Advanced search
Publication Cover
Annals of Medicine Volume 29, 1997 - Issue 4
Submit an article Journal homepage
414
Views
65
CrossRef citations to date
0
Altmetric
Original Article

Cytokines and Cardiomyocyte Death

Kari J. Pulkki Department of Clinical Chemistry, University of Turku, Turku, FinlandCorrespondence[email protected]
Pages 339-343 | Published online: 08 Jul 2009

Citations (65)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Ivan Dimauro, Fiorenza Magi, Gina La Sala, Monica Pittaluga, Paolo Parisi & Daniela Caporossi. (2011) Modulation of the apoptotic pathway in skeletal muscle models: the role of growth hormone. Growth Factors 29:1, pages 21-35.
Read now
Magdalena Birker‐Robaczewska, Céline Boukhadra, Rolf Studer, Célia Mueller, Christoph Binkert & Oliver Nayler. (2003) The Expression of Urotensin II Receptor (U2R) is Up‐regulated by Interferon‐γ. Journal of Receptors and Signal Transduction 23:4, pages 289-305.
Read now
Heli Koukkunen, Karri Penttilä, Art Kemppainen, Matti Halinen, Ilkka Penttilä, Tapio Rantanen & Kalevi Pyörälä. (2001) C-reactive protein, fibrinogen, interleukin-6 and tumour necrosis factor-α in the prognostic classification of unstable angina pectoris. Annals of Medicine 33:1, pages 37-47.
Read now

Articles from other publishers (62)

Shi-Hao Ni, Jin-Dong Xu, Shu-Ning Sun, Yue Li, Zheng Zhou, Huan Li, Xin Liu, Jian-Ping Deng, Yu-Sheng Huang, Zi-Xin Chen, Wen-Jun Feng, Jia-Jia Wang, Shao-Xiang Xian, Zhong-Qi Yang, Sheng Wang, Ling-Jun Wang & Lu Lu. (2022) Single-cell transcriptomic analyses of cardiac immune cells reveal that Rel-driven CD72-positive macrophages induce cardiomyocyte injury. Cardiovascular Research 118:5, pages 1303-1320.
Crossref
Xiaofeng Li, Ligong Bian, Xi Zhao, Dan He, Guohua Liu, Di Wei Tang, Zhiqin Li & Junzi Wu. (2021) Nanoparticles capable of managing hypoglycemia and preventing myocardial ischemia‐reperfusion injury. Journal of Applied Polymer Science 139:10, pages 51758.
Crossref
Abhigyan Choudhury & Suprabhat Mukherjee. (2021) Taming the Storm in the Heart: Exploring Different Therapeutic Choices Against Myocardial Inflammation in COVID-19. Recent Advances in Anti-Infective Drug Discovery 16:2, pages 89-93.
Crossref
Bibhuti B. Das, S. Kristen Sexon Tejtel, Shriprasad Deshpande & Lara S. Shekerdemian. (2021) A Review of the Cardiac and Cardiovascular Effects of COVID-19 in Adults and Children. Texas Heart Institute Journal 48:3.
Crossref
Georgina M. Ellison-Hughes, Liam Colley, Katie A. O'Brien, Kirsty A. Roberts, Thomas A. Agbaedeng & Mark D. Ross. (2020) The Role of MSC Therapy in Attenuating the Damaging Effects of the Cytokine Storm Induced by COVID-19 on the Heart and Cardiovascular System. Frontiers in Cardiovascular Medicine 7.
Crossref
Saltanat Zhazykbayeva, Steffen Pabel, Andreas Mügge, Samuel Sossalla & Nazha Hamdani. (2020) The molecular mechanisms associated with the physiological responses to inflammation and oxidative stress in cardiovascular diseases. Biophysical Reviews 12:4, pages 947-968.
Crossref
Lei Zhang, Ying Yu, Peng Yu, Jian Wu, Aijun Sun, Yunzeng Zou, Yangang Su, Hong Jiang & Junbo Ge. (2020) HMGB1 Aggravates Pressure Overload-Induced Left Ventricular Dysfunction by Promoting Myocardial Fibrosis. International Journal of Hypertension 2020, pages 1-8.
Crossref
Xingdi Zhou, Ni Xia, Bingjie Lv, Tingting Tang, Shaofang Nie, Min Zhang, Jiao Jiao, Jianfeng Liu, Chanjuan Xu, Guofei Hou, Xiangping Yang, Yu Hu, Yuhua Liao & Xiang Cheng. (2020) Interleukin 35 ameliorates myocardial ischemia‐reperfusion injury by activating the gp130‐STAT3 axis. The FASEB Journal 34:2, pages 3224-3238.
Crossref
Sumit Kar, Tyler N. Kambis & Paras K. Mishra. (2019) Hydrogen sulfide-mediated regulation of cell death signaling ameliorates adverse cardiac remodeling and diabetic cardiomyopathy. American Journal of Physiology-Heart and Circulatory Physiology 316:6, pages H1237-H1252.
Crossref
Svenja HinrichsKatharina ScherschelSaskia Krüger, Johannes Tobias NeumannMichael SchwarzlIsabell YanSvenja WarnkeFrancisco M. OjedaTanja ZellerMahir KarakasTill Keller, Christian MeyerStefan BlankenbergDirk WestermannDiana Lindner. (2018) Precursor proadrenomedullin influences cardiomyocyte survival and local inflammation related to myocardial infarction. Proceedings of the National Academy of Sciences 115:37.
Crossref
Miłosz Kawa, Iwona Stecewicz, Katarzyna Piecyk, Edyta Paczkowska, Dorota Rogińska, Anna Sobuś, Karolina Łuczkowska, Ewa Pius-Sadowska, Elżbieta Gawrych, Elżbieta Petriczko, Mieczysław Walczak & Bogusław Machaliński. (2017) The Impact of Growth Hormone Therapy on the Apoptosis Assessment in CD34+ Hematopoietic Cells from Children with Growth Hormone Deficiency. International Journal of Molecular Sciences 18:1, pages 111.
Crossref
Young Mi HongHyeryon LeeMin-Sun ChoKwan Chang Kim. (2017) Apoptosis and remodeling in adriamycin-induced cardiomyopathy rat model. Korean Journal of Pediatrics 60:11, pages 365.
Crossref
Li Yue-Chun, Chen Guang-Yi, Ge Li-Sha, Xing Chao, Tian Xinqiao, Lin Cong, Dai Xiao-Ya & Yang Xiangjun. (2016) The Protective Effects of Ivabradine in Preventing Progression from Viral Myocarditis to Dilated Cardiomyopathy. Frontiers in Pharmacology 7.
Crossref
Kyung Jong Won, Kang Pa Lee, Suyeol Yu, Donghyen Lee, Dong-Youb Lee, Hwan Myung Lee, Junghwan Kim, Seung Hyo Jung, Suji Baek & Bokyung Kim. (2015) Ketoconazole induces apoptosis in rat cardiomyocytes through reactive oxygen species-mediated parkin overexpression. Archives of Toxicology 89:10, pages 1871-1880.
Crossref
Peter N Liersch, Andreas Schwarz, Joerg Sachweh, Benita Hermanns-Sachweh, Ruth Heying, Jaime F Vázquez-Jimènez, Adelin Albert & Marie-Christine Seghaye. (2015) Gene expression of cytokines, growth factors and apoptosis regulators in a neonatal model of pulmonary stenosis. Future Cardiology 11:3, pages 297-307.
Crossref
M. Caliskan, H. Gullu, D. Erdogan, M. Ozulku, S. Kulaksızoglu, O. Ciftci & H. Muderrisoglu. (2014) Association between serum total antioxidant status and coronary microvascular function in idiopathic dilated cardiomyopathyZusammenhang zwischen Gesamtantioxidanzienstatus im Serum und mikrovaskulärer koronarer Funktion bei idiopathischer dilatativer Kardiomyopathie. Herz 40:3, pages 487-494.
Crossref
Kang Pa LeeJai-Eun KimWon-Hwan Park. (2015) Cytoprotective effect of rhamnetin on miconazole-induced H9c2 cell damage. Nutrition Research and Practice 9:6, pages 586.
Crossref
Amanda Farage Frade, Priscila Camilo Teixeira, Barbara Maria Ianni, Cristina Wide Pissetti, Bruno Saba, Lin Hui Tzu Wang, Andréia Kuramoto, Luciana Gabriel Nogueira, Paula Buck, Fabrício Dias, Helene Giniaux, Agnes Llored, Sthefanny Alves, Andre Schmidt, Eduardo Donadi, José Antonio Marin-Neto, Mario Hirata, Marcelo Sampaio, Abílio Fragata, Edimar Alcides Bocchi, Antonio Noedir Stolf, Alfredo Inacio Fiorelli, Ronaldo Honorato Barros Santos, Virmondes Rodrigues, Alexandre Costa Pereira, Jorge Kalil, Edecio Cunha-Neto & Christophe Chevillard. (2013) Polymorphism in the Alpha Cardiac Muscle Actin 1 Gene Is Associated to Susceptibility to Chronic Inflammatory Cardiomyopathy. PLoS ONE 8:12, pages e83446.
Crossref
Man-Yi Ren & Shu-Jian Sui. (2012) The role of TWEAK/Fn14 in cardiac remodeling. Molecular Biology Reports 39:11, pages 9971-9977.
Crossref
Eduardo Roggero, Johannes Wildmann, Marcelo O. Passerini, Adriana del Rey & Hugo O. Besedovsky. (2012) Different peripheral neuroendocrine responses to Trypanosoma cruzi infection in mice lacking adaptive immunity. Annals of the New York Academy of Sciences 1262:1, pages 37-44.
Crossref
Offer Amir, Ilia Spivak, Idit Lavi & Michal Amit Rahat. (2012) Changes in the Monocytic Subsets CD14 dim CD16 + and CD14 ++ CD16 − in Chronic Systolic Heart Failure Patients . Mediators of Inflammation 2012, pages 1-9.
Crossref
Denis V. Abramochkin, Ekaterina Yu. Makarenko, Vadim M. Mitrochin, Bo Tian, Vlad S. Kuzmin, Leonid Kalugin, Leonid V. Kovalchuk, Marina V. Khoreva, Anna Nikonova, Ilya Lozinsky & Andre Kamkin. 2012. Mechanical Stretch and Cytokines. Mechanical Stretch and Cytokines 155 164 .
Mariantonietta Cicoira, Stefan D. Anker & Claudio Ronco. (2011) Cardio‐renal cachexia syndromes (CRCS): pathophysiological foundations of a vicious pathological circle. Journal of Cachexia, Sarcopenia and Muscle 2:3, pages 135-142.
Crossref
Emanuele Marzetti, Stephanie E. Wohlgemuth, Stephen D. Anton, Roberto Bernabei, Christy S. Carter & Christiaan Leeuwenburgh. (2009) Cellular Mechanisms of Cardioprotection by Calorie Restriction: State of the Science and Future Perspectives. Clinics in Geriatric Medicine 25:4, pages 715-732.
Crossref
Kuljeet Kaur, Sanjiv Dhingra, Jan Slezak, Anita K. Sharma, Anju Bajaj & Pawan K. Singal. (2008) Biology of TNFα and IL-10, and their imbalance in heart failure. Heart Failure Reviews 14:2, pages 113-123.
Crossref
Geanete Pozzan, Carla Pagliari, Felipe Francisco Tuon, Cleusa Fumika Takakura, Monica R. Kauffman & Maria Irma Seixas Duarte. (2009) Diffuse-regressive alterations and apoptosis of myocytes: Possible causes of myocardial dysfunction in HIV-related cardiomyopathy. International Journal of Cardiology 132:1, pages 90-95.
Crossref
Angela Kallwellis-Opara, Andrea Dörner, Wolfgang-Christian Poller, Michel Noutsias, Uwe Kühl, Heinz-Peter Schultheiss & Mathias Pauschinger. (2007) Autoimmunological features in inflammatory cardiomyopathy. Clinical Research in Cardiology 96:7, pages 469-480.
Crossref
Abdolkarim Sheikhi, Yahya Jaberi, Abdolreza Esmaeilzad, Mohammad Khani, Mehdi Moosaeefar & Mostafa Shafaqatia. (2007) The Effect of Cardiovascular Drugs on Pro-Inflammatory Cytokine Secretion and Natural Killer Activity of Peripheral Blood Mononuclear Cells of Patients with Chronic Heart Failure in vitro. Pakistan Journal of Biological Sciences 10:10, pages 1580-1587.
Crossref
Robert J. Henning, Jose D. Burgos, Leo Ondrovic, Paul Sanberg, John Balis & Michael B. Morgan. (2017) Human Umbilical Cord Blood Progenitor Cells are Attracted to Infarcted Myocardium and Significantly Reduce Myocardial Infarction Size. Cell Transplantation 15:7, pages 647-658.
Crossref
Elliott Kagan. (2006) Bioregulators as Prototypic Nontraditional Threat Agents. Clinics in Laboratory Medicine 26:2, pages 421-443.
Crossref
Amilcar O. Mocelin, Victor S. Issa, Fernando Bacal, Guilherme V. Guimarães, Edecio Cunha & Edimar A. Bocchi. (2005) The influence of aetiology on inflammatory and neurohumoral activation in patients with severe heart failure: A prospective study comparing Chagas' heart disease and idiopathic dilated cardiomyopathy. European Journal of Heart Failure 7:5, pages 869-873.
Crossref
Dimitris Tousoulis, Marietta Charakida & Christodoulos Stefanadis. (2005) Inflammation and endothelial dysfunction as therapeutic targets in patients with heart failure. International Journal of Cardiology 100:3, pages 347-353.
Crossref
Patrick J. Perik, Elisabeth G.E. de Vries, Jourik A. Gietema, Winette T.A. van der Graaf, Dirk Th. Sleijfer, Albert J.H. Suurmeijer & D.J. van Veldhuisen. (2005) The dilemma of the strive for apoptosis in oncology: mind the heart. Critical Reviews in Oncology/Hematology 53:2, pages 101-113.
Crossref
Costas Tentolouris, Dimitris Tousoulis, Charalambos Antoniades, Eirini Bosinakou, Maria Kotsopoulou, Athanasios Trikas, Pavlos Toutouzas & Christodoulos Stefanadis. (2004) Endothelial function and proinflammatory cytokines in patients with ischemic heart disease and dilated cardiomyopathy. International Journal of Cardiology 94:2-3, pages 301-305.
Crossref
Anita S. Galvez, Juan Alberto Ulloa, Mario Chiong, Alfredo Criollo, Verónica Eisner, Luis Felipe Barros & Sergio Lavandero. (2003) Aldose Reductase Induced by Hyperosmotic Stress Mediates Cardiomyocyte Apoptosis. Journal of Biological Chemistry 278:40, pages 38484-38494.
Crossref
Andreas Jeron, Tanja Kaiser, Rainer H Straub, Joachim Weil, Günter A.J Riegger & Frank Muders. (2003) Myocardial IL-6 regulation by neurohormones—an in vitro superfusion study. Brain, Behavior, and Immunity 17:4, pages 245-250.
Crossref
J.B. Sundstrom, D.E. Martinson, M. Mosunjac, P. Bostik, L.K. McMullan, R.M. Donahoe, M.B. Gravanis & A.A. Ansari. (2016) Norepinephrine Enhances Adhesion of HIV-1-Infected Leukocytes to Cardiac Microvascular Endothelial Cells. Experimental Biology and Medicine 228:6, pages 730-740.
Crossref
Ma Qing, Kathrin Schumacher, Ruth Heise, Michael Wöltje, Jaime F Vazquez-Jimenez, Thomas Richter, Monika Arranda-Carrero, John Hess, Götz von Bernuth & Marie-Christine Seghaye. (2003) Intramyocardial synthesis of pro- and anti-inflammatory cytokines in infants with congenital cardiac defects. Journal of the American College of Cardiology 41:12, pages 2266-2274.
Crossref
Simona Cicconi, Natascia Ventura, Donatella Pastore, Paolo Bonini, Paolo Di Nardo, Renato Lauro & Lionel N.J.L. Marlier. (2003) Characterization of apoptosis signal transduction pathways in HL-5 cardiomyocytes exposed to ischemia/reperfusion oxidative stress model. Journal of Cellular Physiology 195:1, pages 27-37.
Crossref
Merilee F. Costello, Cynthia M. Otto & Leona J. Rubin. (2003) The role of tumor necrosis factor-α (TNF-α) and the sphingosine pathway in sepsis-induced myocardial dysfunction. Journal of Veterinary Emergency and Critical Care 13:1, pages 25-34.
Crossref
ANDREA HENRIQUES‐PONS, GABRIEL M. OLIVEIRA, MAURICIO M. PAIVA, ALEXANDRE F. S. CORREA, MARCOS M. BATISTA, RODRIGO C. BISAGGIO, CHAU‐CHING LIU, VINÍCIUS COTTA‐DE‐ALMEIDA, CLAUDIA M. L. M. COUTINHO, PEDRO M. PERSECHINI & TANIA C. ARAÚJO‐JORGE. (2002) Evidence for a perforin‐mediated mechanism controlling cardiac inflammation in Trypanosoma cruzi infection . International Journal of Experimental Pathology 83:2, pages 67-79.
Crossref
Per Ole IversenPer Reidar Woldbaek, Theis Tønnessen & Geir Christensen. (2002) Decreased hematopoiesis in bone marrow of mice with congestive heart failure. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 282:1, pages R166-R172.
Crossref
Charles Blais Jr.Nathalie Lapointe, Jean-Lucien Rouleau, Robert Clément, Dimcho R Bachvarov & Albert Adam. (2002) Effects of captopril and omapatrilat on early post-myocardial infarction survival and cardiac hemodynamics in rats: interaction with cardiac cytokine expression. Canadian Journal of Physiology and Pharmacology 80:1, pages 48-58.
Crossref
J.D Sackner-Bernstein. (2002) Activation and release of degradative proteinases within the myocardium are the trigger for ventricular remodeling in chronic heart failure. Medical Hypotheses 58:1, pages 18-23.
Crossref
Per Ole Iversen, Gunnar Nicolaysen & Mouldy Sioud. (2001) DNA enzyme targeting TNF-α mRNA improves hemodynamic performance in rats with postinfarction heart failure. American Journal of Physiology-Heart and Circulatory Physiology 281:5, pages H2211-H2217.
Crossref
Peter Alter, M. Jobmann, E. Meyer, S. Pankuweit & B. Maisch. (2001) Apoptosis in myocarditis and dilated cardiomyopathy: Does enterovirus genome persistence protect from apoptosis? — An endomyocardial biopsy study. Cardiovascular Pathology 10:5, pages 229-234.
Crossref
Elliott Kagan. (2001) Bioregulators as Instruments of Terror. Clinics in Laboratory Medicine 21:3, pages 607-618.
Crossref
Y J Kang. (2001) Molecular and cellular mechanisms of cardiotoxicity.. Environmental Health Perspectives 109:suppl 1, pages 27-34.
Crossref
Richard A. Lockshin, Caroline O.B. Facey & Zahra Zakeri. (2001) CELL DEATH IN THE HEART. Cardiology Clinics 19:1, pages 1-11.
Crossref
Go Hiasa, Mareomi Hamada, Shuntaro Ikeda & Kunio Hiwada. (2001) Ischemic Preconditioning and Lipopolysaccharide Attenuate Nuclear Factor-.KAPPA.B Activation and Gene Expression of Inflammatory Cytokines in the Ischemia-Reperfused Rat Heart.. Japanese Circulation Journal 65:11, pages 984-990.
Crossref
Treena E. McDonald, Michelle N. Grinman, Chris M. Carthy & Keith R. Walley. (2000) Endotoxin infusion in rats induces apoptotic and survival pathways in hearts. American Journal of Physiology-Heart and Circulatory Physiology 279:5, pages H2053-H2061.
Crossref
L. Calderón-Garcidue~nas, R.B. Devlin & F.J. Miller. (2000) Respiratory tract pathology and cytokine imbalance in clinically healthy children chronically and sequentially exposed to air pollutants. Medical Hypotheses 55:5, pages 373-378.
Crossref
Adrian M Moran, Steven D Colan, Joseph A Majzoub & Jane W Newburger. (2000) Exogenous growth hormone: a new therapy for dilated cardiomyopathy. Progress in Pediatric Cardiology 12:1, pages 125-132.
Crossref
Albrecht Elsässer, Keisuke Suzuki & Jutta Schaper. (2000) Unresolved Issues Regarding the Role of Apoptosis in the Pathogenesis of Ischemic Injury and Heart Failure. Journal of Molecular and Cellular Cardiology 32:5, pages 711-724.
Crossref
María Paz Morales, Anita Gálvez, José Miguel Eltit, Paula Ocaranza, Guillermo Díaz-Araya & Sergio Lavandero. (2000) IGF-1 Regulates Apoptosis of Cardiac Myocyte Induced by Osmotic-Stress. Biochemical and Biophysical Research Communications 270:3, pages 1029-1035.
Crossref
Juan A. Rodríguez-Feo, José Fortes, Ester Aceituno, Jerónimo Farré, Rocío Ayala, Carlos Castilla, Luis Rico, Fernando González-Fernández, Margarita García-Durán, Santos Casado & Antonio López-Farré. (2000) Doxazosin modifies Bcl-2 and Bax protein expression in the left ventricle of spontaneously hypertensive rats. Journal of Hypertension 18:3, pages 307-315.
Crossref
Masahiko Okuno, Masao Nakagawa, Morimi Shimada, Mikiyoshi Saito, Shigemichi Hishinuma & Keiko Yamauchi-Takihara. (2000) Expressional Patterns of Cytokines in a Murine Model of Acute Myocarditis: Early Expression of Cardiotrophin-1. Laboratory Investigation 80:3, pages 433-440.
Crossref
Jonathan D. Sackner-Bernstein. (2000) The myocardial matrix and the development and progression of ventricular remodeling. Current Cardiology Reports 2:2, pages 112-119.
Crossref
Makoto Araki, Masaru Tanaka, Koji Hasegawa, Ryoji Yokota, Takashi Maeda, Makoto Ishikawa, Youichi Yabuuchi & Shigetake Sasayama. (2000) Nitric Oxide Inhibition Improved Myocardial Metabolism Independent of Tissue Perfusion During Ischemia But Not During Reperfusion. Journal of Molecular and Cellular Cardiology 32:3, pages 375-384.
Crossref
Rakesh Sharma, Andrew J.S. Coats & Stefan D. Anker. (2000) The role of inflammatory mediators in chronic heart failure: cytokines, nitric oxide, and endothelin-1. International Journal of Cardiology 72:2, pages 175-186.
Crossref
H. Schumann, H. Heinrich, B. Bartling, D. Darmer & J. Holtz. 2000. From Molecule to Men. From Molecule to Men 33 68 .
Y-S. Huang, Z-C. Yang, B-G. Yan, J-M. Yang, F-M. Chen, R. S. Crowther & A. Li. (1999) Pathogenesis of Early Cardiac Myocyte Damage after Severe Burns. The Journal of Trauma: Injury, Infection, and Critical Care 46:3, pages 428-432.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.