Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 22, 2010 - Issue 13
256
Views
27
CrossRef citations to date
0
Altmetric
Original Article

Inhalation carcinogenicity and toxicity of 1,2-dichloropropane in rats

, , , , , & show all
Pages 1116-1126 | Received 31 Aug 2010, Accepted 22 Sep 2010, Published online: 12 Nov 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Makoto Take, Michiharu Matsumoto, Tetsuya Takeuchi, Mitsuru Haresaku, Hitomi Kondo, Hideki Senoh, Yumi Umeda, Takeji Takamura-Enya & Shoji Fukushima. (2014) Inhalation exposure to 1,2-dichloropropane: Distribution of blood and tissue concentrations of 1,2-dichloropropane in rats during and after exposure. Journal of Environmental Science and Health, Part A 49:12, pages 1341-1348.
Read now
Michiharu Matsumoto, Yumi Umeda, Makoto Take, Tomoshi Nishizawa & Shoji Fukushima. (2013) Subchronic toxicity and carcinogenicity studies of 1,2-dichloropropane inhalation to mice. Inhalation Toxicology 25:8, pages 435-443.
Read now

Articles from other publishers (25)

Qiuyu Pang, Lexin Zheng, Ruoyu Huang, Heng Xu, Chong Pan, Zhiyong Wang & Tao Wang. (2023) Acute 1,2-Dichloropropane Poisoning due to Ingestion of Rubber Cement. American Journal of Forensic Medicine & Pathology 44:4, pages 345-349.
Crossref
Heather N. Lynch, Jordan S. Kozal, Melissa J. Vincent, Rachel D. Freid, Evan M. Beckett, Sarah Brown, Claire Mathis, Rita S. Schoeny & Andrew Maier. (2023) Systematic review of the human health hazards of propylene dichloride. Regulatory Toxicology and Pharmacology 144, pages 105468.
Crossref
Jordan S. Kozal, Heather N. Lynch, Joanna Klapacz, Rita S. Schoeny, Paul A. Jean & Andrew Maier. (2023) Mode of action assessment for propylene dichloride as a human carcinogen. Chemico-Biological Interactions 382, pages 110382.
Crossref
Yusuke Kimura, Frederick Adams Ekuban, Cai Zong, Shigeyuki Sugie, Xiao Zhang, Ken Itoh, Masayuki Yamamoto, Sahoko Ichihara, Seiichiroh Ohsako & Gaku Ichihara. (2023) Role of Nrf2 in 1,2-dichloropropane-induced cell proliferation and DNA damage in the mouse liver. Toxicological Sciences 195:1, pages 28-41.
Crossref
Masami IshidoMasami Ishido. 2023. Health Risk Assessment of Environmental Chemicals. Health Risk Assessment of Environmental Chemicals 99 106 .
Jose D. Suarez-Torres, Camilo A. Orozco & Carlos E. Ciangherotti. (2021) The 2-year rodent bioassay in drug and chemical carcinogenicity testing: Performance, utility, and configuration for cancer hazard identification. Journal of Pharmacological and Toxicological Methods 110, pages 107070.
Crossref
Abigail Ekuban, Cai Zong, Frederick Adams Ekuban, Yusuke Kimura, Ryoya Takizawa, Kota Morikawa, Kazuo Kinoshita, Sahoko Ichihara, Seiichiroh Ohsako & Gaku Ichihara. (2021) Role of Macrophages in Cytotoxicity, Reactive Oxygen Species Production and DNA Damage in 1,2-Dichloropropane-Exposed Human Cholangiocytes In Vitro. Toxics 9:6, pages 128.
Crossref
Xiao Zhang, Kota Morikawa, Yurie Mori, Cai Zong, Lingyi Zhang, Edwin Garner, Chinyen Huang, Wenting Wu, Jie Chang, Daichi Nagashima, Toshihiro Sakurai, Sahoko Ichihara, Shinji Oikawa & Gaku Ichihara. (2020) Proteomic analysis of liver proteins of mice exposed to 1,2-dichloropropane. Archives of Toxicology 94:8, pages 2691-2705.
Crossref
Meiying Jin, Youngeun Hong, Hyunji Lee, Quangdon Tran, Hyeonjeong Cho, Minhee Kim, So Hee Kwon, Nak Heon Kang, Jisoo Park & Jongsun Park. (2019) 1,2-Dichloropropane (1,2-DCP)-Induced Angiogenesis in Dermatitis. Toxicological Research 35:4, pages 361-369.
Crossref
Cai Zong, Yusuke Kimura, Kazuo Kinoshita, Shigetada Takasu, Xiao Zhang, Toshihiro Sakurai, Yoshitaka Sekido, Sahoko Ichihara, Ginji Endo & Gaku Ichihara. (2019) Exposure to 1,2-Dichloropropane Upregulates the Expression of Activation-Induced Cytidine Deaminase (AID) in Human Cholangiocytes Co-Cultured With Macrophages. Toxicological Sciences 168:1, pages 137-148.
Crossref
Xiao Zhang, Cai Zong, Lingyi Zhang, Edwin Garner, Shigeyuki Sugie, Chinyen Huang, Wenting Wu, Jie Chang, Toshihiro Sakurai, Masashi Kato, Sahoko Ichihara, Shinji Kumagai & Gaku Ichihara. (2018) Exposure of Mice to 1,2-Dichloropropane Induces CYP450-Dependent Proliferation and Apoptosis of Cholangiocytes. Toxicological Sciences 162:2, pages 559-569.
Crossref
Tadashi Hirata, Young-Man Cho, Takeshi Toyoda, Jun-ichi Akagi, Isamu Suzuki, Akiyoshi Nishikawa & Kumiko Ogawa. (2017) Lack of in vivo mutagenicity of 1,2-dichloropropane and dichloromethane in the livers of gpt delta rats administered singly or in combination . Journal of Applied Toxicology 37:6, pages 683-691.
Crossref
Tatsushi Toyooka, Yukie Yanagiba, Megumi Suda, Yuko Ibuki & Rui-Sheng Wang. (2017) 1,2-Dichloropropane generates phosphorylated histone H2AX via cytochrome P450 2E1-mediated metabolism. Toxicology Letters 272, pages 60-67.
Crossref
Makoto Take, Tetsuya Takeuchi, Shigeyuki Hirai, Kenji Takanobu, Michiharu Matsumoto, Shoji Fukushima & Jun Kanno. (2017) Distribution of 1,2-dichloropropane in blood and other tissues of rats after oral administration. The Journal of Toxicological Sciences 42:2, pages 121-128.
Crossref
Yukie Yanagiba, Tetsuya Suzuki, Megumi Suda, Rieko Hojo, Frank J Gonzalez, Tamie Nakajima & Rui-Sheng Wang. (2016) Cytochrome P450 2E1 is responsible for the initiation of 1,2-dichloropropane-induced liver damage. Toxicology and Industrial Health 32:9, pages 1589-1597.
Crossref
Sachiyo Mimaki, Yukari Totsuka, Yutaka Suzuki, Chikako Nakai, Masanori Goto, Motohiro Kojima, Hirofumi Arakawa, Shigekazu Takemura, Shogo Tanaka, Shigeru Marubashi, Masahiko Kinoshita, Tomonari Matsuda, Tatsuhiro Shibata, Hitoshi Nakagama, Atsushi Ochiai, Shoji Kubo, Shoji Nakamori, Hiroyasu Esumi & Katsuya Tsuchihara. (2016) Hypermutation and unique mutational signatures of occupational cholangiocarcinoma in printing workers exposed to haloalkanes. Carcinogenesis 37:8, pages 817-826.
Crossref
Yukie Yanagiba, Megumi Suda, Tatushi Toyooka & Rui-Sheng Wang. (2016) Chemical management and occupational cholangiocarcinoma among workers in printing industry. Sangyo Eiseigaku Zasshi SANGYO EISEIGAKU ZASSHI 58:2, pages 78-83.
Crossref
Lingyi Zhang, Cai Zong, Sahoko Ichihara, Hisao Naito, Shinya Toyokuni, Shinji Kumagai & Gaku Ichihara. (2015) A trial to find appropriate animal models of dichloropropane‐induced cholangiocarcinoma based on the hepatic distribution of glutathione S‐transferases. Journal of Occupational Health 57:6, pages 548-554.
Crossref
Kyung-Taek Rim & Cheol-Hong Lim. (2015) Chronic inhalation/carcinogenicity studies and their applications to prevent the occupational cancers: A review of recent reports. Toxicology and Environmental Health Sciences 7:3, pages 171-183.
Crossref
Min Gi, Masaki Fujioka, Shotaro Yamano, Eri Shimomura, Naomi Ishii, Anna Kakehashi, Masanori Takeshita & Hideki Wanibuchi. (2015) Determination of Hepatotoxicity and Its Underlying Metabolic Basis of 1,2-Dichloropropane in Male Syrian Hamsters and B6C3F1 Mice. Toxicological Sciences 145:1, pages 196-208.
Crossref
Yoichi Kawasaki, Chiaki Tsuboi, Kenta Yagi, Miwa Morizane, Yasuyuki Masaoka, Satoru Esumi, Yoshihisa Kitamura & Toshiaki Sendo. (2014) Photoinitiators enhanced 1,2-dichloropropane-induced cytotoxicity in human normal embryonic lung fibroblasts cells in vitro. Environmental Science and Pollution Research 22:6, pages 4763-4770.
Crossref
Min Gi, Masaki Fujioka, Shotaro Yamano, Eri Shimomura, Masayuki Kanki, Satoko Kawachi, Hirokazu Tachibana, Kumiko Tatsumi, He Fang, Naomi Ishii, Anna Kakehashi & Hideki Wanibuchi. (2015) Modifying effects of 1,2-dichloropropane on N-nitrosobis(2-oxopropyl)amine-induced cholangiocarcinogenesis in male Syrian hamsters. The Journal of Toxicological Sciences 40:5, pages 647-656.
Crossref
J. Oltmanns, D. Bunke, W. Jenseit & C. Heidorn. (2014) The impact of REACH on classification for human health hazards. Regulatory Toxicology and Pharmacology 70:2, pages 474-481.
Crossref
Kosei Maemura, Shoji Natsugoe & Sonshin Takao. (2014) Molecular mechanism of cholangiocarcinoma carcinogenesis. Journal of Hepato-Biliary-Pancreatic Sciences 21:10, pages 754-760.
Crossref
Tetsuya Suzuki, Yukie Yanagiba, Megumi Suda & Rui‐Sheng Wang. (2014) Assessment of the Genotoxicity of 1,2‐Dichloropropane and Dichloromethane after Individual and Co‐exposure by Inhalation in Mice. Journal of Occupational Health 56:3, pages 205-214.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.