, Elisa Alessandrelli, Stefania Notarangelo, Liborio Stuppia & Ester Vitacolonna. (2023) Chrono-Nutrition: Circadian Rhythm and Personalized Nutrition. International Journal of Molecular Sciences 24:3, pages 2571.
Crossref
Heping Huang, Ce Gao, Shuai Wang, Fen Wu, Jinsong Wei & Jinrong Peng. (2023) Bulk RNA-seq and scRNA-seq analysis reveal an activation of immune response and compromise of secretory function in major salivary glands of obese mice. Computational and Structural Biotechnology Journal 21, pages 105-119.
Crossref
Francisco Javier Ruiz-Ojeda & Marta Garaulet. 2023. Encyclopedia of Human Nutrition. Encyclopedia of Human Nutrition 36 47 .
Antonello E. Rigamonti, Valentina Bollati, Chiara Favero, Benedetta Albetti, Diana Caroli, Alessandra De Col, Silvano G. Cella & Alessandro Sartorio. (2022) Changes in DNA Methylation of Clock Genes in Obese Adolescents after a Short-Term Body Weight Reduction Program: A Possible Metabolic and Endocrine Chrono-Resynchronization. International Journal of Environmental Research and Public Health 19:23, pages 15492.
Crossref
Priyadarshni Patel, Vaithinathan Selvaraju, Jeganathan Ramesh Babu, Xu Wang & Thangiah Geetha. (2022) Racial Disparities in Methylation of NRF1, FTO, and LEPR Gene in Childhood Obesity. Genes 13:11, pages 2030.
Crossref
Zhengmei Fang, Lijun Zhu, Tao Zhang, Yuelong Jin, Yan Chen & Yingshui Yao. (2022) Sex-specific genetic association of brain and muscle Arnt-like protein-1 (BMAL1) and obesity in Chinese youth. Obesity Research & Clinical Practice 16:6, pages 464-469.
Crossref
Ludovica Verde, Luigi Barrea, Claudia Vetrani, Evelyn Frias-Toral, Sebastián Pablo Chapela, Ranil Jayawardena, Giulia de Alteriis, Annamaria Docimo, Silvia Savastano, Annamaria Colao & Giovanna Muscogiuri. (2022) Chronotype and Sleep Quality in Obesity: How Do They Change After Menopause?. Current Obesity Reports 11:4, pages 254-262.
Crossref
N. R. C. Wilson, Olivia J. Veatch & Steven M. Johnson. (2022) On the Relationship between Diabetes and Obstructive Sleep Apnea: Evolution and Epigenetics. Biomedicines 10:3, pages 668.
Crossref
Sanjeev Rana, Shafat Ali, Hilal Ahmad Wani, Qazi Danish Mushtaq, Swarkar Sharma & Muneeb U Rehman. (2022) Metabolic syndrome and underlying genetic determinants-A systematic review. Journal of Diabetes & Metabolic Disorders 21:1, pages 1095-1104.
Crossref
Luigi BARREA, Evelyn FRIAS-TORAL, Sara APRANO, Bianca CASTELLUCCI, Gabriella PUGLIESE, Dolores RODRIGUEZ-VEINTIMILLA, Giovanni VITALE, Davide GENTILINI, Annamaria COLAO, Silvia SAVASTANO & Giovanna MUSCOGIURI. (2022) The clock diet: a practical nutritional guide to manage obesity through chrononutrition. Minerva Medica 113:1.
Crossref
Huihui Jiang, Xin Yang, Miaomiao Mi, Xiaonan Wei, Hongyuan Wu, Yu Xin, Liping Jiao, Shengjun Sun & Chengming Sun. (2021) Development and performance evaluation of TaqMan real-time fluorescence quantitative methylation specific PCR for detecting methylation level of PER2. Molecular Biology Reports 49:3, pages 2097-2105.
Crossref
Priyadarshni PatelJeganathan Ramesh BabuXu WangThangiah Geetha. (2022) Role of macronutrient intake in the epigenetics of obesity. Biochemical Society Transactions 50:1, pages 487-497.
Crossref
Abeer M. Mahmoud. (2022) An Overview of Epigenetics in Obesity: The Role of Lifestyle and Therapeutic Interventions. International Journal of Molecular Sciences 23:3, pages 1341.
Crossref
Hui Han, Jinming Dou, Qingqing Hou & Huanjun Wang. (2022) Role of Circadian Rhythm and Impact of Circadian Rhythm Disturbance on the Metabolism and Disease. Journal of Cardiovascular Pharmacology 79:3, pages 254-263.
Crossref
Andrea G. Izquierdo, Paula M. Lorenzo & Ana B. Crujeiras. 2022. Epigenetics in Precision Medicine. Epigenetics in Precision Medicine 327 346 .
Bobbala Indumathi, Sai Satish Oruganti, Boddupally Sreenu & Vijay Kumar Kutala. (2020) Association of Promoter Methylation and Expression of Inflammatory Genes IL-6 and TNF-α with the Risk of Coronary Artery Disease in Diabetic and Obese Subjects among Asian Indians. Indian Journal of Clinical Biochemistry 37:1, pages 29-39.
Crossref
Nora Eszlari, Bence Bruncsics, Andras Millinghoffer, Gabor Hullam, Peter Petschner, Xenia Gonda, Gerome Breen, Peter Antal, Gyorgy Bagdy, John Francis William Deakin & Gabriella Juhasz. (2021) Biology of Perseverative Negative Thinking: The Role of Timing and Folate Intake. Nutrients 13:12, pages 4396.
Crossref
Whitney L. Do, Jazib Gohar, Lauren E. McCullough, Karla I. Galaviz, Karen N. Conneely & K. M. Venkat Narayan. (2021) Examining the association between adiposity and DNA methylation: A systematic review and meta‐analysis. Obesity Reviews 22:10.
Crossref
Sadashiv, Anupama Modi, Manoj Khokhar, Praveen Sharma, Rajnish Joshi, Sudhanshu Shekhar Mishra, Rajay N Bharshankar, Sunita Tiwari, Pankaj Kumar Singh, Vivek Vidyadhar Bhosale & Mahendra Pal Singh Negi. (2021) Leptin DNA Methylation and Its Association with Metabolic Risk Factors in a Northwest Indian Obese Population. Journal of Obesity & Metabolic Syndrome 30:3, pages 304-311.
Crossref
Henry J. Leese, Paul J. McKeegan & Roger G. Sturmey. (2021) Amino Acids and the Early Mammalian Embryo: Origin, Fate, Function and Life-Long Legacy. International Journal of Environmental Research and Public Health 18:18, pages 9874.
Crossref
Ivana Škrlec. 2021. Cardiac Diseases - Novel Aspects of Cardiac Risk, Cardiorenal Pathology and Cardiac Interventions. Cardiac Diseases - Novel Aspects of Cardiac Risk, Cardiorenal Pathology and Cardiac Interventions.
Harish Joshi, Basavaraj Vastrad, Nidhi Joshi, Chanabasayya Vastrad, Anandkumar Tengli & Iranna Kotturshetti. (2021) Identification of Key Pathways and Genes in Obesity Using Bioinformatics Analysis and Molecular Docking Studies. Frontiers in Endocrinology 12.
Crossref
Farha Ramzan, Mark H. Vickers & Richard F. Mithen. (2021) Epigenetics, microRNA and Metabolic Syndrome: A Comprehensive Review. International Journal of Molecular Sciences 22:9, pages 5047.
Crossref
Wenwen Tian, Ruyi Wang, Cunpei Bo, Yingjun Yu, Yuanyuan Zhang, Gyeong-Im Shin, Woe-Yeon Kim & Lei Wang. (2021) SDC mediates DNA methylation-controlled clock pace by interacting with ZTL in Arabidopsis . Nucleic Acids Research 49:7, pages 3764-3780.
Crossref
Francesc Ribas-Aulinas, Silvia Ribo, Marcela Parra-Vargas, Antonio Fernández-Pérez, Judith Cebrià, Maria Guardiola-Perello, Marta Ramon-Krauel, Carles Lerin, Ruben Diaz, Susana G. Kalko, Mario Vallejo, Antoni Díez-Noguera, Trinitat Cambras & Josep C. Jimenez-Chillaron. (2021) Neonatal overfeeding during lactation rapidly and permanently misaligns the hepatic circadian rhythm and programmes adult NAFLD. Molecular Metabolism 45, pages 101162.
Crossref
M.R. Lindley, B. Hussey, D.J. Hunter & S.S. Mastana. 2021. Epigenetics of Exercise and Sports. Epigenetics of Exercise and Sports 65 83 .
O. M. Drapkina & O. T. Kim. (2020) Epigenetics of obesity. Cardiovascular Therapy and Prevention 19:6, pages 2632.
Crossref
Giulia Tini, Vijayalakshmi Varma, Rosario Lombardo, Greg T. Nolen, Gregory Lefebvre, Patrick Descombes, Sylviane Métairon, Corrado Priami, Jim Kaput & Marie-Pier Scott-Boyer. (2020) DNA methylation during human adipogenesis and the impact of fructose. Genes & Nutrition 15:1.
Crossref
Yvonne Böttcher. (2020) Epigenetische Mechanismen bei Adipositas: Finetuning der Genaktivität durch DNA-Methylierung – Bertram-Preis 2020 – eine Kurzübersicht der Preisträgerin Yvonne Böttcher. Diabetologie und Stoffwechsel 15:06, pages 443-446.
Crossref
Ana Beatriz Rezende Paula, Denise de Coutinho Miranda, Franciane Toledo Nogueira, Ana Maria de Lauro Castrucci & Mauro César Isoldi. (2020) Does a high-fat diet affect the circadian clock, or is it the other way around? A systematic review. Nutrition Research 84, pages 1-13.
Crossref
Ann-Sofie Sundman, Fábio Pértille, Luiz Lehmann Coutinho, Elena Jazin, Carlos Guerrero-Bosagna & Per Jensen. (2020) DNA methylation in canine brains is related to domestication and dog-breed formation. PLOS ONE 15:10, pages e0240787.
Crossref
Arnaud Obri, Dolors Serra, Laura Herrero & Paula Mera. (2020) The role of epigenetics in the development of obesity. Biochemical Pharmacology 177, pages 113973.
Crossref
Moustafa Berrichi, Aziz Hichami, Lynda Addou-Klouche, Amira Sayed Khan & Naim Akhtar Khan. (2020) CD36 and GPR120 Methylation Associates with Orosensory Detection Thresholds for Fat and Bitter in Algerian Young Obese Children. Journal of Clinical Medicine 9:6, pages 1956.
Crossref
Rafael Silva Lima, Juliana Assis Silva Gomes & Paula Rocha Moreira. (2020) An overview about DNA methylation in childhood obesity: Characteristics of the studies and main findings. Journal of Cellular Biochemistry 121:5-6, pages 3042-3057.
Crossref
Michael Hudec, Pavlina Dankova, Roman Solc, Nardjas Bettazova & Marie Cerna. (2020) Epigenetic Regulation of Circadian Rhythm and Its Possible Role in Diabetes Mellitus. International Journal of Molecular Sciences 21:8, pages 3005.
Crossref
Lukas Schwingshackl, Jakub Morze & Georg Hoffmann. (2019) Mediterranean diet and health status: Active ingredients and pharmacological mechanisms. British Journal of Pharmacology 177:6, pages 1241-1257.
Crossref
Tatsunosuke Tomita & Yoshiaki Onishi. 2020. Chromatin and Epigenetics. Chromatin and Epigenetics.
Raian E. Contreras, Sonja C. Schriever & Paul T. Pfluger. (2019) Physiological and Epigenetic Features of Yoyo Dieting and Weight Control. Frontiers in Genetics 10.
Crossref
Heba F. Pasha, Randa H. Mohamed, Mostafa M. Toam & Ahmed M. Yehia. (2019) Genetic and epigenetic modifications of adiponectin gene: Potential association with breast cancer risk. The Journal of Gene Medicine 21:10.
Crossref
Dongmei Shi, Jie Chen, Jiaofeng Wang, Jianfeng Yao, Yiqin Huang, Gansheng Zhang & Zhijun Bao. (2019) Circadian Clock Genes in the Metabolism of Non-alcoholic Fatty Liver Disease. Frontiers in Physiology 10.
Crossref
Mohamad Yonis, Abraham Haim & A. Elsalam Zubidat. (2019) Altered metabolic and hormonal responses in male rats exposed to acute bright light-at-night associated with global DNA hypo-methylation. Journal of Photochemistry and Photobiology B: Biology 194, pages 107-118.
Crossref
Andrea G. Izquierdo & Ana B. Crujeiras. (2019) Obesity-Related Epigenetic Changes After Bariatric Surgery. Frontiers in Endocrinology 10.
Crossref
Hao Peng, Yun Zhu, Jack Goldberg, Viola Vaccarino & Jinying Zhao. (2019) DNA Methylation of Five Core Circadian Genes Jointly Contributes to Glucose Metabolism: A Gene-Set Analysis in Monozygotic Twins. Frontiers in Genetics 10.
Crossref
Zhenghe Wang, Jieyun Song, Yanhui Li, Bin Dong, Zhiyong Zou & Jun Ma. (2019) Early-Life Exposure to the Chinese Famine Is Associated with Higher Methylation Level in the INSR Gene in Later Adulthood. Scientific Reports 9:1.
Crossref
Kerstin Rohde, Maria Keller, Lars la Cour Poulsen, Matthias Blüher, Peter Kovacs & Yvonne Böttcher. (2019) Genetics and epigenetics in obesity. Metabolism 92, pages 37-50.
Crossref
Kunal Singh, Niraj Kumar Jha & Abhimanyu Thakur. (2019) Spatiotemporal chromatin dynamics - A telltale of circadian epigenetic gene regulation. Life Sciences 221, pages 377-391.
Crossref
Andrea G. Izquierdo & Ana B. Crujeiras. (2019) Role of epigenomic mechanisms in the onset and management of insulin resistance. Reviews in Endocrine and Metabolic Disorders 20:1, pages 89-102.
Crossref
Rachael C. Crew, Peter J. Mark & Brendan J. Waddell. 2019. Nutritional Epigenomics. Nutritional Epigenomics 211 229 .
Andrea G. Izquierdo & Ana B. Crujeiras. 2019. Prognostic Epigenetics. Prognostic Epigenetics 269 287 .
Behdokht Fathi Dizaji. (2018) The investigations of genetic determinants of the metabolic syndrome. Diabetes & Metabolic Syndrome: Clinical Research & Reviews 12:5, pages 783-789.
Crossref
Leonardo Vinícius Monteiro de Assis, Gabriela Sarti Kinker, Maria Nathália Moraes, Regina P. Markus, Pedro Augusto Fernandes & Ana Maria de Lauro Castrucci. (2018) Expression of the Circadian Clock Gene BMAL1 Positively Correlates With Antitumor Immunity and Patient Survival in Metastatic Melanoma. Frontiers in Oncology 8.
Crossref
Tim S. Nawrot, Nelly D. Saenen, Julie Schenk, Bram G. Janssen, Valeria Motta, Letizia Tarantini, Bianca Cox, Wouter Lefebvre, Charlotte Vanpoucke, Cristina Maggioni & Valentina Bollati. (2018) Placental circadian pathway methylation and in utero exposure to fine particle air pollution. Environment International 114, pages 231-241.
Crossref
M. Samblas, F. I. Milagro, M. L. Mansego, A. Marti & J. A. Martinez. (2018) PTPRS and PER3 methylation levels are associated with childhood obesity: results from a genome-wide methylation analysis . Pediatric Obesity 13:3, pages 149-158.
Crossref
Beatriz Vera, Hassan S. Dashti, Purificación Gómez-Abellán, Antonio M. Hernández-Martínez, Alberto Esteban, Frank A. J. L. Scheer, Richa Saxena & Marta Garaulet. (2018) Modifiable lifestyle behaviors, but not a genetic risk score, associate with metabolic syndrome in evening chronotypes. Scientific Reports 8:1.
Crossref
Mieke Van Hemelrijck & Sabine Rohrmann. 2018. Energy Balance and Prostate Cancer. Energy Balance and Prostate Cancer 87 114 .
Emma Nilsson & Charlotte Ling. (2017) DNA methylation links genetics, fetal environment, and an unhealthy lifestyle to the development of type 2 diabetes. Clinical Epigenetics 9:1.
Crossref
Priscila Sala, Raquel Susana Matos de Miranda Torrinhas, Danielle Cristina Fonseca, Graziela Rosa Ravacci, Dan Linetzky Waitzberg & Daniel Giannella-Neto. (2017) Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass. Diabetology & Metabolic Syndrome 9:1.
Crossref
David Lorite Mingot, Eva Gesteiro, Sara Bastida & Francisco J. Sánchez-Muniz. (2017) Epigenetic effects of the pregnancy Mediterranean diet adherence on the offspring metabolic syndrome markers. Journal of Physiology and Biochemistry 73:4, pages 495-510.
Crossref
Donato F. Romagnolo & Ornella I. Selmin. (2017) Mediterranean Diet and Prevention of Chronic Diseases. Nutrition Today 52:5, pages 208-222.
Crossref
Mohanraj Krishnan, Andrew N. Shelling, Clare R. Wall, Edwin A. Mitchell, Rinki Murphy, Lesley M.E. McCowan & John M.D. Thompson. (2017) Gene-by-environment interactions of the CLOCK, PEMT, and GHRELIN loci with average sleep duration in relation to obesity traits using a cohort of 643 New Zealand European children. Sleep Medicine 37, pages 19-26.
Crossref
Derek S. O’Neil, Christopher J. Stewart, Derrick M. Chu, Danielle M. Goodspeed, Pablo J. Gonzalez-Rodriguez, Cynthia D. Shope & Kjersti M. Aagaard. (2017) Conditional postnatal deletion of the neonatal murine hepatic circadian gene, Npas2, alters the gut microbiome following restricted feeding. American Journal of Obstetrics and Gynecology 217:2, pages 218.e1-218.e15.
Crossref
Abed E. Zubidat & Abraham Haim. (2017) Artificial light-at-night – a novel lifestyle risk factor for metabolic disorder and cancer morbidity. Journal of Basic and Clinical Physiology and Pharmacology 28:4, pages 295-313.
Crossref
Ana B Crujeiras, Angel Diaz-Lagares, Olafur A Stefansson, Manuel Macias-Gonzalez, Juan Sandoval, Juan Cueva, Rafael Lopez-Lopez, Sebastian Moran, Jon G Jonasson, Laufey Tryggvadottir, Elinborg Olafsdottir, Francisco J Tinahones, Marcos C Carreira, Felipe F Casanueva & Manel Esteller. (2017) Obesity and menopause modify the epigenomic profile of breast cancer. Endocrine-Related Cancer, pages 351-363.
Crossref
S. D. Poppitt. (2017) Obesity and Weight Control: Is There Light at the End of the Tunnel?. Current Nutrition Reports 6:2, pages 51-62.
Crossref
Lucia Aronica, A Joan Levine, Kevin Brennan, Jeffrey Mi, Christopher Gardner, Robert W Haile & Megan P Hitchins. (2017) A systematic review of studies of DNA methylation in the context of a weight loss intervention. Epigenomics 9:5, pages 769-787.
Crossref
Carla Bartosch, José Manuel Lopes & Carmen Jerónimo. (2017) Epigenetics in endometrial carcinogenesis – part 1: DNA methylation. Epigenomics 9:5, pages 737-755.
Crossref
Jae-Ho Park, Soon-Hee Kim, Myeong Soo Lee & Myung-Sunny Kim. (2017) Epigenetic modification by dietary factors: Implications in metabolic syndrome. Molecular Aspects of Medicine 54, pages 58-70.
Crossref
A. B. Crujeiras, A. Diaz-Lagares, J. Sandoval, F. I. Milagro, S. Navas-Carretero, M. C. Carreira, A. Gomez, D. Hervas, M. P. Monteiro, F. F. Casanueva, M. Esteller & J. A. Martinez. (2017) DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients. Scientific Reports 7:1.
Crossref
Xiaoli Su, Dan Chen, Kai Yang, Qin Zhao, Dan Zhao, Xiaoqiang Lv & Yiran Ao. (2017) The circadian clock gene PER2 plays an important role in tumor suppression through regulating tumor-associated genes in human oral squamous cell carcinoma. Oncology Reports 38:1, pages 472-480.
Crossref
Omar Ramos-Lopez, Fermín I. Milagro, Hooman Allayee, Agata Chmurzynska, Myung Sook Choi, Rui Curi, Raffaele De Caterina, Lynnette R. Ferguson, Leticia Goni, Jing X. Kang, Martin Kohlmeier, Amelia Marti, Luis A. Moreno, Louis Pérusse, Chandan Prasad, Lu Qi, Ram Reifen, Jose I. Riezu-Boj, Rodrigo San-Cristobal, Jose Luis Santos & J. Alfredo Martínez. (2017) Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity. Lifestyle Genomics 10:1-2, pages 43-62.
Crossref
Scott H. Deibel & Robert J. McDonald. 2017. Circadian Rhythms and Their Impact on Aging. Circadian Rhythms and Their Impact on Aging 269 304 .
Dolores Corella, Eva. M. Asensio, Oscar Coltell, José V. Sorlí, Ramón Estruch, Miguel Ángel Martínez-González, Jordi Salas-Salvadó, Olga Castañer, Fernando Arós, José Lapetra, Lluís Serra-Majem, Enrique Gómez-Gracia, Carolina Ortega-Azorín, Miquel Fiol, Javier Díez Espino, Andrés Díaz-López, Montserrat Fitó, Emilio Ros & José M. Ordovás. (2016) CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial. Cardiovascular Diabetology 15:1.
Crossref
Yigit Akin, Hakan Gulmez, Murat Savas, Serdar Aykan, Ozde Onder & Selcuk Yucel. (2015) Relationship between neck circumference and overactive bladder in women with metabolic syndrome: a preliminary study. Wiener klinische Wochenschrift 128:S8, pages 581-586.
Crossref
J. Lopez-Minguez, P. Gómez-Abellán & M. Garaulet. (2016) Circadian rhythms, food timing and obesity. Proceedings of the Nutrition Society 75:4, pages 501-511.
Crossref
Ariadna Amador, Salvador Huitron-Resendiz, Amanda J. Roberts, Theodore M. Kamenecka, Laura A. Solt & Thomas P. Burris. (2016) Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation. PLOS ONE 11:9, pages e0162452.
Crossref
Paola Casanello, Bernardo J. Krause, José A. Castro-Rodríguez & Ricardo Uauy. (2016) Epigenética y obesidad. Revista Chilena de Pediatría 87:5, pages 335-342.
Crossref
Mirian Samblas, Fermin I. Milagro, Purificación Gómez-Abellán, J. Alfredo Martínez & Marta Garaulet. (2016) Methylation on the Circadian Gene BMAL1 Is Associated with the Effects of a Weight Loss Intervention on Serum Lipid Levels . Journal of Biological Rhythms 31:3, pages 308-317.
Crossref
Yingmei Zhang & Jun Ren. (2016) Epigenetics and obesity cardiomyopathy: From pathophysiology to prevention and management. Pharmacology & Therapeutics 161, pages 52-66.
Crossref
Leticia Goni, Marta Cuervo, Fermín I Milagro & J Alfredo Martínez. (2016) Future Perspectives of Personalized Weight Loss Interventions Based on Nutrigenetic, Epigenetic, and Metagenomic Data. The Journal of Nutrition 146:4, pages 905S-912S.
Crossref
Lucía Fernández del Río, Elena Gutiérrez-Casado, Alfonso Varela-López & José Villalba. (2016) Olive Oil and the Hallmarks of Aging. Molecules 21:2, pages 163.
Crossref
Stephen W. Scherer & Peter M. VisscherYiyi Ma, Caren E. Smith, Yu-Chi Lee, Laurence D. Parnell, Chao-Qiang Lai & José M. Ordovás. 2015. Genome-Wide Association Studies. Genome-Wide Association Studies 193 207 .
Júlia Cristina Cardoso Carraro, Helen Hermana Miranda Hermsdorff, Maria Luisa Mansego, Maria Ángeles Zulet, Fermín I. Milagro, Josefina Bressan & J. Alfredo Martínez. (2016) Higher Fruit Intake Is Related to <b><i>TNF-α</i></b> Hypomethylation and Better Glucose Tolerance in Healthy Subjects. Lifestyle Genomics 9:2-4, pages 95-105.
Crossref
A. Lopomo, E. Burgio & L. Migliore. 2016. Genetics of Monogenic and Syndromic Obesity. Genetics of Monogenic and Syndromic Obesity 151 184 .
Ana B. Crujeiras & Angel Diaz-Lagares. 2016. Epigenetic Biomarkers and Diagnostics. Epigenetic Biomarkers and Diagnostics 313 329 .
Enrique J. Busó & Marisa Iborra. 2016. Epigenetic Biomarkers and Diagnostics. Epigenetic Biomarkers and Diagnostics 137 153 .
Michel Neidhart. 2016. DNA Methylation and Complex Human Disease. DNA Methylation and Complex Human Disease 201 214 .
Ruifang Li & Paul A. Wade. 2016. Epigenetics, Energy Balance, and Cancer. Epigenetics, Energy Balance, and Cancer 211 233 .
Sharon A. Ross. 2016. Mediterranean Diet. Mediterranean Diet 203 216 .
Pieterjan Dierickx, Bastiaan Du Pré, Dries A. M. Feyen, Niels Geijsen, Toon van Veen, Pieter A. Doevendans & Linda W. Van Laake. 2016. Stem Cells and Cardiac Regeneration. Stem Cells and Cardiac Regeneration 57 78 .
Andrée-Anne Houde, Cécilia Légaré, Simon Biron, Odette Lescelleur, Laurent Biertho, Simon Marceau, André Tchernof, Marie-Claude Vohl, Marie-France Hivert & Luigi Bouchard. (2015) Leptin and adiponectin DNA methylation levels in adipose tissues and blood cells are associated with BMI, waist girth and LDL-cholesterol levels in severely obese men and women. BMC Medical Genetics 16:1.
Crossref
F. I. Milagro, J. I. Riezu-Boj & J. A. Martinez. (2015) Epigenetic Determinants of Weight Management: Methylation Signatures. Current Nutrition Reports 4:4, pages 330-339.
Crossref
Scott H. Deibel, Erin L. Zelinski, Robin J. Keeley, Olga Kovalchuk & Robert J. McDonald. (2015) Epigenetic alterations in the suprachiasmatic nucleus and hippocampus contribute to age-related cognitive decline. Oncotarget 6:27, pages 23181-23203.
Crossref
Jonathan Cedernaes, Megan E. Osler, Sarah Voisin, Jan-Erik Broman, Heike Vogel, Suzanne L. Dickson, Juleen R. Zierath, Helgi B. Schiöth & Christian Benedict. (2015) Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men. The Journal of Clinical Endocrinology & Metabolism 100:9, pages E1255-E1261.
Crossref
A Mouralidarane, J Soeda, D Sugden, A Bocianowska, R Carter, S Ray, R Saraswati, P Cordero, M Novelli, G Fusai, M Vinciguerra, L Poston, P D Taylor & J A Oben. (2015) Maternal obesity programs offspring non-alcoholic fatty liver disease through disruption of 24-h rhythms in mice. International Journal of Obesity 39:9, pages 1339-1348.
Crossref
Yaarit Adamovich, Rona Aviram & Gad Asher. (2015) The emerging roles of lipids in circadian control. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1851:8, pages 1017-1025.
Crossref
Yeon Kyung Na, Hae Sook Hong, Won Kee Lee, Young Hun Kim & Dong Sun Kim. (2015) Increased Methylation of Interleukin 6 Gene Is Associated with Obesity in Korean Women. Molecules and Cells 38:5, pages 452-456.
Crossref
Sarah Voisin, Markus S Almén, George Moschonis, George P Chrousos, Yannis Manios & Helgi B Schiöth. (2014) Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents. European Journal of Human Genetics 23:5, pages 654-662.
Crossref
J. G. Lumaban & D. L. Nelson. (2014) The Fragile X proteins Fmrp and Fxr2p cooperate to regulate glucose metabolism in mice. Human Molecular Genetics 24:8, pages 2175-2184.
Crossref
Ernesto Burgio, Angela Lopomo & Lucia Migliore. (2014) Obesity and diabetes: from genetics to epigenetics. Molecular Biology Reports 42:4, pages 799-818.
Crossref
Ana B. Crujeiras & Felipe F. Casanueva. (2015) Obesity and the reproductive system disorders: epigenetics as a potential bridge. Human Reproduction Update 21:2, pages 249-261.
Crossref
Jessica M. Ferrell & John Y.L. Chiang. (2015) Circadian rhythms in liver metabolism and disease. Acta Pharmaceutica Sinica B 5:2, pages 113-122.
Crossref
S J van Dijk, P L Molloy, H Varinli, J L Morrison, B S Muhlhausler, M Buckley, S J Clark, I C McMillen, M Noakes, K Samaras & R L Tellam. (2014) Epigenetics and human obesity. International Journal of Obesity 39:1, pages 85-97.
Crossref
Anders M. Lindroth, Joo H. Park, Yeongran Yoo & Yoon J. Park. 2015. Personalized Epigenetics. Personalized Epigenetics 313 347 .
Marta Garaulet. 2015. The Mediterranean Diet. The Mediterranean Diet 237 247 .
Alena Stančáková & Markku Laakso. (2014) Genetics of metabolic syndrome. Reviews in Endocrine and Metabolic Disorders 15:4, pages 243-252.
Crossref
LITING ZHU, JUN YU, WENYI ZHANG, BIN XIE & YI ZHU. (2014) Research progress on the central mechanism underlying regulation of visceral biological rhythm by per2 (Review). Molecular Medicine Reports 10:5, pages 2241-2248.
Crossref
Leticia Goni, Fermín I Milagro, Marta Cuervo & J Alfredo Martínez. (2014) Single-nucleotide polymorphisms and DNA methylation markers associated with central obesity and regulation of body weight. Nutrition Reviews 72:11, pages 673-690.
Crossref
Y. Akin, H. Gulmez, A. Bozkurt, B. Nuhoglu & M. F. Usta. (2014) Usage of neck circumference as novel indicator of erectile dysfunction: a pilot study in Turkish population. Andrologia 46:9, pages 963-970.
Crossref
Qinqin Gao, Jiaqi Tang, Jie Chen, Lin Jiang, Xiaolin Zhu & Zhice Xu. (2014) Epigenetic code and potential epigenetic-based therapies against chronic diseases in developmental origins. Drug Discovery Today 19:11, pages 1744-1750.
Crossref
Liu Qing-Xiu, Huang Chang-Quan, Chen Qian, Zhang Xue-Mei, Hu Xiu-Ying & Li Song-Bing. (2014) The polymorphism of ARNTL2 (BMAL2) gene rs2306074 C>T is associated with susceptibility of Alzheimer disease in Chinese population. Neurological Sciences 35:11, pages 1743-1747.
Crossref
Hideaki Oike, Katsutaka Oishi & Masuko Kobori. (2014) Nutrients, Clock Genes, and Chrononutrition. Current Nutrition Reports 3:3, pages 204-212.
Crossref
Laura K. Fonken & Randy J. Nelson. (2014) The Effects of Light at Night on Circadian Clocks and Metabolism. Endocrine Reviews 35:4, pages 648-670.
Crossref
Yeon Kyung Na, Hae Sook Hong, Duk Hee Lee, Won Kee Lee & Dong Sun Kim. (2014) Effect of Body Mass Index on Global DNA Methylation in Healthy Korean Women. Molecules and Cells 37:6, pages 467-472.
Crossref
Gemma López-Guimerà, Hassan S. Dashti, Caren E. Smith, David Sánchez-Carracedo, Jose M. Ordovas & Marta Garaulet. (2014) CLOCK 3111 T/C SNP Interacts with Emotional Eating Behavior for Weight-Loss in a Mediterranean Population. PLoS ONE 9:6, pages e99152.
Crossref
Abdelhalim Azzi, Robert Dallmann, Alison Casserly, Hubert Rehrauer, Andrea Patrignani, Bert Maier, Achim Kramer & Steven A Brown. (2014) Circadian behavior is light-reprogrammed by plastic DNA methylation. Nature Neuroscience 17:3, pages 377-382.
Crossref
Irfan A. Qureshi & Mark F. Mehler. (2014) Epigenetics of Sleep and Chronobiology. Current Neurology and Neuroscience Reports 14:3.
Crossref
Keisuke Mori, Norio Iijima, Shimpei Higo, Satoko Aikawa, Izumi Matsuo, Ken Takumi, Atsuhiro Sakamoto & Hitoshi Ozawa. (2014) Epigenetic Suppression of Mouse Per2 Expression in the Suprachiasmatic Nucleus by the Inhalational Anesthetic, Sevoflurane. PLoS ONE 9:1, pages e87319.
Crossref
J. Alfredo Martínez, Fermín I. Milagro, Kate J. Claycombe & Kevin L. Schalinske. (2014) Epigenetics in Adipose Tissue, Obesity, Weight Loss, and Diabetes. Advances in Nutrition 5:1, pages 71-81.
Crossref
Cátia Lira do Amaral, Fermín I. Milagro, Rui Curi & J. Alfredo Martínez. (2014) DNA Methylation Pattern in Overweight Women under an Energy-Restricted Diet Supplemented with Fish Oil. BioMed Research International 2014, pages 1-10.
Crossref
Fátima Pérez de Heredia & Marta Garaulet. 2014. Nutrition in the Prevention and Treatment of Abdominal Obesity. Nutrition in the Prevention and Treatment of Abdominal Obesity 489 502 .
David Albuquerque, Licínio Manco & Clévio Nóbrega. 2014. Molecular Mechanisms Underpinning the Development of Obesity. Molecular Mechanisms Underpinning the Development of Obesity 101 127 .
Irfan A. Qureshi & Mark F. Mehler. 2013. The Genetic Basis of Sleep and Sleep Disorders. The Genetic Basis of Sleep and Sleep Disorders 127 138 .
. 2013. The Genetic Basis of Sleep and Sleep Disorders. The Genetic Basis of Sleep and Sleep Disorders 33 138 .
R. Satou, N. Sugihara, Y. Ishizuka, T. Matsukubo & Y. Onishi. (2013) DNA methylation of the BMAL1 promoter. Biochemical and Biophysical Research Communications 440:3, pages 449-453.
Crossref
Melanie A. Carless, Hemant Kulkarni, Mark Z. Kos, Jac Charlesworth, Juan M. Peralta, Harald H. H. Göring, Joanne E. Curran, Laura Almasy, Thomas D. Dyer, Anthony G. Comuzzie, Michael C. Mahaney & John Blangero. (2013) Genetic Effects on DNA Methylation and Its Potential Relevance for Obesity in Mexican Americans. PLoS ONE 8:9, pages e73950.
Crossref
Javier Labad & Rebecca M. Reynolds. (2013) Leptin, Somatic Depressive Symptoms and the Metabolic Syndrome: a Comment on Chirinos et al.. Annals of Behavioral Medicine 46:1, pages 5-6.
Crossref
S-Y Ju & W-S Choi. (2013) Sleep duration and metabolic syndrome in adult populations: a meta-analysis of observational studies. Nutrition & Diabetes 3:5, pages e65-e65.
Crossref
A. Moleres, J. A. Martinez & A. Marti. (2012) Genetics of Obesity. Current Obesity Reports 2:1, pages 23-31.
Crossref
Loning Fu & Nicole M. Kettner. 2013. Chronobiology: Biological Timing in Health and Disease. Chronobiology: Biological Timing in Health and Disease 221 282 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.