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Inhalation Toxicology
International Forum for Respiratory Research
Volume 8, 1996 - Issue 1
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Research Article

Acute Exposure to Low-Level Methyl Tertiary-Butyl Ether (MTBE): Human Reactions and Pharmacokinetic Response

William S. Cain John B. Pierce Laboratory, Yale University, New Haven, Connecticut, USA
,
Brian P. Leaderer John B. Pierce Laboratory, Yale University, New Haven, Connecticut, USA
,
Gary L. Ginsberg TRC Environmental Corporation, Windsor, Connecticut, USA
,
Larry S. Andrews ARCO Chemical Company, Newtown Square, Pennsylvania, USA
,
J. Enrique Cometto-muñiz John B. Pierce Laboratory, Yale University, New Haven, Connecticut, USA
,
Janneane F. Gent John B. Pierce Laboratory, Yale University, New Haven, Connecticut, USA
,
Marion Buck John B. Pierce Laboratory, Yale University, New Haven, Connecticut, USA
,
Larry G. Berglund John B. Pierce Laboratory, Yale University, New Haven, Connecticut, USA
,
Vahid Mohsenin John B. Pierce Laboratory, Yale University, New Haven, Connecticut, USA
,
Edward Monahan John B. Pierce Laboratory, Yale University, New Haven, Connecticut, USA
&
Soren Kjaergaard University of Århus, Århus, Denmark
 show all
Pages 21-48 | Received 02 Feb 1995, Accepted 15 Jun 1995, Published online: 27 Sep 2008

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Douglas McGregor. (2006) Methyl tertiary-Butyl Ether: Studies for Potential Human Health Hazards. Critical Reviews in Toxicology 36:4, pages 319-358.
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Richard L. Doty, J. Enrique Cometto-Muñiz, Alfredo A. Jalowayski, Pamela Dalton, Martin Kendal-Reed & Michael Hodgson. (2004) Assessment of Upper Respiratory Tract and Ocular Irritative Effects of Volatile Chemicals in Humans. Critical Reviews in Toxicology 34:2, pages 85-142.
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Janet Benson, Brad Tibbetts & Edward Barr. (2003) The Uptake, Distribution, Metabolism, and Excretion of Methyl Tertiary-Butyl Ether Inhaled Alone and in Combination with Gasoline Vapor. Journal of Toxicology and Environmental Health, Part A 66:11, pages 1029-1052.
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Articles from other publishers (22)

A'edah Abu-Bakar, Vasilis Vasiliou, Zeljka Popovic & Salmaan H Inayat-Hussain. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 859 874 .
K. H. Schaller & G. Csanády. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 17 .
Jianping Yang, Qinzhi Wei, Xiaochun Peng, Xiaowu Peng, Jianhui Yuan & Dalin Hu. (2016) Relationship between Methyl Tertiary Butyl Ether Exposure and Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study among Petrol Station Attendants in Southern China. International Journal of Environmental Research and Public Health 13:10, pages 946.
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Dalin Hu, Jianping Yang, Yungang Liu, Wenjuan Zhang, Xiaowu Peng, Qinzhi Wei, Jianhui Yuan & Zhiliang Zhu. (2016) Health Risk Assessment for Inhalation Exposure to Methyl Tertiary Butyl Ether at Petrol Stations in Southern China. International Journal of Environmental Research and Public Health 13:2, pages 204.
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Janice S. Lee & Robyn Blain. 2015. Hamilton & Hardy's Industrial Toxicology. Hamilton & Hardy's Industrial Toxicology 643 650 .
Mojtaba Shamsipur, Ali Akbar Miran Beigi, Mohammad Teymouri, Tahereh Poursaberi, S. Mojtaba Mostafavi, Parviz Soleimani, Fereshteh Chitsazian & Shahram Abolhassan Tash. (2011) Biotransformation of methyl tert-butyl ether by human cytochrome P450 2A6. Biodegradation 23:2, pages 311-318.
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K. H. Schaller & G. Csanády. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 19 .
Scott Phillips, Robert B. Palmer & Aaron Brody. (2008) Epidemiology, toxicokinetics, and health effects of methyltert-butyl ether (MTBE). Journal of Medical Toxicology 4:2, pages 115-126.
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David Kim, Melvin E. Andersen, Joachim D. Pleil, Leena A. Nylander-French & James D. Prah. (2007) Refined PBPK model of aggregate exposure to methyl tertiary-butyl ether. Toxicology Letters 169:3, pages 222-235.
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Douglas McGregor. 2007. Fuel Oxygenates. Fuel Oxygenates 331 400 .
Lance Wallace. 2006. Exposure Analysis. Exposure Analysis 395 407 .
Serap Erdal. 2004. Encyclopedia of Energy. Encyclopedia of Energy 821 830 .
Wolfgang Dekant, Ulrike Bernauer, Elisabeth Rosner & Alexander Amberg. (2001) Toxicokinetics of ethers used as fuel oxygenates. Toxicology Letters 124:1-3, pages 37-45.
Crossref
CHIA-WEI LEE, SANDRA N MOHR & CLIFFORD P WEISEL. (2001) Toxicokinetics of human exposure to methyl tertiary-butyl ether (MTBE) following short-term controlled exposures. Journal of Exposure Science & Environmental Epidemiology 11:2, pages 67-78.
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RICHARD E OPIEKUN, NATALIE C G FREEMAN, KATHIE KELLY-MCNEIL, NANCY L FIEDLER & PAUL J LIOY. (2001) Effect of vehicle use and maintenance patterns of a self-described group of sensitive individuals and nonsensitive individuals to methyl tertiary-butyl ether in gasoline. Journal of Exposure Science & Environmental Epidemiology 11:2, pages 79-85.
Crossref
Serap ErdalBernard D. Goldstein. (2000) M ETHYL tert-B UTYL E THER AS A G ASOLINE O XYGENATE : Lessons for Environmental Public Policy . Annual Review of Energy and the Environment 25:1, pages 765-802.
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Jun-Yan Hong, Yong-Yu Wang, Flordeliza Y. Bondoc, Maojung Lee, Chung S. Yang, Wen-Yu Hu & Jinmei Pan. (1999) Metabolism of Methyl tert-butyl Ether and Other Gasoline Ethers by Human Liver Microsomes and Heterologously Expressed Human Cytochromes P450: Identification of CYP2A6 as a Major Catalyst. Toxicology and Applied Pharmacology 160:1, pages 43-48.
Crossref
Irene Tesseraux & G. Koss. 1999. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 332 343 .
L CaprinoG I Togna. (1998) Potential health effects of gasoline and its constituents: A review of current literature (1990-1997) on toxicological data.. Environmental Health Perspectives 106:3, pages 115-125.
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Annsofi Nihlén, Robert Wålinder, Agneta Löf & Gunnar Johanson. (1998) Experimental Exposure to Methyltertiary-Butyl Ether. Toxicology and Applied Pharmacology 148:2, pages 281-287.
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Annsofi Nihlén, Agneta Löf & Gunnar Johanson. (1998) Experimental Exposure to Methyltertiary-Butyl Ether. Toxicology and Applied Pharmacology 148:2, pages 274-280.
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Hari V. Rao & Gary L. Ginsberg. (2006) A Physiologically‐Based Pharmacokinetic Model Assessment of Methyl t ‐Butyl Ether in Groundwater for a Bathing and Showering Determination . Risk Analysis 17:5, pages 583-598.
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