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Methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and diabetic nephropathy susceptibility in patients with type 2 diabetes mellitus

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Pages 1247-1259 | Received 08 Apr 2015, Accepted 11 Jun 2015, Published online: 10 Jul 2015

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Arzu Ay, Nevra Alkanli, Tammam Sipahi, Tevfik Gulyasar, Sedat Ustundag, Sibel Guldiken & Necdet Sut. (2018) Investigation of the relationship between MTHFR, IRS and CALCA gene polymorphisms and development of diabetic nephropathy in patients with type 2 diabetes mellitus. Biotechnology & Biotechnological Equipment 32:5, pages 1257-1265.
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Shanel Raghubeer & Tandi E. Matsha. (2021) Methylenetetrahydrofolate (MTHFR), the One-Carbon Cycle, and Cardiovascular Risks. Nutrients 13:12, pages 4562.
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Zuray Corredor, Miguel Inácio da Silva Filho, Lara Rodríguez-Ribera, Antonia Velázquez, Alba Hernández, Calogerina Catalano, Kari Hemminki, Elisabeth Coll, Irene Silva, Juan Manuel Diaz, José Ballarin, Martí Vallés Prats, Jordi Calabia Martínez, Asta Försti, Ricard Marcos & Susana Pastor. (2020) Genetic Variants Associated with Chronic Kidney Disease in a Spanish Population. Scientific Reports 10:1.
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Hsueh-Lu Chang, Guei-Rung Chen, Po-Jen Hsiao, Chih-Chien Chiu, Ming-Cheng Tai, Chung-Cheng Kao, Dung-Jang Tsai, Hao Su, Yu-Hsuan Chen, Wei-Teing Chen & Sui-Lung Su. (2020) Decisive evidence corroborates a null relationship between MTHFR C677T and chronic kidney disease. Medicine 99:29, pages e21045.
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Saeedeh Asgarbeik, Farideh Razi, Ensieh Nasli-Esfahani, Samaneh Enayati, SeyedAbdolhamid Angaji, Marzieh Arshadi Mashkani, Katayoon Forouzanfar & Mahsa Mohammad Amoli. (2019) Investigating the association of rs2346061 (CNDP1), rs7577 (CNDP2), and rs1801133 (MTHFR) variants and homocysteine level with diabetic nephropathy in an Iranian population. Gene Reports 16, pages 100443.
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Harvest F. Gu. (2019) Genetic and Epigenetic Studies in Diabetic Kidney Disease. Frontiers in Genetics 10.
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Gnanasambandan Ramanathan, Bollimpalli Harichandana, Suresh Kannan, Ramprasad Elumalai & Paul SFD. (2019) Association between end-stage diabetic nephropathy and MTHFR (C677T and A1298C) gene polymorphisms. Nephrology 24:2, pages 155-159.
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Liang Ma, Yongwei Jiang, Xiaomu Kong, Qian Liu, Hailing Zhao, Tingting Zhao, Yongtong Cao & Ping Li. (2018) Interaction of MTHFR C677T polymorphism with smoking in susceptibility to diabetic nephropathy in Chinese men with type 2 diabetes. Journal of Human Genetics 64:1, pages 23-28.
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Harvest F. Gu. 2019. Handbook of Nutrition, Diet, and Epigenetics. Handbook of Nutrition, Diet, and Epigenetics 865 884 .
K. Nithya, W. Isabel, T. Angeline, A.S. Priscilla, H. Shakila & A.J. Asirvatham. (2017) MTHFR C677T gene polymorphism in Type 2 diabetes mellitus patients with and without vascular complications: A case-control study. Meta Gene 14, pages 79-84.
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Nicola Wanner & Wibke Bechtel-Walz. (2017) Epigenetics of kidney disease. Cell and Tissue Research 369:1, pages 75-92.
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Harvest F. Gu. 2017. Handbook of Nutrition, Diet, and Epigenetics. Handbook of Nutrition, Diet, and Epigenetics 1 20 .
Timothy M E Davis, S A Paul Chubb & Wendy A Davis. (2016) The relationship between estimated glomerular filtration rate trajectory and all-cause mortality in type 2 diabetes: the Fremantle Diabetes Study. European Journal of Endocrinology 175:4, pages 273-285.
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Man-Yi Sun, Li Zhang, Song-Li Shi & Jing-Na Lin. (2016) Associations between Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms and Non-Alcoholic Fatty Liver Disease (NAFLD) Risk: A Meta-Analysis. PLOS ONE 11:4, pages e0154337.
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