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Original Article

Paraoxonase Genes and Disease

Pages 217-224 | Published online: 08 Jul 2009

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Gary Ginsberg, Patricia Neafsey, Dale Hattis, Kathryn Z. Guyton, Douglas O. Johns & Babasaheb Sonawane. (2009) Genetic Polymorphism in Paraoxonase 1 (PON1): Population Distribution of PON1 Activity. Journal of Toxicology and Environmental Health, Part B 12:5-6, pages 473-507.
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Navin K Kapur, Dominique Ashen & Roger S Blumenthal. (2008) High density lipoprotein cholesterol: an evolving target of therapy in the management of cardiovascular disease. Vascular Health and Risk Management 4:1, pages 39-57.
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Hisashi Shinkai. (2001) Cholesteryl ester transfer protein inhibitors. Expert Opinion on Therapeutic Patents 11:5, pages 739-745.
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Articles from other publishers (62)

Mattia Melloni, Domenico Sergi, Carolina Simioni, Angelina Passaro & Luca Maria Neri. (2023) Microalgae as a Nutraceutical Tool to Antagonize the Impairment of Redox Status Induced by SNPs: Implications on Insulin Resistance. Biology 12:3, pages 449.
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Berrin Göktuğ KADIOĞLU, Aysel NALÇAKAN & Esra DİLEK. (2022) The paraoxonase 1 activity and lipid levels in umbilical cord blood and maternal venous blood, and their relations according to birth weight. The European Research Journal 8:1, pages 9-15.
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Giuseppe Manco, Elena Porzio & Teresa Maria Carusone. (2021) Human Paraoxonase-2 (PON2): Protein Functions and Modulation. Antioxidants 10:2, pages 256.
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Kumari Priyanka, Surjit Singh & Kirandip Gill. (2019) Paraoxonase 3: Structure and Its Role in Pathophysiology of Coronary Artery Disease. Biomolecules 9:12, pages 817.
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Huan Ren, Sheng-Lan Tan, Mou-Ze Liu, Hoan L. Banh & Jian-Quan Luo. (2018) Association of PON2 Gene Polymorphisms (Ser311Cys and Ala148Gly) With the Risk of Developing Type 2 Diabetes Mellitus in the Chinese Population. Frontiers in Endocrinology 9.
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O. Lockridge, D.M. Quinn & Z. Radić. 2018. Comprehensive Toxicology. Comprehensive Toxicology 277 307 .
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Mohamed H?di Sbai, Amani Kallel, Yousra Sediri, Mehdi Lassoued, Moncef Feki, Mohamed Sami Mourali, Naziha Kaabachi & Riadh Jemaa. (2016) Association between paraoxonase-1 gene promoter -108C/T polymorphism and myocardial infarction in the Tunisian male population / Tunuslu erkek populasyonunda miyokard enfarkt?s ile paraoksonaz -1 gen ba?lat?c? -108C/T polimorfizmi aras?ndaki ili?ki. Turkish Journal of Biochemistry 41:2.
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Dalibor Novotny, David Karasek, Helena Vaverkova, Margita Bartkova & Veronika Kubickova. (2015) Paraoxonase 2 Cys311Ser polymorphism and its association with the systolic blood pressure values in asymptomatic dyslipidemic individuals: a pilot study. LaboratoriumsMedizin 39:4, pages 249-257.
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H. .. An-Hahar, O. O. Bolshakova, O. D. Belyaeva, O. A. Berkovich, V. I. Larionova & E. I. Baranova. (2012) Blood pressure, lipid levels and apolipoprotein A1 and paraoxonase 1 gene polymorphisms in patients with abdominal obesity. "Arterial’naya Gipertenziya" ("Arterial Hypertension") 18:3, pages 255-266.
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Zhi-Gang SheHou-Zao ChenYunfei YanHongliang LiDe-Pei Liu. (2012) The Human Paraoxonase Gene Cluster As a Target in the Treatment of Atherosclerosis. Antioxidants & Redox Signaling 16:6, pages 597-632.
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Banu BayramBeraat OzcelikStefanie GrimmThomas RoederCharlotte SchraderInsa M.A. ErnstAnika E. WagnerTilman GruneJan FrankGerald Rimbach. (2012) A Diet Rich in Olive Oil Phenolics Reduces Oxidative Stress in the Heart of SAMP8 Mice by Induction of Nrf2-Dependent Gene Expression. Rejuvenation Research 15:1, pages 71-81.
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Ines Witte, Ulrich Foerstermann, Asokan Devarajan, Srinivasa T. Reddy & Sven Horke. (2012) Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer. Journal of Lipids 2012, pages 1-12.
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Zorica Rasic-Milutinovic, Tamara Popovic, Gordana Perunicic-Pekovic, Aleksandra Arsic, Suncica Borozan & Marija Glibetic. (2012) Lower Serum Paraoxonase-1 Activity Is Related to Linoleic and Docosahexanoic Fatty Acids in Type 2 Diabetic Patients. Archives of Medical Research 43:1, pages 75-82.
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Manal Kamal, Mona M. Fathy, Eman Taher, Manal Hasan & May Tolba. (2011) Assessment of the role of paraoxonase gene polymorphism (Q192R) and paraoxonase activity in the susceptibility to atherosclerosis among lead-exposed workers. Annals of Saudi Medicine 31:5, pages 481-487.
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Somayyeh Karami-Mohajeri & Mohammad Abdollahi. (2010) Toxic influence of organophosphate, carbamate, and organochlorine pesticides on cellular metabolism of lipids, proteins, and carbohydrates. Human & Experimental Toxicology 30:9, pages 1119-1140.
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Manju Sharma, K.K. Pillai, Tarique Anwer, Abul Kalam Najmi, Syed Ehtaishamul Haque & Yasmin Sultana. (2010) Protective effect of silymarin in streptozotocin-induced diabetic dyslipidaemia in rats. Oriental Pharmacy and Experimental Medicine 10:3, pages 165-172.
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Alexandros Zafiropoulos, Manolis Linardakis, Eugene H.J.M. Jansen, Aristidis M. Tsatsakis, Antonis Kafatos & George N. Tzanakakis. (2010) Paraoxonase 1 R/Q alleles are associated with differential accumulation of saturated versus 20:5n3 fatty acid in human adipose tissue. Journal of Lipid Research 51:7, pages 1991-2000.
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James W Albers, David H Garabrant, Stanley Berent & Rudy J Richardson. (2009) Paraoxonase status and plasma butyrylcholinesterase activity in chlorpyrifos manufacturing workers. Journal of Exposure Science & Environmental Epidemiology 20:1, pages 79-89.
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Philip W. Connelly, Bernard Zinman, Graham F. Maguire, Mary Mamakeesick, Stewart B. Harris, Robert A. Hegele, Ravi Retnakaran & Anthony J.G. Hanley. (2009) Association of the novel cardiovascular risk factors paraoxonase 1 and cystatin C in type 2 diabetes. Journal of Lipid Research 50:6, pages 1216-1222.
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Byoung-Soo Shin. (2009) Paraoxonase Gene Polymorphism in South-western Korean Population. Journal of Korean Medical Science 24:4, pages 561.
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B.-S. Shin, S.-Y. Oh, Y.-S. Kim & K.-W. Kim. (2008) The paraoxonase gene polymorphism in stroke patients and lipid profile. Acta Neurologica Scandinavica 117:4, pages 237-243.
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Hong-Wei Xu, Ning Yuan, Zhen Zhao, Le Zhang, Jian Xia, Kai-Min Zeng, Bo Xiao, Xiao-Su Yang & Bei-Sha Tang. (2008) Study of the Relationship between Gene Polymorphisms of Paraoxonase 2 and Stroke in a Chinese Population. Cerebrovascular Diseases 25:1-2, pages 87-94.
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N. Bourquard, D.M. Shih, C.J. Ng, N. Villa-Garcia, K. Nakamura, D.A. Stoltz, E. Ozer, V. Grijalva, N. Rozengurt, S.Y. Hama, J. Zabner, M. Navab, A.M. Fogelman & S.T. Reddy. 2008. The Paraoxonases: Their Role in Disease Development and Xenobiotic Metabolism. The Paraoxonases: Their Role in Disease Development and Xenobiotic Metabolism 103 128 .
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Ritu Sharma, Balwant Singh & Mridula Mahajan. (2009) PON1 Activity is Inversely Related to LDL ApoB Carbonyl Content in Patients with Coronary Artery Disease. The Kaohsiung Journal of Medical Sciences 23:5, pages 225-231.
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Ying Zhang, Fang Zheng, Hansong Du, Joan C. Krepinsky, Julien A.G. Segbo & Xin Zhou. (2006) Detecting the polymorphisms of paraoxonase (PON) cluster in Chinese Han population based on a rapid method. Clinica Chimica Acta 365:1-2, pages 98-103.
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Yasemin D. Ak?ay, Ferhan G. Sagin, Fatih ?enda?Kemal Oztekin & Eser Y. Sozmen. (2006) Effects of estrogen-only therapy on LDL oxidation in women with hysterectomy: Does paraoxonase genotype play a role?. Maturitas 53:3, pages 325-332.
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B. MACKNESS, P. Mcelduff & M. I. MACKNESS. (2005) The paraoxonase-2-310 polymorphism is associated with the presence of microvascular complications in diabetes mellitus. Journal of Internal Medicine 258:4, pages 363-368.
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Mariette Verlaan, Erik G A Harbers, Akos Pap, Jan B M J Jansen, Wilbert H M Peters & Joost P H Drenth. (2005) Paraoxonase 1-192Q Allele is a Risk Factor for Idiopathic Chronic Pancreatitis. Molecular Diagnosis 9:1, pages 9-15.
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Michael Aviram & Mira Rosenblat. (2004) Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development. Free Radical Biology and Medicine 37:9, pages 1304-1316.
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Ken C. Chiu, Lee-Ming Chuang, Audrey Chu, Jeffrey Lu, Jun Hu & Sandra Fernando. (2004) Association of Paraoxonase 1 Polymorphism With Beta-Cell Function. Pancreas 28:4, pages e96-e103.
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T Dantoine, J Debord, L Merle & J.-P Charmes. (2003) De l’intoxication par les composés organophosphorés à l’athérosclérose : rôles de la paraoxonase 1. La Revue de Médecine Interne 24:7, pages 436-442.
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Kenichi Kuremoto, Yoshiro Watanabe, Hirotoshi Ohmura, Kazunori Shimada, Hiroshi Mokuno & Hiroyuki Daida. (2003) R/R Genotype of Human Paraoxonase(PON1) is More Protective against Lipoprotein Oxidation and Coronary Artery Disease in Japanese Subjects.. Journal of Atherosclerosis and Thrombosis 10:2, pages 85-92.
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