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Original Article

Suppression of Experimental Allergic Encephalomyelitis by Interferon

Pages 1-7 | Published online: 07 Jul 2009

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C. L. Yasuda, A. Al-sabbagh, E. C. Oliveira, B. M. Diaz-Bardales, C. A. A. Garcia & L. M-B Santos. (1999) Interferon β Modulates Experimental Autoimmune Encephalomyelitis by Altering the Pattern of Cytokine Secretion. Immunological Investigations 28:2-3, pages 115-126.
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Annabelle A. Okada, Hiroshi Keino, Tohru Fukai, Jun-ichi Sakai, Masahiko Usui & Junichiro Mizuguchi. (1998) Effect of type I interferon on experimental autoimmune uveoretinitis in rats. Ocular Immunology and Inflammation 6:4, pages 215-226.
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Francine J. Vriesendorp, Robyn E. Fly, Mohammad Khan, Miguel A. Pappolla & Staley A. Brod. (1996) Oral Administration of Type I Interferon Modulates the Course of Experimental Allergic Neuritis. Autoimmunity 24:3, pages 157-165.
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Jelena Veljić, Dragan Maric & Branislav D. Janković. (1991) Changes of experimental allergic encephalomyelitis by methionine-enkephalin injected into lateral ventricles of the rat brain. International Journal of Neuroscience 59:1-3, pages 81-89.
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Articles from other publishers (50)

Jin Wang, Kellie Brown, Caroline Danehy, Emmanuel Mérigeon, Stephen Goralski, Samuel Rice, Kwame Torgbe, Fridtjof Thomas, David Block, Henrik Olsen, Scott E. Strome & Elizabeth A. Fitzpatrick. (2023) Fc multimers effectively treat murine models of multiple sclerosis. Frontiers in Immunology 14.
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Maedeh Radandish, Parvin Khalilian & Nafiseh Esmaeil. (2021) The Role of Distinct Subsets of Macrophages in the Pathogenesis of MS and the Impact of Different Therapeutic Agents on These Populations. Frontiers in Immunology 12.
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Insha Zahoor, Bin Rui, Junaid Khan, Indrani Datta & Shailendra Giri. (2021) An emerging potential of metabolomics in multiple sclerosis: a comprehensive overview. Cellular and Molecular Life Sciences 78:7, pages 3181-3203.
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Kelly L. Monaghan & Edwin C.K. Wan. (2020) The Role of Granulocyte-Macrophage Colony-Stimulating Factor in Murine Models of Multiple Sclerosis. Cells 9:3, pages 611.
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J. Singh, M. Cerghet, L. M. Poisson, I. Datta, K. Labuzek, H. Suhail, R. Rattan & Shailendra Giri. (2018) Urinary and Plasma Metabolomics Identify the Distinct Metabolic Profile of Disease State in Chronic Mouse Model of Multiple Sclerosis. Journal of Neuroimmune Pharmacology 14:2, pages 241-250.
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Sneham Tiwari, Jessica Lapierre, Chet Raj Ojha, Kyle Martins, Tiyash Parira, Rajib Kumar Dutta, Allen Caobi, Luis Garbinski, Yasemin Ceyhan, Maria Esteban-Lopez & Nazira El-Hage. (2018) Signaling pathways and therapeutic perspectives related to environmental factors associated with multiple sclerosis. Journal of Neuroscience Research 96:12, pages 1831-1846.
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Simon Glatigny & Estelle Bettelli. (2018) Experimental Autoimmune Encephalomyelitis (EAE) as Animal Models of Multiple Sclerosis (MS). Cold Spring Harbor Perspectives in Medicine 8:11, pages a028977.
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Duncheng Wang, Debjani Ghosh, S. M. Touhidul Islam, Cody D. Moorman, Ashton E. Thomason, Daniel S. Wilkinson & Mark D. Mannie. (2016) IFN-β Facilitates Neuroantigen-Dependent Induction of CD25+ FOXP3+ Regulatory T Cells That Suppress Experimental Autoimmune Encephalomyelitis. The Journal of Immunology 197:8, pages 2992-3007.
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Trevor Owens, Reza Khorooshi, Agnieszka Wlodarczyk & Nasrin Asgari. (2014) Interferons in the central nervous system: A few instruments play many tunes. Glia 62:3, pages 339-355.
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Daisuke Kudo, Kazuko Uno, Tetsuji Aoyagi, Yukiko Akahori, Keiko Ishii, Emi Kanno, Ryoko Maruyama, Shigeki Kushimoto, Mitsuo Kaku & Kazuyoshi Kawakami. (2013) Low-dose Interferon-α Treatment Improves Survival and Inflammatory Responses in a Mouse Model of Fulminant Acute Respiratory Distress Syndrome. Inflammation 36:4, pages 812-820.
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Dimitrios Karussis. (2013) Immunotherapy of Multiple Sclerosis. BioDrugs 27:2, pages 113-148.
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Robert C. Axtell & Chander Raman. (2012) Janus-like effects of type I interferon in autoimmune diseases. Immunological Reviews 248:1, pages 23-35.
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Cris S Constantinescu, Nasr Farooqi, Kate O'Brien & Bruno Gran. (2011) Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS). British Journal of Pharmacology 164:4, pages 1079-1106.
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Nasr Farooqi, Bruno Gran & Cris S. Constantinescu. (2010) Are current disease-modifying therapeutics in multiple sclerosis justified on the basis of studies in experimental autoimmune encephalomyelitis?. Journal of Neurochemistry 115:4, pages 829-844.
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Mark D. Mannie, Derek J. Abbott & J. Lori Blanchfield. (2009) Experimental Autoimmune Encephalomyelitis in Lewis rats: IFN-β Acts As a Tolerogenic Adjuvant for Induction of Neuroantigen-Dependent Tolerance. The Journal of Immunology 182:9, pages 5331-5341.
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Alfons Billiau. (2007) Interferons: The pathways of discovery. Journal of Clinical Virology 39:4, pages 241-265.
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Alfons Billiau. (2006) Anti-inflammatory properties of Type I interferons. Antiviral Research 71:2-3, pages 108-116.
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Hubertine Heremans & Alfons Billiau. 2005. Experimental Models of Multiple Sclerosis. Experimental Models of Multiple Sclerosis 313 342 .
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Lawrence Jacobs, Richard Rudick & Jack Simon. (2000) Extended observations on MS patients treated with IM interferon-β1a (Avonex™): implications for modern MS trials and therapeutics. Journal of Neuroimmunology 107:2, pages 167-173.
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Staley A. Brod, J. William Lindsey & Jerry S. Wolinsky. (2000) Combination therapy with glatiramer acetate (copolymer-1) and a type I interferon (IFN-?) does not improve experimental autoimmune encephalomyelitis. Annals of Neurology 47:1, pages 127-131.
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Joon H. Uhm, Nora P. Dooley, Olaf Stuve, Gordon S. Francis, Pierre Duquette, Jack P. Antel & Voon Wee Yong. (1999) Migratory behavior of lymphocytes isolated from multiple sclerosis patients: Effects of interferon ?-1b therapy. Annals of Neurology 46:3, pages 319-324.
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W.B Cowden, F.A Cullen, M.A Staykova & D.O Willenborg. (1998) Nitric oxide is a potential down-regulating molecule in autoimmune disease: inhibition of nitric oxide production renders PVG rats highly susceptible to EAE. Journal of Neuroimmunology 88:1-2, pages 1-8.
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Peter H van der Meide, Miranda C.D.C de Labie, Sigrid R Ruuls, Reno J Groenestein, Carolien A.D Botman, Tomas Olsson & Christine D Dijkstra. (1998) Discontinuation of treatment with IFN-β leads to exacerbation of experimental autoimmune encephalomyelitis in Lewis rats. Rapid reversal of the antiproliferative activity of IFN-β and excessive expansion of autoreactive T cells as disease promoting mechanisms. Journal of Neuroimmunology 84:1, pages 14-23.
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Nachum Dafny. (1998) Is interferon-α a neuromodulator?. Brain Research Reviews 26:1, pages 1-15.
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Sigrid R Ruuls & Jonathon D Sedgwick. (1998) Cytokine-directed therapies in multiple sclerosis and experimental autoimmune encephalomyelitis. Immunology and Cell Biology 76:1, pages 65-73.
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Olaf Stuve, Sophie Chabot, Sonia S Jung, Gary Williams & Voon Wee Yong. (1997) Chemokine-enhanced migration of human peripheral blood mononuclear cells is antagonized by interferon beta-1b through an effect on matrix metalloproteinase-9. Journal of Neuroimmunology 80:1-2, pages 38-46.
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PATRICIA A. NELSON, YEVGENYA AKSELBAND, SUSAN M. DEARBORN, AHMAD AL-SABBAGH, Z. JANE TIAN, PATRICIA A. GONNELLA, SCOTT S. ZAMVIL, YOUHAI CHEN & HOWARD L. WEINER. (1996) Effect of Oral Beta Interferon on Subsequent Immune Responsiveness. Annals of the New York Academy of Sciences 778:1, pages 145-155.
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Barry G. W. Arnason, Amit Dayal, Zhi Xiang Qu, Mark A. Jensen, Kursad Gen� & Anthony T. Reder. (1996) Mechanisms of action of interferon-? in multiple sclerosis. Springer Seminars in Immunopathology 18:1, pages 125-148.
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