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Laboratory Study

Evaluation of Efficacy of Vitamin E and N-Acetyl Cysteine in Gentamicin-Induced Nephrotoxicity in Rats

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Pages 341-347 | Received 04 Aug 2010, Accepted 27 Jan 2011, Published online: 14 Mar 2011

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Zahra Azarmehr, Najmeh Ranji, Zeinab Khazaei Koohpar & Hadi Habibollahi. (2021) The effect of N-Acetyl cysteine on the expression of Fxr (Nr1h4), LXRα (Nr1h3) and Sirt1 genes, oxidative stress, and apoptosis in the liver of rats exposed to different doses of cadmium. Molecular Biology Reports 48:3, pages 2533-2542.
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Carolina Martinez Romão, Rafael Canavel Pereira, Maria Heloisa Massola Shimizu & Luzia Naôko Shinohara Furukawa. (2019) N-acetyl-l-cysteine exacerbates kidney dysfunction caused by a chronic high-sodium diet in renal ischemia and reperfusion rats. Life Sciences 231, pages 116544.
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Egor Y. Plotnikov, Tatiana A. Pavlenko, Irina B. Pevzner, Ljubava D. Zorova, Vasily N. Manskikh, Denis N. Silachev, Gennady T. Sukhikh & Dmitry B. Zorov. (2017) The role of oxidative stress in acute renal injury of newborn rats exposed to hypoxia and endotoxin. The FEBS Journal 284:18, pages 3069-3078.
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Fatemeh Ramezani Nowrozani, Sheyda Asmarian & Hamed Yarmahmoodi. (2016) Electron microscopic evaluation of milk thistle, chicory, and vitamin E effects on gentamicin-induced nephrotoxicity in rat. Comparative Clinical Pathology 25:5, pages 1023-1028.
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Nataliya I. SkrypnykLeah J. Siskind, Sarah Faubel & Mark P. de Caestecker. (2016) Bridging translation for acute kidney injury with better preclinical modeling of human disease. American Journal of Physiology-Renal Physiology 310:10, pages F972-F984.
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Hassan Ahmadvand, Majid Tavafi, Vahideh Asadollahi, Leila Jafaripour, Forouzan Hadipour-Moradi, Reza Mohammadrezaei-Khoramabadi, Peyman Khosravi, Hadis Salehi & Ahmad Cheraghi. (2016) Protective Effect of Carvacrol on Renal Functional and Histopathological Changes in Gentamicin-Induced-Nephrotoxicity in Rats. Zahedan Journal of Research in Medical Sciences In Press:In Press.
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Pengfei Liu, Yetong Feng, Delu Dong, Xiaobo Liu, Yaoyu Chen, Yi Wang & Yulai Zhou. (2016) Enhanced renoprotective effect of IGF-1 modified human umbilical cord-derived mesenchymal stem cells on gentamicin-induced acute kidney injury. Scientific Reports 6:1.
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Rimda Wanchoo, Seyyar Khan, Jonathan E Kolitz & Kenar D Jhaveri. (2014) Carfilzomib-related acute kidney injury may be prevented by N -acetyl- l -cysteine . Journal of Oncology Pharmacy Practice 21:4, pages 313-316.
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Ankush Sardana, Sanjeev Kalra, Deepa Khanna & Pitchai Balakumar. (2014) Nephroprotective effect of catechin on gentamicin-induced experimental nephrotoxicity. Clinical and Experimental Nephrology 19:2, pages 178-184.
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Chu-Kung Chou, Yi-Chieh Li, Shih-Ming Chen, Yi-Min Shih & Jen-Ai Lee. (2015) Chitosan Prevents Gentamicin-Induced Nephrotoxicity via a Carbonyl Stress-Dependent Pathway. BioMed Research International 2015, pages 1-8.
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Amr A. Fouad, Waleed H. Albuali, Ahmed Zahran & Wafaey Gomaa. (2014) Protective effect of naringenin against gentamicin-induced nephrotoxicity in rats. Environmental Toxicology and Pharmacology 38:2, pages 420-429.
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C. G. Le Prell, C. Ojano-Dirain, E. W. Rudnick, M. A. Nelson, S. J. DeRemer, D. M. Prieskorn & J. M. Miller. (2014) Assessment of Nutrient Supplement to Reduce Gentamicin-Induced Ototoxicity. Journal of the Association for Research in Otolaryngology.
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Siddesh Jaiman, Arun Kumar Sharma, Kulwant Singh & Deepa Khanna. (2013) Signalling mechanisms involved in renal pathological changes during cisplatin-induced nephropathy. European Journal of Clinical Pharmacology 69:11, pages 1863-1874.
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Gururao Hariprasad, Manoj Kumar, Komal Rani, Punit Kaur & Alagiri Srinivasan. (2011) Aminoglycoside induced nephrotoxicity: molecular modeling studies of calreticulin-gentamicin complex. Journal of Molecular Modeling 18:6, pages 2645-2652.
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