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Annals of Medicine Volume 42, 2010 - Issue 6
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MINI REVIEW

Genetic variants in MTNR1B affecting insulin secretion

Karsten Müssig Division of Endocrinology, Diabetology, Angiology, Nephrology, and Clinical Chemistry, Department of Internal Medicine, Eberhard Karls University, Member of the German Centre for Diabetes Research (DZD), Otfried-Müller-Str. 10, 72076 Tübingen, Germany
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Harald Staiger Division of Endocrinology, Diabetology, Angiology, Nephrology, and Clinical Chemistry, Department of Internal Medicine, Eberhard Karls University, Member of the German Centre for Diabetes Research (DZD), Otfried-Müller-Str. 10, 72076 Tübingen, Germany
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Fausto Machicao Division of Endocrinology, Diabetology, Angiology, Nephrology, and Clinical Chemistry, Department of Internal Medicine, Eberhard Karls University, Member of the German Centre for Diabetes Research (DZD), Otfried-Müller-Str. 10, 72076 Tübingen, Germany
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Hans-Ulrich Häring Division of Endocrinology, Diabetology, Angiology, Nephrology, and Clinical Chemistry, Department of Internal Medicine, Eberhard Karls University, Member of the German Centre for Diabetes Research (DZD), Otfried-Müller-Str. 10, 72076 Tübingen, GermanyCorrespondence[email protected]
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Andreas Fritsche Division of Endocrinology, Diabetology, Angiology, Nephrology, and Clinical Chemistry, Department of Internal Medicine, Eberhard Karls University, Member of the German Centre for Diabetes Research (DZD), Otfried-Müller-Str. 10, 72076 Tübingen, Germany
Pages 387-393 | Received 22 Mar 2010, Accepted 10 Jun 2010, Published online: 02 Jul 2010

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Kadri Haljas, Jari Lahti, Tiinamaija Tuomi, Bo Isomaa, Johan G. Eriksson, Leif Groop & Katri Räikkönen. (2018) Melatonin receptor 1B gene rs10830963 polymorphism, depressive symptoms and glycaemic traits. Annals of Medicine 50:8, pages 704-712.
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Gianluigi Mazzoccoli, Mariangela Pia Dagostino, Giulia Paroni, Davide Seripa, Filomena Ciccone, Filomena Addante, Giovanni Favuzzi, Elvira Grandone, Roberto Avola, Tommaso Mazza, Caterina Fusilli, Antonio Greco & Salvatore De Cosmo. (2017) Analysis of MTNR1B gene polymorphisms in relationship with IRS2 gene variants, epicardial fat thickness, glucose homeostasis and cognitive performance in the elderly. Chronobiology International 34:8, pages 1083-1093.
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Doron Garfinkel, Mariana Zorin, Julio Wainstein, Zipora Matas, Moshe Laudon & Nava Zisapel. (2011) Efficacy and safety of prolonged-release melatonin in insomnia patients with diabetes: a randomized, double-blind, crossover study. Diabetes, Metabolic Syndrome and Obesity 4, pages 307-313.
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Yi Zhang, Kai Zhao, Lei Jin, Yuanzhong Zhou, Xuejun Shang, Xin Wang & Hongsong Yu. (2024) MTNR1B gene variations and high pre-pregnancy BMI increase gestational diabetes mellitus risk in Chinese women. Gene 894, pages 148023.
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Katayoun Heshmatzad, Niloofar Naderi, Majid Maleki, Shiva Abbasi, Serwa Ghasemi, Nooshin Ashrafi, Amir Farjam Fazelifar, Mohammad Mahdavi & Samira Kalayinia. (2023) Role of non‐coding variants in cardiovascular disease. Journal of Cellular and Molecular Medicine 27:12, pages 1621-1636.
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Jian-Yan Lin & Rui-Xing Yin. (2022) Exposure to Endocrine-Disrupting Chemicals and Type 2 Diabetes Mellitus in Later Life. Exposure and Health 15:1, pages 199-229.
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Taylor W. Cook, Amy M. Wilstermann, Jackson T. Mitchell, Nicholas E. Arnold, Surender Rajasekaran, Caleb P. Bupp & Jeremy W. Prokop. (2023) Understanding Insulin in the Age of Precision Medicine and Big Data: Under-Explored Nature of Genomics. Biomolecules 13:2, pages 257.
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Asif Jan, Zakiullah, Sajid Ali, Basir Muhammad, Amina Arshad, Yasar Shah, Haji Bahadur, Hamayun Khan, Fazli Khuda, Rani Akbar & Kiran Ijaz. (2023) Decoding type 2 diabetes mellitus genetic risk variants in Pakistani Pashtun ethnic population using the nascent whole exome sequencing and MassARRAY genotyping: A case-control association study. PLOS ONE 18:1, pages e0281070.
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Marta Garaulet, Jesus Lopez-Minguez, Hassan S. Dashti, Céline Vetter, Antonio Miguel Hernández-Martínez, Millán Pérez-Ayala, Juan Carlos Baraza, Wei Wang, Jose C. Florez, Frank A.J.L. Scheer & Richa Saxena. (2022) Interplay of Dinner Timing and MTNR1B Type 2 Diabetes Risk Variant on Glucose Tolerance and Insulin Secretion: A Randomized Crossover Trial . Diabetes Care 45:3, pages 512-519.
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Mireille NM van Poppel, Rosa Corcoy, David Hill, David Simmons, Leire Mendizabal, Mirella Zulueta, Laureano Simon & Gernot Desoye. (2022) Interaction between rs10830962 polymorphism in MTNR1B and lifestyle intervention on maternal and neonatal outcomes: secondary analyses of the DALI lifestyle randomized controlled trial. The American Journal of Clinical Nutrition 115:2, pages 388-396.
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Karsten Müssig. (2022) Wer gut schläft, fördert seine Stoffwechselgesundheit. Info Diabetologie 16:1, pages 22-23.
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Georgi Nikolaev, Ralitsa Robeva & Rossitza Konakchieva. (2021) Membrane Melatonin Receptors Activated Cell Signaling in Physiology and Disease. International Journal of Molecular Sciences 23:1, pages 471.
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Frank M. C. Besag, Michael J. Vasey, Kim S. J. Lao & Ian C. K. Wong. (2019) Adverse Events Associated with Melatonin for the Treatment of Primary or Secondary Sleep Disorders: A Systematic Review. CNS Drugs 33:12, pages 1167-1186.
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Juan C. Mayo, Arturo Aguado, Rafael Cernuda-Cernuda, Alejandro Álvarez-Artime, Vanesa Cepas, Isabel Quirós-González, David Hevia & Rosa M. Sáinz. (2018) Melatonin Uptake by Cells: An Answer to Its Relationship with Glucose?. Molecules 23:8, pages 1999.
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Nilgün Çöl, Muradiye Nacak & Mustafa Araz. (2018) Association of melatonin receptor 1 B gene (rs10830963 and rs9192552) polymorphısm with adolescent obesity and related comorbidities in Turkey . Journal of International Medical Research 46:8, pages 3086-3096.
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Adejoke Y Onaolapo & Olakunle J Onaolapo. (2018) Circadian dysrhythmia-linked diabetes mellitus: Examining melatonin’s roles in prophylaxis and management. World Journal of Diabetes 9:7, pages 99-114.
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Ikenna Eze, Medea Imboden, Maria Foraster, Emmanuel Schaffner, Ashish Kumar, Danielle Vienneau, Harris Héritier, Franziska Rudzik, Laurie Thiesse, Reto Pieren, Arnold von Eckardstein, Christian Schindler, Mark Brink, Jean-Marc Wunderli, Christian Cajochen, Martin Röösli & Nicole Probst-Hensch. (2017) Exposure to Night-Time Traffic Noise, Melatonin-Regulating Gene Variants and Change in Glycemia in Adults. International Journal of Environmental Research and Public Health 14:12, pages 1492.
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Ken Declerck, Sylvie Remy, Christine Wohlfahrt-Veje, Katharina M. Main, Guy Van Camp, Greet Schoeters, Wim Vanden Berghe & Helle R. Andersen. (2017) Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk—an exploratory study. Clinical Epigenetics 9:1.
Crossref
Mengrong Cheng, Xinhong Liu, Mei Yang, Lanchun Han, Aimin Xu & Qingyang Huang. (2016) Computational analyses of type 2 diabetes‐associated loci identified by genome‐wide association studies. Journal of Diabetes 9:4, pages 362-377.
Crossref
Maria A. Matuszek, Angelyn Anton, Sobana Thillainathan & Nicola J. Armstrong. (2015) Increased Insulin following an Oral Glucose Load, Genetic Variation near the Melatonin Receptor MTNR1B, but No Biochemical Evidence of Endothelial Dysfunction in Young Asian Men and Women. PLOS ONE 10:7, pages e0133611.
Crossref
Frida Renström, Robert W. Koivula, Tibor V. Varga, Göran Hallmans, Hindrik Mulder, Jose C. Florez, Frank B. Hu & Paul W. Franks. (2015) Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: the GLACIER Study. Diabetologia 58:5, pages 997-1005.
Crossref
Moshe Laudon & Anat Frydman-Marom. (2014) Therapeutic Effects of Melatonin Receptor Agonists on Sleep and Comorbid Disorders. International Journal of Molecular Sciences 15:9, pages 15924-15950.
Crossref
Rashmi Chandra & Rodger A. Liddle. (2012) Neurohormonal regulation of pancreatic secretion. Current Opinion in Gastroenterology 28:5, pages 483-487.
Crossref
É B Arushanian. (2012) Melatonin and diabetes mellitus (an overview of current experimental data). Problems of Endocrinology 58:3, pages 35-40.
Crossref
Sandra L. Deming, Wei Lu, Alicia Beeghly-Fadiel, Ying Zheng, Qiuyin Cai, Jirong Long, Xiao Ou Shu, Yu-Tang Gao & Wei Zheng. (2011) Melatonin pathway genes and breast cancer risk among Chinese women. Breast Cancer Research and Treatment 132:2, pages 693-699.
Crossref
Rüdiger Hardeland, Juan Antonio Madrid, Dun‐Xian Tan & Russel J. Reiter. (2011) Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling. Journal of Pineal Research 52:2, pages 139-166.
Crossref
David J. Kennaway, Julie A. Owens, Athena Voultsios & Nicole Wight. (2012) Adipokines and Adipocyte Function in Clock Mutant Mice That Retain Melatonin Rhythmicity . Obesity 20:2, pages 295-305.
Crossref
Rüdiger Hardeland. (2012) Neurobiology, Pathophysiology, and Treatment of Melatonin Deficiency and Dysfunction. The Scientific World Journal 2012, pages 1-18.
Crossref

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