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REVIEW ARTICLE

Molecular hydrogen: An inert gas turns clinically effective

Pages 301-304 | Received 23 Feb 2015, Accepted 24 Mar 2015, Published online: 04 May 2015

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Tyler W LeBaron, Ram B Singh, Ghizal Fatima, Kumar Kartikey, Jagdish P Sharma, Sergej M Ostojic, Anna Gvozdjakova, Branislav Kura, Mami Noda, Viliam Mojto, Mohammad Arif Niaz & Jan Slezak. (2020) The Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial. Diabetes, Metabolic Syndrome and Obesity 13, pages 889-896.
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Hennie Marie Johnsen, Marianne Hiorth & Jo Klaveness. (2023) Molecular Hydrogen Therapy—A Review on Clinical Studies and Outcomes. Molecules 28:23, pages 7785.
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Md. Habibur Rahman, Johny Bajgai, Subham Sharma, Eun-Sook Jeong, Seong Hoon Goh, Yeon-Gyu Jang, Cheol-Su Kim & Kyu-Jae Lee. (2023) Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial. Antioxidants 12:6, pages 1241.
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Nikola Todorovic, Julen Fernández-Landa, Asier Santibañez, Branislav Kura, Valdemar Stajer, Darinka Korovljev & Sergej M. Ostojic. (2023) The Effects of Hydrogen-Rich Water on Blood Lipid Profiles in Clinical Populations: A Systematic Review and Meta-Analysis. Pharmaceuticals 16:2, pages 142.
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Johny Bajgai, Cheol-Su Kim, Md. Habibur Rahman, Eun-Sook Jeong, Hong-Young Jang, Ka-Eun Kim, JaeHo Choi, Il-Young Cho, Kyu-Jae Lee & Mihyun Lee. (2022) Effects of Alkaline-Reduced Water on Gastrointestinal Diseases. Processes 10:1, pages 87.
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Yuan-Zhe Jing, Shu-Jin Li & Zhi-Jun Sun. (2021) Gas and gas-generating nanoplatforms in cancer therapy. Journal of Materials Chemistry B 9:41, pages 8541-8557.
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Md. Habibur Rahman, Johny Bajgai, Ailyn Fadriquela, Subham Sharma, Thuy Trinh Thi, Rokeya Akter, Seong Hoon Goh, Cheol-Su Kim & Kyu-Jae Lee. (2021) Redox Effects of Molecular Hydrogen and Its Therapeutic Efficacy in the Treatment of Neurodegenerative Diseases. Processes 9:2, pages 308.
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Johny Bajgai, Kyu-Jae Lee, Md. Habibur Rahman, Ailyn Fadriquela & Cheol-Su Kim. (2021) Role of Molecular Hydrogen in Skin Diseases and its Impact in Beauty. Current Pharmaceutical Design 27:5, pages 737-746.
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Sergej M. Ostojic. (2021) Hydrogen Gas as an Exotic Performance-Enhancing Agent: Challenges and Opportunities. Current Pharmaceutical Design 27:5, pages 723-730.
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Naoya Okumura, Naoya Jinno, Kentaro Taniguchi, Kenichi Tanabe, Sadako Nakamura, Takaharu Kondo & Akito Shimouchi. (2020) Effects of Cooking Processes on Breath Hydrogen and Colonic Fermentation of Soybean. Current Nutrition & Food Science 16:4, pages 488-493.
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Yanmei Tang, Sihan Lin, Shi Yin, Fei Jiang, Mingliang Zhou, Guangzheng Yang, Ningjia Sun, Wenjie Zhang & Xinquan Jiang. (2020) In situ gas foaming based on magnesium particle degradation: A novel approach to fabricate injectable macroporous hydrogels. Biomaterials 232, pages 119727.
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Yuan Li, Hongguang Chen, Ruichen Shu, Xiaobei Zhang, Yonghao Yu, Xiaofeng Liu & Kuibin Xu. (2020) Hydrogen treatment prevents lipopolysaccharide-induced pulmonary endothelial cell dysfunction through RhoA inhibition. Biochemical and Biophysical Research Communications 522:2, pages 499-505.
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Weifeng Yao, Xiaoyu Lin, Xue Han, Lanfen Zeng, Anshun Guo, Yu Guan, Ziqing Hei, Jianpei Liu & Pinjie Huang. (2020) MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline. Bioscience Reports 40:1.
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Sergej M. Ostojic. (2020) Hydrogen Studies at ClinicalTrials.gov: The Dawn of a New Era?. The American Journal of the Medical Sciences 359:1, pages 51-53.
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Sai Li, Rongrong Liao, Xiaoyan Sheng, Xiaojun Luo, Xin Zhang, Xiaomin Wen, Jin Zhou & Kang Peng. (2019) Hydrogen Gas in Cancer Treatment. Frontiers in Oncology 9.
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Sergej M. Ostojic. (2019) Are there natural spring waters rich in molecular hydrogen?. Trends in Food Science & Technology 90, pages 157.
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Gaoxin Zhou, Ekta Goshi & Qianjun He. (2019) Micro/Nanomaterials‐Augmented Hydrogen Therapy. Advanced Healthcare Materials 8:16, pages 1900463.
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Ping Zhou, Bing Lin, Peng Wang, Tao Pan, Shun Wang, Weisi Chen, Shaowen Cheng & Sha Liu. (2019) The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats. Journal of Radiation Research 60:1, pages 17-22.
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Valter H. Carvalho-Silva, Eduardo C. Vaz, Nayara D. Coutinho, Hikaru Kobayashi, Yuki Kobayashi, Toshio Kasai, Federico Palazzetti, Andrea Lombardi & Vincenzo Aquilanti. 2019. Computational Science and Its Applications – ICCSA 2019. Computational Science and Its Applications – ICCSA 2019 450 459 .
Wei Fang, Guizhen Wang, Luyan Tang, Huilin Su, Huyan Chen, Wanqing Liao & Jinhua Xu. (2018) Hydrogen gas inhalation protects against cutaneous ischaemia/reperfusion injury in a mouse model of pressure ulcer. Journal of Cellular and Molecular Medicine 22:9, pages 4243-4252.
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D. Korovljev, T. Trivic, P. Drid & S. M. Ostojic. (2017) Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women. Irish Journal of Medical Science (1971 -) 187:1, pages 85-89.
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Nayara D. Coutinho, Vincenzo Aquilanti, Flávio O. Sanches-Neto, Eduardo C. Vaz & Valter H. Carvalho-Silva. 2018. Computational Science and Its Applications – ICCSA 2018. Computational Science and Its Applications – ICCSA 2018 605 623 .
Daoli Zhao, Tingting Wang & William R. Heineman. (2016) Advances in H2 sensors for bioanalytical applications. TrAC Trends in Analytical Chemistry 79, pages 269-275.
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Daoli Zhao, Tingting Wang, Julia Kuhlmann, Zhongyun Dong, Shuna Chen, Madhura Joshi, Pravahan Salunke, Vesselin N. Shanov, Daeho Hong, Prashant N. Kumta & William R. Heineman. (2016) In vivo monitoring the biodegradation of magnesium alloys with an electrochemical H2 sensor. Acta Biomaterialia 36, pages 361-368.
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Garth L. Nicolson, Gonzalo Ferreira de Mattos, Robert Settineri, Carlos Costa, Rita Ellithorpe, Steven Rosenblatt, James La Valle, Antonio Jimenez & Shigeo Ohta. (2016) Clinical Effects of Hydrogen Administration: From Animal and Human Diseases to Exercise Medicine. International Journal of Clinical Medicine 07:01, pages 32-76.
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Sergej M. Ostojic. (2016) Should hydrogen therapy be included in a musculoskeletal medicine routine?. F1000Research 5, pages 2659.
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