8,755
Views
128
CrossRef citations to date
0
Altmetric
Brief Report

Proton pump inhibitors linked to hypomagnesemia: a systematic review and meta-analysis of observational studies

, , , , , , , & show all
Pages 1237-1241 | Received 01 Feb 2015, Accepted 13 May 2015, Published online: 25 Jun 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Farwa Jafri, Zachary L. Taylor, Daniel Gonzalez & Valentina Shakhnovich. (2023) Effects of obesity on the pharmacology of proton pump inhibitors: current understanding and future implications for patient care and research. Expert Opinion on Drug Metabolism & Toxicology 19:1, pages 1-11.
Read now
Yingsi Zeng, Lingling Liu, Liya Zhu, Xiaojiang Zhan, Fenfen Peng, Xiaoran Feng, Qian Zhou, Yujing Zhang, Zebin Wang, Jianbo Liang, Jiao Li & Yueqiang Wen. (2022) Proton pump inhibitor usage is associated with higher all-cause mortality and CV events in peritoneal dialysis patients. Renal Failure 44:1, pages 398-405.
Read now
Steven G Chrysant & George S Chrysant. (2020) Adverse cardiovascular and blood pressure effects of drug-induced hypomagnesemia. Expert Opinion on Drug Safety 19:1, pages 59-67.
Read now
Steven G. Chrysant. (2019) Proton pump inhibitor-induced hypomagnesemia complicated with serious cardiac arrhythmias. Expert Review of Cardiovascular Therapy 17:5, pages 345-351.
Read now
Zhuo Ma, Caixia Zhang, Xiangli Cui & Lihong Liu. (2019) Comparison of three criteria for potentially inappropriate medications in Chinese older adults. Clinical Interventions in Aging 14, pages 65-72.
Read now
Tibor Fülöp. (2019) Greetings to the readers. Renal Failure 41:1, pages 69-71.
Read now
Nihal El Rouby, John J. Lima & Julie A. Johnson. (2018) Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine. Expert Opinion on Drug Metabolism & Toxicology 14:4, pages 447-460.
Read now
Wisit Cheungpasitporn, Charat Thongprayoon, Tasma Harindhanavudhi, Peter J. Edmonds & Stephen B. Erickson. (2016) Hypomagnesemia linked to new-onset diabetes mellitus after kidney transplantation: A systematic review and meta-analysis. Endocrine Research 41:2, pages 142-147.
Read now

Articles from other publishers (120)

Jing Miao & Sandra M Herrmann. (2023) Immune checkpoint inhibitors and their interaction with proton pump inhibitors–related interstitial nephritis. Clinical Kidney Journal 16:11, pages 1834-1844.
Crossref
Wen Liu, Jia Wang, Miao Wang, Miaomiao Wang & Ming Liu. (2023) Association of proton pump inhibitor use with risk of kidney stones: an analysis of cross-sectional data from the US National Health and Nutrition Examination Survey (2007–2018). BMJ Open 13:10, pages e075136.
Crossref
Katsuhiko Ohori, Toshiyuki Yano, Satoshi Katano, Ryohei Nagaoka, Ryo Numazawa, Kotaro Yamano, Yusuke Fujisawa, Hidemichi Kouzu, Masayuki Koyama, Nobutaka Nagano, Takefumi Fujito, Ryo Nishikawa, Wataru Ohwada & Masato Furuhashi. (2023) Independent Association Between Use of Proton Pump Inhibitors and Muscle Wasting in Patients with Heart Failure: A Single-Center, Ambispective, Observational Study. Drugs & Aging 40:8, pages 731-739.
Crossref
Huan-Lin Chen, Wei-Yi Lei, Jen-Hung Wang, Ming-Jong Bair & Chien-Lin Chen. (2023) Proton pump inhibitor use and the risk for Parkinson’s disease: A nationwide population-based study in Taiwan. Medicine 102:19, pages e33711.
Crossref
Giammarco Baiardi, Giulia Calvini, Serena Panarello, Chiara Fioravanti, Manuela Stella, Antonietta Martelli, Giancarlo Antonucci & Francesca Mattioli. (2023) Prescriptive Appropriateness: Inhospital Adherence to Proton Pump Inhibitors Deprescription Flow Chart. Pharmaceuticals 16:5, pages 635.
Crossref
Giuseppe Losurdo, Natale Lino Bruno Caccavo, Giuseppe Indellicati, Francesca Celiberto, Enzo Ierardi, Michele Barone & Alfredo Di Leo. (2023) Effect of Long-Term Proton Pump Inhibitor Use on Blood Vitamins and Minerals: A Primary Care Setting Study. Journal of Clinical Medicine 12:8, pages 2910.
Crossref
Ákos Géza Pethő, Mihály Tapolyai, Maria Browne & Tibor Fülöp. (2023) Hypomagnesemia as a Risk Factor and Accelerator for Vascular Aging in Diabetes Mellitus and Chronic Kidney Disease. Metabolites 13:2, pages 306.
Crossref
Sherry Seah, Yen Kheng Tan, Kevin Teh, Wann Jia Loh, Pei Ting Tan, Leng Chuan Goh, Roy Debajyoti Malakar, Tar Choon Aw, Chin Shern Lau, Trishpal Dhalliwal, Swee Leng Kui, Jia Wen Kam, Joan Khoo, Tunn Lin Tay, Eberta Tan, Vanessa Au, Shui Boon Soh, Meifen Zhang, Thomas F. King, Linsey Gani & Troy H. Puar. (2023) Proton-pump inhibitor use amongst patients with severe hypomagnesemia. Frontiers in Pharmacology 14.
Crossref
Naina Mohamed Pakkir Maideen. (2023) Adverse Effects Associated with Long-Term Use of Proton Pump Inhibitors. Chonnam Medical Journal 59:2, pages 115.
Crossref
Ali F. Altebainawi, Lulwa A. Alfaraj, Amjad A. Alharbi, Fadwa F. Alkhuraisi & Thamir M. Alshammari. (2023) Association between proton pump inhibitors and rhabdomyolysis risk: a post-marketing surveillance using FDA adverse event reporting system (FAERS) database. Therapeutic Advances in Drug Safety 14, pages 204209862311540.
Crossref
Mehtap Ozkahraman Kırık & Berna Uslu Coskun. 2023. Airway diseases. Airway diseases 1 27 .
Jung-yeon Kwon, Sang-hyun An & Kyung-hwan Kong. (2022) Inhibitory Effects of Dansam and Dansam-eum on Reflux Esophagitis and Migration of Cancer Cells. The Journal of Internal Korean Medicine 43:6, pages 1162-1185.
Crossref
Wei Cheng, Linlin Ma & Zui Pan. (2022) Editorial: Ion channels & homeostasis of ions in cancer cell fate. Frontiers in Oncology 12.
Crossref
Pedro Fong, Sut Tong Chan, Pui Nap Lei, Hao Ian Cheong, I Man Cheong & Weng Lam Hoe. (2022) Association of suicidal ideation and depression with the use of proton pump inhibitors in adults: a cross-sectional study. Scientific Reports 12:1.
Crossref
Marco Bonilla, Biruh T. Workeneh & Nupur N. Uppal. (2022) Hypomagnesemia in Patients With Cancer: The Forgotten Ion. Seminars in Nephrology 42:6, pages 151347.
Crossref
So Young Kim, Dae Myoung Yoo, Woo Jin Bang & Hyo Geun Choi. (2022) Association between Urolithiasis and History Proton Pump Inhibitor Medication: A Nested Case-Control Study. Journal of Clinical Medicine 11:19, pages 5693.
Crossref
Eric Lespessailles & Hechmi Toumi. (2022) Proton Pump Inhibitors and Bone Health: An Update Narrative Review. International Journal of Molecular Sciences 23:18, pages 10733.
Crossref
Samantha Duxbury, Emily Sorah & M. Katherine Tolbert. (2022) Evaluation of proton pump inhibitor administration in hospitalized dogs in a tertiary referral hospital. Journal of Veterinary Internal Medicine 36:5, pages 1622-1627.
Crossref
Abdullah M. Al Alawi, Thomas Berhane, Sandawana W. Majoni & Henrik Falhammar. (2022) Characteristics and health outcomes of patients hospitalised with hypomagnesaemia: a retrospective study from a single centre in the Northern Territory of Australia. Internal Medicine Journal 52:9, pages 1544-1553.
Crossref
Nattida Kampuang & Narongrit Thongon. (2022) Mass spectrometric analysis of TRPM6 and TRPM7 from small intestine of omeprazole-induced hypomagnesemic rats. Frontiers in Oncology 12.
Crossref
Juntao Xie, Qingui Chen & Dejian He. (2022) Pre-existing Proton Pump Inhibitor Treatment and Short-Term Prognosis of Acute Myocardial Infarction Patients. Frontiers in Cardiovascular Medicine 9.
Crossref
Łukasz Lassmann, Matteo Pollis, Agata Żółtowska & Daniele Manfredini. (2022) Gut Bless Your Pain—Roles of the Gut Microbiota, Sleep, and Melatonin in Chronic Orofacial Pain and Depression. Biomedicines 10:7, pages 1528.
Crossref
Simon Cadiou, Antonia Le Gruyer, Baptiste Giguet, François Robin, Morgane Milin, Xavier Guennoc, Pascal Guggenbuhl & Marine De Saint-Riquier. (2021) Calcium pyrophosphate deposition (CPPD) in a liver transplant patient: are hypomagnesemia, tacrolimus or both guilty? A case-based literature review. Rheumatology International 42:6, pages 1105-1112.
Crossref
Onur Tasci & Ezgi Kiran Tasci. (2022) Does the use of proton pump inhibitors in children affect ventricular repolarisation parameters?. Cardiology in the Young, pages 1-5.
Crossref
C. Zeng, T. Neogi, A.T. Chan, J. Wei, D. Misra, N. Lu, H.K. Choi, G. Lei & Y. Zhang. (2022) Proton pump inhibitor therapy and risk of knee replacement surgery: a general population-based cohort study. Osteoarthritis and Cartilage 30:4, pages 559-569.
Crossref
Bando TY, di Pace LS, Lapa M & Chehter EZ. (2022) Proton pump inhibitors: Are they safe?. Gastroenterology & Hepatology: Open Access 13:2, pages 34-47.
Crossref
Karen Clarke, Nicole Adler, Deepak Agrawal, Dimpal Bhakta, Suchita Shah Sata, Sarguni Singh, Arjun Gupta, Amit Pahwa, Emily Pherson, Alexander Sun, Frank Volpicelli & Hyung J. Cho. (2022) Indications for the Use of Proton Pump Inhibitors for Stress Ulcer Prophylaxis and Peptic Ulcer Bleeding in Hospitalized Patients. The American Journal of Medicine 135:3, pages 313-317.
Crossref
Jean-Luc Raoul, Julien Edeline, Victor Simmet, Camille Moreau-Bachelard, Marine Gilabert & Jean-Sébastien Frénel. (2022) Long-Term Use of Proton Pump Inhibitors in Cancer Patients: An Opinion Paper. Cancers 14:5, pages 1156.
Crossref
I.B. Zabolotskikh, A.A. Belkin, A.V. Butrov, E.S. Gorobec, E.V. Grigoriev, A.N. Kuzovlev, K.M. Lebedinskii, A.Yu. Lubnin, A.E. Muronov, A.M. Ovezov, A.M. Ovechkin, R.V. Shadrin & A.V. Shchegolev. (2022) Perioperative management of patients with concomitant alcohol dependence. Guidelines. Anesteziologiya i reanimatologiya:4, pages 5.
Crossref
Philip O. Katz, Kerry B. Dunbar, Felice H. Schnoll-Sussman, Katarina B. Greer, Rena Yadlapati & Stuart Jon Spechler. (2022) ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease. American Journal of Gastroenterology 117:1, pages 27-56.
Crossref
Anjan Dhar, Frances Maw, Helen Jane Dallal & Stephen Attwood. (2022) Side effects of drug treatments for gastro-oesophageal reflux disease: current controversies. Frontline Gastroenterology 13:1, pages 45-49.
Crossref
Sang Hyun Ahn, Il Shin Choi & Ki Bong Kim. (2021) Regulation of Gastric Acid Secretion of Liriope platyphylla Extract in Gastroesophageal Reflux Disease. Journal of Korean Medicine 42:4, pages 150-163.
Crossref
Jackson S. Musuuza, Emily Fong, Paul Lata, Katie Willenborg, Mary Jo Knobloch, Margaret J. Hoernke, Andrew R. Spiel, Jessica S. Tischendorf, Katie J. Suda & Nasia Safdar. (2021) Feasibility of a pharmacy-led intervention to de-implement non-guideline-concordant proton pump inhibitor use. Implementation Science Communications 2:1.
Crossref
Charat Thongprayoon, Janina Paula T. Sy-Go, Voravech Nissaisorakarn, Carissa Y. Dumancas, Mira T. Keddis, Andrea G. Kattah, Pattharawin Pattharanitima, Saraschandra Vallabhajosyula, Michael A. Mao, Fawad Qureshi, Vesna D. Garovic, John J. Dillon, Stephen B. Erickson & Wisit Cheungpasitporn. (2021) Machine Learning Consensus Clustering Approach for Hospitalized Patients with Dysmagnesemia. Diagnostics 11:11, pages 2119.
Crossref
Michael S. DanielsBrian I. ParkDiane L. McKay. (2021) Adverse Effects of Medications on Micronutrient Status: From Evidence to Guidelines. Annual Review of Nutrition 41:1, pages 411-431.
Crossref
Annalise M. Panthofer, Beini Lyu, Brad C. Astor, Tripti Singh, Fahad Aziz, Didier Mandelbrot, Sandesh Parajuli, Maha Mohamed, Arjang Djamali & Neetika Garg. (2021) Post‐kidney transplant serum magnesium exhibits a U‐shaped association with subsequent mortality: an observational cohort study. Transplant International 34:10, pages 1853-1861.
Crossref
Elizabeth J. Bell, Suzette J. Bielinski, Jennifer L. St. Sauver, Lin Y. Chen, Mary R. Rooney, Nicholas B. Larson, Paul Y. Takahashi & Aaron R. Folsom. (2021) Association of Proton Pump Inhibitors With Higher Risk of Cardiovascular Disease and Heart Failure. Mayo Clinic Proceedings 96:10, pages 2540-2549.
Crossref
Mary R. Rooney, Elizabeth J. Bell, Alvaro Alonso, James S. Pankow, Ryan T. Demmer, Kyle D. Rudser, Lin Y. Chen & Pamela L. Lutsey. (2021) Proton Pump Inhibitor Use, Hypomagnesemia and Risk of Cardiovascular Diseases. Journal of Clinical Gastroenterology 55:8, pages 677-683.
Crossref
Francesco Francini, Laura Gobbi, Verdiana Ravarotto, Silvia Toniazzo, Federico Nalesso, Paolo Spinella & Lorenzo A Calò. (2021) The Dietary Approach to the Treatment of the Rare Genetic Tubulopathies Gitelman’s and Bartter’s Syndromes. Nutrients 13:9, pages 2960.
Crossref
Juan Luo, Jie Hu, Meiling Zhang, Yue Zhang, Jiashu Wu, Jinjun Cheng, Huihua Qu, Hui Kong & Yan Zhao. (2021) Gastroprotective effects of Nelumbinis Rhizomatis Nodus- derived carbon dots on ethanol-induced gastric ulcers in rats . Nanomedicine 16:19, pages 1657-1671.
Crossref
Karen Clarke, Nicole Adler, Dimpal Bhakta, Suchita Shah Sata, Sarguni Singh, Arjun Gupta, Amit Pahwa, Emily Pherson, Alexander Sun, Frank Volpicelli & Hyung J Cho. (2021) Reducing Overuse of Proton Pump Inhibitors for Stress Ulcer Prophylaxis and Nonvariceal Gastrointestinal Bleeding in the Hospital: A Narrative Review and Implementation Guide. Journal of Hospital Medicine 16:7.
Crossref
Elizabeth M. Salvo, Nicole C. Ferko, Sarah B. Cash, Ailish Gonzalez & Peter J. Kahrilas. (2021) Umbrella review of 42 systematic reviews with meta‐analyses: the safety of proton pump inhibitors. Alimentary Pharmacology & Therapeutics 54:2, pages 129-143.
Crossref
Eiji Kose, Hidetaka Wakabayashi & Nobuhiro Yasuno. (2021) Polypharmacy and Malnutrition Management of Elderly Perioperative Patients with Cancer: A Systematic Review. Nutrients 13:6, pages 1961.
Crossref
Peter Burckhardt. (2021) Hypokalzämie, Hypophosphatämie und HypomagnesiämieHypocalcémie. hypomagnésiémie et hypophosphatémie. Journal für Gynäkologische Endokrinologie/Schweiz 24:2, pages 69-75.
Crossref
Geoffroy Desbuissons & Lucile Mercadal. (2020) Use of proton pump inhibitors in dialysis patients: a double-edged sword?. Journal of Nephrology 34:3, pages 661-672.
Crossref
Florence van Hunsel, Laura Peters, Helga Gardarsdottir & Agnes Kant. (2021) Assessing the Impact on Health of Pharmacovigilance Activities: Example of Four Safety Signals. Drug Safety 44:5, pages 589-600.
Crossref
Delfina Ana Recart, Augusto Ferraris, Carla Ines Petriglieri, Marina Alonso Serena, Maria Belen Bonella & Maria Lourdes Posadas-Martinez. (2020) Prevalence and risk factors of long-term proton pump inhibitors-associated hypomagnesemia: a cross-sectional study in hospitalized patients. Internal and Emergency Medicine 16:3, pages 711-717.
Crossref
Marcel Yibirin, Diana De Oliveira, Roberto Valera, Andrea E Plitt & Sophia Lutgen. (2021) Adverse Effects Associated with Proton Pump Inhibitor Use. Cureus.
Crossref
Hashm Albarki, Amy Pun & Paul M. Paddle. (2020) What is the truth about proton pump inhibitors?. Current Opinion in Otolaryngology & Head & Neck Surgery 28:6, pages 376-384.
Crossref
Madhav Desai, Venkat Nutalapati, Sachin Srinivasan, Jihan Fathallah, Chandra Dasari, Viveksandeep Thoguluva Chandrasekhar, Bilal Mohammad, Divyanshoo Kohli, Michael Vaezi, Philip O Katz & Prateek Sharma. (2020) Proton pump inhibitors do not increase the risk of dementia: a systematic review and meta-analysis of prospective studies. Diseases of the Esophagus 33:10.
Crossref
Yehia Y Mishriki. (2020) PPI-induced hypomagnesemia with secondary hypoparathyroidism and posterior reversible encephalopathy syndrome restricted to the cerebellum. Case Reports International 9:2, pages 1-4.
Crossref
Wisit Cheungpasitporn, Charat Thongprayoon, Api Chewcharat, Tananchai Petnak, Michael A. Mao, Paul W. Davis, Tarun Bathini, Saraschandra Vallabhajosyula, Fawad Qureshi & Stephen B. Erickson. (2020) Hospital-Acquired Dysmagnesemia and In-Hospital Mortality. Medical Sciences 8:3, pages 37.
Crossref
Periklis Katopodis, Emmanouil Karteris & Konstantinos P. Katopodis. (2020) Pathophysiology of Drug-Induced Hypomagnesaemia. Drug Safety 43:9, pages 867-880.
Crossref
Laurentine Boom, Mireille Edens & Bas Rinia. (2020) Reflux finding score and reflux symptom index as potential predictors for proton pump inhibitor response in globus pharyngeus patients: A prospective study. Auris Nasus Larynx 47:4, pages 609-615.
Crossref
Angelita C Melo, Antonio Mendes, Carla Serra, Cassyano Correr, Hellen Maniero, José Ruben Bonfim, Josélia Frade, Juliana Ferreira, Michel Otuki, Thaís Teles de Souza & Wálleri Reis. 2020. Guia de prática clínica: sinais e sintomas do trato gastrointestinal: azia (acidez/pirose) e dispepsia. Guia de prática clínica: sinais e sintomas do trato gastrointestinal: azia (acidez/pirose) e dispepsia.
Ziyad Al-Aly, Geetha Maddukuri & Yan Xie. (2020) Proton Pump Inhibitors and the Kidney: Implications of Current Evidence for Clinical Practice and When and How to Deprescribe. American Journal of Kidney Diseases 75:4, pages 497-507.
Crossref
Jean-Luc Raoul, Julien Edeline, Marine Gilabert, Hélène Senellart & Jean-Sébastien Frenel. (2020) Inhibiteurs de la pompe à protons (IPP) et cancers : une association à risques ?. Bulletin du Cancer 107:4, pages 458-464.
Crossref
Yongjing Zhang, Meng Shu, Wenhua Liang, Kun Jiang, Dianxin Zhang, Hong Qiu & Kaichun Wu. (2020) Risk of Serious Ventricular Arrhythmia in Users of Gastrointestinal Medications: A Retrospective Cohort Study in China. Advances in Therapy 37:4, pages 1564-1578.
Crossref
Antonis A. Manolis, Theodora A. Manolis, Helen Melita, Niki Katsiki & Antonis S. Manolis. (2020) Proton pump inhibitors and cardiovascular adverse effects: Real or surreal worries?. European Journal of Internal Medicine 72, pages 15-26.
Crossref
Ippei Kosedo, Akihiro Tokushige, Takuro Takumi, Akiko Yoshikawa, Kiyo Teraguchi, Kenichi Takenouchi, Kouzou Shiraishi, Daisuke Ikeda, Masakazu Imamura, Takeshi Sonoda, Daisuke Kanda, Yoshiyuki Ikeda, Akio Ido & Mitsuru Ohishi. (2020) Use of proton pump inhibitors is associated with an increase in adverse cardiovascular events in patients with hemodialysis: Insight from the kids registry. European Journal of Internal Medicine 72, pages 79-87.
Crossref
Paulien Vinke, Evertine Wesselink, Wout van Orten-Luiten & Klaske van Norren. (2020) The Use of Proton Pump Inhibitors May Increase Symptoms of Muscle Function Loss in Patients with Chronic Illnesses. International Journal of Molecular Sciences 21:1, pages 323.
Crossref
Ya. G. Bozhko, M. V. Arkhipov & N. A. Belokonova. (2020) Study of the Effect of Proton Pump Inhibitors on the Development of Hypomagnesemia in Patients with Paroxysmal Atrial Fibrillation on the Background of Autonomic Sinus Node Dysfunction. Rational Pharmacotherapy in Cardiology 15:6, pages 840-846.
Crossref
Salman Hussain, Ambrish Singh, Saima Zameer, Mohammad Chand Jamali, Harveen Baxi, Syed Obaidur Rahman, Mahtab Alam, Mohammad Altamish, Avinash Kumar Singh, Dasari Anil, Md Sarfaraj Hussain, Adil Ahmad & Abul Kalam Najmi. (2019) No association between proton pump inhibitor use and risk of dementia: Evidence from a meta‐analysis. Journal of Gastroenterology and Hepatology 35:1, pages 19-28.
Crossref
Aaron J. Jaworek. 2020. Laryngopharyngeal and Gastroesophageal Reflux. Laryngopharyngeal and Gastroesophageal Reflux 285 323 .
Charles Muller, Natalie Tapaskar & Robert T. Kavitt. 2020. Foregut Surgery. Foregut Surgery 121 143 .
Rianne M. Douwes, António W. Gomes-Neto, Joëlle C. Schutten, Else van den Berg, Martin H. de Borst, Stefan P. Berger, Daan J. Touw, Eelko Hak, Hans Blokzijl, Gerjan Navis & Stephan J. L. Bakker. (2019) Proton-Pump Inhibitors and Hypomagnesaemia in Kidney Transplant Recipients. Journal of Clinical Medicine 8:12, pages 2162.
Crossref
Yoon Hee Park, Jong Mi Seong, Soyeon Cho, Hye Won Han, Jae Youn Kim, Sook Hee An & Hye Sun Gwak. (2019) Effects of proton pump inhibitor use on risk of Clostridium difficile infection: a hospital cohort study. Journal of Gastroenterology 54:12, pages 1052-1060.
Crossref
Reidar Fossmark, Tom C. Martinsen & Helge L. Waldum. (2019) Adverse Effects of Proton Pump Inhibitors—Evidence and Plausibility. International Journal of Molecular Sciences 20:20, pages 5203.
Crossref
Lingaku Lee, Irene Ramos-Alvarez, Tetsuhide Ito & Robert T. Jensen. (2019) Insights into Effects/Risks of Chronic Hypergastrinemia and Lifelong PPI Treatment in Man Based on Studies of Patients with Zollinger–Ellison Syndrome. International Journal of Molecular Sciences 20:20, pages 5128.
Crossref
Meng H. Yap, Gary Yip, Alex Edwards, Vincent D'Intini & Erica Tong. (2019) Appropriateness of proton pump inhibitor use in patients admitted under the general medical unit. Journal of Pharmacy Practice and Research 49:5, pages 447-453.
Crossref
O. P. Alekseeva & D. V. Pikulev. (2019) Gastroesophageal Reflux Disease and Coronary Heart Disease: Is There a “Mutual Burden” Syndrome?. Russian Journal of Gastroenterology, Hepatology, Coloproctology 29:4, pages 66-73.
Crossref
Andrea Corsonello & Fabrizia Lattanzio. (2019) Cardiovascular and non-cardiovascular concerns with proton pump inhibitors: Are they safe?. Trends in Cardiovascular Medicine 29:6, pages 353-360.
Crossref
Boonphiphop Boonpheng, Charat Thongprayoon, Tarun Bathini, Konika Sharma, Michael A Mao & Wisit Cheungpasitporn. (2019) Proton pump inhibitors and adverse effects in kidney transplant recipients: A meta-analysis. World Journal of Transplantation 9:2, pages 35-47.
Crossref
Sophie Ribiere, Marie-Anne Guillaumot, Amélie Barré, Einas Abou Ali, Maximilien Barret, Stanislas Chaussade & Romain Coriat. (2019) Quel est le VRAI risque au long cours des inhibiteurs de la pompe à protons ?. La Presse Médicale 48:5, pages 503-510.
Crossref
Bonnie He, Bruce Carleton & Mahyar Etminan. (2019) Risk of Gynecomastia with Users of Proton Pump Inhibitors. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 39:5, pages 614-618.
Crossref
Sabine Roman & Peter J. Kahrilas. 2019. Evidence-based Gastroenterology and Hepatology 4e. Evidence-based Gastroenterology and Hepatology 4e 1 20 .
Faheemuddin Ahmed & Abdul Mohammed. (2019) Magnesium: The Forgotten Electrolyte—A Review on Hypomagnesemia. Medical Sciences 7:4, pages 56.
Crossref
K Lapumnuaypol, C Thongprayoon, K Wijarnpreecha, A Tiu & W Cheungpasitporn. (2019) Reply: Risk of fall injury in patients taking proton pump inhibitors—a meta-analysis. QJM: An International Journal of Medicine 112:4, pages 319-319.
Crossref
Shengtao Liao, Li Gan & Zhechuan Mei. (2019) Does the use of proton pump inhibitors increase the risk of hypomagnesemia. Medicine 98:13, pages e15011.
Crossref
A. Tran-Duy, N. J. Connell, F. H. Vanmolkot, P. C. Souverein, N. J. de Wit, C. D. A. Stehouwer, A. W. Hoes, F. de Vries & A. de Boer. (2019) Use of proton pump inhibitors and risk of iron deficiency: a population-based case-control study. Journal of Internal Medicine 285:2, pages 205-214.
Crossref
Michal Novotny, Blanka Klimova & Martin Valis. (2019) PPI Long Term Use: Risk of Neurological Adverse Events?. Frontiers in Neurology 9.
Crossref
Megan Jaynes & Avinash B. Kumar. (2018) The risks of long-term use of proton pump inhibitors: a critical review. Therapeutic Advances in Drug Safety 10, pages 204209861880992.
Crossref
Eiji Kose, Toshiyuki Hirai & Toshiichi Seki. (2019) Change in number of potentially inappropriate medications impacts on the nutritional status in a convalescent rehabilitation setting. Geriatrics & Gerontology International 19:1, pages 44-50.
Crossref
Thawin Srinutta, Api Chewcharat, Kullaya Takkavatakarn, Kearkiat Praditpornsilpa, Somchai Eiam-Ong, Bertrand L. Jaber & Paweena Susantitaphong. (2019) Proton pump inhibitors and hypomagnesemia. Medicine 98:44, pages e17788.
Crossref
Agnes Czibulka. 2019. Laryngopharyngeal Reflux Disease. Laryngopharyngeal Reflux Disease 103 113 .
M T Al-Qaisi, A Kahn, M D Crowell, G E Burdick, M F Vela & F C Ramirez. (2018) Do recent reports about the adverse effects of proton pump inhibitors change providers’ prescription practice?. Diseases of the Esophagus 31:12.
Crossref
Geoffrey Cheminet, Gabrielle Clain, Anne-Sophie Jannot, Brigitte Ranque, Amélie Passeron, Adrien Michon, Gonzalo De Luna, Jean-Luc Diehl, Stéphane Oudard, Christophe Cellier, Alexandre Karras, Benoit Vedié, Caroline Prot-Bertoye, Jacques Pouchot & Jean-Benoît Arlet. (2018) Extreme hypomagnesemia: characteristics of 119 consecutive inpatients. Internal and Emergency Medicine 13:8, pages 1201-1209.
Crossref
Simon Brisebois, Albert Merati & John Paul Giliberto. (2018) Proton pump inhibitors: Review of reported risks and controversies. Laryngoscope Investigative Otolaryngology 3:6, pages 457-462.
Crossref
Stanley L. Marks, Peter H. Kook, Mark G. Papich, M. K. Tolbert & Michael D. Willard. (2018) ACVIM consensus statement: Support for rational administration of gastrointestinal protectants to dogs and cats. Journal of Veterinary Internal Medicine 32:6, pages 1823-1840.
Crossref
Monica Chowdhry, Kuldeep Shah, Suzanne Kemper, David Zekan, William Carter & Brittain McJunkin. (2018) Proton pump inhibitors not associated with hypomagnesemia, regardless of dose or concomitant diuretic use. Journal of Gastroenterology and Hepatology 33:10, pages 1717-1721.
Crossref
Avinash K. Nehra, Jeffrey A. Alexander, Conor G. Loftus & Vandana Nehra. (2018) In Reply—A Relationship Between Proton Pump Inhibitors and Hypomagnesemia?. Mayo Clinic Proceedings 93:10, pages 1530-1531.
Crossref
Amandeep Singh, Gail A. Cresci & Donald F. Kirby. (2018) Proton Pump Inhibitors: Risks and Rewards and Emerging Consequences to the Gut Microbiome. Nutrition in Clinical Practice 33:5, pages 614-624.
Crossref
Peter Fentz Haastrup, Wade Thompson, Jens Søndergaard & Dorte Ejg Jarbøl. (2018) Side Effects of Long-Term Proton Pump Inhibitor Use: A Review. Basic & Clinical Pharmacology & Toxicology 123:2, pages 114-121.
Crossref
Lee Fidler, Nicole Sitzer, Shane Shapera & Prakesh S. Shah. (2018) Treatment of Gastroesophageal Reflux in Patients With Idiopathic Pulmonary Fibrosis. Chest 153:6, pages 1405-1415.
Crossref
Kamonwan Tangvoraphonkchai & Andrew Davenport. (2018) Magnesium and Cardiovascular Disease. Advances in Chronic Kidney Disease 25:3, pages 251-260.
Crossref
Jeffrey H. William, Katelyn Richards & John Danziger. (2018) Magnesium and Drugs Commonly Used in Chronic Kidney Disease. Advances in Chronic Kidney Disease 25:3, pages 267-273.
Crossref
Yoshikazu Kinoshita, Norihisa Ishimura & Shunji Ishihara. (2018) Advantages and Disadvantages of Long-term Proton Pump Inhibitor Use. Journal of Neurogastroenterology and Motility 24:2, pages 182-196.
Crossref
Pietro E. Lazzerini, Iacopo Bertolozzi, Francesco Finizola, Maurizio Acampa, Mariarita Natale, Francesca Vanni, Rosella Fulceri, Alessandra Gamberucci, Marco Rossi, Beatrice Giabbani, Michele Caselli, Ilaria Lamberti, Gabriele Cevenini, Franco Laghi-Pasini & Pier L. Capecchi. (2018) Proton Pump Inhibitors and Serum Magnesium Levels in Patients With Torsades de Pointes. Frontiers in Pharmacology 9.
Crossref
Avinash K. Nehra, Jeffrey A. Alexander, Conor G. Loftus & Vandana Nehra. (2018) Proton Pump Inhibitors: Review of Emerging Concerns. Mayo Clinic Proceedings 93:2, pages 240-246.
Crossref
. (2018) Electrolyte Disturbances in Chronic Alcohol-Use Disorder. New England Journal of Medicine 378:2, pages 202-204.
Crossref
Óskar Ö. Hálfdánarson, Anton Pottegård, Einar S. Björnsson, Sigrún H. Lund, Margret H. Ogmundsdottir, Eiríkur Steingrímsson, Helga M. Ogmundsdottir & Helga Zoega. (2018) Proton-pump inhibitors among adults: a nationwide drug-utilization study. Therapeutic Advances in Gastroenterology 11, pages 175628481877794.
Crossref
Karn Wijarnpreecha, Charat Thongprayoon, Supavit Chesdachai, Panadeekarn Panjawatanana, Patompong Ungprasert & Wisit Cheungpasitporn. (2017) Associations of Proton-Pump Inhibitors and H2 Receptor Antagonists with Chronic Kidney Disease: A Meta-Analysis. Digestive Diseases and Sciences 62:10, pages 2821-2827.
Crossref
C. Prakash Gyawali. (2017) Proton Pump Inhibitors in Gastroesophageal Reflux Disease: Friend or Foe. Current Gastroenterology Reports 19:9.
Crossref
Leonardo Henry Eusebi, Stefano Rabitti, Maria Laura Artesiani, Dania Gelli, Marco Montagnani, Rocco Maurizio Zagari & Franco Bazzoli. (2017) Proton pump inhibitors: Risks of long-term use. Journal of Gastroenterology and Hepatology 32:7, pages 1295-1302.
Crossref
Akiomi Yoshihisa, Mai Takiguchi, Yuki Kanno, Akihiko Sato, Tetsuro Yokokawa, Shunsuke Miura, Satoshi Abe, Tomofumi Misaka, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Shu‐ichi Saitoh & Yasuchika Takeishi. (2017) Associations of Acid Suppressive Therapy With Cardiac Mortality in Heart Failure Patients. Journal of the American Heart Association 6:5.
Crossref
Stephanie M. Toth-Manikowski & Morgan E. Grams. (2017) Proton Pump Inhibitors and Kidney Disease—GI Upset for the Nephrologist?. Kidney International Reports 2:3, pages 297-301.
Crossref
Mark W. Hess, Jeroen H.F. de Baaij, Mark M.T.J. Broekman, Tanya M. Bisseling, Bertram J.T. Haarhuis, Adriaan C.I.T.L. Tan, René H.M. te Morsche, Joost G.J. Hoenderop, René J.M. Bindels & Joost P.H. Drenth. (2017) Common single nucleotide polymorphisms in transient receptor potential melastatin type 6 increase the risk for proton pump inhibitor-induced hypomagnesemia. Pharmacogenetics and Genomics 27:3, pages 83-88.
Crossref
Daniel E. Freedberg, Lawrence S. Kim & Yu-Xiao Yang. (2017) The Risks and Benefits of Long-term Use of Proton Pump Inhibitors: Expert Review and Best Practice Advice From the American Gastroenterological Association. Gastroenterology 152:4, pages 706-715.
Crossref
Gianmauro Numico, Vittorio Fusco, Pierfrancesco Franco & Fausto Roila. (2017) Proton Pump Inhibitors in cancer patients: How useful they are? A review of the most common indications for their use. Critical Reviews in Oncology/Hematology 111, pages 144-151.
Crossref
Anton Kraus. (2017) The Risk of Hypomagnesemia. Deutsches Ärzteblatt international.
Crossref
Steef Kurstjens, Jeroen H F de Baaij, Hacene Bouras, René J M Bindels, Cees J J Tack & Joost G J Hoenderop. (2017) Determinants of hypomagnesemia in patients with type 2 diabetes mellitus. European Journal of Endocrinology 176:1, pages 11-19.
Crossref
Carmelo Scarpignato, Luigi Gatta, Angelo Zullo & Corrado Blandizzi. (2016) Effective and safe proton pump inhibitor therapy in acid-related diseases – A position paper addressing benefits and potential harms of acid suppression. BMC Medicine 14:1.
Crossref
Mee Onn Chai & Adrian Coleman. (2016) Hypomagnesaemia secondary to omeprazole in stage 5 CKD. Journal of Kidney Care 1:3, pages 144-147.
Crossref
Marko Boban, Marinko Zulj, Viktor Persic, Igor Medved, Drazen Zekanovic & Aleksandar Vcev. (2016) Prolonged utilization of proton pump inhibitors in patients with ischemic and valvular heart disease is associated with surgical treatments, weight loss and aggravates anemia. International Journal of Cardiology 219, pages 277-281.
Crossref
Joo-Hark Yi & Sang-Woong Han. (2016) Is hypomagnesemia associated with using proton pump inhibitors?. Kidney Research and Clinical Practice 35:2, pages 128-129.
Crossref
I. Mikolasevic, S. Milic, D. Stimac, L. Zaputovic, V. Lukenda Zanko, T. Gulin, I. Jakopcic, D. Klaric, M. Gulin & L. Orlic. (2016) Is there a relationship between hypomagnesemia and proton-pump inhibitors in patients on chronic hemodialysis?. European Journal of Internal Medicine 30, pages 99-103.
Crossref
T. Sugiyama, K. Watarai, T. Oda, Y. T. Kim & H. Oda. (2016) Proton pump inhibitors and fracture: they impair bone quality and increase fall risk?. Osteoporosis International 27:4, pages 1675-1676.
Crossref
Mustafa Aparci, Ömer Uz, Murat Atalay & Mehmet Uzun. (2016) May hypomagnesaemia; caused by proton pump inhibitor; increase atrial fibrillation risk?. International Journal of Cardiology 207, pages 141.
Crossref
Kyrre Kittang Reiakvam, Marianne Catharina Astor & Bård Reiakvam Kittang. (2016) En kvinne i 70-årene med rask forverring av kognitiv funksjon. Tidsskrift for Den norske legeforening 136:12/13, pages 1096-1098.
Crossref
Cristóbal de la Coba Ortiz, Federico Argüelles Arias, Carlos Martín de Argila de Prados, Javier Júdez Gutiérrez, Antonio Linares Rodríguez, Aida Ortega Alonso, Enrique Rodríguez de Santiago, Manuel Rodríguez-Téllez, María Isabel Vera Mendoza, Lara Aguilera Castro, Ángel Álvarez Sánchez, Raúl Jesús Andrade Bellido, Fidencio Bao Pérez, Manuel Castro Fernández & Froilán Giganto Tomé. (2016) Proton-pump inhibitors adverse effects: a review of the evidence and position statement by the Sociedad Española de Patología Digestiva. Revista Española de Enfermedades Digestivas 108, pages 207-224.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.