Advanced search
Publication Cover
Pediatric Hematology and Oncology Volume 28, 2011 - Issue 7
Submit an article Journal homepage
329
Views
28
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE Solid Tumors

Potential Role for Valproate in the Treatment of High-Risk Brain Tumors of Childhood—Results from a Retrospective Observational Cohort Study

Francisco Helder Cavalcante FelixPediatric Hemato-oncology Service, Hospital Infantil Albert Sabin, Fortaleza, CE, BrazilCorrespondence[email protected]
,
Nadia Mendonça TrompieriPediatric Hemato-oncology Service, Hospital Infantil Albert Sabin, Fortaleza, CE, Brazil
,
Orlandira Leite de AraujoPediatric Hemato-oncology Service, Hospital Infantil Albert Sabin, Fortaleza, CE, Brazil
,
Karine Martins da TrindadePediatric Hemato-oncology Service, Hospital Infantil Albert Sabin, Fortaleza, CE, Brazil
&
Juvenia Bezerra FonteneleDepartment of Pharmacy, Faculdade de Farmacia, Odontologia e Enfermagem, Universidade Federal do Ceará, Fortaleza, CE, Brazil
Pages 556-570 | Received 03 Jan 2011, Accepted 14 Feb 2011, Published online: 24 Jun 2011

Citations (28)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

R. J. Head, M. F. Fay, L. Cosgrove, K. Y. C. Fung, D. Rundle-Thiele & J. H. Martin. (2017) Persistence of DNA adducts, hypermutation and acquisition of cellular resistance to alkylating agents in glioblastoma. Cancer Biology & Therapy 18:12, pages 917-926.
Read now

Articles from other publishers (27)

Natália Hogetop Freire, Mariane da Cunha Jaeger, Caroline Brunetto de Farias, Carolina Nör, Barbara Kunzler Souza, Lauro Gregianin, André Tesainer Brunetto & Rafael Roesler. (2023) Targeting the epigenome of cancer stem cells in pediatric nervous system tumors. Molecular and Cellular Biochemistry.
Crossref
Kasra Mirzaie, Anna Burns-Gebhart, Marcel Meyerheim, Annette Sander & Norbert Graf. (2022) Emotion Regulation Flexibility and Electronic Patient-Reported Outcomes: A Framework for Understanding Symptoms and Affect Dynamics in Pediatric Psycho-Oncology. Cancers 14:16, pages 3874.
Crossref
Safwan Alomari, Irma Zhang, Adrian Hernandez, Caitlin Y. Kraft, Divyaansh Raj, Jayanidhi Kedda & Betty Tyler. (2021) Drug Repurposing for Glioblastoma and Current Advances in Drug Delivery—A Comprehensive Review of the Literature. Biomolecules 11:12, pages 1870.
Crossref
Filippo Gagliardi, Pierfrancesco De Domenico, Silvia Snider, Edoardo Pompeo, Francesca Roncelli, Lina Raffaella Barzaghi, Michele Bailo, Martina Piloni, Alfio Spina, Andrei Fodor, Giulia Berzero, Nadia Di Muzio, Massimo Filippi, Gaetano Finocchiaro & Pietro Mortini. (2021) Gamma Knife radiosurgery as primary treatment of low-grade brainstem gliomas: A systematic review and metanalysis of current evidence and predictive factors. Critical Reviews in Oncology/Hematology 168, pages 103508.
Crossref
Tamás Mezei, Dávid Mészáros, Péter Pollner, Attila Bagó, Imre Fedorcsák, Péter Banczerowski & László Sipos. (2021) A valproátterápia túlélésre gyakorolt hatása gliomás betegekben. Orvosi Hetilap 162:24, pages 960-967.
Crossref
Gholamhossein Sodeifian, Nedasadat Saadati Ardestani, Seyed Ali Sajadian, Mohammad Reza Golmohammadi & Alireza Fazlali. (2020) Prediction of Solubility of Sodium Valproate in Supercritical Carbon Dioxide: Experimental Study and Thermodynamic Modeling. Journal of Chemical & Engineering Data 65:4, pages 1747-1760.
Crossref
Rebecca Pötschke, Gerrit Gielen, Torsten Pietsch, Christof Kramm, Jan-Henning Klusmann, Stefan Hüttelmaier & Caspar D. Kühnöl. (2019) Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro. Pediatric Research 87:4, pages 669-676.
Crossref
. (2020) Carboplatin/vincristine. Reactions Weekly 1791:1, pages 57-57.
Crossref
Roberta Rudà, Francesca Mo & Alessia Pellerino. (2020) Epilepsy in brain metastasis: an emerging entity. Current Treatment Options in Neurology 22:2.
Crossref
Roberta Rudà, Alessia Pellerino & Riccardo Soffietti. 2020. Central Nervous System Metastases. Central Nervous System Metastases 117 125 .
Marta Maschio, Umberto Aguglia, Giuliano Avanzini, Paola Banfi, Carla Buttinelli, Giuseppe Capovilla, Marina Maria Luisa Casazza, Gabriella Colicchio, Antonietta Coppola, Cinzia Costa, Filippo Dainese, Ornella Daniele, Roberto De Simone, Marica Eoli, Sara Gasparini, Anna Teresa Giallonardo, Angela La Neve, Andrea Maialetti, Oriano Mecarelli, Marta Melis, Roberto Michelucci, Francesco Paladin, Giada Pauletto, Marta Piccioli, Stefano Quadri, Federica Ranzato, Rosario Rossi, Andrea Salmaggi, Riccardo Terenzi, Paolo Tisei, Flavio Villani, Paolo Vitali, Lucina Carla Vivalda, Gaetano Zaccara, Alessia Zarabla & Ettore Beghi. (2019) Management of epilepsy in brain tumors. Neurological Sciences 40:10, pages 2217-2234.
Crossref
Sze Kiat Tan, Anna Jermakowicz, Adnan K. Mookhtiar, Charles B. Nemeroff, Stephan C. Schürer & Nagi G. Ayad. (2018) Drug Repositioning in Glioblastoma: A Pathway Perspective. Frontiers in Pharmacology 9.
Crossref
Clare L. Killick-Cole, William G. B. Singleton, Alison S. Bienemann, Daniel J. Asby, Marcella J. Wyatt, Lisa J. Boulter, Neil U. Barua & Steven S. Gill. (2017) Repurposing the anti-epileptic drug sodium valproate as an adjuvant treatment for diffuse intrinsic pontine glioma. PLOS ONE 12:5, pages e0176855.
Crossref
Takuya Furuta, Hemragul Sabit, Yu Dong, Katsuyoshi Miyashita, Masashi Kinoshita, Naoyuki Uchiyama, Yasuhiko Hayashi, Yutaka Hayashi, Toshinari Minamoto & Mitsutoshi Nakada. (2017) Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma. Oncotarget 8:14, pages 22811-22824.
Crossref
Sabine Hoja, Markus Schulze, Michael Rehli, Martin Proescholdt, Christel Herold-Mende, Peter Hau & Markus J. Riemenschneider. (2016) Molecular dissection of the valproic acid effects on glioma cells. Oncotarget 7:39, pages 62989-63002.
Crossref
Michael F. Fay, Richard Head, Peter Sminia, Nicholas Dowson, Leah Cosgrove, Stephen E. Rose & Jenny H. Martin. (2016) Valproate in Adjuvant Glioblastoma Treatment. Journal of Clinical Oncology 34:25, pages 3105-3107.
Crossref
. (2016) Highlights from the Literature. Neuro-Oncology 18:5, pages 605-608.
Crossref
Navid Redjal, Clemens Reinshagen, Andrew Le, Brian P. Walcott, Erin McDonnell, Jorg Dietrich & Brian V. Nahed. (2016) Valproic acid, compared to other antiepileptic drugs, is associated with improved overall and progression-free survival in glioblastoma but worse outcome in grade II/III gliomas treated with temozolomide. Journal of Neuro-Oncology 127:3, pages 505-514.
Crossref
Caroline HappoldThierry GorliaOlivier ChinotMark R. GilbertL. Burt NaborsWolfgang WickStephanie L. PughMonika HegiTimothy CloughesyPatrick RothDavid A. ReardonJames R. PerryMinesh P. MehtaRoger StuppMichael Weller. (2016) Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma. Journal of Clinical Oncology 34:7, pages 731-739.
Crossref
Michael Fay, Richard Head & Jennifer Martin. (2015) Where is the radiobiology and pharmacology research to improve outcomes in glioblastoma?. Journal of Neuro-Oncology 124:1, pages 1-3.
Crossref
Marta Mellai, Monica Cattaneo, Alessandra Maria Storaci, Laura Annovazzi, Paola Cassoni, Antonio Melcarne, Pasquale De Blasio, Davide Schiffer & Ida Biunno. (2015) SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy . Oncotarget 6:14, pages 12452-12467.
Crossref
Abdel Nasser Hosein, Yi Chieh Lim, Bryan Day, Brett Stringer, Stephen Rose, Richard Head, Leah Cosgrove, Peter Sminia, Michael Fay & Jennifer H. Martin. (2015) The effect of valproic acid in combination with irradiation and temozolomide on primary human glioblastoma cells. Journal of Neuro-Oncology 122:2, pages 263-271.
Crossref
Francisco Helder Cavalcante Felix, Orlandira Leite de Araujo, Karine Martins da Trindade, Nadia Mendonça Trompieri & Juvenia Bezerra Fontenele. (2013) Retrospective evaluation of the outcomes of children with diffuse intrinsic pontine glioma treated with radiochemotherapy and valproic acid in a single center. Journal of Neuro-Oncology 116:2, pages 261-266.
Crossref
Rejin Kebudi & Fatma Betul Cakir. (2013) Management of Diffuse Pontine Gliomas in Children: Recent Developments. Pediatric Drugs 15:5, pages 351-362.
Crossref
M. Weller. (2013) Are we ready for a randomized trial of valproic acid in newly diagnosed glioblastoma?. Neuro-Oncology 15:7, pages 809-810.
Crossref
M. Kerkhof, J. C. M. Dielemans, M. S. van Breemen, H. Zwinkels, R. Walchenbach, M. J. Taphoorn & C. J. Vecht. (2013) Effect of valproic acid on seizure control and on survival in patients with glioblastoma multiforme. Neuro-Oncology 15:7, pages 961-967.
Crossref
F. H. C. Felix, O. L. de Araujo, K. M. da Trindade, N. M. Trompieri & J. B. Fontenele. (2012) Survival of children with malignant brain tumors receiving valproate: a retrospective study. Child's Nervous System 29:2, pages 195-197.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.