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Annals of Medicine Volume 42, 2010 - Issue 2
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ORIGINAL ARTICLE

A translational bridge between mouse and human models of learned safety

Daniela D. Pollak Department of Neuroscience, Columbia University, New York, NY, USA; Department of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, AustriaCorrespondence[email protected]
,
Michael T. Rogan Department of Neuroscience, Columbia University, New York, NY, USA; Program for Imaging & Cognitive Sciences, PICS, Columbia University, New York, NY, USA
,
Tobias Egner Center for Cognitive Neuroscience, Department of Psychology & Neuroscience, Duke University, NC, USA
,
David L. Perez Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
,
Ted K. Yanagihara Program for Imaging & Cognitive Sciences, PICS, Columbia University, New York, NY, USA
&
Joy Hirsch Department of Neuroscience, Columbia University, New York, NY, USA; Program for Imaging & Cognitive Sciences, PICS, Columbia University, New York, NY, USA; Department of Radiology, Columbia University, New York, NY, USA; Department of Psychology, Columbia University, New York, NY, USA
Pages 127-134 | Received 30 Oct 2009, Accepted 23 Dec 2009, Published online: 02 Feb 2010

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Daniela D. Pollak, Carlos E. Rey & Francisco J. Monje. (2010) Rodent models in depression research: Classical strategies and new directions. Annals of Medicine 42:4, pages 252-264.
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Anna-Lena Zillig, Paul Pauli, Matthias Wieser & Philipp Reicherts. (2023) Better safe than sorry?—On the influence of learned safety on pain perception. PLOS ONE 18:11, pages e0289047.
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Patrick A.F. Laing, Kim L. Felmingham, Christopher G. Davey & Ben J. Harrison. (2022) The neurobiology of Pavlovian safety learning: Towards an acquisition-expression framework. Neuroscience & Biobehavioral Reviews 142, pages 104882.
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Ronald Sladky, Andreas Hahn, Inga-Lisa KarlNicole Geissberger, Georg S. Kranz, Martin Tik, Christoph Kraus, Daniela M. Pfabigan, Andreas Gartus, Rupert Lanzenberger, Claus Lamm & Christian Windischberger. (2022) Dynamic Causal Modeling of the Prefrontal/Amygdala Network During Processing of Emotional Faces. Brain Connectivity 12:7, pages 670-682.
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Jennifer N. Baumgartner, Desiree Quintana, Linda Leija, Nathaniel M. Schuster, Kelly A. Bruno, Joel P. Castellanos & Laura K. Case. (2022) Widespread Pressure Delivered by a Weighted Blanket Reduces Chronic Pain: A Randomized Controlled Trial. The Journal of Pain 23:1, pages 156-174.
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Kathrin LaFaver, Carine W. Maurer, Timothy R. Nicholson & David L. Perez. 2022. Functional Movement Disorder. Functional Movement Disorder 451 457 .
Dorothee Pöhlchen, Marthe Priouret, Miriam S. Kraft, Florian P. Binder, Deniz A. Gürsel, Götz Berberich, Kathrin Koch & Victor I. Spoormaker. (2021) Examining Differences in Fear Learning in Patients With Obsessive-Compulsive Disorder With Pupillometry, Startle Electromyography and Skin Conductance Responses. Frontiers in Psychiatry 12.
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Patrick A.F. Laing & Ben J. Harrison. (2021) Safety learning and the Pavlovian conditioned inhibition of fear in humans: Current state and future directions. Neuroscience & Biobehavioral Reviews 127, pages 659-674.
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Rongzhen Yan, Tianyu Wang, Xiaoyan Ma, Xinyang Zhang, Rui Zheng & Qiang Zhou. (2021) Prefrontal inhibition drives formation and dynamic expression of probabilistic Pavlovian fear conditioning. Cell Reports 36:6, pages 109503.
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Nicholas S. Race, Katharine D. Andrews, Elizabeth A. Lungwitz, Sasha M. Vega Alvarez, Timothy R. Warner, Glen Acosta, Jiayue Cao, Kun-han Lu, Zhongming Liu, Amy D. Dietrich, Sreeparna Majumdar, Anantha Shekhar, William A. Truitt & Riyi Shi. (2021) Psychosocial impairment following mild blast-induced traumatic brain injury in rats. Behavioural Brain Research 412, pages 113405.
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Bohan Zhao, Jiameng Sun, Qian Li & Yi Zhong. (2021) Differential conditioning produces merged long-term memory in Drosophila. eLife 10.
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Hyein Cho, Ekaterina Likhtik & Tracy A. Dennis-Tiwary. (2021) Absence Makes the Mind Grow Fonder: Reconceptualizing Studies of Safety Learning in Translational Research on Anxiety. Cognitive, Affective, & Behavioral Neuroscience 21:1, pages 1-13.
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Jamie N. Krueger & Susan Sangha. (2021) On the basis of sex: Differences in safety discrimination vs. conditioned inhibition. Behavioural Brain Research 400, pages 113024.
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Monika Eckstein, Ilshat Mamaev, Beate Ditzen & Uta Sailer. (2020) Calming Effects of Touch in Human, Animal, and Robotic Interaction—Scientific State-of-the-Art and Technical Advances. Frontiers in Psychiatry 11.
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H. Dou, Y. Lei, X. Cheng, J. Wang & PHT Leppänen. (2020) Social exclusion influences conditioned fear acquisition and generalization: A mediating effect from the medial prefrontal cortex. NeuroImage 218, pages 116735.
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David L Perez. (2020) Persistence of the ‘broken escalator’ phenomenon in functional gait disorder: mechanistic insights. Brain 143:8, pages 2338-2340.
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Birthe Macdonald, Shannon Wake & Tom Johnstone. (2020) Selective extinction through cognitive evaluation: Linking emotion regulation and extinction. European Journal of Neuroscience 52:2, pages 2873-2888.
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Malgorzata H. Kolodziejczyk & Markus Fendt. (2020) Corticosterone Treatment and Incubation Time After Contextual Fear Conditioning Synergistically Induce Fear Memory Generalization in Neuropeptide S Receptor-Deficient Mice. Frontiers in Neuroscience 14.
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Ekaterina Likhtik & Rony Paz. 2020. Stress Resilience. Stress Resilience 323 348 .
Takuya Yoshiike, Motoyasu Honma, Naoto Yamada, Yoshiharu Kim & Kenichi Kuriyama. (2018) Effects of bright light exposure on human fear conditioning, extinction, and associated prefrontal activation. Physiology & Behavior 194, pages 268-276.
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Natalie Dittert, Sandrina Hüttner, Thomas Polak & Martin J. Herrmann. (2018) Augmentation of Fear Extinction by Transcranial Direct Current Stimulation (tDCS). Frontiers in Behavioral Neuroscience 12.
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Christoph W. Korn, Matthias Staib, Athina Tzovara, Giuseppe Castegnetti & Dominik R. Bach. (2017) A pupil size response model to assess fear learning. Psychophysiology 54:3, pages 330-343.
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Laura Leuchs, Max Schneider, Michael Czisch & Victor I. Spoormaker. (2017) Neural correlates of pupil dilation during human fear learning. NeuroImage 147, pages 186-197.
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Laurel S. Morris, Benjaman To, Kwangyeol Baek, Yee-Chien Chang-Webb, Simon Mitchell, Daniela Strelchuk, Yevheniia Mikheenko, Wendy Phillips, Michael Zandi, Allison Jenaway, Cathy Walsh & Valerie Voon. (2017) Disrupted avoidance learning in functional neurological disorder: Implications for harm avoidance theories. NeuroImage: Clinical 16, pages 286-294.
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Kevin Lloyd & Peter Dayan. (2016) Safety out of control: dopamine and defence. Behavioral and Brain Functions 12:1.
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Franziska Labrenz, Adriane Icenhour, Marc Schlamann, Michael Forsting, Ulrike Bingel & Sigrid Elsenbruch. (2016) From Pavlov to pain: How predictability affects the anticipation and processing of visceral pain in a fear conditioning paradigm. NeuroImage 130, pages 104-114.
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Adriane Icenhour, Joswin Kattoor, Sven Benson, Armgard Boekstegers, Marc Schlamann, Christian J. Merz, Michael Forsting & Sigrid Elsenbruch. (2015) Neural circuitry underlying effects of context on human pain-related fear extinction in a renewal paradigm. Human Brain Mapping 36:8, pages 3179-3193.
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Anna Zilverstand, Bettina Sorger, Pegah Sarkheil & Rainer Goebel. (2015) fMRI neurofeedback facilitates anxiety regulation in females with spider phobia. Frontiers in Behavioral Neuroscience 9.
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Ronald Sladky, Anna Höflich, Martin Küblböck, Christoph Kraus, Pia Baldinger, Ewald Moser, Rupert Lanzenberger & Christian Windischberger. (2015) Disrupted Effective Connectivity Between the Amygdala and Orbitofrontal Cortex in Social Anxiety Disorder During Emotion Discrimination Revealed by Dynamic Causal Modeling for fMRI. Cerebral Cortex 25:4, pages 895-903.
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Ekaterina Likhtik & Rony Paz. (2015) Amygdala–prefrontal interactions in (mal)adaptive learning. Trends in Neurosciences 38:3, pages 158-166.
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Jony Sheynin, Kevin D. Beck, Richard J. Servatius & Catherine E. Myers. (2014) Acquisition and Extinction of Human Avoidance Behavior: Attenuating Effect of Safety Signals and Associations with Anxiety Vulnerabilities. Frontiers in Behavioral Neuroscience 8.
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Joseph M. Stujenske, Ekaterina Likhtik, Mihir A. Topiwala & Joshua A. Gordon. (2014) Fear and Safety Engage Competing Patterns of Theta-Gamma Coupling in the Basolateral Amygdala. Neuron 83:4, pages 919-933.
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Ilana J. Bennett & Bart Rypma. (2013) Advances in functional neuroanatomy: A review of combined DTI and fMRI studies in healthy younger and older adults. Neuroscience & Biobehavioral Reviews 37:7, pages 1201-1210.
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Ronald Sladky, Anna Höflich, Jacqueline Atanelov, Christoph Kraus, Pia Baldinger, Ewald Moser, Rupert Lanzenberger & Christian Windischberger. (2012) Increased Neural Habituation in the Amygdala and Orbitofrontal Cortex in Social Anxiety Disorder Revealed by fMRI. PLoS ONE 7:11, pages e50050.
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Tetsuya Iidaka, Tokiko Harada & Norihiro Sadato. (2011) Forming a negative impression of another person correlates with activation in medial prefrontal cortex and amygdala. Social Cognitive and Affective Neuroscience 6:4, pages 516-525.
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Daniela D Pollak, Francisco J Monje & Gert Lubec. (2010) The learned safety paradigm as a mouse model for neuropsychiatric research. Nature Protocols 5:5, pages 954-962.
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