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Growth Factors Volume 30, 2012 - Issue 1
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Articles

Axitinib modulates hypoxia-induced blood–retina barrier permeability and expression of growth factors

Marcus KerntDepartment of Ophthalmology, Ludwig-Maximilians-University, Munich, GermanyCorrespondence[email protected]
,
Sarah ThieleDepartment of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
,
Raffael G. LieglDepartment of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
,
Barbara KerntDepartment of Plastic Surgery, Ludwig-Maximilians-University, Munich, Germany
,
Kirsten EiblDepartment of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
,
Christos HaritoglouDepartment of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
,
Michael W. UlbigDepartment of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
&
Anselm KampikDepartment of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
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Pages 49-61 | Received 19 Jul 2011, Accepted 07 Nov 2011, Published online: 15 Dec 2011

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C. Wertheimer, R. Liegl, M. Kernt, D. Docheva, A. Kampik & K.H. Eibl-Lindner. (2014) EGFR-Blockade With Erlotinib Reduces EGF and TGF-β2 Expression and the Actin-Cytoskeleton Which Influences Different Aspects of Cellular Migration in Lens Epithelial cells. Current Eye Research 39:10, pages 1000-1012.
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Articles from other publishers (12)

Bhavneet Kaur, Bruna Miglioranza Scavuzzi, Steven F Abcouwer & David N Zacks. (2023) A simplified protocol to induce hypoxia in a standard incubator: A focus on retinal cells. Experimental Eye Research 236, pages 109653.
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Andrew H. Dolinko, Marilyn Chwa, Kevin Schneider, Mithalesh K. Singh, Shari Atilano, Jie Wu & M. Cristina Kenney. (2023) Hypoxia-induced transcriptional differences in African and Asian versus European diabetic cybrids. Scientific Reports 13:1.
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Viral S. Kansara, Leroy W. Muya & Thomas A. Ciulla. (2021) Evaluation of Long-Lasting Potential of Suprachoroidal Axitinib Suspension Via Ocular and Systemic Disposition in Rabbits. Translational Vision Science & Technology 10:7, pages 19.
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Andrew H. Dolinko, Marilyn Chwa, Shari R. Atilano & M. Cristina Kenney. (2019) African and Asian Mitochondrial DNA Haplogroups Confer Resistance Against Diabetic Stresses on Retinal Pigment Epithelial Cybrid Cells In Vitro. Molecular Neurobiology 57:3, pages 1636-1655.
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Willem A. Dik, Jeroen Bastiaans & Jan C. van Meurs. 2020. Retinal Pigment Epithelium in Health and Disease. Retinal Pigment Epithelium in Health and Disease 139 160 .
Masahiko Sugimoto, Mineo Kondo, Yuki Kamimoto, Tomoaki Ikeda, Alecia Cutler, Ali Mariya & Bela Anand-Apte. (2019) Changes in VEGF-related factors are associated with presence of inflammatory factors in carbohydrate metabolism disorders during pregnancy. PLOS ONE 14:8, pages e0220650.
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Mariola Lledó Riquelme, Ezequiel Campos‐Mollo & Laura Fernández‐Sánchez. (2018) Topical axitinib is a potent inhibitor of corneal neovascularization. Clinical & Experimental Ophthalmology 46:9, pages 1063-1074.
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Yin‐Siew Lai, Rika Wahyuningtyas, Shin‐Peir Aui & Ko‐Tung Chang. (2018) Autocrine VEGF signalling on M2 macrophages regulates PD ‐L1 expression for immunomodulation of T cells . Journal of Cellular and Molecular Medicine.
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Derrick J. Feenstra, Faye M. Drawnel & Ashwath Jayagopal. 2018. Early Events in Diabetic Retinopathy and Intervention Strategies. Early Events in Diabetic Retinopathy and Intervention Strategies.
Jakob Siedlecki, Christian Wertheimer, Armin Wolf, Raffael Liegl, Claudia Priglinger, Siegfried Priglinger & Kirsten Eibl-Lindner. (2017) Combined VEGF and PDGF inhibition for neovascular AMD: anti-angiogenic properties of axitinib on human endothelial cells and pericytes in vitro. Graefe's Archive for Clinical and Experimental Ophthalmology 255:5, pages 963-972.
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FENGLAN ZHANG, XUEJING MAN, HUAJUN YU, LIMEI LIU & YUANBIN LI. (2015) Synergistic protective effects of escin and low-dose glucocorticoids against vascular endothelial growth factor-induced blood-retinal barrier breakdown in retinal pigment epithelial and umbilical vein endothelial cells. Molecular Medicine Reports 11:2, pages 1372-1377.
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Raffael Liegl, Susanna Koenig, Jakob Siedlecki, Christos Haritoglou, Anselm Kampik & Marcus Kernt. (2014) Temsirolimus Inhibits Proliferation and Migration in Retinal Pigment Epithelial and Endothelial Cells via mTOR Inhibition and Decreases VEGF and PDGF Expression. PLoS ONE 9:2, pages e88203.
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