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Immunopharmacology and Immunotoxicology Volume 22, 2000 - Issue 2
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Research Article

PSK and OK-432-Induced Immunomodulation of Inducible Nitric Oxide (NO) Synthase Gene Expression in Mouse Peritoneal Polymorphonuclear Leukocytes and NO-Mediated Cytotoxicity

Kiyoshi Asai First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, 602-0841, Japan
,
Haruki Kato First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, 602-0841, Japan
,
Kunitaka Hirose Biomedical Research Institute, Kureha Chemical Industries Co., 3-26-2, Hyakunin-cho, Shinjuku-ku, Tokyo, 169-0073, Japan
,
Keiko Akaogi Biomedical Research Institute, Kureha Chemical Industries Co., 3-26-2, Hyakunin-cho, Shinjuku-ku, Tokyo, 169-0073, Japan
,
Shigeru Kimura First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, 602-0841, Japan
,
Shigehiko Mukai First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, 602-0841, Japan
,
Mamoru Inoue First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, 602-0841, Japan
,
Yoshiharu Yamamura First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, 602-0841, Japan
,
Hajime Sano First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, 602-0841, Japan
,
Shigeru Sugino First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, 602-0841, Japan
,
Toshikazu Yoshikawa First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, 602-0841, Japan
&
Motoharu Kondo First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, 602-0841, Japan
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Pages 221-235 | Published online: 27 Sep 2008

Citations (8)

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Yonggang Tan, Yiming Meng, Zuozhou Wang, Fengping Shan, Qiushi Wang & Ning Zhang. (2012) Maturation of morphology, phenotype and functions of murine bone marrow-derived dendritic cells(DCs) induced by polysaccharide Kureha(PSK). Human Vaccines & Immunotherapeutics 8:12, pages 1808-1816.
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Articles from other publishers (7)

Solomon Habtemariam. (2020) Trametes versicolor (Synn. Coriolus versicolor) Polysaccharides in Cancer Therapy: Targets and Efficacy. Biomedicines 8:5, pages 135.
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Eva Jiménez-Medina, Enrique Berruguilla, Irene Romero, Ignacio Algarra, Antonia Collado, Federico Garrido & Angel Garcia-Lora. (2008) The immunomodulator PSK induces in vitro cytotoxic activity in tumour cell lines via arrest of cell cycle and induction of apoptosis. BMC Cancer 8:1.
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Paul Cimoch, Susan Allen-Evenson, Jill Place, David Grotto & Ellyn Silverman. 2006. Integrating Therapeutic and Complementary Nutrition. Integrating Therapeutic and Complementary Nutrition.
Tetsuya Oshikawa, Masato Okamoto, Tomoyuki Tano, Sharif Uddin Ahmed, Akiko Sasai, Shin Kan, Yoichiro Moriya, Yoshiki Ryoma, Motoo Saito & Mitsunobu Sato. (2006) Involvement of nitric oxide in anti-tumor effects of OK-432, a streptococcal anti-tumor immunotherapeutic agent. International Immunopharmacology 6:5, pages 764-773.
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Eva Jim�nez, Angel Garcia-Lora, Marisol Martinez & Federico Garrido. (2004) Identification of the protein components of protein-bound polysaccharide (PSK) that interact with NKL cells. Cancer Immunology, Immunotherapy 54:4, pages 395-399.
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C.K. Wong, P.S. Tse, E.L.Y. Wong, P.C. Leung, K.P. Fung & C.W.K. Lam. (2004) Immunomodulatory effects of Yun Zhi and Danshen capsules in health subjects—a randomized, double-blind, placebo-controlled, crossover study. International Immunopharmacology 4:2, pages 201-211.
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Robert Gyurko, Gabriel Boustany, Paul L. Huang, Alpdogan Kantarci, Thomas E. Van Dyke, Caroline A. Genco & Frank C. GibsonIIIIII. (2003) Mice Lacking Inducible Nitric Oxide Synthase Demonstrate Impaired Killing of Porphyromonas gingivalis . Infection and Immunity 71:9, pages 4917-4924.
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