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Inhalation Toxicology
International Forum for Respiratory Research
Volume 27, 2015 - Issue 7
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Research Article

Characterization of biochemical, functional and structural changes in mice respiratory organs chronically exposed to cigarette smoke

Hiroyuki TsujiProduct Science Division, R&D Group, Japan Tobacco Inc., Kanagawa, Japan, Correspondence[email protected]
,
Hitoshi FujimotoProduct Science Division, R&D Group, Japan Tobacco Inc., Kanagawa, Japan,
,
Kyeonghee Monica LeeScientific and Regulatory Affairs, JT International S.A., Geneva, Switzerland, and
,
Roger RenneRoger Renne ToxPath Consulting, Sumner, WA, USA
,
Asuka IwanagaProduct Science Division, R&D Group, Japan Tobacco Inc., Kanagawa, Japan,
,
Chigusa OkuboProduct Science Division, R&D Group, Japan Tobacco Inc., Kanagawa, Japan,
,
Saeko OnamiProduct Science Division, R&D Group, Japan Tobacco Inc., Kanagawa, Japan,
,
Ayako Koizumi NomuraProduct Science Division, R&D Group, Japan Tobacco Inc., Kanagawa, Japan,
,
Tomoki NishinoProduct Science Division, R&D Group, Japan Tobacco Inc., Kanagawa, Japan,
&
Hiroyuki YoshimuraProduct Science Division, R&D Group, Japan Tobacco Inc., Kanagawa, Japan,
show all
Pages 342-353 | Received 27 Jan 2015, Accepted 11 May 2015, Published online: 03 Jul 2015

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K. Monica Lee, Julia Hoeng, Sam Harbo, Ulrike Kogel, William Gardner, Michael Oldham, Eric Benson, Marja Talikka, Athanasios Kondylis, Florian Martin, Bjoern Titz, Sam Ansari, Keyur Trivedi, Emmanuel Guedj, Ashraf Elamin, Nikolai V. Ivanov, Patrick Vanscheeuwijck, Manuel C. Peitsch & Willie J. McKinney$suffix/text()$suffix/text(). (2018) Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols. Inhalation Toxicology 30:13-14, pages 553-567.
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Articles from other publishers (11)

Jung‐Min Park, Yoon‐Seok Seo, Sung‐Hwan Kim, Hyeon‐Young Kim, Min‐Seok Kim & Moo‐Yeol Lee. (2023) Impact of inhalation exposure to cigarette smoke on the pathogenesis of pulmonary hypertension primed by monocrotaline in rats. Journal of Applied Toxicology.
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Ulrike Kogel, Ee Tsin Wong, Justyna Szostak, Wei Teck Tan, Francesco Lucci, Patrice Leroy, Bjoern Titz, Yang Xiang, Tiffany Low, Sin Kei Wong, Emmanuel Guedj, Nikolai V. Ivanov, Walter K. Schlage, Manuel C. Peitsch, Arkadiusz Kuczaj, Patrick Vanscheeuwijck & Julia Hoeng. (2021) Impact of whole‐body versus nose‐only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2‐month cigarette smoke exposure study in the ApoE −/− mouse model . Journal of Applied Toxicology 41:10, pages 1598-1619.
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Stefan Hadzic, Cheng-Yu Wu, Marija Gredic, Baktybek Kojonazarov, Oleg Pak, Simone Kraut, Natascha Sommer, Djuro Kosanovic, Friedrich Grimminger, Ralph T. Schermuly, Werner Seeger, Saverio Bellusci & Norbert Weissmann. (2021) The effect of long-term doxycycline treatment in a mouse model of cigarette smoke-induced emphysema and pulmonary hypertension. American Journal of Physiology-Lung Cellular and Molecular Physiology 320:5, pages L903-L915.
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Ashutosh Kumar, Ulrike Kogel, Marja Talikka, Celine Merg, Emmanuel Guedj, Yang Xiang, Athanasios Kondylis, Bjoern Titz, Nikolai V Ivanov, Julia Hoeng, Manuel Peitsch, Joshua Allen, Amit Gupta, Anthony Skowronek & K Monica Lee. (2021) A 7-month inhalation toxicology study in C57BL/6 mice demonstrates reduced pulmonary inflammation and emphysematous changes following smoking cessation or switching to e-vapor products. Toxicology Research and Application 5, pages 239784732199587.
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Hui Wang, Joan Holgate, Selena Bartlett & Nazrul Islam. (2020) Assessment of nicotine release from nicotine-loaded chitosan nanoparticles dry powder inhaler formulations via locomotor activity of C57BL/6 mice. European Journal of Pharmaceutics and Biopharmaceutics 154, pages 175-185.
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V. M. Tkachenko & T. E. Komisova. (2019) Long-Term Effects of Parents’ Passive Smoking on the Morphofunctional Status of Adrenal Glands and Thymus in their Descendants. Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 4:5, pages 345-352.
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Xiaotong Ji, Huifeng Yue, Tingting Ku, Yingying Zhang, Yang Yun, Guangke Li & Nan Sang. (2019) Histone modification in the lung injury and recovery of mice in response to PM2.5 exposure. Chemosphere 220, pages 127-136.
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Wilfried Klein. (2019) Quantitative morphology of the lung and its importance in investigations of pulmonary diseases in mice. Drug Discovery Today: Disease Models 29-30, pages 19-26.
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Joshua Lewis, Kelsey Hirschi, Juan Arroyo, Benjamin Bikman, David Kooyman & Paul Reynolds. (2017) Plausible Roles for RAGE in Conditions Exacerbated by Direct and Indirect (Secondhand) Smoke Exposure. International Journal of Molecular Sciences 18:3, pages 652.
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Flavia Mazzoli-Rocha, Vinícius Rosa Oliveira, Bárbara Chaves Barcellos, Dayse Kelly Molina Moreira, Paulo Hilário Nascimento Saldiva, Débora Souza Faffe & Walter Araújo Zin. (2016) Time-dependency of mice lung recovery after a 4-week exposure to traffic or biomass air pollutants. Respiratory Physiology & Neurobiology 230, pages 16-21.
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Fariz NurwidyaTriya DamayantiFaisal Yunus. (2016) The Role of Innate and Adaptive Immune Cells in the Immunopathogenesis of Chronic Obstructive Pulmonary Disease. Tuberculosis and Respiratory Diseases 79:1, pages 5.
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