1,871
Views
114
CrossRef citations to date
0
Altmetric
Review Article

Vascular aging: Chronic oxidative stress and impairment of redox signaling—consequences for vascular homeostasis and disease

, , , , , , & show all
Pages 17-36 | Received 13 Jul 2011, Accepted 13 Oct 2011, Published online: 01 Mar 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Rayan Khaddaj Mallat, Cini Mathew John, Dylan J. Kendrick & Andrew P. Braun. (2017) The vascular endothelium: A regulator of arterial tone and interface for the immune system. Critical Reviews in Clinical Laboratory Sciences 54:7-8, pages 458-470.
Read now
J. Konradi, M. Mollenhauer, S. Baldus & A. Klinke. (2015) Redox-sensitive mechanisms underlying vascular dysfunction in heart failure. Free Radical Research 49:6, pages 721-742.
Read now

Articles from other publishers (112)

Mohamed Kodiha, Nabila Azad, Siwei Chu, Noah Crampton & Ursula Stochaj. (2024) Oxidative stress and signaling through EGFR and PKA pathways converge on the nuclear transport factor RanBP1. European Journal of Cell Biology 103:1, pages 151376.
Crossref
Zachary S. Clayton, Matthew J. Rossman, Sophia A. Mahoney, Ravinandan VenkatasubramanianGrace S. MaurerDavid A. Hutton, Nicholas S. VanDongenNathan T. GreenbergAbigail G. Longtine, Katelyn R. LudwigVienna E. Brunt, Thomas J. LaRoccaJudith Campisi, Simon Melov & Douglas R. Seals. (2023) Cellular Senescence Contributes to Large Elastic Artery Stiffening and Endothelial Dysfunction With Aging: Amelioration With Senolytic Treatment. Hypertension 80:10, pages 2072-2087.
Crossref
Jeanette A. Maier, Vicente Andrés, Sara Castiglioni, Alessandro Giudici, Emily S. Lau, János Nemcsik, Francesca Seta, Paola Zaninotto, Mariella Catalano & Naomi M. Hamburg. (2023) Aging and Vascular Disease: A Multidisciplinary Overview. Journal of Clinical Medicine 12:17, pages 5512.
Crossref
Emily K. Woolf, Janée D. Terwoord, Nicole S. Litwin, Allegra R. Vazquez, Sylvia Y. Lee, Nancy Ghanem, Kiri A. Michell, Brayden T. Smith, Lauren E. Grabos, Nathaniel B. Ketelhut, Nate P. Bachman, Meghan E. Smith, Melanie Le Sayec, Sangeeta Rao, Christopher L. Gentile, Tiffany L. Weir, Ana Rodriguez-Mateos, Douglas R. Seals, Frank A. Dinenno & Sarah A. Johnson. (2023) Daily blueberry consumption for 12 weeks improves endothelial function in postmenopausal women with above-normal blood pressure through reductions in oxidative stress: a randomized controlled trial. Food & Function 14:6, pages 2621-2641.
Crossref
Oh Sung Kwon, Sung Gi Noh, Soung Hun Park, Robert H. I. Andtbacka, John R. Hyngstrom & Russell S. Richardson. (2022) Ageing and endothelium‐mediated vascular dysfunction: the role of the NADPH oxidases. The Journal of Physiology 601:3, pages 451-467.
Crossref
Tessa Helman & Nady Braidy. (2022) Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders. Drugs & Aging 40:1, pages 33-48.
Crossref
Francesco Nappi, Antonio Fiore, Joyce Masiglat, Teresa Cavuoti, Michela Romandini, Pierluigi Nappi, Sanjeet Singh Avtaar Singh & Jean-Paul Couetil. (2022) Endothelium-Derived Relaxing Factors and Endothelial Function: A Systematic Review. Biomedicines 10:11, pages 2884.
Crossref
Abigail G. Casso, Nicholas S. VanDongen, Rachel A. Gioscia‐Ryan, Zachary S. Clayton, Nathan T. Greenberg, Brian P. Ziemba, David A. Hutton, Andrew P. Neilson, Kevin P. Davy, Douglas R. Seals & Vienna E. Brunt. (2022) Initiation of 3,3‐dimethyl‐1‐butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in mice . The Journal of Physiology 600:21, pages 4633-4651.
Crossref
Oliver M. Shannon, Tom Clifford, Douglas R. Seals, Daniel H. Craighead & Matthew J. Rossman. (2022) Nitric oxide, aging and aerobic exercise: Sedentary individuals to Master's athletes. Nitric Oxide 125-126, pages 31-39.
Crossref
Hui Xu, Shuang Li & You-Shuo Liu. (2022) Nanoparticles in the diagnosis and treatment of vascular aging and related diseases. Signal Transduction and Targeted Therapy 7:1.
Crossref
D. Couchie, T. Medali, V. Diderot, M. Raymondjean, B. Friguet & M. Rouis. (2022) Circadian rhythmicity of the thioredoxin system in cultured murine peritoneal macrophages. Biochimie 198, pages 76-85.
Crossref
Shadi Mahbubfam, Jafar Rezaie & Vahid Nejati. (2022) Crosstalk between exosomes signaling pathway and autophagy flux in senescent human endothelial cells. Tissue and Cell 76, pages 101803.
Crossref
Dominga Iacobazzi, Valeria Vincenza Alvino, Massimo Caputo & Paolo Madeddu. (2022) Accelerated Cardiac Aging in Patients With Congenital Heart Disease. Frontiers in Cardiovascular Medicine 9.
Crossref
Yue Qiu, Chun-yan Chao, Li Jiang, Jie Zhang, Qian-qian Niu, Ya-qi Guo, Yu-ting Song, Peng Li, Mo-li Zhu & Ya-ling Yin. (2022) Citronellal alleviate macro- and micro-vascular damage in high fat diet / streptozotocin - Induced diabetic rats via a S1P/S1P1 dependent signaling pathway. European Journal of Pharmacology 920, pages 174796.
Crossref
Biplab K. Maiti, Luisa B. Maia & José J.G. Moura. (2022) Sulfide and transition metals - A partnership for life. Journal of Inorganic Biochemistry 227, pages 111687.
Crossref
Samsul Arefin, Agne Laucyte-Cibulskiene, Sam Hobson, Angelina Schwarz, Lu Dai, Karolina Kublickiene & Peter Stenvinkel. 2022. Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease. Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease 391 405 .
Fraser SmithFraser Smith. 2022. Naturopathic Medicine. Naturopathic Medicine 225 413 .
Denise Eckert, Felicitas Rapp, Ayele T. Tsedeke, Jessica Molendowska, Robert Lehn, Markus Langhans, Claudia Fournier, Franz Rödel & Stephanie Hehlgans. (2021) ROS- and Radiation Source-Dependent Modulation of Leukocyte Adhesion to Primary Microvascular Endothelial Cells. Cells 11:1, pages 72.
Crossref
Andrew V. Kuczmarski, Laura M. Welti, Kerrie L. Moreau & Megan M. Wenner. (2021) ET-1 as a Sex-Specific Mechanism Impacting Age-Related Changes in Vascular Function. Frontiers in Aging 2.
Crossref
Asato Otsubo, Minoru Miyazato, Takuma Oshiro, Ryu Kimura, Tomohiro Matsuo, Yasuyoshi Miyata & Hideki Sakai. (2021) Age-associated bladder and urethral coordination impairment and changes in urethral oxidative stress in rats. Life Sciences 279, pages 119690.
Crossref
Rakesh Kumar Chandan, Prem Nath Suman & Keshav Sinha. 2021. Handbook of Research on Knowledge and Organization Systems in Library and Information Science. Handbook of Research on Knowledge and Organization Systems in Library and Information Science 48 68 .
Vienna E. Brunt & Christopher T. Minson. (2021) Heat therapy: mechanistic underpinnings and applications to cardiovascular health. Journal of Applied Physiology 130:6, pages 1684-1704.
Crossref
Takuma Oshiro, Ryu Kimura, Keiichiro Izumi, Asuka Ashikari, Seiichi Saito & Minoru Miyazato. (2020) Changes in urethral smooth muscle and external urethral sphincter function with age in rats. Physiological Reports 8:24.
Crossref
Alireza R. Rezaie & Hemant Giri. (2020) Anticoagulant and signaling functions of antithrombin. Journal of Thrombosis and Haemostasis 18:12, pages 3142-3153.
Crossref
Sai Dheeraj Gutlapalli, Varshitha Kondapaneni, Ijeoma A Toulassi, Sujan Poudel, Mehwish Zeb, Jinal Choudhari & Ivan Cancarevic. (2020) The Effects of Resveratrol on Telomeres and Post Myocardial Infarction Remodeling. Cureus.
Crossref
Gi Dae Kim & Seonghee Park. (2020) Effects of Cudrania tricuspidata on anti‐senescence in high glucose‐treated endothelial cells via the Akt/p53/p21 pathway . Food Science & Nutrition 8:11, pages 5999-6006.
Crossref
Lara Testai, Valentina Citi, Alma Martelli, Simone Brogi & Vincenzo Calderone. (2020) Role of hydrogen sulfide in cardiovascular ageing. Pharmacological Research 160, pages 105125.
Crossref
Philip C. Calder. (2020) Eicosanoids. Essays in Biochemistry 64:3, pages 423-441.
Crossref
Vienna E. BruntRachel A. Gioscia-RyanAbigail G. CassoNicholas S. VanDongenBrian P. ZiembaZachary J. SapinsleyJames J. RicheyMelanie C. ZiglerAndrew P. NeilsonKevin P. DavyDouglas R. Seals. (2020) Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans. Hypertension 76:1, pages 101-112.
Crossref
Evan Tracy, Gabrielle Rowe & Amanda J. LeBlanc. (2020) Cardiac tissue remodeling in healthy aging: the road to pathology. American Journal of Physiology-Cell Physiology 319:1, pages C166-C182.
Crossref
Haili Wang, Xiaojia Tang, Hongyang Fan, Yuhan Luo, Yuxia Song, Yao Xu & Yingzhu Chen. (2020) Potential mechanisms of hemorrhagic stroke in elderly COVID-19 patients. Aging 12:11, pages 10022-10034.
Crossref
Samsul Arefin, Sarah Buchanan, Sam Hobson, Julia Steinmetz, Shno Alsalhi, Paul G. Shiels, Karolina Kublickiene & Peter Stenvinkel. (2020) Nrf2 in early vascular ageing: Calcification, senescence and therapy. Clinica Chimica Acta 505, pages 108-118.
Crossref
Rafid Inam, Jason Gandhi, Gunjan Joshi, Varun Talanki, Noel L. Smith & Sardar Ali Khan. (2020) Current Understanding of Vascular Wall Pathophysiology in Erectile Dysfunction and Priapism. SN Comprehensive Clinical Medicine 2:6, pages 734-745.
Crossref
Weiqi Hong, Fei Mo, Ziqi Zhang, Mengyuan Huang & Xiawei Wei. (2020) Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism. Frontiers in Cell and Developmental Biology 8.
Crossref
Amin Karan, Elango Bhakkiyalakshmi, Ravichandran Jayasuriya, D.V.L. Sarada & Kunka Mohanram Ramkumar. (2020) The pivotal role of nuclear factor erythroid 2-related factor 2 in diabetes-induced endothelial dysfunction. Pharmacological Research 153, pages 104601.
Crossref
Pan Chang, Xiaomeng Zhang, Mingyang Zhang, Guohua Li, Lang Hu, Huishou Zhao, Xiaoxing Zhu, Juan Wu, Xihui Wang, Kaiyan Wang, Jing Zhang, Minggang Ren, Baoying Chen, Xiaoling Zhu, Miaozhang Zhu & Jun Yu. (2019) Swimming exercise inhibits myocardial ER stress in the hearts of aged mice by enhancing cGMP‑PKG signaling. Molecular Medicine Reports.
Crossref
Nathane Rosa Rodrigues, Jéssica Eduarda dos Santos Batista, Lorena Raspante de Souza, Illana Kemmerich Martins, Giulianna Echeverria Macedo, Litiele Cezar da Cruz, Dennis Guilherme da Costa Silva, Antonio Ivanildo Pinho, Henrique Douglas Melo Coutinho, Gabriel Luz Wallau, Thais Posser & Jeferson Luis Franco. (2019) Activation of p38MAPK and NRF2 signaling pathways in the toxicity induced by chlorpyrifos in Drosophila melanogaster: Protective effects of Psidium guajava pomífera L. (Myrtaceae) hydroalcoholic extract. Arabian Journal of Chemistry 12:8, pages 3490-3502.
Crossref
Roman A. Zinovkin & Andrey A. Zamyatnin. (2019) Mitochondria-Targeted Drugs. Current Molecular Pharmacology 12:3, pages 202-214.
Crossref
Lili Gu, Pei Ye, Hengli Li, Yue Wang, Yaqiong Xu, Qinghua Tian, Gaoxin Lei, Cheng Zhao, Zhan Gao, Wenfeng Zhao & Shuhua Tan. (2019) Lunasin attenuates oxidant‐induced endothelial injury and inhibits atherosclerotic plaque progression in ApoE −/− mice by up‐regulating heme oxygenase‐1 via PI3K/Akt/Nrf2/ARE pathway . The FASEB Journal 33:4, pages 4836-4850.
Crossref
Di Shao, Chunxiang Yao, Maya H. Kim, Jessica Fry, Richard A. Cohen, Catherine E. Costello, Reiko Matsui, Francesca Seta, Mark E. McComb & Markus M. Bachschmid. (2019) Improved mass spectrometry-based activity assay reveals oxidative and metabolic stress as sirtuin-1 regulators. Redox Biology 22, pages 101150.
Crossref
Ömer Özçağlayan, Murat Akgül, Cenk Yazıcı, Tuğba İlkem Özçağlayan, Arzu Malak & Mücahit Doğru MD. (2019) Is bladder blood flow an etiologic factor for the bladder pain syndrome?. Neurourology and Urodynamics 38:4, pages 1135-1141.
Crossref
Erik Behringer & Md Hakim. (2019) Functional Interaction among KCa and TRP Channels for Cardiovascular Physiology: Modern Perspectives on Aging and Chronic Disease. International Journal of Molecular Sciences 20:6, pages 1380.
Crossref
Han-wei Yang, Hui-ling Hong, Wen-wei Luo, Chun-mei Dai, Xin-yi Chen, Lu-ping Wang, Qian Li, Zi-qing Li, Pei-qing Liu & Zhuo-ming Li. (2018) mTORC2 facilitates endothelial cell senescence by suppressing Nrf2 expression via the Akt/GSK-3β/C/EBPα signaling pathway. Acta Pharmacologica Sinica 39:12, pages 1837-1846.
Crossref
Luisa B. Maia & José J.G. Moura. (2018) Putting xanthine oxidoreductase and aldehyde oxidase on the NO metabolism map: Nitrite reduction by molybdoenzymes. Redox Biology 19, pages 274-289.
Crossref
Karl Björling, Philomeena D. Joseph, Kristian Egebjerg, Max Salomonsson, Jakob L. Hansen, Trine P. Ludvigsen & Lars J. Jensen. (2018) Role of age, Rho-kinase 2 expression, and G protein-mediated signaling in the myogenic response in mouse small mesenteric arteries. Physiological Reports 6:17, pages e13863.
Crossref
Eva Latorre, Roberta Torregrossa, Mark E. Wood, Matthew Whiteman & Lorna W. Harries. (2018) Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2. Aging 10:7, pages 1666-1681.
Crossref
Agostino Di Ciaula. (2018) Towards 5G communication systems: Are there health implications?. International Journal of Hygiene and Environmental Health 221:3, pages 367-375.
Crossref
Xinrui Wang, Changlong Zhang, Yajie Peng, Haimin Zhang, Zhigang Wang, Yang Gao, Ying Liu & Hailong Zhang. (2018) Chemical constituents, antioxidant and gastrointestinal transit accelerating activities of dried fruit of Crataegus dahurica. Food Chemistry 246, pages 41-47.
Crossref
Urban Alehagen, Jan Aaseth, Jan Alexander, Erland Svensson, Peter Johansson & Anders Larsson. (2018) Less fibrosis in elderly subjects supplemented with selenium and coenzyme Q10-A mechanism behind reduced cardiovascular mortality?. BioFactors 44:2, pages 137-147.
Crossref
S.-Y. Park, O. S. Kwon, R. H. I. Andtbacka, J. R. Hyngstrom, V. Reese, M. P. Murphy & R. S. Richardson. (2018) Age-related endothelial dysfunction in human skeletal muscle feed arteries: the role of free radicals derived from mitochondria in the vasculature. Acta Physiologica 222:1, pages e12893.
Crossref
Luisa B. Maia & José J.G. Moura. 2018. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering.
Kumar K.J. Senthil, Vani M. Gokila & Sheng-Yang Wang. (2017) Activation of Nrf2-mediated anti-oxidant genes by antrodin C prevents hyperglycemia-induced senescence and apoptosis in human endothelial cells. Oncotarget 8:57, pages 96568-96587.
Crossref
Erik J. Behringer. (2017) Calcium and electrical signaling in arterial endothelial tubes: New insights into cellular physiology and cardiovascular function. Microcirculation 24:3.
Crossref
Bahareh Vahabi, Adrian S. Wagg, Peter F.W.M. Rosier, Kevin L.J. Rademakers, Marie-Astrid Denys, Michel Pontari, Thelma Lovick, Francoise A. Valentini, Pierre P. Nelson, Karl-Erik Andersson & Christopher H. Fry. (2017) Can we define and characterize the aging lower urinary tract?-ICI-RS 2015. Neurourology and Urodynamics 36:4, pages 854-858.
Crossref
Karl-Erik Andersson, Donna B. Boedtkjer & Axel Forman. (2016) The link between vascular dysfunction, bladder ischemia, and aging bladder dysfunction. Therapeutic Advances in Urology 9:1, pages 11-27.
Crossref
Ming Gu, Usmah Kawoos, Richard McCarron & Mikulas Chavko. (2017) Protection against Blast-Induced Traumatic Brain Injury by Increase in Brain Volume. BioMed Research International 2017, pages 1-10.
Crossref
Calogera Pisano, Carmela Rita Balistreri, Alessandro Ricasoli & Giovanni Ruvolo. (2017) Cardiovascular Disease in Ageing: An Overview on Thoracic Aortic Aneurysm as an Emerging Inflammatory Disease. Mediators of Inflammation 2017, pages 1-8.
Crossref
Lawrence C. Johnson, Allison E. DeVan, Jamie N. Justice & Douglas R. Seals. 2017. Nitrite and Nitrate in Human Health and Disease. Nitrite and Nitrate in Human Health and Disease 259 277 .
Rachel A. Gioscia-Ryan, Micah L. Battson, Lauren M. Cuevas, Melanie C. Zigler, Amy L. Sindler & Douglas R. Seals. (2016) Voluntary aerobic exercise increases arterial resilience and mitochondrial health with aging in mice. Aging 8:11, pages 2897-2914.
Crossref
A. PUZSEROVA & I. BERNATOVA. (2016) Blood Pressure Regulation in Stress: Focus on Nitric Oxide-Dependent Mechanisms. Physiological Research, pages S309-S342.
Crossref
I. BERNÁTOVÁ, P. BALIŠ, R. GOGA, M. BEHULIAK, J. ZICHA & I. SEKAJ. (2016) Lack of Reactive Oxygen Species Deteriorates Blood Pressure Regulation in Acute Stress. Physiological Research, pages S381-S390.
Crossref
Tengfei Zhou, Mengqian Zhang, Liang Zhao, Aiqin Li & Xiaomei Qin. (2016) Activation of Nrf2 contributes to the protective effect of Exendin-4 against angiotensin II-induced vascular smooth muscle cell senescence. American Journal of Physiology-Cell Physiology 311:4, pages C572-C582.
Crossref
Lasse Gliemann, Michael Nyberg & Ylva Hellsten. (2016) Effects of exercise training and resveratrol on vascular health in aging. Free Radical Biology and Medicine 98, pages 165-176.
Crossref
Alberto Sanz. (2016) Mitochondrial reactive oxygen species: Do they extend or shorten animal lifespan?. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1857:8, pages 1116-1126.
Crossref
César Hernández-Guerrero, Paulina Hernández-Chávez, Inés Romo-Palafox, Grecia Blanco-Melo, Alicia Parra-Carriedo & Ana Pérez-Lizaur. (2016) Genetic Polymorphisms in SOD (rs2070424, rs7880) and CAT (rs7943316, rs1001179) Enzymes Are Associated with Increased Body Fat Percentage and Visceral Fat in an Obese Population from Central Mexico. Archives of Medical Research 47:5, pages 331-339.
Crossref
Natalie E. Picciotto, Lindsey B. Gano, Lawrence C. Johnson, Christopher R. Martens, Amy L. Sindler, Kathryn F. Mills, Shin‐ichiro Imai & Douglas R. Seals. (2016) Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice. Aging Cell 15:3, pages 522-530.
Crossref
M. A. Hanson, C. Cooper, A. Aihie Sayer, R. J. Eendebak, G. F. Clough & J. R. Beard. (2016) Developmental aspects of a life course approach to healthy ageing. The Journal of Physiology 594:8, pages 2147-2160.
Crossref
Andrea T. Obi, Kathleen A. Stringer, Jose A. Diaz, Michael A. Finkel, Diana M. Farris, Larisa Yeomans, Thomas Wakefield & Daniel D. MyersJr.Jr.. (2016) 1D-1H-nuclear magnetic resonance metabolomics reveals age-related changes in metabolites associated with experimental venous thrombosis. Journal of Vascular Surgery: Venous and Lymphatic Disorders 4:2, pages 221-230.
Crossref
ES Nakou, FI Parthenakis, EM Kallergis, ME Marketou, KS Nakos & PE Vardas. (2016) Healthy aging and myocardium: A complicated process with various effects in cardiac structure and physiology. International Journal of Cardiology 209, pages 167-175.
Crossref
Jorge G. Farías, Emilio A. Herrera, Catalina Carrasco-Pozo, Ramón Sotomayor-Zárate, Gonzalo Cruz, Paola Morales & Rodrigo L. Castillo. (2016) Pharmacological models and approaches for pathophysiological conditions associated with hypoxia and oxidative stress. Pharmacology & Therapeutics 158, pages 1-23.
Crossref
Lucas F. Bianchini, Chris M. Wood, Harold L. Bergman, Ora E. Johannsson, Pierre Laurent, Claudine Chevalier, Mosiany L. Kisipan, Geraldine D. Kavembe, Michael B. Papah, Kevin V. Brix, Gudrun De Boeck, John N. Maina, Rodi O. Ojoo & Adalto Bianchini. (2016) Metabolism and antioxidant defense in the larval chironomid Tanytarsus minutipalpus : Adjustments to diel variations in the extreme conditions of Lake Magadi . Biology Open.
Crossref
Hye Eun Yoon, Eun Nim Kim, Min Young Kim, Ji Hee Lim, In-Ae Jang, Tae Hyun Ban, Seok Joon Shin, Cheol Whee Park, Yoon Sik Chang & Bum Soon Choi. (2016) Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice. Oxidative Medicine and Cellular Longevity 2016, pages 1-14.
Crossref
Verónica Guarner-Lans, Elizabeth Soria-Castro, Rocío Torrico-Lavayen, Araceli Patrón-Soberano, Karla G. Carvajal-Aguilera, Vicente Castrejón-Tellez & María Esther Rubio-Ruiz. (2016) Changes in Angiotensin Receptor Distribution and in Aortic Morphology Are Associated with Blood Pressure Control in Aged Metabolic Syndrome Rats. International Journal of Hypertension 2016, pages 1-11.
Crossref
Erik J. Behringer & Steven S. Segal. 2016. Vascular Ion Channels in Physiology and Disease. Vascular Ion Channels in Physiology and Disease 79 99 .
Hale Z Toklu, Judy Muller-Delp, Zhihui Yang, Şehkar Oktay, Yasemin Sakarya, Kevin Strang, Payal Ghosh, Michael D Delp, Philip J Scarpace, Kevin KW Wang & Nihal Tümer. (2015) The Functional and Structural Changes in the Basilar Artery Due to Overpressure Blast Injury. Journal of Cerebral Blood Flow & Metabolism 35:12, pages 1950-1956.
Crossref
Florenta Aura Kullmann, Lori Ann Birder & Karl-Erik Andersson. (2015) Translational Research and Functional Changes in Voiding Function in Older Adults. Clinics in Geriatric Medicine 31:4, pages 535-548.
Crossref
Bibi S. van Thiel, Ingrid van der Pluijm, Luuk te Riet, Jeroen Essers & A.H. Jan Danser. (2015) The renin–angiotensin system and its involvement in vascular disease. European Journal of Pharmacology 763, pages 3-14.
Crossref
Shiqin Xiong, Nikolay Patrushev, Farshad Forouzandeh, Lula Hilenski & R. Wayne Alexander. (2015) PGC-1α Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases. Cell Reports 12:9, pages 1391-1399.
Crossref
Bo Chen, Yanrong Lu, Younan Chen & Jingqiu Cheng. (2015) The role of Nrf2 in oxidative stress-induced endothelial injuries. Journal of Endocrinology 225:3, pages R83-R99.
Crossref
Adam Harvey, Augusto C. Montezano & Rhian M. Touyz. (2015) Vascular biology of ageing—Implications in hypertension. Journal of Molecular and Cellular Cardiology 83, pages 112-121.
Crossref
Matthew J. Socha, Erika M. Boerman, Erik J. Behringer, Rebecca L. Shaw, Timothy L. Domeier & Steven S. Segal. (2015) Advanced age protects microvascular endothelium from aberrant Ca 2+ influx and cell death induced by hydrogen peroxide . The Journal of Physiology 593:9, pages 2155-2169.
Crossref
Kamelija Zarkovic, Pauline Larroque-Cardoso, Mélanie Pucelle, Robert Salvayre, Georg Waeg, Anne Nègre-Salvayre & Neven Zarkovic. (2015) Elastin aging and lipid oxidation products in human aorta. Redox Biology 4, pages 109-117.
Crossref
Aimin Qiao, Yihai Wang, Limin Xiang, Zhenxue Zhang & Xiangjiu He. (2015) Novel triterpenoids isolated from hawthorn berries functioned as antioxidant and antiproliferative activities. Journal of Functional Foods 13, pages 308-313.
Crossref
Luisa B. Maia & José J. G. Moura. (2015) Nitrite reduction by molybdoenzymes: a new class of nitric oxide-forming nitrite reductases. JBIC Journal of Biological Inorganic Chemistry 20:2, pages 403-433.
Crossref
Christos Rammos, Matthias Totzeck, René Deenen, Karl Köhrer, Malte Kelm, Tienush Rassaf & Ulrike B. Hendgen-Cotta. (2015) Dietary Nitrate Is a Modifier of Vascular Gene Expression in Old Male Mice. Oxidative Medicine and Cellular Longevity 2015, pages 1-12.
Crossref
Jessica R. Santos-Parker, Thomas J. LaRocca & Douglas R. Seals. (2014) Aerobic exercise and other healthy lifestyle factors that influence vascular aging. Advances in Physiology Education 38:4, pages 296-307.
Crossref
Peijian Wang, Binghu Li, Guocai Cai, Mingqing Huang, Licheng Jiang, Jing Pu, Lu Li, Qi Wu, Li Zuo, Qiulin Wang & Peng Zhou. (2014) Activation of PPAR-γ by Pioglitazone Attenuates Oxidative Stress in Aging Rat Cerebral Arteries Through Upregulating UCP2. Journal of Cardiovascular Pharmacology 64:6, pages 497-506.
Crossref
David C. Irwin, Chrystelle V. Garat, Joseph T. CrossnoJr.Jr., Paul S. MacLean, Timothy M. Sullivan, Paul F. Erickson, Matthew R. Jackman, Julie W. Harral, Jane E. B. Reusch & Dwight J. Klemm. (2014) Obesity‐Related Pulmonary Arterial Hypertension in Rats Correlates with Increased Circulating Inflammatory Cytokines and Lipids and with Oxidant Damage in the Arterial Wall but not with Hypoxia. Pulmonary Circulation 4:4, pages 638-653.
Crossref
María Esther Rubio-Ruiz, Israel Pérez-Torres, María Elena Soto, Gustavo Pastelín & Verónica Guarner-Lans. (2014) Aging in blood vessels. Medicinal agents FOR systemic arterial hypertension in the elderly. Ageing Research Reviews 18, pages 132-147.
Crossref
Aimin Qiao, Yihai Wang, Limin Xiang, Zhenxue Zhang & Xiangjiu He. (2014) Triterpenoids of sour jujube show pronounced inhibitory effect on human tumor cells and antioxidant activity. Fitoterapia 98, pages 137-142.
Crossref
Carmela R. Balistreri, Calogera Pisano, Adriana Martorana, Oreste F. Triolo, Domenico Lio, Giuseppina Candore & Giovanni Ruvolo. (2014) Are the leukocyte telomere length attrition and telomerase activity alteration potential predictor biomarkers for sporadic TAA in aged individuals?. AGE 36:5.
Crossref
Douglas R. Seals. (2014) Edward F. Adolph Distinguished Lecture: The remarkable anti-aging effects of aerobic exercise on systemic arteries. Journal of Applied Physiology 117:5, pages 425-439.
Crossref
YouYi Zhang & ErDan Dong. (2014) New insight into vascular homeostasis and injury-reconstruction. Science China Life Sciences 57:8, pages 739-741.
Crossref
Douglas R. Seals, Rachelle E. Kaplon, Rachel A. Gioscia-Ryan & Thomas J. LaRocca. (2014) You're Only as Old as Your Arteries: Translational Strategies for Preserving Vascular Endothelial Function with Aging. Physiology 29:4, pages 250-264.
Crossref
Rachel A. Gioscia-Ryan, Thomas J. LaRocca, Amy L. Sindler, Melanie C. Zigler, Michael P. Murphy & Douglas R. Seals. (2014) Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice. The Journal of Physiology 592:12, pages 2549-2561.
Crossref
Nihal Tümer, Hale Z. Toklu, Judy M. Muller-Delp, Şehkar Oktay, Payal Ghosh, Kevin Strang, Michael D. Delp & Philip J. Scarpace. (2014) The effects of aging on the functional and structural properties of the rat basilar artery. Physiological Reports 2:6, pages e12031.
Crossref
Luisa B. Maia & José J. G. Moura. (2014) How Biology Handles Nitrite. Chemical Reviews 114:10, pages 5273-5357.
Crossref
Paiwan Buachan, Linda Chularojmontri & Suvara Wattanapitayakul. (2014) Selected Activities of Citrus Maxima Merr. Fruits on Human Endothelial Cells: Enhancing Cell Migration and Delaying Cellular Aging. Nutrients 6:4, pages 1618-1634.
Crossref
Robert J. Saphirstein & Kathleen G. Morgan. (2014) The Contribution of Vascular Smooth Muscle to Aortic Stiffness Across Length Scales. Microcirculation 21:3, pages 201-207.
Crossref
Carmela Rita BalistreriEmiliano MaresiCalogera PisanoFederica Maria Di MaggioLoredana VaccarinoCalogero CarusoDomenico LioGiovanni RuvoloGiuseppina Candore. (2014) Identification of Three Particular Morphological Phenotypes in Sporadic Thoracic Aortic Aneurysm: Phenotype III As Sporadic Thoracic Aortic Aneurysm Biomarker in Aged Individuals. Rejuvenation Research 17:2, pages 192-196.
Crossref
Xiao Guo, Yang Yu, Xixi Liu, Yinlong Zhang, Tuchen Guan, Guiqiu Xie & Jingyan Wei. (2014) Heterologous expression and characterization of human cellular glutathione peroxidase mutants. IUBMB Life 66:3, pages 212-219.
Crossref
Mor-Li Hartman, Orian S Shirihai, Monika Holbrook, Guoquan Xu, Marsha Kocherla, Akash Shah, Jessica L Fetterman, Matthew A Kluge, Alissa A Frame, Naomi M Hamburg & Joseph A Vita. (2014) Relation of mitochondrial oxygen consumption in peripheral blood mononuclear cells to vascular function in type 2 diabetes mellitus. Vascular Medicine 19:1, pages 67-74.
Crossref
Ying Zhao, Yanbo Yu, Xiaoli Tian, Xi Yang, Xueqi Li, Feng Jiang, Yundai Chen & Maowei Shi. (2014) Association Study to Evaluate FoxO1 and FoxO3 Gene in CHD in Han Chinese. PLoS ONE 9:1, pages e86252.
Crossref
Junzhen Wu, Shijin Xia, Bill Kalionis, Wenbin Wan & Tao Sun. (2014) The Role of Oxidative Stress and Inflammation in Cardiovascular Aging. BioMed Research International 2014, pages 1-13.
Crossref
Iveta Bernatova. (2014) Endothelial Dysfunction in Experimental Models of Arterial Hypertension: Cause or Consequence?. BioMed Research International 2014, pages 1-14.
Crossref
Giovanni Ruvolo, Calogera Pisano, Giuseppina Candore, Domenico Lio, Cesira Palmeri, Emiliano Maresi & Carmela R. Balistreri. (2014) Can the TLR-4-Mediated Signaling Pathway Be “A Key Inflammatory Promoter for Sporadic TAA”?. Mediators of Inflammation 2014, pages 1-14.
Crossref
Christos Rammos, Ulrike B. Hendgen-Cotta, Rene Deenen, Julia Pohl, Pia Stock, Christian Hinzmann, Malte Kelm & Tienush Rassaf. (2014) Age-related vascular gene expression profiling in mice. Mechanisms of Ageing and Development 135, pages 15-23.
Crossref
Javier Díez. 2014. Blood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases. Blood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases 205 213 .
Carolyn M. RoosMichael HaglerBin ZhangElise A. Oehler, Arman ArghamiJordan D. Miller. (2013) Transcriptional and phenotypic changes in aorta and aortic valve with aging and MnSOD deficiency in mice. American Journal of Physiology-Heart and Circulatory Physiology 305:10, pages H1428-H1439.
Crossref
Erik J. BehringerRebecca L. ShawErika B. WestcottMatthew J. SochaSteven S. Segal. (2013) Aging Impairs Electrical Conduction Along Endothelium of Resistance Arteries Through Enhanced Ca2+-Activated K + Channel Activation . Arteriosclerosis, Thrombosis, and Vascular Biology 33:8, pages 1892-1901.
Crossref
Boon How Chew, Sazlina Shariff Ghazali, Mastura Ismail, Jamaiyah Haniff & Mohd Adam Bujang. (2013) Age ≥60years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus. Experimental Gerontology 48:5, pages 485-491.
Crossref
Vikas KumarTimothy Dean CalamarasDagmar HaeusslerWilson Steven ColucciRichard Alan CohenMark Errol McCombDavid PimentelMarkus Michael Bachschmid. (2012) Cardiovascular Redox and Ox Stress Proteomics. Antioxidants & Redox Signaling 17:11, pages 1528-1559.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.