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Autoimmunity Volume 30, 1999 - Issue 2
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Original Article

Detection of Anti-LKM-1(Anti-CYP2D6) by an: Enzyme-Linked Immunosorbent Assay in Adult Patients with Chronic Liver Diseases

Hiroshi Miyakawa Fourth Department of Internal Medicine, Teikyo University School of Medicine, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki-shi, Kanagawa, 213-8507, Japan
,
Eriko Kikazawa Fourth Department of Internal Medicine, Teikyo University School of Medicine, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki-shi, Kanagawa, 213-8507, Japan
,
Kazuhiro Abe Fourth Department of Internal Medicine, Teikyo University School of Medicine, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki-shi, Kanagawa, 213-8507, Japan
,
Kentaro Kikuchi Fourth Department of Internal Medicine, Teikyo University School of Medicine, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki-shi, Kanagawa, 213-8507, Japan
,
Hirotoshi Fujikawa Fourth Department of Internal Medicine, Teikyo University School of Medicine, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki-shi, Kanagawa, 213-8507, Japan
,
Masanao Matsushita Fourth Department of Internal Medicine, Teikyo University School of Medicine, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki-shi, Kanagawa, 213-8507, Japan
,
Naomi Kawaguchi Fourth Department of Internal Medicine, Teikyo University School of Medicine, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki-shi, Kanagawa, 213-8507, Japan
,
Toshio Morizane Department of Internal Medicine, Kanagawa Dental College, 82 Inaoka-cho, Yokosuka-shi, Kanagawa, 238-8580, Japan
,
Kazuhiko Ohya MBL, 1063-103 Ohhara, Terasawaoka, Ina-shi, Nagano, 396-0002, Japan
&
Makoto Kako Fourth Department of Internal Medicine, Teikyo University School of Medicine, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki-shi, Kanagawa, 213-8507, Japan
 show all
Pages 107-114 | Received 13 Aug 1998, Accepted 12 Jan 1999, Published online: 07 Jul 2009

Citations (14)

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Read on this site (2)

Bo Wang, Li-Ping Yang, Xiao-Zhuang Zhang, Shui-Qing Huang, Mark Bartlam & Shu-Feng Zhou. (2009) New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme. Drug Metabolism Reviews 41:4, pages 573-643.
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Hiroshi Miyakawa, Eriko Kitazawa, Kentaro Kikuchi, Hirotoshi Fujikawa, Naomi Kawaguchi, Kazuhiro Abe, Masanao Matsushita, Hiroshi Matsushima, Toshiko Igarashi, Raleigh W. Hankins & Makoto Kako. (2001) Immunoreactivity to Various Human Cytochrome P450 Proteins of Sera from Patients with Autoimmune Hepatitis, Chronic Hepatitis B, and Chronic Hepatitis C. Autoimmunity 33:1, pages 23-32.
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Articles from other publishers (12)

Shufeng Zhou. 2016. Cytochrome P450 2D6. Cytochrome P450 2D6 341 414 .
Nelly Siller, Gerlinde Egerer, Johanna Weiss & Gerd Mikus. (2013) Prolonged sedation of lorazepam due to absent UGT2B4/2B7 glucuronidation. Archives of Toxicology 88:1, pages 179-180.
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Chiara Zingaretti, Milena Arigò, Angela Cardaci, Monica Moro, Mariacristina Crosti, Antonella Sinisi, Elisa Sugliano, Cristina Cheroni, Francesco Marabita, Renzo Nogarotto, Raoul Jean Pierre Bonnal, Paolo Marcatili, Maurizio Marconi, Annalinda Zignego, Paolo Muratori, Pietro Invernizzi, Piero Colombatto, Maurizia Brunetto, Ferruccio Bonino, Raffaele De Francesco, Jens Geginat, Massimiliano Pagani, Luigi Muratori, Sergio Abrignani & Mauro Bombaci. (2012) Identification of New Autoantigens by Protein Array Indicates a Role for IL4 Neutralization in Autoimmune Hepatitis. Molecular & Cellular Proteomics 11:12, pages 1885-1897.
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Soo Ki Kim, Masahide Tojo, Takanobu Hayakumo, Katsutoshi Kuriyama, Satoki Yasumura, Syuji Hiramoto, Kazunori Hasegawa, Masahiko Kondo, Koji Nishikawa, Naoki Miyake & Yukio Osaki. (2011) A case of type II autoimmune hepatitis induced by hepatitis A virus infection. Kanzo 52:8, pages 503-509.
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Qifeng SongGuozhen LiuShaohui HuYan ZhangYong TaoYuning HanHaipan ZengWei HuangFang LiPeng ChenJianhui ZhuChaojun HuShulan ZhangYongzhe LiHeng ZhuLin Wu. (2009) Novel Autoimmune Hepatitis-Specific Autoantigens Identified Using Protein Microarray Technology. Journal of Proteome Research 9:1, pages 30-39.
Crossref
Takashi Kato, Hiroshi Miyakawa & Miyuki Ishibashi. (2004) Frequency and significance of anti-glutathione S-transferase autoantibody (anti-GST A1-1) in autoimmune hepatitis. Journal of Autoimmunity 22:3, pages 211-216.
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Moshe Tom, C.R Myers & Michael R Waterman. (2002) Evaluating molar CYP1A level in fish hepatic microsomes by competitive ELISA using recombinant membrane-free CYP1A standard protein. Aquatic Toxicology 59:1-2, pages 101-114.
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Masahiro Kimura, Ke-ita Tatsumi, Hisato Tada, Yukiko Izumi, Akira Kaneko, Michio Kato, Manabu Masuzawa, Masaki Ikemoto, Yoshiyasu Yabusaki, Yoh Hidaka & Nobuyuki Amino. (2002) Anti-CYP2D6 antibodies detected by quantitative radioligand assay and relation to antibodies to liver-specific arginase in patients with autoimmune hepatitis. Clinica Chimica Acta 316:1-2, pages 155-164.
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Eriko Kitazawa, Toshiko Igarashi, Naomi Kawaguchi, Hiroshi Matsushima, Yumi Kawashima, Raleigh W Hankins & Hiroshi Miyakawa. (2001) Differences in Anti-LKM-1 Autoantibody Immunoreactivity to CYP2D6 Antigenic Sites Between Hepatitis C Virus-negative and -positive Patients. Journal of Autoimmunity 17:3, pages 243-249.
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Yoshihiko Iijima, Takanobu Kato, Hiroshi Miyakawa, Masataka Ogino, Makoto Mizuno, Kanji Sugihara, Takahiro Ando, Kei Fujiwara, Etsuro Orito, Ryuzo Ueda & Masashi Mizokami. (2001) Effect of interferon therapy on Japanese chronic hepatitis C virus patients with anti‐liver/kidney microsome autoantibody type 1. Journal of Gastroenterology and Hepatology 16:7, pages 782-788.
Crossref
Albert J. Czaja. (2000) Autoimmune liver disease. Current Opinion in Gastroenterology 16:3, pages 262-270.
Crossref
Minako Hijikata, Hiroshi Miyakawa, Masanao Matsushita, Makoto Kako, Yasuhiko Ohta & Shunji Mishiro. (2000) CYP2D6 Polymorphism and the Presence of Anti-LKM-1 in Patients with Chronic Hepatitis C. Biochemical and Biophysical Research Communications 270:3, pages 922-926.
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