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Laboratory Study

Protective Effect of Infliximab on Ischemia/Reperfusion-Induced Damage in Rat Kidney

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Pages 1144-1149 | Received 18 Apr 2012, Accepted 18 Jul 2010, Published online: 06 Sep 2012

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Felix Poppelaars, Mariana Gaya da Costa, Bernardo Faria, Siawosh K Eskandari, Marc A Seelen & Jeffrey Damman. (2022) Tumor Necrosis Factor-α Gene Polymorphism is Associated with Short- and Long-Term Kidney Allograft Outcomes. Journal of Inflammation Research 15, pages 2243-2254.
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Mahitab M. Nageeb, Aliaa Talaat, Samar M. Reda & Ghada A. Elsammak. (2023) Infliximab abrogates adenine-induced chronic kidney disease via modulation of the MAPK/JNK/ASK signaling pathway in rats. Naunyn-Schmiedeberg's Archives of Pharmacology.
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Hoda E. Mohamed, Mervat E. Askar, Mohamed A. Shaheen, Alaa E. Salama, Reham A. Idris & Nahla N. Younis. (2023) Infliximab substantially re‐silenced Wnt/β‐catenin signaling and ameliorated doxorubicin‐induced cardiomyopathy in rats. Journal of Biochemical and Molecular Toxicology 37:5.
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Edgar Mendieta-Condado, Elda Cristina Villaseñor-Tapia, Francisco Javier Gálvez-Gastelum, Irinea Yáñez-Sánchez, Oscar Pizano-Martínez, Alejandro Canales-Aguirre & Ana Laura Márquez-Aguirre. (2022) Effects of Etanercept on TNF-α Inhibition in Rats with Adenine-Induced Chronic Kidney Disease. BioMed Research International 2022, pages 1-8.
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Ersin Koksal, Yasemin Burcu Ustun, Sezgin Bilgin, Abdurrahman Aksoy, Yavuz Kursad Das, Murat Yarim, Fatih Ozkan, Cengiz Kaya & Burhan Dost. (2022) The effects of dexketoprofen on renal ischemia-reperfusion injury: an experimental study. Brazilian Journal of Anesthesiology (English Edition) 72:3, pages 365-371.
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Yiru Zhou, Ruihua Fan, Benson O. A. Botchway, Yong Zhang & Xuehong Liu. (2021) Infliximab Can Improve Traumatic Brain Injury by Suppressing the Tumor Necrosis Factor Alpha Pathway. Molecular Neurobiology 58:6, pages 2803-2811.
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Yasmine A Abdelhamid, Mohammed F Elyamany, Muhammad Y Al-Shorbagy & Osama A Badary. (2020) Effects of TNF-α antagonist infliximab on fructose-induced metabolic syndrome in rats. Human & Experimental Toxicology 40:5, pages 801-811.
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Nahla N. Younis, Hoda E. Mohamed, Mohamed A. Shaheen, Asmaa M. Abdelghafour & Sally K. Hammad. (2021) Inactivation of Wnt/β-catenin/renin angiotensin axis by tumor necrosis factor-alpha inhibitor, infliximab, ameliorates CKD induced in rats. Biochemical Pharmacology 185, pages 114426.
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Н.В. Андрианова, Д.Б. Зоров & Е.Ю. Плотников. (2020) Воспаление и окислительный стресс как мишени для терапии ишемического повреждения почек. Биохимия 85:12, pages 1873-1886.
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N. V. Andrianova, D. B. Zorov & E. Y. Plotnikov. (2020) Targeting Inflammation and Oxidative Stress as a Therapy for Ischemic Kidney Injury. Biochemistry (Moscow) 85:12-13, pages 1591-1602.
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Ruochen CongJushun YangJie ZhouJianhua ShiYihua ZhuJianfeng ZhuJing XiaoPing WangYing HeBosheng He. (2020) The Potential Role of Protein Tyrosine Phosphatase, Receptor Type C (CD45) in the Intestinal Ischemia–Reperfusion Injury. Journal of Computational Biology 27:8, pages 1303-1312.
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Hoda E. Mohamed, Mervat E. Asker, Mohammed M. Keshawy, Rehab A. Hasan & Yasmin K. Mahmoud. (2020) Inhibition of tumor necrosis factor-α enhanced the antifibrotic effect of empagliflozin in an animal model with renal insulin resistance. Molecular and Cellular Biochemistry 466:1-2, pages 45-54.
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Aly M. Abdelrahman, Yousuf M. Al Suleimani, Priyadarsini Manoj, Mohammed Ashique, Badreldin H. Ali & Nicole Schupp. (2019) Effect of infliximab, a tumor necrosis factor-alpha inhibitor, on doxorubicin-induced nephrotoxicity in rats. Naunyn-Schmiedeberg's Archives of Pharmacology 393:1, pages 121-130.
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Wenqing Yin, Tripti Kumar, Zongshan Lai, Xu Zeng, Hassan D. Kanaan, Wei Li & Ping L. Zhang. (2019) Kidney injury molecule-1, a sensitive and specific marker for identifying acute proximal tubular injury, can be used to predict renal functional recovery in native renal biopsies. International Urology and Nephrology 51:12, pages 2255-2265.
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Ricardo O. S. Soares, Daniele M. Losada, Maria C. Jordani, Paulo Évora & Orlando Castro-e-Silva. (2019) Ischemia/Reperfusion Injury Revisited: An Overview of the Latest Pharmacological Strategies. International Journal of Molecular Sciences 20:20, pages 5034.
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Raghda Habib, Sara A. Wahdan, Amany M. Gad & Samar S. Azab. (2019) Infliximab abrogates cadmium-induced testicular damage and spermiotoxicity via enhancement of steroidogenesis and suppression of inflammation and apoptosis mediators. Ecotoxicology and Environmental Safety 182, pages 109398.
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Makoto Kanno, Masaaki Nakayama, Wan-Jun Zhu, Yoshimitsu Hayashi & Junichiro J Kazama. (2018) Rosuvastatin pretreatment suppresses distant organ injury following unilateral renal ischemia-reperfusion in hypertensive Dahl salt-sensitive rats. Nephrology 23:11, pages 1046-1054.
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Ling Hou, Gang Chen, Biao Feng, Xu-sheng Zhang, Xiu-fen Zheng, Ying Xiang, Guang-yuan Zhao & Wei-Ping Min. (2016) Small interfering RNA targeting TNF-α gene significantly attenuates renal ischemia-reperfusion injury in mice. Journal of Huazhong University of Science and Technology [Medical Sciences] 36:5, pages 634-638.
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Yudai Nagata, Mitsuaki Fujimoto, Kimihiko Nakamura, Naohito Isoyama, Masafumi Matsumura, Koki Fujikawa, Koichi Uchiyama, Eiichi Takaki, Ryosuke Takii, Akira Nakai & Hideyasu Matsuyama. (2016) Anti-TNF-α Agent Infliximab and Splenectomy Are Protective Against Renal Ischemia-Reperfusion Injury. Transplantation 100:8, pages 1675-1682.
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Cyril Moers, Robert A. Pol & Martin H. de Borst. (2016) Tumor Necrosis Factor α Blockade to Ameliorate Renal ischemia Reperfusion Injury. Transplantation 100:8, pages 1601-1602.
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Erkan Cure, Medine Cumhur Cure, Levent Tumkaya, Yildiray Kalkan, Ibrahim Aydin, Aynur Kirbas, Arif Yilmaz, Suleyman Yuce & Ahmet Fikret Yücel. (2014) Adalimumab Ameliorates Abdominal Aorta Cross Clamping Which Induced Liver Injury in Rats. BioMed Research International 2014, pages 1-8.
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Remzi Abali, Nicel Tasdemir, Mehmet Aytac Yuksel, Savas Guzel, Meltem Oznur, Burcin Nalbantoglu & Ufuk Goker Tasdemir. (2013) Protective effect of infliximab on ischemia/reperfusion injury in a rat ovary model: biochemical and histopathologic evaluation. European Journal of Obstetrics & Gynecology and Reproductive Biology 171:2, pages 353-357.
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Vivek R. Yadav, Kaustuv Sahoo, Pamela R. Roberts & Vibhudutta Awasthi. (2013) Pharmacologic Suppression of Inflammation by a Diphenyldifluoroketone, EF24, in a Rat Model of Fixed-Volume Hemorrhage Improves Survival. Journal of Pharmacology and Experimental Therapeutics 347:2, pages 346-356.
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O. Sengul, I. Ferah, B. Polat, Z. Halici, Y. Bayir, M. Yilmaz, N. Kilic & O.N. Keles. (2013) Blockade of endothelin receptors with bosentan limits ischaemia/reperfusion-induced injury in rat ovaries. European Journal of Obstetrics & Gynecology and Reproductive Biology 170:2, pages 458-463.
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Ramazan AltintasAlaadin PolatNigar VardiFatih OguzAli BeyturMustafa SagirAzibe YildizHakan Parlakpinar. (2013) The Protective Effects of Apocynin on Kidney Damage Caused by Renal Ischemia/Reperfusion. Journal of Endourology 27:5, pages 617-624.
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