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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 41, 2012 - Issue 1
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Research Article

Role of Treg Cells and TGF-β1 in Patients with Systemic Lupus Erythematosus: A Possible Relation with Lupus Nephritis

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Pages 15-27 | Published online: 12 May 2011

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Read on this site (8)

Vikas Kailashiya, Usha Singh, Ranjan Rana, Nand Kumar Singh, Debabrata Dash & Jyotsna Kailashiya. (2019) Regulatory T Cells and Their Association with Serum Markers and Symptoms in Systemic Lupus Erythematosus and Rheumatoid Arthritis. Immunological Investigations 48:1, pages 64-78.
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Parisa Zafari, Kheirollah Yari, Shayan Mostafaei, Nasrin Iranshahi, Shirin Assar, Adel Fekri & Mahdi Taghadosi. (2018) Analysis of Helios gene expression and Foxp3 TSDR methylation in the newly diagnosed Rheumatoid Arthritis patients. Immunological Investigations 47:6, pages 632-642.
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Mohsen Ghoryani, Maryam Sahebari, Mahmoud Mahmoudi, Nafise Abdollahi, Hadi Reihani, Shahrzad Zamani Taghizadeh Rabe, Nafise Tabasi & Maryam Rastin. (2016) Immunomodulatory vitamin D effects on regulatory T-cells and cytokines in an in vitro study on patients with systemic lupus erythematosus. Food and Agricultural Immunology 27:3, pages 377-387.
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Mingke Zheng, Chen Xing, He Xiao, Ning Ma, Xiaoqian Wang, Gencheng Han, Guojiang Chen, Chunmei Hou, Beifen Shen, Yan Li & Renxi Wang. (2014) Interaction of CD5 and CD72 is involved in regulatory T and B cell homeostasis. Immunological Investigations 43:7, pages 705-716.
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Wei Zhu, Jianbo Yu, Ying Nie, XueKui Shi, Yang Liu, Fujuan Li & Xiao-li Zhang. (2014) Disequilibrium of M1 and M2 Macrophages Correlates with the Development of Experimental Inflammatory Bowel Diseases. Immunological Investigations 43:7, pages 638-652.
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Qi Liang, Yanmei Jiao, Tong Zhang, Rui Wang, Wei Li, Hongwei Zhang, Xiaojie Huang, Zhong Tang & Hao Wu. (2013) Double Negative (DN) [CD3(+)CD4(−)CD8(−)] T cells correlate with disease progression during HIV infection. Immunological Investigations 42:5, pages 431-437.
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Claudia E. Ávalos-Martínez, Juan Carlos Rodríguez-Alba, Laura Berrón-Ruiz, Hector Romero-Ramírez, Leopoldo Santos-Argumedo, Luis Antonio Jiménez-Zamudio, Maria Lilia Domínguez-López, Armando Vega-López & Ethel García-Latorre. (2013) Measurement of Suppressor Activity of T CD4+CD25+ T Reg Cells Using Bromodeoxyuridine Incorporation Assay. Immunological Investigations 42:4, pages 369-381.
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Ji-Min Zhu, Bai-Kun Li, Gui-Mei Chen, Chen-Chen Feng, Han Cen, Yin-Guang Fan, Bin Wang, Hai-Feng Pan & Dong-Qing Ye. (2013) CTLA-4 -1722T/C Polymorphism and Systemic Lupus Erythematosus Susceptibility: A Meta-analysis Involving Ten Separate Studies. Immunological Investigations 42:2, pages 91-105.
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Atefeh Alaei, Mahmoud Mahmoudi, Maryam Sahebari, Zohreh Vahidi, Nafiseh Tabasi & Maryam Rastin. (2023) The effects of Lactobacillus delbrueckii and Lactobacillus rhamnosus on cytokines and their related molecules: An ex vivo study on patients with systemic lupus erythematosus. Archives of Rheumatology 38:4, pages 642-652.
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Jingjing Wang, Mengyue Zhu, Chenfeng Jiao, Xiaodong Xu, Feng Xu, Dandan Liang, Zhengzhao Liu, Yinghua Chen & Haitao Zhang. (2023) Association of regulatory T cells with renal outcomes in patients with proliferative lupus nephritis. Lupus 32:11, pages 1237-1244.
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Leila Amini, Jaspal Kaeda, Enrico Fritsche, Andy Roemhild, Daniel Kaiser & Petra Reinke. (2023) Clinical adoptive regulatory T Cell therapy: State of the art, challenges, and prospective. Frontiers in Cell and Developmental Biology 10.
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Amal H. Eissa, Abeer M. Zahran, Hussein S. El-Fishawy, Mohamed S. Tawfik & Eman M. Eltahlawy. (2023) Protective role of T regulatory (Treg) cells in systemic lupus erythematosus patients with nephritis. The Egyptian Rheumatologist 45:1, pages 61-65.
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He‐Tong Li, Sheng‐Xiao Zhang, Jia‐Qi Zhang, Ting Cheng, Yan Liu, Hong‐Qi Liu, Min Hao & Jun‐Wei Chen. (2022) A decreased number of circulating regulatory T cells is associated with adverse pregnancy outcomes in patients with systemic lupus erythematosus. Immunity, Inflammation and Disease 10:12.
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Yixi Li, Donge Tang, Lianghong Yin & Yong Dai. (2022) New insights for regulatory T cell in lupus nephritis. Autoimmunity Reviews 21:8, pages 103134.
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Margherita Sisto, Domenico Ribatti & Sabrina Lisi. (2021) Organ Fibrosis and Autoimmunity: The Role of Inflammation in TGFβ-Dependent EMT. Biomolecules 11:2, pages 310.
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Clemens Scheinecker, Lisa Göschl & Michael Bonelli. (2020) Treg cells in health and autoimmune diseases: New insights from single cell analysis. Journal of Autoimmunity 110, pages 102376.
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Lisa Göschl, Clemens Scheinecker & Michael Bonelli. (2019) Treg cells in autoimmunity: from identification to Treg-based therapies. Seminars in Immunopathology 41:3, pages 301-314.
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Y Zhu, Y Huang, B Ming, X Wu, Y Chen & L Dong. (2019) Regulatory T-cell levels in systemic lupus erythematosus patients: a meta-analysis. Lupus 28:4, pages 445-454.
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Wenli Li, Chuiwen Deng, Hanbo Yang & Guochun Wang. (2019) The Regulatory T Cell in Active Systemic Lupus Erythematosus Patients: A Systemic Review and Meta-Analysis. Frontiers in Immunology 10.
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Yu Tian, Yu‐Xiang Han, Hui‐Fang Guo, Hong‐Tao Jin, Chao Sun, Xuan Qi, Li‐Yan Ma & Shi‐Wei Bo. (2018) Retracted : Upregulated microRNA‐485 suppresses apoptosis of renal tubular epithelial cells in mice with lupus nephritis via regulating the TGF‐β‐MAPK signaling pathway by inhibiting RhoA expression . Journal of Cellular Biochemistry 119:11, pages 9154-9167.
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Sheng-Xiao Zhang, Xiao-Wen Ma, Yu-Feng Li, Na-Ling Lai, Ze-Hao Huang, Kai Fan, Cai-Hong Wang & Xiao-Feng Li. (2018) The Proportion of Regulatory T Cells in Patients with Systemic Lupus Erythematosus: A Meta-Analysis. Journal of Immunology Research 2018, pages 1-11.
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Raja Rekik, Monia Smiti Khanfir, Thara Larbi, Imen Zamali, Asma Beldi-Ferchiou, Ons Kammoun, Soumaya Marzouki, Saloua Hamzaoui, Skander Mrad, Mohamed Ridha Barbouche, Mohamed Habib Houman & Melika Ben Ahmed. (2018) Impaired TGF-β signaling in patients with active systemic lupus erythematosus is associated with an overexpression of IL-22. Cytokine 108, pages 182-189.
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Rahul Sharma & Gilbert R. Kinsey. (2018) Regulatory T cells in acute and chronic kidney diseases. American Journal of Physiology-Renal Physiology 314:5, pages F679-F698.
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Yingyi Yu, Yuanyuan Shi, Xinyi Zuo, Qi Feng, Yu Hou, Wei Tang, Yi Lu, Fan Yi, Ming Hou, Yuan Yu & Jun Peng. (2018) Progranulin facilitates the increase of platelet count in immune thrombocytopenia. Thrombosis Research 164, pages 24-31.
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D MesquitaJr.Jr., G Mastroianni Kirsztajn, M F Franco, L A Reis, S F Perazzio, F V Mesquita, V da Silva Ferreira, L E Coelho Andrade & A W Silva de Souza. (2018) CD4+ T helper cells and regulatory T cells in active lupus nephritis: an imbalance towards a predominant Th1 response?. Clinical and Experimental Immunology 191:1, pages 50-59.
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Yi Yuan, Mingyue Yang, Kuo Wang, Jing Sun, Lili Song, Xue Diao, Zhenyu Jiang, Genhong Cheng & Xiaosong Wang. (2017) Excessive activation of the TLR9/TGF-?1/PDGF-B pathway in the peripheral blood of patients with systemic lupus erythematosus. Arthritis Research & Therapy 19:1.
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Seyed-Alireza Esmaeili, Mahmoud Mahmoudi, Amir Abbas Momtazi, Amirhossein Sahebkar, Hassan Doulabi & Maryam Rastin. (2017) Tolerogenic probiotics: potential immunoregulators in Systemic Lupus Erythematosus. Journal of Cellular Physiology 232:8, pages 1994-2007.
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B Jakiela, T Iwaniec, H Plutecka, M Celinska-Lowenhoff, S Dziedzina & J Musial. (2015) Signs of impaired immunoregulation and enhanced effector T-cell responses in the primary antiphospholipid syndrome. Lupus 25:4, pages 389-398.
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Kadiombo Anastasie Tshilela, Hidekazu Ikeuchi, Takayuki Matsumoto, Takashi Kuroiwa, Noriyuki Sakurai, Toru Sakairi, Yoriaki Kaneko, Akito Maeshima, Keiju Hiromura & Yoshihisa Nojima. (2015) Glomerular cytokine expression in murine lupus nephritis. Clinical and Experimental Nephrology 20:1, pages 23-29.
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Siham Aly Metawie, Rasha M. ElRefai, Suzan Sadek ElAdle & Rasha Mohamad Hosny Shahin. (2015) Transforming growth factor-?1 in systemic lupus erythematosus patients and its relation to organ damage and disease activity. The Egyptian Rheumatologist 37:4, pages S49-S54.
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Desmond Yap & Kar Lai. (2015) Pathogenesis of Renal Disease in Systemic Lupus Erythematosus—The Role of Autoantibodies and Lymphocytes Subset Abnormalities. International Journal of Molecular Sciences 16:12, pages 7917-7931.
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Raquel Rodrigues-Díez, Sandra Rayego-Mateos, Macarena Orejudo, Luiz Stark Aroeira, Rafael Selgas, Alberto Ortiz, Jesús Egido & Marta Ruiz-Ortega. (2015) TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module of the CCN2. Mediators of Inflammation 2015, pages 1-10.
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W Chuan, W Wu-qing, Y Zhu-wen & L Zuo. (2014) Effect of nonmyeloablative unrelated fetal and neonatal murine peripheral blood mononuclear cell infusion on MRL/lpr mice. Lupus 23:10, pages 994-1005.
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Victoria Martina Trucci, Fernanda Gonçalves Salum, Maria Antonia Figueiredo & Karen Cherubini. (2013) Interrelationship of dendritic cells, type 1 interferon system, regulatory T cells and toll-like receptors and their role in lichen planus and lupus erythematosus – A literature review. Archives of Oral Biology 58:10, pages 1532-1540.
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Ding-Lei Su, Zhi-Min Lu, Min-Ning Shen, Xia Li & Ling-Yun Sun. (2012) Roles of Pro- and Anti-Inflammatory Cytokines in the Pathogenesis of SLE. Journal of Biomedicine and Biotechnology 2012, pages 1-15.
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Akiko Okamoto, Keishi Fujio, Tomohisa Okamura & Kazuhiko Yamamoto. (2011) Regulatory T-Cell-Associated Cytokines in Systemic Lupus Erythematosus. Journal of Biomedicine and Biotechnology 2011, pages 1-9.
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