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Inhalation Toxicology
International Forum for Respiratory Research
Volume 23, 2011 - Issue 3
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Research Article

The role of cardiovascular disease-associated iron overload in Libby amphibole-induced acute pulmonary injury and inflammation

Jonathan ShannahanUniversity of North Carolina Chapel Hill, NC, USA
,
Mette SchladweilerUnited States Environmental Protection Agency, Cardiopulmonary and Immunotoxicology Branch, Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, Research Triangle Park, NC, USA
,
Danielle Padilla-CarlinUniversity of North Carolina Chapel Hill, NC, USA
,
Abraham NyskaTel-Aviv University, Sackler School of Medicine, Timrat, Israel
,
Judy RichardsUnited States Environmental Protection Agency, Analytical Chemistry Core Unit, National Health and Environmental Effects Research Laboratory, Office of Research and Development, Research Triangle Park, NC, USA
,
Andrew GhioUnited States Environmental Protection Agency, Clinical Research Branch, Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, Chapel Hill, NC, USA
,
Stephen GavettUnited States Environmental Protection Agency, Cardiopulmonary and Immunotoxicology Branch, Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, Research Triangle Park, NC, USA
&
Urmila KodavantiUnited States Environmental Protection Agency, Cardiopulmonary and Immunotoxicology Branch, Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, Research Triangle Park, NC, USA
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Pages 129-141 | Received 02 Nov 2010, Accepted 30 Dec 2010, Published online: 10 Mar 2011

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Read on this site (3)

Urmila P. Kodavanti, Allen D. Ledbetter, Ronald F. Thomas, Judy E. Richards, William O. Ward, Mette C. Schladweiler & Daniel L. Costa. (2015) Variability in ozone-induced pulmonary injury and inflammation in healthy and cardiovascular-compromised rat models. Inhalation Toxicology 27:sup1, pages 39-53.
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J. H. Shannahan, M. C. Schladweiler, R. F. Thomas, W. O. Ward, A. J. Ghio, S. H. Gavett & U. P. Kodavanti. (2012) Vascular and Thrombogenic Effects of Pulmonary Exposure to Libby Amphibole. Journal of Toxicology and Environmental Health, Part A 75:4, pages 213-231.
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J.H. Shannahan, A.J. Ghio, M.C. Schladweiler, J.H. Richards, D. Andrews, S.H. Gavett & U.P. Kodavanti. (2012) Transcriptional activation of inflammasome components by Libby amphibole and the role of iron. Inhalation Toxicology 24:1, pages 60-69.
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Articles from other publishers (4)

Danielle J. Carlin, Theodore C. Larson, Jean C. Pfau, Stephen H. Gavett, Arti Shukla, Aubrey Miller & Ronald Hines. (2015) Current Research and Opportunities to Address Environmental Asbestos Exposures. Environmental Health Perspectives 123:8.
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Ágnes Papp, Zsolt Bene, Imre Gáspár, Béla Nagy Jr.László Kádár, Tivadar Márialigeti, Andrea Bánfi, György Baktai, György Balla & Béla Nagy. (2015) Decreased VEGF Level Is Associated with Elevated Ferritin Concentration in Bronchoalveolar Lavage Fluid of Children with Interstitial Lung Diseases. Respiration 90:6, pages 443-450.
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Jonathan H. Shannahan, Oscar Alzate, Witold M. Winnik, Debora Andrews, Mette C. Schladweiler, Andrew J. Ghio, Stephen H. Gavett & Urmila P. Kodavanti. (2012) Acute phase response, inflammation and metabolic syndrome biomarkers of Libby asbestos exposure. Toxicology and Applied Pharmacology 260:2, pages 105-114.
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Jonathan H. Shannahan, Abraham Nyska, Mark Cesta, Mette C.J. Schladweiler, Beena D. Vallant, William O. Ward, Andrew J. Ghio, Stephen H. Gavett & Urmila P. Kodavanti. (2012) Subchronic Pulmonary Pathology, Iron Overload, and Transcriptional Activity after Libby Amphibole Exposure in Rat Models of Cardiovascular Disease. Environmental Health Perspectives 120:1, pages 85-91.
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